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ONTOLOGY REPORT - ANNOTATIONS

Term:calcium- and calmodulin-responsive adenylate cyclase activity
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Accession:GO:0008294 term browser browse the term
Definition:Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate, stimulated by calcium-bound calmodulin.
Synonyms:exact_synonym: calcium- and calmodulin-responsive adenylyl cyclase activity;   calcium/calmodulin-responsive adenylate cyclase activity
 xref: reactome:R-HSA-111930 "Adenylate cyclase produces cAMP";   reactome:R-HSA-442715 "Calmodulin-activated adenylate cyclases ADCY1 and ADCY8 generate cAMP"


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calcium- and calmodulin-responsive adenylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY1 adenylate cyclase 1 ISO RGD PMID:14985420 RGD:2312640 NCBI chr18:50,043,572...50,143,549
Ensembl chr18:50,051,364...50,143,628 		JBrowse link
G ADCY3 adenylate cyclase 3 ISO RGD PMID:12711600 RGD:2312674 NCBI chr 3:113,875,005...113,969,053
Ensembl chr 3:113,876,339...113,982,369 		JBrowse link
G ADCY5 adenylate cyclase 5 ISO RGD PMID:10894801 RGD:2315006 NCBI chr13:136,965,746...137,133,795
Ensembl chr13:136,972,801...137,135,347 		JBrowse link
G ADCY6 adenylate cyclase 6 enables ISO (PMID:1379717) RGD
MGI		 PMID:1379717 PMID:10894801 RGD:2315006 NCBI chr 5:14,834,420...14,855,309
Ensembl chr 5:14,834,426...14,850,728 		JBrowse link
G ADCY8 adenylate cyclase 8 enables ISO
IEA		 RGD
Ensembl		 PMID:8163524 GO_REF:0000107 RGD:69741 NCBI chr 4:9,645,398...9,867,065
Ensembl chr 4:9,645,659...9,866,550 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18714
    catalytic activity 5686
      cyclase activity 25
        adenylate cyclase activity 19
          calcium- and calmodulin-responsive adenylate cyclase activity 5
Path 2
Term Annotations click to browse term
  molecular_function 18714
    catalytic activity 5686
      lyase activity 204
        phosphorus-oxygen lyase activity 27
          adenylate cyclase activity 19
            calcium- and calmodulin-responsive adenylate cyclase activity 5
paths to the root