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ONTOLOGY REPORT - ANNOTATIONS


Term:cell death
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Accession:GO:0008219 term browser browse the term
Definition:Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
Comment:This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term.
Synonyms:related_synonym: accidental cell death;   necrosis


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cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALS2 alsin Rho guanine nucleotide exchange factor ALS2 ISO RGD PMID:16802292 RGD:1599082 NCBI chr2B:88,954,167...89,034,764
Ensembl chr2B:207,108,952...207,189,623
JBrowse link
G ATP6AP1 ATPase H+ transporting accessory protein 1 ISO RGD PMID:10686355 RGD:2301245 NCBI chr  X:143,870,421...143,878,288
Ensembl chr  X:153,740,751...153,748,621
JBrowse link
G AXIN2 axin 2 ISO RGD PMID:15572025 RGD:1599426 NCBI chr17:59,476,336...59,509,358
Ensembl chr17:64,688,416...64,720,086
JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in ISO (PMID:10400625) UniProt PMID:10400625 NCBI chr 1:117,823,388...117,834,314 JBrowse link
G BNIP3 BCL2 interacting protein 3 ISO PMID:14972662 UniProt PMID:14972662 RGD:2314028 NCBI chr10:128,671,663...128,685,952
Ensembl chr10:132,858,211...132,871,634
JBrowse link
G BRINP1 BMP/retinoic acid inducible neural specific 1 involved_in ISO (PMID:14712213) UniProt PMID:14712213 NCBI chr 9:90,296,199...90,499,503
Ensembl chr 9:118,646,433...118,792,727
JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A involved_in ISO (PMID:16595610) UniProt PMID:16595610 NCBI chr19:12,769,586...13,189,022
Ensembl chr19:13,507,102...13,804,729
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO RGD PMID:17006629 RGD:2293617 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541
JBrowse link
G CIDEA cell death inducing DFFA like effector a ISO (MGI:3768618|PMID:17080483) BHF-UCL PMID:17080483 MGI:3768618 NCBI chr18:2,051,880...2,075,909 JBrowse link
G EMP1 epithelial membrane protein 1 involved_in ISO (PMID:12107182) UniProt PMID:12107182 NCBI chr12:13,207,586...13,227,669
Ensembl chr12:13,610,060...13,630,819
JBrowse link
G EMP2 epithelial membrane protein 2 involved_in ISO (PMID:12107182) UniProt PMID:12107182 NCBI chr16:9,465,589...9,517,593
Ensembl chr16:10,694,425...10,744,744
JBrowse link
G EMP3 epithelial membrane protein 3 involved_in ISO (PMID:12107182) UniProt PMID:12107182 NCBI chr19:45,326,302...45,331,462
Ensembl chr19:53,919,986...53,925,147
JBrowse link
G FAF1 Fas associated factor 1 involved_in ISO (PMID:15743842) UniProt PMID:15743842 NCBI chr 1:49,679,198...50,207,129
Ensembl chr 1:51,188,540...51,606,904
JBrowse link
G FBH1 F-box DNA helicase 1 involved_in ISO (PMID:23361013)
(PMID:23319600)
UniProt PMID:23319600 PMID:23361013 NCBI chr10:5,931,389...5,978,844
Ensembl chr10:5,915,713...5,962,778
JBrowse link
G GSDME gasdermin E involved_in ISO (PMID:26236191) UniProt PMID:26236191 NCBI chr 7:25,373,485...25,433,001
Ensembl chr 7:24,977,838...25,039,525
JBrowse link
G GZMM granzyme M involved_in ISO (PMID:21857942) UniProt PMID:21857942 NCBI chr19:584,712...591,186 JBrowse link
G HMOX1 heme oxygenase 1 ISO PMID:17430897 BHF-UCL PMID:17430897 RGD:8553479 NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO RGD PMID:16504407 RGD:1624391 NCBI chr13:27,976,415...28,042,941
Ensembl chr13:46,694,273...46,759,826
JBrowse link
G KLK8 kallikrein related peptidase 8 ISO (MGI:3766680|PMID:17629414) UniProt PMID:17629414 MGI:3766680 NCBI chr19:47,963,060...47,969,065
Ensembl chr19:56,852,838...56,858,549
JBrowse link
G MAP3K10 mitogen-activated protein kinase kinase kinase 10 ISO RGD PMID:11416147 RGD:2302272 NCBI chr19:37,236,438...37,260,314
