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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of G protein-coupled receptor signaling pathway
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Accession:GO:0008277 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway.
Synonyms:exact_synonym: regulation of G protein coupled receptor protein signaling pathway;   regulation of G protein coupled receptor protein signalling pathway;   regulation of GPCR protein signaling pathway;   regulation of GPCR protein signalling pathway


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regulation of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1 adenylate cyclase activating polypeptide 1 involved_in ISO (PMID:11175907) UniProt PMID:11175907 NCBI chr 7:67,682,421...67,691,035 JBrowse link
G ARRB1 arrestin beta 1 acts_upstream_of_or_within ISO (MGI:1101531|PMID:9400383), (MGI:1930835|PMID:11171997) RGD
MGI
PMID:1517224 PMID:9400383 PMID:11171997 MGI:1101531 MGI:1930835 RGD:631708 NCBI chr21:23,261,020...23,304,448
Ensembl chr21:23,235,711...23,297,786
JBrowse link
G ARRB2 arrestin beta 2 acts_upstream_of_or_within ISO (MGI:1351102|PMID:10617462), (MGI:1927976|PMID:11130073), (MGI:1930835|PMID:11171997) RGD
MGI
PMID:1517224 PMID:10617462 PMID:11130073 PMID:11171997 MGI:1351102 MGI:1927976 MGI:1930835 RGD:631708 NCBI chr 5:31,831,208...31,838,875
Ensembl chr 5:31,829,864...31,839,454
JBrowse link
G DGKQ diacylglycerol kinase theta involved_in ISO (PMID:22732145) ParkinsonsUK-UCL PMID:22732145 NCBI chr 3:91,544,350...91,554,494
Ensembl chr 3:91,544,219...91,554,565
JBrowse link
G DYNLT1 dynein light chain Tctex-type 1 involved_in ISO (MGI:5788400|PMID:10559191) UniProt PMID:10559191 MGI:5788400 NCBI chr 1:48,058,804...48,066,389
Ensembl chr 1:48,058,804...48,066,609
JBrowse link
G FRMPD1 FERM and PDZ domain containing 1 involved_in ISO (PMID:18566450) UniProt PMID:18566450 NCBI chr11:53,901,625...54,051,885
Ensembl chr11:53,939,807...54,051,756
JBrowse link
G GIT1 GIT ArfGAP 1 ISO RGD PMID:9826657 RGD:68782 NCBI chr 9:43,676,707...43,686,566
Ensembl chr 9:43,677,899...43,693,177
JBrowse link
G GPSM1 G protein signaling modulator 1 ISO RGD PMID:10559191 RGD:631950 NCBI chr 9:49,124,828...49,152,079
Ensembl chr 9:49,118,627...49,152,208
JBrowse link
G GRK5 G protein-coupled receptor kinase 5 ISO RGD PMID:8626574 RGD:61618 NCBI chr28:29,424,350...29,636,552
Ensembl chr28:29,424,593...29,632,741
JBrowse link
G ITGB1 integrin subunit beta 1 ISO RGD PMID:17157995 RGD:1625132 NCBI chr 2:3,728,472...3,757,696
Ensembl chr 2:3,670,596...3,756,961
JBrowse link
G ITGB3 integrin subunit beta 3 ISO RGD PMID:17157995 RGD:1625132 NCBI chr 9:9,179,667...9,231,061
Ensembl chr 9:9,182,562...9,231,451
JBrowse link
G KCTD12 potassium channel tetramerization domain containing 12 acts_upstream_of_or_within ISO (MGI:4462115|PMID:20400944) MGI PMID:20400944 MGI:4462115 NCBI chr22:30,506,906...30,508,782
Ensembl chr22:30,503,932...30,508,632
JBrowse link
G KCTD16 potassium channel tetramerization domain containing 16 acts_upstream_of_or_within ISO (MGI:4462115|PMID:20400944) MGI PMID:20400944 MGI:4462115 NCBI chr 2:38,939,603...39,199,647
Ensembl chr 2:38,942,026...39,187,964
JBrowse link
G KCTD8 potassium channel tetramerization domain containing 8 acts_upstream_of_or_within ISO (MGI:4462115|PMID:20400944) MGI PMID:20400944 MGI:4462115 NCBI chr13:40,774,055...40,977,984
Ensembl chr13:40,738,332...40,977,969
JBrowse link
G PDC phosducin involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:19,498,785...19,514,225
Ensembl chr 7:19,498,788...19,514,228
JBrowse link
G PDCL phosducin like involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:59,945,988...59,955,295
Ensembl chr 9:59,947,559...59,954,040
JBrowse link
G PDE4D phosphodiesterase 4D ISO RGD PMID:12552097 RGD:629543 NCBI chr 2:45,843,767...47,245,263
Ensembl chr 2:45,846,294...46,949,912
JBrowse link
G PHF24 PHD finger protein 24 acts_upstream_of_or_within ISO (MGI:5616490|PMID:25242222) MGI PMID:25242222 MGI:5616490 NCBI chr11:51,552,345...51,580,762
Ensembl chr11:51,569,770...51,577,059
