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ONTOLOGY REPORT - ANNOTATIONS


Term:ionotropic glutamate receptor complex
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Accession:GO:0008328 term browser browse the term
Definition:A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex.



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ionotropic glutamate receptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 part_of TAS
ISO
PMID:11836517
(MGI:3852309|PMID:15207857)
RGD PMID:15207857 PMID:11836517 MGI:3852309, RGD:8554410 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 part_of TAS PMID:11836517 UniProt PMID:11836517 RGD:8554410 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 part_of TAS PMID:11836517 UniProt PMID:11836517 RGD:8554410 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096
JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 part_of TAS PMID:11836517 UniProt PMID:11836517 RGD:8554410 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979
JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 part_of IEA
ISO
GO_REF:0000107
(MGI:3852309|PMID:15207857)
Ensembl
RGD
PMID:15207857 GO_REF:0000107 MGI:3852309 NCBI chr 4:92,415,019...93,892,472
Ensembl chr 4:92,415,230...93,889,355
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 IDA RGD PMID:16540562 RGD:1642470 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 part_of IDA PMID:10627597 UniProt PMID:10627597 RGD:8553571 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
JBrowse link
G Grik4 glutamate ionotropic receptor kainate type subunit 4 TAS RGD PMID:7527545 RGD:734533 NCBI chr 8:42,903,043...43,331,990
Ensembl chr 8:42,905,056...43,193,751
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 part_of IDA PMID:10627597 UniProt PMID:10627597 RGD:8553571 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125
JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D TAS RGD PMID:7512349 RGD:728580 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793
JBrowse link
G Shisa9 shisa family member 9 part_of ISO (MGI:4440391|PMID:20185686) RGD PMID:20185686 MGI:4440391 NCBI chr10:3,335,616...3,629,334 JBrowse link
AMPA glutamate receptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd12 abhydrolase domain containing 12, lysophospholipase part_of ISO (MGI:5440375|PMID:22632720) RGD PMID:22632720 MGI:5440375 NCBI chr 3:139,659,315...139,719,529
Ensembl chr 3:139,659,317...139,719,564
JBrowse link
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase part_of ISO (MGI:5440375|PMID:22632720) RGD PMID:22632720 MGI:5440375 NCBI chr15:16,859,740...16,907,094
Ensembl chr15:16,859,738...16,906,985
JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 part_of IBA
ISO
IDA
PMID:21873635
(MGI:5440375|PMID:22632720)
PMID:19265014
RGD PMID:22632720 PMID:21873635 PMID:19265014 MGI:5440375, RGD:13792537, RGD:8554136 NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227
JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 part_of IDA
ISO
IBA
PMID:19265014
(MGI:5440375|PMID:22632720)
PMID:21873635
RGD PMID:22632720 PMID:19265014 PMID:21873635 MGI:5440375, RGD:8554136, RGD:13792537 NCBI chr 1:177,201,990...177,296,473
Ensembl chr 1:177,201,288...177,297,024
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 part_of IBA
ISO
IDA
PMID:21873635
(MGI:5440375|PMID:22632720)
PMID:19265014
RGD PMID:22632720 PMID:21873635 PMID:19265014 MGI:5440375, RGD:13792537, RGD:8554136 NCBI chr10:92,686,100...92,745,601
Ensembl chr10:92,683,761...92,746,126
JBrowse link
G Cacng5 calcium voltage-gated channel auxiliary subunit gamma 5 part_of IBA
IDA
PMID:21873635
PMID:19265014
