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ONTOLOGY REPORT - ANNOTATIONS

Term:acetylcholine metabolic process
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Accession:GO:0008291 term browser browse the term
Definition:The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
Synonyms:exact_synonym: acetylcholine metabolism


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acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase IMP RGD PMID:16628397 RGD:1580871 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
acetylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chat choline O-acetyltransferase involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:126256 PMID:21873635 PMID:4008917 PMID:6854006 PMID:334962 RGD:2301195, RGD:13792537, RGD:2301203, RGD:2301199, RGD:2301197 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Slc44a4 solute carrier family 44, member 4 involved_in ISO
ISS		 (PMID:23651124), (PMID:28013291)
GO_REF:0000024		 RGD
UniProt		 PMID:23651124 PMID:28013291 GO_REF:0000024 NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215 		JBrowse link
G Slc5a7 solute carrier family 5 member 7 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS
IMP
IBA		 GO_REF:0000107
(MGI:7510309|PMID:11709061)
MGI:3045463 (MGI:3044863|PMID:15173594)
GO_REF:0000024
(PMID:11027560), (PMID:11068039)
PMID:10649566
PMID:21873635		 Ensembl
RGD
UniProt		 PMID:11027560 PMID:11068039 PMID:11709061 PMID:15173594 PMID:10649566 More... GO_REF:0000024 GO_REF:0000107 MGI:3044863 MGI:7510309, RGD:68853, RGD:13792537 NCBI chr 9:7,595,440...7,626,258
Ensembl chr 9:7,595,444...7,626,258 		JBrowse link
acetylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in
acts_upstream_of_or_within		 IDA
IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(MGI:3654414|PMID:16434405), (MGI:65815|PMID:7512968)
(PMID:1517212)		 Ensembl
RGD		 PMID:1517212 PMID:7512968 PMID:16434405 PMID:16052514 PMID:21873635 More... GO_REF:0000107 MGI:3654414 MGI:65815, RGD:1580870, RGD:13792537, RGD:2301213, RGD:2301207, RGD:2301205, RGD:2301204, RGD:2301203, RGD:2301199, RGD:2301197, RGD:2301195, RGD:2301187 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Bche butyrylcholinesterase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
acetylcholine catabolic process in synaptic cleft term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in IC PMID:26820598 SynGO PMID:26820598 RGD:12050110 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
positive regulation of acetylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pebp1 phosphatidylethanolamine binding protein 1 IDA RGD PMID:10622376 RGD:2302808 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862 		JBrowse link
positive regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pebp1 phosphatidylethanolamine binding protein 1 IDA RGD PMID:8888012 RGD:2302806 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862 		JBrowse link
regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fshr follicle stimulating hormone receptor acts_upstream_of_or_within ISO MGI:88392 (MGI:3628883|PMID:12204217) RGD PMID:12204217 MGI:3628883 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    metabolic process 11538
      organic substance metabolic process 10895
        acetate ester metabolic process 7
          acetylcholine metabolic process 7
            acetylcholine biosynthetic process + 4
            acetylcholine catabolic process + 2
            negative regulation of acetylcholine metabolic process + 0
            positive regulation of acetylcholine metabolic process + 1
            regulation of acetylcholine metabolic process + 2
paths to the root