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ONTOLOGY REPORT - ANNOTATIONS


Term:acetylcholine metabolic process
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Accession:GO:0008291 term browser browse the term
Definition:The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
Synonyms:exact_synonym: acetylcholine metabolism



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acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in ISO RGD
MGI
PMID:16628397 GO_REF:0000096 MGI:4417868 RGD:1580871 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
acetylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chat choline acetyltransferase involved_in ISO
IBA
(MGI:6201960|PMID:21873635) RGD
GO_Central
MGI
PMID:126256 PMID:334962 PMID:4008917 PMID:6854006 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:6201960 RGD:2301195 RGD:2301197 RGD:2301199 RGD:2301203 NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946
JBrowse link
G Slc44a4 solute carrier family 44, member 4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:35,133,200...35,149,412
Ensembl chr17:35,133,442...35,149,412
JBrowse link
G Slc5a7 solute carrier family 5 (choline transporter), member 7 acts_upstream_of_or_within
involved_in
IMP
IBA
ISO
IDA
(MGI:3044863|PMID:15173594)
(MGI:6201960|PMID:21873635)
(MGI:7510309|PMID:11709061)
MGI
GO_Central
UniProt
PMID:11709061 PMID:15173594 PMID:21873635 GO_REF:0000096 GO_REF:0000119 MGI:3044863 MGI:4417868 MGI:4834177 MGI:6201960 MGI:7510309 NCBI chr17:54,580,618...54,606,071
Ensembl chr17:54,580,618...54,606,062
JBrowse link
acetylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase acts_upstream_of_or_within
involved_in
IDA
IBA
ISO
(MGI:3654414|PMID:16434405), (MGI:65815|PMID:7512968)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
RGD
PMID:126256 PMID:334962 PMID:1133098 PMID:2731551 PMID:3655326 More... GO_REF:0000096 GO_REF:0000119 MGI:3654414 MGI:4417868 MGI:4834177 MGI:6201960 MGI:65815 RGD:1580870 RGD:2301187 RGD:2301195 RGD:2301197 RGD:2301199 RGD:2301203 RGD:2301204 RGD:2301205 RGD:2301207 RGD:2301213 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Bche butyrylcholinesterase involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748
JBrowse link
positive regulation of acetylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pebp1 phosphatidylethanolamine binding protein 1 involved_in ISO RGD
MGI
PMID:10622376 GO_REF:0000096 MGI:4417868 RGD:2302808 NCBI chr 5:117,420,716...117,425,629
Ensembl chr 5:117,420,719...117,425,690
JBrowse link
positive regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pebp1 phosphatidylethanolamine binding protein 1 involved_in ISO RGD
MGI
PMID:8888012 GO_REF:0000096 MGI:4417868 RGD:2302806 NCBI chr 5:117,420,716...117,425,629
Ensembl chr 5:117,420,719...117,425,690
JBrowse link
regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fshr follicle stimulating hormone receptor acts_upstream_of_or_within IGI (MGI:3628883|PMID:12204217) MGI PMID:12204217 MGI:3628883 NCBI chr17:89,292,380...89,508,103
Ensembl chr17:89,292,380...89,508,103
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28562
    metabolic process 10993
      nitrogen compound metabolic process 8879
        acetylcholine metabolic process 7
          acetylcholine biosynthetic process + 4
          acetylcholine catabolic process + 2
          negative regulation of acetylcholine metabolic process + 0
          positive regulation of acetylcholine metabolic process + 1
          regulation of acetylcholine metabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 28562
    metabolic process 10993
      organic substance metabolic process 10561
        acetate ester metabolic process 7
          acetylcholine metabolic process 7
            acetylcholine biosynthetic process + 4
            acetylcholine catabolic process + 2
            negative regulation of acetylcholine metabolic process + 0
            positive regulation of acetylcholine metabolic process + 1
            regulation of acetylcholine metabolic process + 2
paths to the root