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ONTOLOGY REPORT - ANNOTATIONS

Term:calcium, potassium:sodium antiporter activity
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Accession:GO:0008273 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + K+(in) + Na+(out) = Ca2+(out) + K+(out) + Na+(in).
Synonyms:related_synonym: potassium-dependent sodium/calcium exchanger
 xref: RHEA:69967;   Reactome:R-HSA-5625841 "Defective SLC24A1 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+";   Reactome:R-HSA-5626270 "Defective SLC24A4 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+";   Reactome:R-HSA-5626356 "Defective SLC24A5 does not exchange cytosolic 4Na+ for Golgi luminal Ca2+, K+";   reactome:R-HSA-2514891 "SLC24A1 exchanges 4Na+ for Ca2+, K+";   reactome:R-HSA-425678 "SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+";   reactome:R-HSA-5626316 "SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+"


show annotations for term's descendants           Sort by:
calcium, potassium:sodium antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc24a1 solute carrier family 24 member 1 enables ISO
IEA
IBA		 (PMID:26631410)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:26631410 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:65,440,842...65,466,001
Ensembl chr 8:65,440,730...65,466,001 		JBrowse link
G Slc24a2 solute carrier family 24 member 2 enables IMP
IDA
ISO
IEA
IBA		 (PMID:10662833), (PMID:18166528), (PMID:26631410), (PMID:27093457)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:10662833 PMID:18166528 PMID:26631410 PMID:27093457 PMID:12377762 More... GO_REF:0000033 GO_REF:0000107, RGD:730066, RGD:7175087 NCBI chr 5:101,497,916...101,741,840
Ensembl chr 5:101,502,278...101,739,337 		JBrowse link
G Slc24a3 solute carrier family 24 member 3 enables IDA
ISO
IEA
IBA		 (PMID:26631410)
GO_REF:0000107
GO_REF:0000118
GO_REF:0000033
(PMID:11294880)		 RGD
Ensembl
TreeGrafter
GO_Central		 PMID:11294880 PMID:26631410 PMID:11294880 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118, RGD:68852 NCBI chr 3:132,552,119...133,051,192
Ensembl chr 3:132,551,595...133,051,192 		JBrowse link
G Slc24a4 solute carrier family 24 member 4 enables ISO
IBA		 (PMID:26631410)
(MGI:6718234|PMID:27093457)
GO_REF:0000033		 RGD
GO_Central		 PMID:26631410 PMID:27093457 GO_REF:0000033 MGI:6718234 NCBI chr 6:121,279,590...121,419,811
Ensembl chr 6:121,280,031...121,414,949 		JBrowse link
G Slc24a5 solute carrier family 24 member 5 enables ISO
IBA		 (PMID:18166528), (PMID:27093457)
GO_REF:0000033		 RGD
GO_Central		 PMID:18166528 PMID:27093457 GO_REF:0000033 NCBI chr 3:112,319,349...112,338,889
Ensembl chr 3:112,319,308...112,339,231 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    transporter activity 1259
      transmembrane transporter activity 1163
        monoatomic ion transmembrane transporter activity 752
          active monoatomic ion transmembrane transporter activity 257
            metal cation:monoatomic cation antiporter activity 41
              solute:potassium antiporter activity 19
                calcium, potassium:sodium antiporter activity 5
Path 2
Term Annotations click to browse term
  molecular_function 21010
    transporter activity 1259
      transmembrane transporter activity 1163
        inorganic molecular entity transmembrane transporter activity 695
          inorganic cation transmembrane transporter activity 582
            metal ion transmembrane transporter activity 461
              calcium ion transmembrane transporter activity 152
                calcium:monoatomic cation antiporter activity 12
                  calcium:sodium antiporter activity 9
                    calcium, potassium:sodium antiporter activity 5
paths to the root