Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:inward rectifying potassium channel
go back to main search page
Accession:GO:0008282 term browser browse the term
Definition:A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.x subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SURx subunit stimulates channel activity.
Synonyms:exact_synonym: ATP-sensitive potassium channel complex;   inward rectifying K+ channel
 related_synonym: KCNJ11-SUR complex;   KCNJ11-SURx complex;   KCNJ8-SUR complex;   KCNJ8-SURx complex;   Kir6-SUR complex;   Kir6.1-SUR complex;   Kir6.1-SURx complex;   Kir6.2-SUR complex;   Kir6.2-SURx complex;   Kir6.x complex;   Kir6.x-SURx complex


show annotations for term's descendants           Sort by:
 
inward rectifying potassium channel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 part_of IDA
ISO
(PMID:20610380) RGD PMID:20610380, PMID:24114458 RGD:10003028 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 part_of TAS
IDA
ISO
IEA
PMID:8630239
(PMID:20610380)
GO_REF:0000107
RGD
Ensembl
PMID:20610380, PMID:11967023, PMID:8630239 GO_REF:0000107, RGD:728123, RGD:8554593 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
JBrowse link
G Abcc9_v1 ATP binding cassette subfamily C member 9, variant 1 part_of IDA PMID:8630239 BHF-UCL PMID:8630239 RGD:8554593
G Abcc9_v2 ATP binding cassette subfamily C member 9, variant 2 part_of IDA PMID:8630239 BHF-UCL PMID:8630239 RGD:8554593
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 part_of IDA
ISO
(MGI:3793935|PMID:8630239)
(PMID:19805355), (PMID:20610380)
RGD PMID:8630239 PMID:19805355 PMID:20610380, PMID:17097686 MGI:3793935, RGD:1625274 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 IDA RGD PMID:17097686 RGD:1625274 NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20126
    protein-containing complex 6038
      membrane protein complex 1243
        plasma membrane protein complex 564
          inward rectifying potassium channel 6
Path 2
Term Annotations click to browse term
  cellular_component 20126
    cellular anatomical entity 19825
      membrane 10001
        intrinsic component of membrane 6769
          integral component of membrane 6627
            transmembrane transporter complex 329
              ion channel complex 309
                cation channel complex 235
                  potassium channel complex 101
                    inward rectifying potassium channel 6
paths to the root