JBrowse link
G PLCB1 phospholipase C beta 1 involved_in ISO (MGI:4943665|PMID:18493969) BHF-UCL PMID:18493969 MGI:4943665 NCBI chr24:13,337,285...13,996,218
Ensembl chr24:13,322,296...13,995,539
JBrowse link
G PLCE1 phospholipase C epsilon 1 involved_in ISO (PMID:11022047) UniProt PMID:11022047 NCBI chr28:8,209,707...8,484,427
Ensembl chr28:8,210,058...8,481,770
JBrowse link
G RGS1 regulator of G protein signaling 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr38:6,372,451...6,376,427
Ensembl chr38:6,372,558...6,376,315
JBrowse link
G RGS10 regulator of G protein signaling 10 involved_in IEA InterPro GO_REF:0000002 NCBI chr28:29,673,357...29,711,887
Ensembl chr28:29,673,374...29,713,908
JBrowse link
G RGS14 regulator of G protein signaling 14 ISO RGD PMID:11976690 RGD:729762 NCBI chr 4:35,984,970...35,999,386
Ensembl chr 4:35,985,132...35,999,294
JBrowse link
G RGS18 regulator of G protein signaling 18 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1927493|PMID:11042171) Ensembl
MGI
PMID:11042171 GO_REF:0000107 MGI:1927493 NCBI chr38:6,729,056...6,743,522
Ensembl chr38:6,730,328...6,743,396
JBrowse link
G RGS2 regulator of G protein signaling 2 involved_in ISO (PMID:19478087) UniProt PMID:19478087 NCBI chr38:6,200,237...6,203,491
Ensembl chr38:6,200,657...6,203,494
JBrowse link
G RGS7 regulator of G protein signaling 7 acts_upstream_of_or_within ISO (MGI:5428056|PMID:22689652) RGD
MGI
PMID:10092682 PMID:22689652 MGI:5428056 RGD:69962 NCBI chr 7:32,296,337...32,792,085
Ensembl chr 7:32,296,695...32,792,036
JBrowse link
G RGS9 regulator of G protein signaling 9 ISO RGD PMID:9765512 RGD:69964 NCBI chr 9:14,809,977...14,905,299
Ensembl chr 9:14,809,864...14,905,197
JBrowse link
G RIC8B RIC8 guanine nucleotide exchange factor B acts_upstream_of_or_within ISO (PMID:12652642) MGI PMID:12652642 NCBI chr10:31,883,764...31,982,622
Ensembl chr10:31,885,041...31,982,514
JBrowse link
G SLC24A4 solute carrier family 24 member 4 acts_upstream_of ISO (MGI:6716959|PMID:25096581) ARUK-UCL PMID:25096581 MGI:6716959 NCBI chr 8:1,570,833...1,685,135
Ensembl chr 8:1,517,560...1,680,208
JBrowse link
G TUB TUB bipartite transcription factor acts_upstream_of_or_within ISO (MGI:5921791|PMID:28154160) MGI PMID:28154160 MGI:5921791 NCBI chr21:31,566,095...31,629,545
Ensembl chr21:31,566,130...31,625,101
JBrowse link
G TULP3 TUB like protein 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:28154160)
(MGI:5921791|PMID:28154160)
Ensembl
MGI
PMID:28154160 GO_REF:0000107 MGI:5921791 NCBI chr27:41,819,574...41,884,198
Ensembl chr27:41,819,455...41,884,097
JBrowse link
G USP20 ubiquitin specific peptidase 20 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:53,966,180...54,009,312
Ensembl chr 9:53,966,183...54,009,317
JBrowse link
G USP33 ubiquitin specific peptidase 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:69,118,953...69,170,864
Ensembl chr 6:69,118,333...69,169,966
JBrowse link
G ZDHHC3 zinc finger DHHC-type palmitoyltransferase 3 involved_in ISO (MGI:3831644|PMID:19001095)
(PMID:19001095)
UniProt PMID:19001095 MGI:3831644 NCBI chr20:43,379,669...43,433,101
Ensembl chr20:43,379,722...43,431,414
JBrowse link
G ZDHHC7 zinc finger DHHC-type palmitoyltransferase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:67,554,310...67,580,042
Ensembl chr 5:67,566,563...67,578,556
JBrowse link
cross-receptor inhibition within G protein-coupled receptor heterodimer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALCR calcitonin receptor involved_in ISO (PMID:14722252) UniProt PMID:14722252 NCBI chr14:18,923,116...19,074,904
Ensembl chr14:18,923,116...19,074,904
JBrowse link
G RAMP3 receptor activity modifying protein 3 involved_in ISO (PMID:14722252) UniProt PMID:14722252
desensitization of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GIPR gastric inhibitory polypeptide receptor ISO RGD PMID:8928774 RGD:2312614 NCBI chr 1:109,898,617...109,909,331
Ensembl chr 1:109,899,874...109,909,410
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:21873635)
(MGI:84440|PMID:7761854)
(MGI:1337704|PMID:10338466)
RGD
GO_Central
MGI