GO_Central
UniProt
PMID:21873635 PMID:19265014 RGD:13792537, RGD:8554136 NCBI chr10:92,827,441...92,869,632
Ensembl chr10:92,829,196...92,869,614
JBrowse link
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 part_of IDA
IBA
PMID:19265014
PMID:21873635
UniProt
GO_Central
PMID:19265014 PMID:21873635 RGD:8554136, RGD:13792537 NCBI chr 1:65,800,820...65,831,165
Ensembl chr 1:65,800,355...65,831,006
JBrowse link
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 part_of IDA
IBA
PMID:19265014
PMID:21873635
UniProt
GO_Central
PMID:19265014 PMID:21873635 RGD:8554136, RGD:13792537 NCBI chr 1:65,755,334...65,775,567
Ensembl chr 1:65,755,334...65,779,089
JBrowse link
G Cnih2 cornichon family AMPA receptor auxiliary protein 2 part_of IDA PMID:19265014 MGI PMID:19265014 RGD:8554136 NCBI chr 1:202,399,416...202,405,110
Ensembl chr 1:202,399,419...202,405,089
JBrowse link
G Cnih3 cornichon family AMPA receptor auxiliary protein 3 part_of IDA PMID:19265014 UniProt PMID:19265014 RGD:8554136 NCBI chr13:93,016,707...93,208,168
Ensembl chr13:93,099,784...93,208,121
JBrowse link
G Cpt1c carnitine palmitoyltransferase 1c part_of ISO (MGI:5440375|PMID:22632720) RGD PMID:22632720 MGI:5440375 NCBI chr 1:95,442,814...95,457,347
Ensembl chr 1:95,442,817...95,457,342
JBrowse link
G Dlg3 discs large MAGUK scaffold protein 3 part_of ISO (MGI:5440375|PMID:22632720) RGD PMID:22632720 MGI:5440375 NCBI chr  X:65,859,653...65,911,887
Ensembl chr  X:65,860,172...65,910,322
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 part_of ISS
ISO
IEA
GO_REF:0000024
(MGI:3587474|PMID:15883194), (MGI:5440375|PMID:22632720)
GO_REF:0000107
BHF-UCL
RGD
Ensembl
PMID:15883194 PMID:22632720 GO_REF:0000024 GO_REF:0000107 MGI:3587474 MGI:5440375 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 part_of IEA
ISO
IDA
IBA
GO_REF:0000107
(MGI:3587474|PMID:15883194), (MGI:5440375|PMID:22632720)
PMID:19265014
PMID:21873635
Ensembl
RGD
PMID:15883194 PMID:22632720 PMID:19265014 PMID:21873635 GO_REF:0000107 MGI:3587474 MGI:5440375, RGD:8554136, RGD:13792537 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 part_of IDA
ISO
IBA
PMID:19946266
(MGI:3587474|PMID:15883194), (MGI:5440375|PMID:22632720)
PMID:21873635
PMID:19265014
RGD PMID:15883194 PMID:22632720 PMID:19946266 PMID:21873635 PMID:19265014 MGI:3587474 MGI:5440375, RGD:8553832, RGD:13792537, RGD:8554136 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 part_of IDA
ISO
IBA
PMID:19265014
(MGI:5440375|PMID:22632720)
PMID:21873635
RGD PMID:22632720 PMID:19265014 PMID:21873635 MGI:5440375, RGD:8554136, RGD:13792537 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096
JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 part_of IDA
ISO
IBA
PMID:19265014
(MGI:3587474|PMID:15883194), (MGI:5440375|PMID:22632720)
PMID:21873635
RGD PMID:15883194 PMID:22632720 PMID:19265014 PMID:21873635 MGI:3587474 MGI:5440375, RGD:8554136, RGD:13792537 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979
JBrowse link
G Lrrtm4 leucine rich repeat transmembrane neuronal 4 part_of ISO (MGI:5440375|PMID:22632720) RGD PMID:22632720 MGI:5440375 NCBI chr 4:112,545,874...113,338,713
Ensembl chr 4:112,545,917...113,335,865
JBrowse link
G Nrn1 neuritin 1 part_of ISO (MGI:5440375|PMID:22632720) RGD PMID:22632720 MGI:5440375 NCBI chr17:28,129,969...28,138,898
Ensembl chr17:28,129,977...28,138,896
JBrowse link
G Olfm1 olfactomedin 1 part_of ISO (MGI:5440375|PMID:22632720) RGD PMID:22632720 MGI:5440375 NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239
JBrowse link
G Olfm2 olfactomedin 2 part_of ISO (MGI:5440375|PMID:22632720) RGD PMID:22632720 MGI:5440375 NCBI chr 8:19,204,472...19,282,154