Ensembl chr19:45,753,354...45,775,137
JBrowse link
G MAP3K11 mitogen-activated protein kinase kinase kinase 11 ISO RGD PMID:11416147 RGD:2302272 NCBI chr11:60,956,880...60,973,972
Ensembl chr11:64,291,635...64,307,737
JBrowse link
G MAP3K9 mitogen-activated protein kinase kinase kinase 9 ISO RGD PMID:11416147 RGD:2302272 NCBI chr14:51,310,565...51,396,994
Ensembl chr14:70,188,444...70,266,460
JBrowse link
G NDOR1 NADPH dependent diflavin oxidoreductase 1 involved_in ISO (PMID:16140270) UniProt PMID:16140270 NCBI chr 9:108,265,305...108,278,923
Ensembl chr 9:137,233,940...137,247,716
JBrowse link
G NUP62 nucleoporin 62 involved_in ISO (PMID:11244088) UniProt PMID:11244088 NCBI chr19:46,919,731...46,942,318 JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 ISO RGD PMID:12435393 RGD:633387 NCBI chr12:10,196,712...10,210,432
Ensembl chr12:10,445,202...10,461,071
JBrowse link
G P2RX7 purinergic receptor P2X 7 ISO (MGI:3664807|PMID:16116196), (MGI:3772554|PMID:18097031)
(MGI:3040567|PMID:14761980)
MGI PMID:14761980 PMID:16116196 PMID:18097031 MGI:3040567 MGI:3664807 MGI:3772554 NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068
JBrowse link
G PARP4 poly(ADP-ribose) polymerase family member 4 involved_in ISO (PMID:12140175) UniProt PMID:12140175 NCBI chr13:5,734,322...5,827,323
Ensembl chr13:24,029,405...24,113,075
JBrowse link
G PJVK pejvakin ISO (MGI:5907777|PMID:28089576)
(MGI:5887150|PMID:28209736)
MGI PMID:28089576 PMID:28209736 MGI:5887150 MGI:5907777 NCBI chr2B:65,708,635...65,725,766
Ensembl chr2B:183,413,265...183,423,224
JBrowse link
G PMP22 peripheral myelin protein 22 involved_in ISO (PMID:12107182) UniProt PMID:12107182 NCBI chr17:36,389,549...36,425,161
Ensembl chr17:41,038,302...41,073,872
JBrowse link
G PNPLA8 patatin like phospholipase domain containing 8 involved_in ISO (PMID:15695510) UniProt PMID:15695510 NCBI chr 7:100,456,096...100,511,836
Ensembl chr 7:113,177,202...113,230,799
JBrowse link
G PRKD2 protein kinase D2 involved_in ISO (PMID:17077180) BHF-UCL PMID:17077180 NCBI chr19:43,666,591...43,710,858
Ensembl chr19:52,195,303...52,237,731
JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in ISO (MGI:6305600|PMID:30988283)
(PMID:30988283)
UniProt PMID:30988283 MGI:6305600 NCBI chr 6:2,893,802...2,943,162
Ensembl chr 6:2,997,343...3,045,078
JBrowse link
G RRAGA Ras related GTP binding A involved_in ISO (PMID:8995684), (PMID:9394008) UniProt PMID:8995684 PMID:9394008 NCBI chr 9:18,868,781...18,870,356
Ensembl chr 9:19,362,599...19,363,540
JBrowse link
G SNCAIP synuclein alpha interacting protein involved_in ISO (PMID:16595633) CACAO PMID:16595633 NCBI chr 5:117,692,836...117,847,221
Ensembl chr 5:123,555,073...123,630,921
JBrowse link
G SUSD6 sushi domain containing 6 involved_in ISO (PMID:24652652) UniProt PMID:24652652 NCBI chr14:50,205,634...50,309,054
Ensembl chr14:69,123,618...69,180,370
JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISO (PMID:16227582) UniProt PMID:16227582 NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041
JBrowse link
G VAPA VAMP associated protein A involved_in ISO PMID:19289470
(PMID:19289470)
UniProt PMID:19289470 RGD:8554038 NCBI chr18:4,329,479...4,373,047
Ensembl chr18:6,612,105...6,637,829
JBrowse link
activation-induced cell death of T cells term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 involved_in ISO (PMID:14749367) MGI PMID:14749367 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756
JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 ISO (MGI:3580938|PMID:15879105) MGI PMID:15879105 MGI:3580938 NCBI chr16:3,351,825...3,381,914
Ensembl chr16:4,519,965...4,550,786
JBrowse link
G FAS Fas cell surface death receptor ISO (MGI:2670301|PMID:12702495)
(MGI:79355|PMID:8640868)
