ONTOLOGY REPORT - ANNOTATIONS
Term: isoprenoid biosynthetic process
Accession: GO:0008299
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Definition: The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
Synonyms: exact_synonym: isoprenoid anabolism; isoprenoid biosynthesis; isoprenoid formation; isoprenoid synthesis
narrow_synonym: polyisoprenoid anabolism; polyisoprenoid biosynthesis; polyisoprenoid biosynthetic process; polyisoprenoid formation; polyisoprenoid synthesis; polyterpene biosynthesis; polyterpene biosynthetic process
alt_id: GO:0009241
xref: MetaCyc:POLYISOPRENSYN-PWY
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Coq2
coenzyme Q2, polyprenyltransferase
involved_in
IEA
GO_REF:0000104
UniProt
GO_REF:0000104
NCBI chr14:8,941,429...8,961,418
Ensembl chr14:8,941,461...8,960,891
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Crppa
CDP-L-ribitol pyrophosphorylase A
involved_in
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 6:53,120,264...53,397,030
Ensembl chr 6:53,121,438...53,397,028
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ENSRNOG00000062441
involved_in
IEA
GO_REF:0000043
UniProt
GO_REF:0000043
Ensembl chr17:61,602,519...61,608,185
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Fdft1
farnesyl diphosphate farnesyl transferase 1
involved_in
IEA
GO_REF:0000043
UniProt
GO_REF:0000043
NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
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Fdps
farnesyl diphosphate synthase
involved_in
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
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Ggps1
geranylgeranyl diphosphate synthase 1
involved_in
IEA IBA
GO_REF:0000043 GO_REF:0000033
UniProt GO_Central
GO_REF:0000033 GO_REF:0000043
NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
involved_in
IEA IBA
GO_REF:0000002 GO_REF:0000033
InterPro GO_Central
GO_REF:0000002 GO_REF:0000033
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Idi1
isopentenyl-diphosphate delta isomerase 1
involved_in
ISO IEA
(PMID:8806705) GO_REF:0000043
RGD UniProt
PMID:8806705
GO_REF:0000043
NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
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Idi2
isopentenyl-diphosphate delta isomerase 2
involved_in
ISO
(PMID:17202134)
RGD
PMID:17202134
NCBI chr17:61,331,385...61,334,987
Ensembl chr17:61,331,669...61,334,285
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LOC120097764
isopentenyl-diphosphate delta-isomerase 2-like
involved_in
IEA
GO_REF:0000043
UniProt
GO_REF:0000043
NCBI chr17:61,338,622...61,349,795
Ensembl chr17:61,347,251...61,349,795 Ensembl chr17:61,347,251...61,349,795
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Mvd
mevalonate diphosphate decarboxylase
involved_in
ISO
(PMID:11792727), (PMID:14680974)
RGD
PMID:11792727 PMID:14680974
NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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Mvk
mevalonate kinase
involved_in
IDA ISO
(PMID:14680974), (PMID:14730012)
RGD
PMID:14680974 PMID:14730012 PMID:7904598
RGD:2316851
NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
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Pdss1
decaprenyl diphosphate synthase subunit 1
involved_in
ISO IBA
(PMID:16262699) GO_REF:0000033
RGD GO_Central
PMID:16262699
GO_REF:0000033
NCBI chr17:85,059,953...85,098,739
Ensembl chr17:85,060,106...85,098,730
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Pdss2
decaprenyl diphosphate synthase subunit 2
involved_in
ISO IBA IEA
(PMID:16262699) GO_REF:0000033 GO_REF:0000043
RGD GO_Central UniProt
PMID:16262699
GO_REF:0000033 GO_REF:0000043
NCBI chr20:46,709,631...46,938,704
Ensembl chr20:46,709,649...46,938,708
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Pex5
peroxisomal biogenesis factor 5
NOT|acts_upstream_of_or_within
ISO
MGI:2154454 (PMID:11420171)
RGD
PMID:11420171
NCBI chr 4:157,270,671...157,296,432
Ensembl chr 4:157,270,672...157,296,431
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Rusc1
RUN and SH3 domain containing 1
involved_in
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 2:174,487,921...174,497,266
Ensembl chr 2:174,486,665...174,507,776
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (PMID:11876656)
Ensembl RGD
PMID:11876656
GO_REF:0000107
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Aldh1a2
aldehyde dehydrogenase 1 family, member A2
acts_upstream_of_or_within
ISO
(PMID:11876656)