PMID:7761854 PMID:10338466 PMID:17908240 PMID:21873635 PMID:30075183 MGI:1337704 MGI:84440 RGD:13792694 RGD:7242040 NCBI chr18:50,148,566...50,167,422
Ensembl chr18:50,148,598...50,167,428
JBrowse link
G GRK3 G protein-coupled receptor kinase 3 ISO RGD PMID:8381966 PMID:20837135 RGD:5685022 RGD:5685621 NCBI chr26:19,385,059...19,512,528
Ensembl chr26:19,385,058...19,516,077
JBrowse link
G GRK4 G protein-coupled receptor kinase 4 ISO RGD PMID:15166006 RGD:1598508 NCBI chr 3:61,233,066...61,331,094
Ensembl chr 3:61,079,904...61,330,290
JBrowse link
G GRK5 G protein-coupled receptor kinase 5 ISO RGD PMID:8626574 PMID:30075183 RGD:13792694 RGD:61618 NCBI chr28:29,424,350...29,636,552
Ensembl chr28:29,424,593...29,632,741
JBrowse link
G GRK6 G protein-coupled receptor kinase 6 ISO RGD PMID:12810562 PMID:17908240 RGD:1299124 RGD:7242040 NCBI chr 4:35,927,470...35,943,218
Ensembl chr 4:35,913,472...35,943,221
JBrowse link
G GRM5 glutamate metabotropic receptor 5 involved_in ISO PMID:12514208 UniProt PMID:12514208 RGD:728711 NCBI chr21:10,980,186...11,496,539
Ensembl chr21:10,996,075...11,493,290
JBrowse link
G LOC102154767 lymphocyte antigen 6G6e-like involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:5694852|PMID:26276394)
GO_Central
MGI
PMID:21873635 PMID:26276394 MGI:5694852 NCBI chr12:1,189,910...1,196,762 JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:9350980 RGD:9850278 NCBI chr 6:74,932,789...74,986,573 JBrowse link
desensitization of G protein-coupled receptor signaling pathway by arrestin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 involved_in ISS HGNC-UCL GO_REF:0000024 NCBI chr 4:60,048,502...60,050,447
Ensembl chr 4:59,941,517...60,050,298
JBrowse link
G ADRB3 adrenoceptor beta 3 NOT|involved_in ISO (PMID:15123695) HGNC-UCL PMID:15123695 NCBI chr16:27,445,601...27,446,796
Ensembl chr16:27,445,601...27,447,521
JBrowse link
G ARRB2 arrestin beta 2 involved_in ISO (PMID:12582207) RGD
UniProt
PMID:12582207 PMID:20705669 RGD:5509896 NCBI chr 5:31,831,208...31,838,875
Ensembl chr 5:31,829,864...31,839,454
JBrowse link
G protein-coupled receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN2 beclin 2 acts_upstream_of_or_within
involved_in
ISO (MGI:5528919|PMID:23954414)
(PMID:23954414)
MGI
UniProt
PMID:23954414 MGI:5528919 NCBI chr 7:33,318,124...33,356,388
Ensembl chr 7:33,317,730...33,350,325
JBrowse link
G GPRASP1 G protein-coupled receptor associated sorting protein 1 involved_in
acts_upstream_of_or_within
ISO (PMID:23954414) UniProt
MGI
PMID:23954414 NCBI chr  X:76,274,196...76,318,204
Ensembl chr  X:76,313,740...76,318,607
Ensembl chr  X:76,313,740...76,318,607
JBrowse link
G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADM adrenomedullin involved_in ISO (PMID:10882736) UniProt PMID:10882736 NCBI chr21:33,472,197...33,474,472
Ensembl chr21:33,471,623...33,474,495
JBrowse link
G ARRB1 arrestin beta 1 involved_in ISO (PMID:10521508), (PMID:12582207) UniProt PMID:10521508 PMID:12582207 NCBI chr21:23,261,020...23,304,448
Ensembl chr21:23,235,711...23,297,786
JBrowse link
G ARRB2 arrestin beta 2 involved_in ISO (PMID:10644702)
(PMID:12582207)
UniProt PMID:10644702 PMID:12582207 NCBI chr 5:31,831,208...31,838,875
Ensembl chr 5:31,829,864...31,839,454
JBrowse link
G CRSP-3 calcitonin receptor-stimulating peptide 3 involved_in ISO (PMID:10882736) UniProt PMID:10882736 NCBI chr21:37,676,841...37,680,643
Ensembl chr21:37,676,841...37,680,645
JBrowse link
G DNM1 dynamin 1 ISO RGD PMID:14709338 RGD:9685157 NCBI chr 9:55,252,802...55,298,244
Ensembl chr 9:55,252,347...55,298,244
JBrowse link
G DNM2 dynamin 2 ISO RGD PMID:14709338 RGD:9685157 NCBI chr20:50,398,866...50,487,303
Ensembl chr20:50,398,864...50,487,241
JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:14617818 RGD:1581465 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241
JBrowse link
G DRD3 dopamine receptor D3 involved_in ISO (PMID:18424554) RGD
BHF-UCL
PMID:14617818 PMID:18424554 RGD:1581465 NCBI chr33:18,369,362...18,414,465
Ensembl chr33:18,372,865...18,412,277
JBrowse link
G GRK4 G protein-coupled receptor kinase 4 ISO RGD PMID:12519791 RGD:1304268 NCBI chr 3:61,233,066...61,331,094