Ensembl chr 8:19,204,475...19,282,117
JBrowse link
G Olfm3 olfactomedin 3 part_of ISO (MGI:5440375|PMID:22632720) RGD PMID:22632720 MGI:5440375 NCBI chr 2:202,729,610...202,952,120
Ensembl chr 2:202,729,936...202,952,112
JBrowse link
G Porcn porcupine O-acyltransferase part_of ISO (MGI:5440375|PMID:22632720) RGD PMID:22632720 MGI:5440375 NCBI chr  X:14,285,864...14,298,481
Ensembl chr  X:14,285,871...14,298,481
JBrowse link
G Sacm1l SAC1 like phosphatidylinositide phosphatase part_of ISO (MGI:5440375|PMID:22632720) RGD PMID:22632720 MGI:5440375 NCBI chr 8:123,176,017...123,232,413
Ensembl chr 8:123,172,536...123,232,413
JBrowse link
G Shisa6 shisa family member 6 part_of IBA
ISO
PMID:21873635
(MGI:5440375|PMID:22632720)
RGD PMID:22632720 PMID:21873635 MGI:5440375, RGD:13792537 NCBI chr10:50,897,740...51,192,413
Ensembl chr10:50,903,333...51,192,063
JBrowse link
G Shisa7 shisa family member 7 part_of
NOT|part_of
IBA
ISO
PMID:21873635
(MGI:6377643|PMID:31601770)
RGD PMID:31601770 PMID:21873635 MGI:6377643, RGD:13792537 NCBI chr 1:68,993,900...69,012,943
Ensembl chr 1:68,994,025...69,012,943
JBrowse link
G Shisa8 shisa family member 8 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:113,722,408...113,727,858
Ensembl chr 7:113,722,408...113,727,858
JBrowse link
G Shisa9 shisa family member 9 part_of ISO (MGI:5440375|PMID:22632720) RGD PMID:22632720 MGI:5440375 NCBI chr10:3,335,616...3,629,334 JBrowse link
G Vwc2 von Willebrand factor C domain containing 2 part_of IBA
ISO
PMID:21873635
(MGI:5440375|PMID:22632720)
RGD PMID:22632720 PMID:21873635 MGI:5440375, RGD:13792537 NCBI chr14:85,683,670...85,825,068
Ensembl chr14:85,684,414...85,818,524
JBrowse link
G Vwc2l von Willebrand factor C domain containing 2 like part_of IBA
ISO
PMID:21873635
(MGI:5440375|PMID:22632720)
RGD PMID:22632720 PMID:21873635 MGI:5440375, RGD:13792537 NCBI chr 9:72,252,793...72,448,543
Ensembl chr 9:72,253,387...72,444,839
JBrowse link
kainate selective glutamate receptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 part_of IDA PMID:20107073 UniProt PMID:20107073 RGD:8554240 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 part_of ISO PR:P39087|PR:Q61626 (MGI:3717543|PMID:17174564) RGD PMID:17174564 MGI:3717543 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 part_of IBA
ISO
PMID:21873635
PR:Q60934|PR:Q61626|PR:Q8BMF5 (MGI:2674165|PMID:12954862), (MGI:3717543|PMID:17174564)
RGD PMID:12954862 PMID:17174564 PMID:21873635 MGI:2674165 MGI:3717543, RGD:13792537 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307
JBrowse link
G Grik4 glutamate ionotropic receptor kainate type subunit 4 part_of IEA
ISO
IBA
GO_REF:0000107
PR:P39087|PR:Q61626 (MGI:2674165|PMID:12954862)
PMID:21873635
Ensembl
RGD
PMID:12954862 PMID:21873635 GO_REF:0000107 MGI:2674165, RGD:13792537 NCBI chr 8:42,903,043...43,331,990
Ensembl chr 8:42,905,056...43,193,751
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 part_of ISO PR:P39087|PR:Q60934|PR:Q8BMF5 (MGI:2674165|PMID:12954862), (MGI:3717543|PMID:17174564) RGD PMID:12954862 PMID:17174564 MGI:2674165 MGI:3717543 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125
JBrowse link
NMDA selective glutamate receptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eps8 epidermal growth factor receptor pathway substrate 8 part_of ISO (MGI:3692803|PMID:17018287) RGD PMID:17018287 MGI:3692803 NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 part_of TAS
IEA
ISO
IDA
IBA
GO_REF:0000107
PR:P35436|PR:Q01097 (MGI:85255|PMID:9003035)
PMID:18177891
PMID:28384476
PMID:24876489