RGD
PMID:11876656
NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
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Aldh8a1
aldehyde dehydrogenase 8 family, member A1
acts_upstream_of_or_within
ISO
(PMID:11876656)
RGD
PMID:11876656
NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
IDA
9-cis- and all-trans-retinoic acid synthesized from 9-cis- and all-trans-retinal
RGD
PMID:8765131
RGD:2306683
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Dhrs9
dehydrogenase/reductase 9
involved_in
ISO ISS
(PMID:11304534) GO_REF:0000024
RGD UniProt
PMID:11304534
GO_REF:0000024
NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241
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Rdh9
retinol dehydrogenase 9
acts_upstream_of_or_within
ISO
(PMID:11876656)
RGD
PMID:11876656
NCBI chr 7:63,642,305...63,645,149
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Acat2
acetyl-CoA acetyltransferase 2
involved_in
TAS
PMID:10806397
UniProt
PMID:10806397
RGD:2326086
NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Dhdds
dehydrodolichyl diphosphate synthase subunit
involved_in
ISO
(PMID:28842490)
RGD
PMID:28842490
NCBI chr 5:146,198,359...146,224,479
Ensembl chr 5:146,197,457...146,224,454
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Dhrsx
dehydrogenase/reductase X-linked
involved_in
ISO
(PMID:38821050)
RGD
PMID:38821050
NCBI chr12:16,299,768...16,304,553
Ensembl chr12:16,299,808...16,304,552
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Nus1
NUS1 dehydrodolichyl diphosphate synthase subunit
acts_upstream_of_or_within involved_in
ISO IBA
(PMID:25066056) GO_REF:0000033
RGD GO_Central
PMID:25066056
GO_REF:0000033
NCBI chr20:31,811,817...31,838,562
Ensembl chr20:31,811,817...31,838,561
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Srd5a3
steroid 5 alpha-reductase 3
involved_in
IBA ISS IEA ISO
GO_REF:0000033 GO_REF:0000024 GO_REF:0000107 (PMID:38821050)
GO_Central UniProt Ensembl RGD
PMID:38821050
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107
NCBI chr14:32,046,408...32,060,796
Ensembl chr14:32,046,408...32,060,747
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Fdps
farnesyl diphosphate synthase
involved_in
IDA IBA IEA
GO_REF:0000033 GO_REF:0000041
GO_Central UniProt RGD
PMID:8188698
GO_REF:0000033 GO_REF:0000041, RGD:2316305
NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
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Ggps1
geranylgeranyl diphosphate synthase 1
involved_in
IEA
GO_REF:0000041
UniProt
GO_REF:0000041
NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220
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Hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1
involved_in
IEA IBA
GO_REF:0000002 GO_REF:0000033
InterPro GO_Central
GO_REF:0000002 GO_REF:0000033
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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Hmgcs2
3-hydroxy-3-methylglutaryl-CoA synthase 2
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
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Fdps
farnesyl diphosphate synthase
involved_in
IEA
GO_REF:0000041
UniProt
GO_REF:0000041
NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
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Ggps1
geranylgeranyl diphosphate synthase 1
involved_in
IEA
GO_REF:0000041
UniProt
GO_REF:0000041
NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220
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Ggps1
geranylgeranyl diphosphate synthase 1
involved_in
IEA
GO_REF:0000041
UniProt
GO_REF:0000041
NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220
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Idi1
isopentenyl-diphosphate delta isomerase 1
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
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Idi2
isopentenyl-diphosphate delta isomerase 2
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr17:61,331,385...61,334,987
Ensembl chr17:61,331,669...61,334,285
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Idi2l2
isopentenyl-diphosphate delta isomerase 2 like 2
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr17:61,372,853...61,386,459
Ensembl chr17:61,373,678...61,386,454
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Idi2l3
isopentenyl-diphosphate delta isomerase 2 like 3
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr17:61,518,138...61,535,484
Ensembl chr17:61,519,390...61,531,603