Ensembl chr 3:61,079,904...61,330,290
JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:38,659,088...38,659,546 JBrowse link
G HTR2B 5-hydroxytryptamine receptor 2B involved_in ISO (MGI:4821070|PMID:17325130) UniProt PMID:17325130 MGI:4821070 NCBI chr25:43,042,306...43,056,361
Ensembl chr25:43,042,173...43,056,612
JBrowse link
G PLD2 phospholipase D2 acts_upstream_of_or_within ISO (MGI:3042801|PMID:14718562) MGI PMID:14718562 MGI:3042801 NCBI chr 5:31,755,881...31,767,131
Ensembl chr 5:31,756,433...31,767,066
JBrowse link
negative regulation of adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase involved_in ISO (PMID:16670267) UniProt PMID:16670267 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160
JBrowse link
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRDC3 arrestin domain containing 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5302794|PMID:21982743) Ensembl
MGI
PMID:21982743 GO_REF:0000107 MGI:5302794 NCBI chr 3:17,691,631...17,705,507
Ensembl chr 3:17,691,961...17,703,308
JBrowse link
G CRTC3 CREB regulated transcription coactivator 3 acts_upstream_of_or_within ISO (MGI:4867567|PMID:21164481) MGI PMID:21164481 MGI:4867567 NCBI chr 3:53,564,244...53,669,778
Ensembl chr 3:53,563,597...53,649,809
JBrowse link
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:321,246...420,262
Ensembl chr38:366,656...416,952
JBrowse link
G GNAI2 G protein subunit alpha i2 ISO RGD PMID:12631586 RGD:13508593 NCBI chr20:39,075,085...39,094,697
Ensembl chr20:39,075,085...39,094,697
JBrowse link
G PDE4B phosphodiesterase 4B involved_in ISO (MGI:5286798|PMID:21670503) BHF-UCL PMID:21670503 MGI:5286798 NCBI chr 5:44,063,145...44,606,070
Ensembl chr 5:44,065,106...44,500,999
JBrowse link
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APLP1 amyloid beta precursor like protein 1 involved_in ISO (PMID:16531006) BHF-UCL PMID:16531006 NCBI chr 1:116,774,392...116,783,101
Ensembl chr 1:116,728,529...116,783,046
JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 acts_upstream_of_or_within ISO (MGI:3850921|PMID:19246489) MGI PMID:19246489 MGI:3850921 NCBI chr14:43,366,849...43,414,398
Ensembl chr14:43,368,340...43,415,142
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:30075183 RGD:13792694 NCBI chr18:50,148,566...50,167,422
Ensembl chr18:50,148,598...50,167,428
JBrowse link
G GRK5 G protein-coupled receptor kinase 5 ISO RGD PMID:30075183 RGD:13792694 NCBI chr28:29,424,350...29,636,552
Ensembl chr28:29,424,593...29,632,741
JBrowse link
G MRAP melanocortin 2 receptor accessory protein involved_in ISO (PMID:19329486) BHF-UCL PMID:19329486 NCBI chr31:27,058,469...27,085,704
Ensembl chr31:27,058,366...27,087,573
JBrowse link
G MRAP2 melanocortin 2 receptor accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:44,323,932...44,373,170
Ensembl chr12:44,324,197...44,373,138
JBrowse link
G OPRL1 opioid related nociceptin receptor 1 ISO RGD PMID:15748148 RGD:9835006 NCBI chr24:47,530,039...47,537,477
Ensembl chr24:47,508,136...47,537,250
JBrowse link
G OPRM1 opioid receptor mu 1 ISO RGD PMID:15748148 RGD:9835006 NCBI chr 1:43,972,915...44,037,477
Ensembl chr 1:43,972,219...44,141,238
JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:9013884 RGD:9850263 NCBI chr 6:74,932,789...74,986,573 JBrowse link
negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RGS2 regulator of G protein signaling 2 involved_in ISO (MGI:5009116|PMID:21291891) BHF-UCL PMID:21291891 MGI:5009116 NCBI chr38:6,200,237...6,203,491
Ensembl chr38:6,200,657...6,203,494
JBrowse link
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UBQLN2 ubiquilin 2 involved_in ISO (PMID:18199683) UniProt PMID:18199683 NCBI chr  X:47,860,923...47,864,282 JBrowse link
negative regulation of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL5 C-C motif chemokine ligand 5 involved_in ISO (PMID:10734056) UniProt PMID:10734056 NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852
JBrowse link
G CRY1 cryptochrome circadian regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:31,681,098...31,792,995
Ensembl chr10:31,681,288...31,780,306