(PMID:10480938), (PMID:17047094), (PMID:26875626), (PMID:26919761), (PMID:28105280), (PMID:7679115)
PMID:21873635
Ensembl
RGD
PMID:7679115 PMID:9003035 PMID:10480938 PMID:17047094 PMID:26875626 More... GO_REF:0000107 MGI:85255, RGD:727495, RGD:13432252, RGD:13432313, RGD:13432263, RGD:13792537, RGD:7241301, RGD:1642380, RGD:1642190 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A part_of IDA
ISO
IBA
IEA
PR:P35438|UniProtKB:P35439 (MGI:68623|PMID:7929101), (MGI:85255|PMID:9003035)
PMID:21873635
GO_REF:0000107
PMID:28384476
PMID:8702950
(PMID:10480938), (PMID:26875626)
PMID:23625947
RGD
Ensembl
PMID:7929101 PMID:9003035 PMID:10480938 PMID:26875626 PMID:16477151 More... GO_REF:0000107 MGI:68623 MGI:85255, RGD:1642190, RGD:13792537, RGD:13432313, RGD:8553561, RGD:13432339, RGD:7241301 NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B part_of IDA
ISO
IEA
IBA
PR:P35438 (MGI:85255|PMID:9003035)
PMID:24876489
GO_REF:0000107
PMID:8702950
(PMID:10480938), (PMID:17047094), (PMID:26875626), (PMID:26919761)
PMID:28384476
PMID:21873635
RGD
Ensembl
PMID:9003035 PMID:10480938 PMID:17047094 PMID:26875626 PMID:26919761 More... GO_REF:0000107 MGI:85255, RGD:727540, RGD:13432263, RGD:8553561, RGD:13432313, RGD:13792537, RGD:1642190 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C part_of IDA
ISO
IEA
IBA
UniProtKB:P35439 (MGI:68623|PMID:7929101)
GO_REF:0000107
(PMID:26875626), (PMID:26919761)
PMID:21873635
RGD
Ensembl
PMID:7929101 PMID:26875626 PMID:26919761 PMID:16606616 PMID:21873635 GO_REF:0000107 MGI:68623, RGD:1642375, RGD:13792537 NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427
JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D part_of IDA
IEA
IBA
ISO
GO_REF:0000107
PMID:23625947
PMID:21873635
(PMID:26875626), (PMID:26919761)
Ensembl
RGD
PMID:26875626 PMID:26919761 PMID:17050728 PMID:23625947 PMID:21873635 GO_REF:0000107, RGD:1642380, RGD:13432339, RGD:13792537 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793
JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A part_of IDA
ISO
PMID:17182766
(PMID:17997397)
RGD PMID:17997397 PMID:16477151 PMID:17182766 RGD:1642190, RGD:8553928 NCBI chr 5:64,006,847...64,206,408
Ensembl chr 5:64,009,980...64,206,085
JBrowse link
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B part_of IDA
ISO
IEA
(MGI:3688366|PMID:14602821)
GO_REF:0000107
RGD
Ensembl
PMID:14602821 PMID:11823786 GO_REF:0000107 MGI:3688366, RGD:632842 NCBI chr 7:9,730,861...9,737,183
Ensembl chr 7:9,730,862...9,737,183
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta part_of IMP
IDA
PMID:15814199
PMID:11239437
Alzheimers_University_of_Toronto PMID:15814199 PMID:11239437 RGD:8655534, RGD:8553497 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19896
    protein-containing complex 5946
      transporter complex 413
        transmembrane transporter complex 398
          ion channel complex 297
            ionotropic glutamate receptor complex 45
              AMPA glutamate receptor complex 30
              NMDA selective glutamate receptor complex 9
              kainate selective glutamate receptor complex 6
Path 2
Term Annotations click to browse term
  cellular_component 19896
    cellular anatomical entity 19599
      membrane 9895
        plasma membrane 6164
          plasma membrane protein complex 555
            plasma membrane signaling receptor complex 171
              neurotransmitter receptor complex 47
                ionotropic glutamate receptor complex 45
                  AMPA glutamate receptor complex 30
                  NMDA selective glutamate receptor complex 9
                  kainate selective glutamate receptor complex 6
paths to the root