(MGI:73864|PMID:7602121)
MGI PMID:7602121 PMID:8640868 PMID:12702495 MGI:2670301 MGI:73864 MGI:79355 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO (MGI:1889048|PMID:7584142) MGI PMID:7584142 MGI:1889048 NCBI chr10:6,053,549...6,103,863 JBrowse link
G RPS6 ribosomal protein S6 ISO (MGI:3610868|PMID:16357222) MGI PMID:16357222 MGI:3610868 NCBI chr 9:19,185,455...19,189,504
Ensembl chr 9:19,674,380...19,677,722
JBrowse link
G SIVA1 SIVA1 apoptosis inducing factor involved_in ISO (PMID:16491128) HGNC-UCL PMID:16491128 NCBI chr14:85,404,148...85,408,254
Ensembl chr14:105,196,118...105,202,678
JBrowse link
anoikis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMF Bcl2 modifying factor involved_in ISO (PMID:11546872) MGI PMID:11546872 NCBI chr15:19,026,053...19,047,008
Ensembl chr15:37,281,655...37,302,075
JBrowse link
G DAPK2 death associated protein kinase 2 involved_in ISO (PMID:18957423) UniProt PMID:18957423 NCBI chr15:42,860,484...42,999,489 JBrowse link
G E2F1 E2F transcription factor 1 ISO (MGI:3028362|PMID:14667810) MGI PMID:14667810 MGI:3028362 NCBI chr20:29,963,083...29,973,860
Ensembl chr20:31,103,764...31,110,604
JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ISO (MGI:5819337|PMID:23778976) ParkinsonsUK-UCL PMID:23778976 MGI:5819337 NCBI chr  X:143,988,720...144,010,078
Ensembl chr  X:153,854,493...153,876,092
JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 ISO (MGI:5819337|PMID:23778976) ParkinsonsUK-UCL PMID:23778976 MGI:5819337 NCBI chr 6:88,398,329...88,470,926
Ensembl chr 6:91,664,263...91,737,468
JBrowse link
G SIK1 salt inducible kinase 1 ISO (MGI:4887544|PMID:19622832) BHF-UCL PMID:19622832 MGI:4887544 NCBI chr21:29,675,040...29,689,408 JBrowse link
G STK11 serine/threonine kinase 11 involved_in ISO (PMID:19622832) BHF-UCL PMID:19622832 Ensembl chr19:1,188,537...1,210,677 JBrowse link
G TFDP1 transcription factor Dp-1 ISO (MGI:3028362|PMID:14667810) MGI PMID:14667810 MGI:3028362 NCBI chr13:94,730,343...94,789,328
Ensembl chr13:113,789,280...113,840,825
JBrowse link
G TSC2 TSC complex subunit 2 involved_in ISO (MGI:5819337|PMID:23778976)
(PMID:23778976)
ParkinsonsUK-UCL PMID:23778976 MGI:5819337 NCBI chr16:615,776...655,411
Ensembl chr16:2,135,696...2,175,569
JBrowse link
apoptotic chromosome condensation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACIN1 apoptotic chromatin condensation inducer 1 involved_in ISO (PMID:10490026) UniProt PMID:10490026 NCBI chr14:3,878,426...3,915,802
Ensembl chr14:21,975,370...22,012,092
JBrowse link
G DFFB DNA fragmentation factor subunit beta involved_in ISO (PMID:10959840) UniProt PMID:10959840 NCBI chr 1:2,529,733...2,559,490
Ensembl chr 1:3,649,729...3,676,896
JBrowse link
G ERN2 endoplasmic reticulum to nucleus signaling 2 involved_in ISO (PMID:11175748) UniProt PMID:11175748 NCBI chr16:14,397,697...14,420,618
Ensembl chr16:23,940,716...23,963,894
JBrowse link
G LOC100967334 G-protein coupled estrogen receptor 1 involved_in ISO PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr 7:1,245,873...1,251,915 JBrowse link
G TOP2A DNA topoisomerase II alpha involved_in ISO (PMID:10959840) UniProt PMID:10959840 NCBI chr17:16,872,169...16,901,605
Ensembl chr17:17,097,778...17,126,207
JBrowse link
apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DFFB DNA fragmentation factor subunit beta involved_in ISO (PMID:15572351), (PMID:22253444) RGD
CAFA
PMID:11425895 PMID:15572351 PMID:22253444 RGD:628524 NCBI chr 1:2,529,733...2,559,490
Ensembl chr 1:3,649,729...3,676,896
JBrowse link
G DNASE1L3 deoxyribonuclease 1 like 3 involved_in ISO (MGI:2385551|PMID:12050166)
(PMID:23229555)
MGI
UniProt
PMID:12050166 PMID:23229555 MGI:2385551 NCBI chr 3:58,127,491...58,146,177
Ensembl chr 3:59,542,243...59,560,363