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:62,435,035...62,438,354
Ensembl chr13:62,434,422...62,438,354
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:1403099 RGD:632163 NCBI chr18:50,148,566...50,167,422
Ensembl chr18:50,148,598...50,167,428
JBrowse link
G KLK14 kallikrein related peptidase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:105,811,435...105,816,625
Ensembl chr 1:105,812,224...105,816,625
JBrowse link
G MGRN1 mahogunin ring finger 1 involved_in ISO (PMID:19737927) UniProt PMID:19737927 NCBI chr 6:36,716,071...36,775,893
Ensembl chr 6:36,716,343...36,769,417
JBrowse link
G PLEK pleckstrin involved_in ISO (PMID:7782310) BHF-UCL PMID:7782310 NCBI chr10:67,395,972...67,421,247
Ensembl chr10:67,395,972...67,421,247
JBrowse link
G RGS12 regulator of G protein signaling 12 ISO RGD PMID:9651375 RGD:69959 NCBI chr 3:60,917,033...61,011,812
Ensembl chr 3:60,917,072...61,009,131
JBrowse link
G RGS13 regulator of G protein signaling 13 acts_upstream_of_or_within ISO (MGI:2385407|PMID:12193720) MGI PMID:12193720 MGI:2385407 NCBI chr38:6,291,146...6,316,662
Ensembl chr38:6,291,182...6,315,198
JBrowse link
G RGS14 regulator of G protein signaling 14 involved_in ISO (MGI:5009199|PMID:10926822) UniProt PMID:10926822 MGI:5009199 NCBI chr 4:35,984,970...35,999,386
Ensembl chr 4:35,985,132...35,999,294
JBrowse link
G RGS2 regulator of G protein signaling 2 involved_in ISO (MGI:3836877|PMID:19127022) RGD
BHF-UCL
PMID:11968023 PMID:19127022 PMID:21798518 MGI:3836877 RGD:633858 RGD:7207364 NCBI chr38:6,200,237...6,203,491
Ensembl chr38:6,200,657...6,203,494
JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:9918533 PMID:21798518 RGD:7207364 RGD:7207376 NCBI chr38:19,771,454...19,778,917
Ensembl chr38:19,771,441...19,779,190
JBrowse link
G RPGRIP1L RPGRIP1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:62,080,159...62,179,694
Ensembl chr 2:62,080,080...62,178,284
JBrowse link
G RPH3AL rabphilin 3A like (without C2 domains) acts_upstream_of_or_within ISO (MGI:3044444|PMID:15159548) MGI PMID:15159548 MGI:3044444 NCBI chr 9:45,315,713...45,421,937
Ensembl chr 9:45,320,027...45,420,981
JBrowse link
G YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:32,304,808...32,325,789
Ensembl chr24:32,304,812...32,323,938
JBrowse link
negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BICD1 BICD cargo adaptor 1 involved_in ISO PMID:20164183
(MGI:4887309|PMID:20164183)
BHF-UCL PMID:20164183 MGI:4887309 RGD:8693367 NCBI chr27:16,478,323...16,618,429
Ensembl chr27:16,484,121...16,612,044
JBrowse link
negative regulation of thrombin-activated receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MET MET proto-oncogene, receptor tyrosine kinase involved_in ISO (PMID:25198505) CAFA PMID:25198505 NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027
JBrowse link
G SNCA synuclein alpha involved_in ISO (PMID:12239163) UniProt PMID:12239163 NCBI chr32:12,915,871...13,079,338
Ensembl chr32:12,916,215...13,060,383
JBrowse link
G STMN1 stathmin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:74,035,462...74,043,352
Ensembl chr 2:74,035,457...74,043,349
JBrowse link
positive regulation of adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP3 acid phosphatase 3 involved_in ISS UniProt GO_REF:0000024 NCBI chr23:29,294,641...29,353,970
Ensembl chr23:29,294,843...29,343,499
JBrowse link
G CNTN2 contactin 2 acts_upstream_of_or_within ISO (MGI:1930847|PMID:11178983) MGI PMID:11178983 MGI:1930847 NCBI chr38:1,570,598...1,600,524
Ensembl chr38:1,576,898...1,596,621
JBrowse link
positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSK3A glycogen synthase kinase 3 alpha involved_in ISO (MGI:4829580|PMID:20516643) BHF-UCL PMID:20516643 MGI:4829580 NCBI chr 1:112,129,116...112,138,714
Ensembl chr 1:112,103,825...112,138,559
JBrowse link
positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOS1 nitric oxide synthase 1 involved_in ISO (MGI:3771112|PMID:17242280) BHF-UCL PMID:17242280 MGI:3771112 NCBI chr26:13,787,341...13,895,176
Ensembl chr26:13,786,309...13,962,332
JBrowse link