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LOC102551575
isopentenyl-diphosphate delta-isomerase 2-like
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr17:61,504,294...61,507,015
Ensembl chr17:61,504,535...61,507,015
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Mvd
mevalonate diphosphate decarboxylase
involved_in
IDA IBA IEA
GO_REF:0000033 GO_REF:0000104 GO_REF:0000002
GO_Central UniProt InterPro RGD
PMID:197206
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104, RGD:2316852
NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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Mvk
mevalonate kinase
involved_in
IDA IBA IEA
GO_REF:0000033 GO_REF:0000041
GO_Central UniProt RGD
PMID:197206
GO_REF:0000033 GO_REF:0000041, RGD:2316852
NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
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Pmvk
phosphomevalonate kinase
involved_in
IDA IBA IEA
GO_REF:0000033 GO_REF:0000041
GO_Central UniProt RGD
PMID:197206
GO_REF:0000033 GO_REF:0000041, RGD:2316852
NCBI chr 2:174,876,586...174,886,365
Ensembl chr 2:174,876,657...174,886,364
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Akr1c3
aldo-keto reductase family 1, member C3
involved_in
ISO
(PMID:21851338)
RGD
PMID:21851338
NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
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Prmt3
protein arginine methyltransferase 3
involved_in
ISO IEA ISS
(PMID:33495566) GO_REF:0000107 GO_REF:0000024
RGD Ensembl UniProt
PMID:33495566
GO_REF:0000024 GO_REF:0000107
NCBI chr 1:99,492,712...99,581,774
Ensembl chr 1:99,492,724...99,579,435
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Dhdds
dehydrodolichyl diphosphate synthase subunit
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 5:146,198,359...146,224,479
Ensembl chr 5:146,197,457...146,224,454
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Rdh10
retinol dehydrogenase 10
IMP
RGD
PMID:21138835
RGD:6771354
NCBI chr 5:3,186,671...3,215,572
Ensembl chr 5:3,188,445...3,215,572
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Rdh16
retinol dehydrogenase 16
IMP
RGD
PMID:21138835
RGD:6771354
NCBI chr 7:63,616,711...63,625,053
Ensembl chr 7:63,597,536...63,624,124
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
IMP
RGD
PMID:21138835
RGD:6771354
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Aldh1a2
aldehyde dehydrogenase 1 family, member A2
involved_in
IEP ISO ISS IMP
(PMID:29240402), (PMID:33565183) GO_REF:0000024
RGD UniProt
PMID:29240402 PMID:33565183 PMID:15950969 PMID:21138835
GO_REF:0000024, RGD:6771322 , RGD:6771354
NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
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Aldh1a3
aldehyde dehydrogenase 1 family, member A3
involved_in acts_upstream_of_or_within
IEP ISO ISS IEA IMP
(PMID:14623956) (PMID:11013254), (PMID:11044606), (PMID:16241904) (PMID:27759097) GO_REF:0000024 GO_REF:0000107
RGD UniProt Ensembl
PMID:11013254 PMID:11044606 PMID:14623956 PMID:16241904 PMID:27759097 PMID:15950969 PMID:21138835 More...
GO_REF:0000024 GO_REF:0000107, RGD:6771322 , RGD:6771354
NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
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Crabp2
cellular retinoic acid binding protein 2
IEP
RGD
PMID:15950969
RGD:6771322
NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
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Dhrs9
dehydrogenase/reductase 9
IEP IDA
RGD
PMID:15950969 PMID:21138835
RGD:6771322 , RGD:6771354
NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241
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Rbp1
retinol binding protein 1
IEP
RGD
PMID:15950969
RGD:6771322
NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
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Rdh10
retinol dehydrogenase 10
acts_upstream_of_or_within
ISO
(PMID:17473173)
RGD
PMID:17473173
NCBI chr 5:3,186,671...3,215,572
Ensembl chr 5:3,188,445...3,215,572
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Lss
lanosterol synthase
involved_in
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
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Rpe65
retinoid isomerohydrolase RPE65
involved_in
ISO ISS IBA
(PMID:28874556) GO_REF:0000024 GO_REF:0000033
RGD UniProt GO_Central
PMID:28874556
GO_REF:0000024 GO_REF:0000033
NCBI chr 2:248,766,497...248,798,403
Ensembl chr 2:248,766,612...248,798,403
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