JBrowse link
G ENDOG endonuclease G ISO (MGI:3029597|PMID:14663139) MGI PMID:14663139 MGI:3029597 NCBI chr 9:99,941,856...99,945,957 JBrowse link
G FOXL2 forkhead box L2 involved_in ISO (PMID:16153597) UniProt PMID:16153597 NCBI chr 3:135,968,040...135,980,063 JBrowse link
apoptotic mitochondrial changes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIFM2 apoptosis inducing factor mitochondria associated 2 involved_in ISO (PMID:11980907) MGI PMID:11980907 NCBI chr10:66,529,411...66,621,122
Ensembl chr10:69,114,194...69,135,267
JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO (MGI:2669068|PMID:12869584) MGI PMID:12869584 MGI:2669068 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO RGD PMID:30131474 RGD:15036798 NCBI chr12:109,343,020...109,385,060 JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in ISO (PMID:19061639) BHF-UCL PMID:19061639 Ensembl chr16:29,265,516...29,290,807 JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in ISO (MGI:2677915|PMID:12925707)
(PMID:9843949)
MGI
HGNC-UCL
PMID:9843949 PMID:12925707 MGI:2677915 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO (MGI:2686748|PMID:14707049) MGI PMID:14707049 MGI:2686748 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BID BH3 interacting domain death agonist ISO (MGI:1277505|PMID:9727492) MGI PMID:9727492 MGI:1277505 NCBI chr22:1,164,787...1,205,051
Ensembl chr22:16,594,186...16,632,844
JBrowse link
G BIK BCL2 interacting killer ISO (MGI:1202139|PMID:9525867) MGI PMID:9525867 MGI:1202139 NCBI chr22:23,994,256...24,014,244
Ensembl chr22:42,207,149...42,213,022
JBrowse link
G CD24 CD24 molecule ISO (MGI:2686748|PMID:14707049) MGI PMID:14707049 MGI:2686748 NCBI chr 6:104,783,720...104,789,509
Ensembl chr 6:108,655,624...108,657,847
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in ISO (PMID:12082630) BHF-UCL PMID:12082630 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G DAP3 death associated protein 3 ISO (MGI:1926997|PMID:11017876) MGI PMID:11017876 MGI:1926997 NCBI chr 1:131,024,977...131,072,860
Ensembl chr 1:134,876,063...134,905,280
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit ISO (MGI:3047441|PMID:15288121) MGI PMID:15288121 MGI:3047441 NCBI chr 1:96,548,850...96,573,273
Ensembl chr 1:95,278,665...95,297,893
JBrowse link
G HK2 hexokinase 2 involved_in ISO (MGI:3777889|PMID:18350175)
(PMID:18350175)
MGI PMID:18350175 MGI:3777889 NCBI chr2A:74,897,914...74,957,234
Ensembl chr2A:76,400,240...76,460,874
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:21854881 RGD:10402841 NCBI chr2B:84,729,615...84,743,352
Ensembl chr2B:202,623,497...202,636,959
JBrowse link
G JTB jumping translocation breakpoint ISO (MGI:5009395|PMID:17369841) MGI PMID:17369841 MGI:5009395 NCBI chr 1:129,331,335...129,334,873
Ensembl chr 1:132,959,843...132,963,865
JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO (MGI:3577836|PMID:15882989) MGI PMID:15882989 MGI:3577836 NCBI chr 5:57,116,405...57,197,017
Ensembl chr 5:58,745,579...58,826,959
JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member ISO (MGI:4421270|PMID:19919825) MGI PMID:19919825 MGI:4421270 NCBI chr 1:125,918,760...125,923,952
Ensembl chr 1:129,566,827...129,572,086
JBrowse link
G NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 involved_in ISO (PMID:15186778) UniProt PMID:15186778 NCBI chr2B:93,363,092...93,399,326
Ensembl chr2B:211,493,021...211,528,496
JBrowse link
G PIM2 Pim-2 proto-oncogene, serine/threonine kinase ISO (MGI:2669068|PMID:12869584) MGI PMID:12869584 MGI:2669068 NCBI chr  X:41,210,494...41,216,552
Ensembl chr  X:49,068,721...49,074,731
JBrowse link
G PPIF peptidylprolyl isomerase F ISO (MGI:3777889|PMID:18350175) MGI PMID:18350175 MGI:3777889 NCBI chr10:75,860,197...75,868,098