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:18202135 RGD:5129138 NCBI chr28:24,908,224...24,909,684
Ensembl chr28:24,908,224...24,909,684
JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 acts_upstream_of_or_within ISO (MGI:3850921|PMID:19246489) MGI PMID:19246489 MGI:3850921 NCBI chr14:43,366,849...43,414,398
Ensembl chr14:43,368,340...43,415,142
JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in ISO (MGI:4829580|PMID:20516643) BHF-UCL PMID:20516643 MGI:4829580 NCBI chr 1:112,129,116...112,138,714
Ensembl chr 1:112,103,825...112,138,559
JBrowse link
G MRAP melanocortin 2 receptor accessory protein involved_in ISO (PMID:19329486) BHF-UCL PMID:19329486 NCBI chr31:27,058,469...27,085,704
Ensembl chr31:27,058,366...27,087,573
JBrowse link
G MRAP2 melanocortin 2 receptor accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:44,323,932...44,373,170
Ensembl chr12:44,324,197...44,373,138
JBrowse link
positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRMT5 protein arginine methyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:3,248,349...3,257,567
Ensembl chr 8:3,248,404...3,257,456
JBrowse link
positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGB3 integrin subunit beta 3 ISO RGD PMID:17157995 RGD:1625132 NCBI chr 9:9,179,667...9,231,061
Ensembl chr 9:9,182,562...9,231,451
JBrowse link
positive regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APELA apelin receptor early endogenous ligand involved_in ISO (PMID:25639753) UniProt PMID:25639753 NCBI chr15:60,967,944...60,990,955 JBrowse link
G APLN apelin involved_in ISO (PMID:11359874)
(MGI:5902690|PMID:11359874)
UniProt PMID:11359874 MGI:5902690 RGD:12907555 NCBI chr  X:100,863,360...100,873,105 JBrowse link
G APP amyloid beta precursor protein involved_in ISO (PMID:18723082) ARUK-UCL PMID:18723082 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337
JBrowse link
positive regulation of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein involved_in ISO (PMID:11316806) ARUK-UCL PMID:11316806 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337
JBrowse link
G C3 complement C3 involved_in ISO (PMID:15833747) UniProt PMID:15833747 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761
JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:18809670 RGD:2311559 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241
JBrowse link
G ECE1 endothelin converting enzyme 1 ISO RGD PMID:15733912 RGD:1581735 NCBI chr 2:77,732,645...77,793,950
Ensembl chr 2:77,678,686...77,792,114
JBrowse link
G FGF8 fibroblast growth factor 8 acts_upstream_of_or_within ISO (MGI:3847828|PMID:19307307) MGI PMID:19307307 MGI:3847828 NCBI chr28:14,362,407...14,367,109
Ensembl chr28:14,362,109...14,367,468
JBrowse link
G GAS2L2 growth arrest specific 2 like 2 involved_in ISO (MGI:6355742|PMID:23994616) UniProt PMID:23994616 MGI:6355742 RGD:14697711 NCBI chr 9:37,917,863...37,926,149
Ensembl chr 9:37,918,269...37,927,083
JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:15,792,072...15,796,922
Ensembl chr 6:15,792,897...15,794,051
JBrowse link
G KLK14 kallikrein related peptidase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:105,811,435...105,816,625
Ensembl chr 1:105,812,224...105,816,625
JBrowse link
G KLK5 kallikrein related peptidase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:105,914,040...105,922,639
Ensembl chr 1:105,914,460...105,922,296
JBrowse link
G KLK6 kallikrein related peptidase 6 involved_in ISO (PMID:16885167) UniProt PMID:16885167 NCBI chr 1:105,902,147...105,907,585 JBrowse link
G MYH9 myosin heavy chain 9 ISO RGD PMID:20068007 RGD:6902910 NCBI chr10:28,063,626...28,122,953
Ensembl chr10:28,063,624...28,122,953
JBrowse link
G PDE6G phosphodiesterase 6G involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:2156093|PMID:11502744)
GO_Central
MGI
PMID:11502744 PMID:21873635 MGI:2156093 NCBI chr 9:525,123...529,406
Ensembl chr 9:526,577...529,526
JBrowse link
G PDE6H phosphodiesterase 6H involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:2156093|PMID:11502744)
GO_Central
MGI
PMID:11502744 PMID:21873635 MGI:2156093 NCBI chr27:31,640,731...31,664,494
Ensembl chr27:31,640,737...31,664,401
