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ONTOLOGY REPORT - ANNOTATIONS


Term:acetylcholine metabolic process
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Accession:GO:0008291 term browser browse the term
Definition:The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
Synonyms:exact_synonym: acetylcholine metabolism



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acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase IMP RGD PMID:16628397 RGD:1580871 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
acetylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chat choline O-acetyltransferase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:126256 PMID:21873635 PMID:334962 PMID:6854006 PMID:4008917 RGD:2301195, RGD:13792537, RGD:2301197, RGD:2301199, RGD:2301203 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Slc44a4 solute carrier family 44, member 4 involved_in ISO
ISS
(PMID:23651124), (PMID:28013291)
GO_REF:0000024
RGD
UniProt
PMID:23651124 PMID:28013291 GO_REF:0000024 NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215
JBrowse link
G Slc5a7 solute carrier family 5 member 7 involved_in
acts_upstream_of_or_within
IEA
ISO
IMP
IBA
GO_REF:0000107
MGI:3045463 (MGI:3044863|PMID:15173594)
PMID:10649566
(PMID:11068039)
PMID:21873635
Ensembl
RGD
PMID:11068039 PMID:15173594 PMID:10649566 PMID:21873635 GO_REF:0000107 MGI:3044863, RGD:68853, RGD:13792537 NCBI chr 9:7,595,440...7,626,258
Ensembl chr 9:7,595,444...7,626,258
JBrowse link
acetylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in
acts_upstream_of_or_within
IDA
IEA
ISO
GO_REF:0000107
(MGI:3654414|PMID:16434405), (MGI:65815|PMID:7512968)
(PMID:1517212)
Ensembl
RGD
PMID:1517212 PMID:7512968 PMID:16434405 PMID:16052514 PMID:14646156 More... GO_REF:0000107 MGI:3654414 MGI:65815, RGD:1580870, RGD:2301213, RGD:2301207, RGD:2301205, RGD:2301204, RGD:2301203, RGD:2301199, RGD:2301197, RGD:2301195, RGD:2301187 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
acetylcholine catabolic process in synaptic cleft term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase involved_in IC PMID:26820598 SynGO PMID:26820598 RGD:12050110 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
positive regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pebp1 phosphatidylethanolamine binding protein 1 IDA RGD PMID:8888012 RGD:2302806 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fshr follicle stimulating hormone receptor acts_upstream_of_or_within ISO MGI:88392 (MGI:3628883|PMID:12204217) RGD PMID:12204217 MGI:3628883 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      nitrogen compound metabolic process 9922
        acetylcholine metabolic process 6
          acetylcholine biosynthetic process + 3
          acetylcholine catabolic process + 1
          negative regulation of acetylcholine metabolic process + 0
          positive regulation of acetylcholine metabolic process + 1
          regulation of acetylcholine metabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 19390
    biological regulation 13476
      regulation of biological quality 4152
        regulation of neurotransmitter levels 277
          neurotransmitter metabolic process 29
            acetylcholine metabolic process 6
              acetylcholine biosynthetic process + 3
              acetylcholine catabolic process + 1
              negative regulation of acetylcholine metabolic process + 0
              positive regulation of acetylcholine metabolic process + 1
              regulation of acetylcholine metabolic process + 2
paths to the root