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ONTOLOGY REPORT - ANNOTATIONS


Term:acetylcholine metabolic process
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Accession:GO:0008291 term browser browse the term
Definition:The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
Synonyms:exact_synonym: acetylcholine metabolism



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acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase ISO RGD PMID:16628397 RGD:1580871 NCBI chr 3:8,732,451...8,738,274
Ensembl chr 3:8,732,441...8,738,605
JBrowse link
acetylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHAT choline O-acetyltransferase involved_in ISO
IBA
IEA
RGD
GO_Central
TreeGrafter
PMID:126256 PMID:334962 PMID:4008917 PMID:6854006 GO_REF:0000033 GO_REF:0000118 RGD:2301195 RGD:2301197 RGD:2301199 RGD:2301203 NCBI chr14:90,117,464...90,167,611
Ensembl chr14:90,117,464...90,167,611
JBrowse link
G SLC44A4 solute carrier family 44 member 4 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:23,958,935...23,977,466
Ensembl chr 7:23,958,942...23,977,482
JBrowse link
G SLC5A7 solute carrier family 5 member 7 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3044863|PMID:15173594) MGI
TreeGrafter
Ensembl
PMID:15173594 GO_REF:0000107 GO_REF:0000118 MGI:3044863 NCBI chr 3:47,994,116...48,020,744
Ensembl chr 3:47,996,335...48,022,379
JBrowse link
acetylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase involved_in
acts_upstream_of_or_within
ISO
IEA
IBA
(MGI:3654414|PMID:16434405), (MGI:65815|PMID:7512968) RGD
TreeGrafter
GO_Central
Ensembl
MGI
PMID:126256 PMID:334962 PMID:1133098 PMID:2731551 PMID:3655326 More... GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:3654414 MGI:65815 RGD:1580870 RGD:2301187 RGD:2301195 RGD:2301197 RGD:2301199 RGD:2301203 RGD:2301204 RGD:2301205 RGD:2301207 RGD:2301213 NCBI chr 3:8,732,451...8,738,274
Ensembl chr 3:8,732,441...8,738,605
JBrowse link
G BCHE butyrylcholinesterase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:104,946,732...105,007,568 JBrowse link
positive regulation of acetylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PEBP1 phosphatidylethanolamine binding protein 1 ISO RGD PMID:10622376 RGD:2302808 NCBI chr14:34,523,901...34,530,238 JBrowse link
positive regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PEBP1 phosphatidylethanolamine binding protein 1 ISO RGD PMID:8888012 RGD:2302806 NCBI chr14:34,523,901...34,530,238 JBrowse link
regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FSHR follicle stimulating hormone receptor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3628883|PMID:12204217) MGI
Ensembl
PMID:12204217 GO_REF:0000107 MGI:3628883 NCBI chr 3:91,607,236...91,775,255
Ensembl chr 3:91,607,305...91,774,683
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17816
    metabolic process 10350
      nitrogen compound metabolic process 8468
        acetylcholine metabolic process 7
          acetylcholine biosynthetic process + 4
          acetylcholine catabolic process + 2
          negative regulation of acetylcholine metabolic process + 0
          positive regulation of acetylcholine metabolic process + 1
          regulation of acetylcholine metabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 17816
    metabolic process 10350
      organic substance metabolic process 9914
        acetate ester metabolic process 7
          acetylcholine metabolic process 7
            acetylcholine biosynthetic process + 4
            acetylcholine catabolic process + 2
            negative regulation of acetylcholine metabolic process + 0
            positive regulation of acetylcholine metabolic process + 1
            regulation of acetylcholine metabolic process + 2
paths to the root