JBrowse link
G PHB prohibitin involved_in ISO (PMID:24732013) UniProt PMID:24732013 NCBI chr 9:25,525,711...25,536,722
Ensembl chr 9:25,526,649...25,536,722
JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2670839|PMID:12878180) Ensembl
MGI
PMID:12878180 GO_REF:0000107 MGI:2670839 NCBI chr18:55,426,632...55,431,916
Ensembl chr18:55,429,308...55,430,510
JBrowse link
G SLC39A14 solute carrier family 39 member 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:34,854,371...34,901,030
Ensembl chr25:34,846,653...34,869,695
JBrowse link
G TMOD2 tropomodulin 2 acts_upstream_of_or_within ISO (MGI:2663390|PMID:12799133) MGI PMID:12799133 MGI:2663390 NCBI chr30:17,425,216...17,501,484
Ensembl chr30:17,455,987...17,592,580
JBrowse link
positive regulation of inhibitory G protein-coupled receptor phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APLNR apelin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:38,878,621...38,882,280
Ensembl chr18:38,878,947...38,886,206
JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:15937517 RGD:10043344 NCBI chr 6:74,932,789...74,986,573 JBrowse link
positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHGA chromogranin A ISO RGD PMID:11257446 RGD:6907050 NCBI chr 8:1,970,966...1,973,511 JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459
JBrowse link
G GPR27 G protein-coupled receptor 27 acts_upstream_of_or_within ISO (MGI:5311513|PMID:22253604) MGI PMID:22253604 MGI:5311513
G GRP gastrin releasing peptide involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:16,974,818...16,987,578
Ensembl chr 1:16,975,113...16,987,531
JBrowse link
prostaglandin receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:15937517 RGD:10043344 NCBI chr 6:74,932,789...74,986,573 JBrowse link
protein kinase C deactivation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDN1 endothelin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383
JBrowse link
regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MRAP2 melanocortin 2 receptor accessory protein 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:44,323,932...44,373,170
Ensembl chr12:44,324,197...44,373,138
JBrowse link
G PDE10A phosphodiesterase 10A acts_upstream_of_or_within ISO (MGI:3815363|PMID:18923023) MGI PMID:18923023 MGI:3815363 NCBI chr 1:53,457,781...54,049,735
Ensembl chr 1:53,462,979...53,801,966
JBrowse link
G PDE4A phosphodiesterase 4A acts_upstream_of_or_within ISO (MGI:3815363|PMID:18923023) MGI PMID:18923023 MGI:3815363 NCBI chr20:50,672,012...50,723,318
Ensembl chr20:50,672,363...50,811,160
JBrowse link
regulation of angiotensin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ROCK1 Rho associated coiled-coil containing protein kinase 1 involved_in ISO (PMID:28679962) ARUK-UCL PMID:28679962 NCBI chr 7:66,862,614...67,001,538
Ensembl chr 7:66,862,608...67,142,853
JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 involved_in ISO (MGI:6158813|PMID:28679962) ARUK-UCL PMID:28679962 MGI:6158813 NCBI chr17:7,931,786...8,012,484
Ensembl chr17:7,934,739...8,178,707
JBrowse link
regulation of endocannabinoid signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD6 abhydrolase domain containing 6, acylglycerol lipase acts_upstream_of_or_within ISO (MGI:4829719|PMID:20657592) MGI PMID:20657592 MGI:4829719 NCBI chr20:32,301,120...32,331,030
Ensembl chr20:32,302,104...32,330,998
JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha involved_in ISO (MGI:5494205|PMID:23502535) UniProt PMID:23502535 MGI:5494205 NCBI chr 4:58,800,818...58,865,830
Ensembl chr 4:58,800,813...58,865,830
JBrowse link
G MGLL monoglyceride lipase involved_in ISO (MGI:4836780|PMID:20729846) UniProt PMID:20729846 MGI:4836780 NCBI chr20:1,765,650...1,880,710
Ensembl chr20:1,766,216...1,943,588
JBrowse link
regulation of opioid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPP1R9B protein phosphatase 1 regulatory subunit 9B involved_in ISO (MGI:3834288|PMID:18439408) UniProt PMID:18439408 MGI:3834288 NCBI chr 9:26,135,982...26,152,303
Ensembl chr 9:26,137,464...26,151,810
JBrowse link
