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ONTOLOGY REPORT - ANNOTATIONS


Term:acetylcholine metabolic process
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Accession:GO:0008291 term browser browse the term
Definition:The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
Synonyms:exact_synonym: acetylcholine metabolism



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acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase ISO RGD PMID:16628397 RGD:1580871 NCBI chr 6:8,874,747...8,879,926
Ensembl chr 6:8,873,584...8,879,702
JBrowse link
acetylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHAT choline O-acetyltransferase involved_in ISO
IEA
RGD
TreeGrafter
PMID:126256 PMID:334962 PMID:4008917 PMID:6854006 GO_REF:0000118 RGD:2301195 RGD:2301197 RGD:2301199 RGD:2301203 NCBI chr28:1,480,364...1,528,858
Ensembl chr28:1,482,202...1,528,776
JBrowse link
G SLC44A4 solute carrier family 44 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,328,276...1,340,752
Ensembl chr12:1,328,399...1,340,778
JBrowse link
G SLC5A7 solute carrier family 5 member 7 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15173594) Ensembl
MGI
TreeGrafter
PMID:15173594 GO_REF:0000107 GO_REF:0000118 NCBI chr10:35,879,880...35,908,203
Ensembl chr10:35,883,245...35,908,569
JBrowse link
acetylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:16434405), (PMID:7512968) RGD
MGI
TreeGrafter
Ensembl
PMID:126256 PMID:334962 PMID:1133098 PMID:2731551 PMID:3655326 More... GO_REF:0000107 GO_REF:0000118 RGD:1580870 RGD:2301187 RGD:2301195 RGD:2301197 RGD:2301199 RGD:2301203 RGD:2301204 RGD:2301205 RGD:2301207 RGD:2301213 NCBI chr 6:8,874,747...8,879,926
Ensembl chr 6:8,873,584...8,879,702
JBrowse link
G BCHE butyrylcholinesterase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr34:30,912,632...30,977,624
Ensembl chr34:30,912,632...30,977,583
JBrowse link
positive regulation of acetylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PEBP1 phosphatidylethanolamine binding protein 1 ISO RGD PMID:10622376 RGD:2302808 NCBI chr26:14,522,124...14,526,370
Ensembl chr26:14,500,074...14,529,354
JBrowse link
positive regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PEBP1 phosphatidylethanolamine binding protein 1 ISO RGD PMID:8888012 RGD:2302806 NCBI chr26:14,522,124...14,526,370
Ensembl chr26:14,500,074...14,529,354
JBrowse link
regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FSHR follicle stimulating hormone receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12204217) Ensembl
MGI
PMID:12204217 GO_REF:0000107 NCBI chr10:50,765,591...50,938,643
Ensembl chr10:50,770,995...50,938,474
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    metabolic process 10998
      organic substance metabolic process 10554
        acetate ester metabolic process 7
          acetylcholine metabolic process 7
            acetylcholine biosynthetic process + 4
            acetylcholine catabolic process + 2
            negative regulation of acetylcholine metabolic process + 0
            positive regulation of acetylcholine metabolic process + 1
            regulation of acetylcholine metabolic process + 2
paths to the root