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ONTOLOGY REPORT - ANNOTATIONS


Term:acetylcholine metabolic process
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Accession:GO:0008291 term browser browse the term
Definition:The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
Synonyms:exact_synonym: acetylcholine metabolism



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acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase IMP RGD PMID:16628397 RGD:1580871 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651
JBrowse link
acetylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chat choline O-acetyltransferase involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:126256 PMID:6854006 PMID:4008917 PMID:334962 GO_REF:0000033, RGD:2301195, RGD:2301199, RGD:2301203, RGD:2301197 NCBI chr16:7,663,665...7,723,416
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Slc44a4 solute carrier family 44, member 4 involved_in ISS
ISO
GO_REF:0000024
(PMID:23651124), (PMID:28013291)
UniProt
RGD
PMID:23651124 PMID:28013291 GO_REF:0000024 NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215
JBrowse link
G Slc5a7 solute carrier family 5 member 7 involved_in
acts_upstream_of_or_within
ISO
IBA
ISS
IEA
IMP
(PMID:11709061), (PMID:15173594)
MGI:3045463 (PMID:15173594)
GO_REF:0000033
GO_REF:0000024
(PMID:11027560), (PMID:11068039)
GO_REF:0000107
PMID:10649566
RGD
GO_Central
UniProt
Ensembl
PMID:11027560 PMID:11068039 PMID:11709061 PMID:15173594 PMID:10649566 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:68853 NCBI chr 9:7,922,693...7,953,509
Ensembl chr 9:7,595,444...7,626,258
JBrowse link
acetylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
IEA
(PMID:16434405), (PMID:7512968)
GO_REF:0000033
GO_REF:0000107
(PMID:1517212)
RGD
GO_Central
Ensembl
PMID:1517212 PMID:7512968 PMID:16434405 PMID:8737018 PMID:14646156 More... GO_REF:0000033 GO_REF:0000107, RGD:2301207, RGD:2301213, RGD:2301204, RGD:2301205, RGD:2301203, RGD:2301199, RGD:2301197, RGD:2301195, RGD:1580870 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Bche butyrylcholinesterase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
positive regulation of acetylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pebp1 phosphatidylethanolamine binding protein 1 IDA RGD PMID:10622376 RGD:2302808 NCBI chr12:44,946,307...44,967,890
Ensembl chr12:39,302,840...39,307,862
JBrowse link
positive regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pebp1 phosphatidylethanolamine binding protein 1 IDA RGD PMID:8888012 RGD:2302806 NCBI chr12:44,946,307...44,967,890
Ensembl chr12:39,302,840...39,307,862
JBrowse link
regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fshr follicle stimulating hormone receptor acts_upstream_of_or_within ISO MGI:88392 (PMID:12204217) RGD PMID:12204217 NCBI chr 6:10,952,329...11,160,288
Ensembl chr 6:5,198,825...5,406,785
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    cellular process 19525
      metabolic process 12160
        acetate ester metabolic process 7
          acetylcholine metabolic process 7
            acetylcholine biosynthetic process + 4
            acetylcholine catabolic process + 2
            negative regulation of acetylcholine metabolic process + 0
            positive regulation of acetylcholine metabolic process + 1
            regulation of acetylcholine metabolic process + 2
paths to the root