G SYP synaptophysin involved_in ISO PMID:17005904 UniProt PMID:17005904 RGD:8554727 NCBI chr  X:42,288,071...42,301,802
Ensembl chr  X:42,288,148...42,299,487
JBrowse link
regulation of rhodopsin mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIPL1 aryl hydrocarbon receptor interacting protein like 1 acts_upstream_of_or_within ISO (MGI:3054134|PMID:15365178)
(MGI:3054118|PMID:15365173)
MGI PMID:15365173 PMID:15365178 MGI:3054118 MGI:3054134 NCBI chr 5:30,824,571...30,835,025
Ensembl chr 5:30,824,683...30,834,128
JBrowse link
G GRK1 G protein-coupled receptor kinase 1 involved_in ISO (PMID:15946941) UniProt PMID:15946941 NCBI chr22:60,911,953...60,929,330
Ensembl chr22:60,911,953...60,926,146
JBrowse link
termination of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RGS12 regulator of G protein signaling 12 ISO RGD PMID:11130074 RGD:7207399 NCBI chr 3:60,917,033...61,011,812
Ensembl chr 3:60,917,072...61,009,131
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13863
    signaling 4959
      regulation of signaling 3226
        regulation of signal transduction 2712
          regulation of G protein-coupled receptor signaling pathway 127
            cross-receptor inhibition within G protein-coupled receptor heterodimer 2
            modulation by symbiont of host G protein-coupled receptor signal transduction + 0
            negative regulation of G protein-coupled receptor signaling pathway + 59
            positive regulation of G protein-coupled receptor signaling pathway + 31
            protein kinase C deactivation 1
            regulation of G protein-coupled receptor internalization + 4
            regulation of adenosine receptor signaling pathway + 3
            regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 19
            regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway + 1
            regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway + 1
            regulation of angiotensin-activated signaling pathway + 2
            regulation of endocannabinoid signaling pathway 3
            regulation of octopamine or tyramine signaling pathway + 0
            regulation of opioid receptor signaling pathway + 3
            regulation of phospholipase C-activating G protein-coupled receptor signaling pathway + 5
            regulation of rhodopsin mediated signaling pathway + 2
            regulation of thrombin-activated receptor signaling pathway + 3
Path 2
Term Annotations click to browse term
  biological_process 13863
    biological regulation 10006
      regulation of biological process 9446
        regulation of cellular process 8979
          signal transduction 4410
            G protein-coupled receptor signaling pathway 630
              regulation of G protein-coupled receptor signaling pathway 127
                cross-receptor inhibition within G protein-coupled receptor heterodimer 2
                modulation by symbiont of host G protein-coupled receptor signal transduction + 0
                negative regulation of G protein-coupled receptor signaling pathway + 59
                positive regulation of G protein-coupled receptor signaling pathway + 31
                protein kinase C deactivation 1
                regulation of G protein-coupled receptor internalization + 4
                regulation of adenosine receptor signaling pathway + 3
                regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 19
                regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway + 1
                regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway + 1
                regulation of angiotensin-activated signaling pathway + 2
                regulation of endocannabinoid signaling pathway 3
                regulation of octopamine or tyramine signaling pathway + 0
                regulation of opioid receptor signaling pathway + 3
                regulation of phospholipase C-activating G protein-coupled receptor signaling pathway + 5
                regulation of rhodopsin mediated signaling pathway + 2
                regulation of thrombin-activated receptor signaling pathway + 3
paths to the root