Ensembl chr10:78,521,642...78,530,202
JBrowse link
G PPP2CB protein phosphatase 2 catalytic subunit beta ISO (MGI:3694309|PMID:16717086) MGI PMID:16717086 MGI:3694309 NCBI chr 8:30,099,605...30,126,917
Ensembl chr 8:27,288,263...27,302,606
JBrowse link
G RNF7 ring finger protein 7 ISO (MGI:1333612|PMID:10082581) MGI PMID:10082581 MGI:1333612 NCBI chr 3:138,772,581...138,780,763
Ensembl chr 3:146,369,779...146,377,233
JBrowse link
G SLC25A4 solute carrier family 25 member 4 ISO (MGI:3777889|PMID:18350175) MGI PMID:18350175 MGI:3777889 NCBI chr 4:177,310,982...177,315,016
Ensembl chr 4:189,531,914...189,534,549
JBrowse link
G SOD2 superoxide dismutase 2 ISO (MGI:1931647|PMID:11226230) MGI PMID:11226230 MGI:1931647 NCBI chr 6:157,562,814...157,610,155
Ensembl chr 6:162,576,082...162,589,960
JBrowse link
apoptotic nuclear changes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1C activin A receptor type 1C involved_in ISO (PMID:15531507) UniProt PMID:15531507 NCBI chr2B:44,785,808...44,883,977
Ensembl chr2B:162,034,161...162,124,151
JBrowse link
G BLCAP BLCAP apoptosis inducing factor involved_in ISO (PMID:17031575) UniProt PMID:17031575 NCBI chr20:33,839,246...33,849,833
Ensembl chr20:34,954,666...34,954,929
JBrowse link
G CD24 CD24 molecule ISO (MGI:2686748|PMID:14707049) MGI PMID:14707049 MGI:2686748 NCBI chr 6:104,783,720...104,789,509
Ensembl chr 6:108,655,624...108,657,847
JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 involved_in ISO (PMID:23478299) UniProt PMID:23478299 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302
JBrowse link
G DEDD2 death effector domain containing 2 involved_in ISO (PMID:11741985) UniProt PMID:11741985 NCBI chr19:39,086,735...39,108,312
Ensembl chr19:47,678,915...47,700,431
JBrowse link
G SHARPIN SHANK associated RH domain interactor ISO (MGI:75289|PMID:7792947) MGI PMID:7792947 MGI:75289 NCBI chr 8:140,865,009...140,870,580
Ensembl chr 8:143,854,902...143,862,888
JBrowse link
apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AATK apoptosis associated tyrosine kinase ISO (MGI:1195444|PMID:9444961) MGI PMID:9444961 MGI:1195444 NCBI chr17:75,542,565...75,591,208
Ensembl chr17:81,270,707...81,319,789
JBrowse link
G ADAM15 ADAM metallopeptidase domain 15 NOT|involved_in ISO (PMID:22505472) UniProt PMID:22505472 NCBI chr 1:130,398,961...130,410,860
Ensembl chr 1:134,008,959...134,020,467
JBrowse link
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:16820859 RGD:5129152 NCBI chr10:110,642,491...110,646,595 JBrowse link
G AHCYL1 adenosylhomocysteinase like 1 involved_in ISO (PMID:27995898) UniProt PMID:27995898 NCBI chr 1:112,629,545...112,668,605 JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 involved_in ISO (PMID:23217327) UniProt PMID:23217327 NCBI chr  X:119,256,425...119,292,612
Ensembl chr  X:129,550,287...129,586,271
JBrowse link
G AKAP1 A-kinase anchoring protein 1 ISO (MGI:6432573|PMID:32072193) UniProt PMID:32072193 MGI:6432573 NCBI chr17:51,162,993...51,199,202
Ensembl chr17:56,023,381...56,058,744
JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO RGD PMID:16440211 RGD:39128200 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756
JBrowse link
G ALDOC aldolase, fructose-bisphosphate C ISO RGD PMID:16356555 RGD:2301134 NCBI chr17:28,198,895...28,202,950
Ensembl chr17:28,700,976...28,706,507
JBrowse link
G AQP2 aquaporin 2 ISO RGD PMID:18717646 RGD:2313130 NCBI chr12:38,796,300...38,804,559
Ensembl chr12:39,690,289...39,698,397
JBrowse link
G ARG2 arginase 2 ISO RGD PMID:17874066 RGD:4143285 NCBI chr14:48,197,831...48,231,829
Ensembl chr14:67,075,941...67,109,962
JBrowse link
G ATM ATM serine/threonine kinase ISO RGD PMID:10822387 RGD:1599368 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
G ATP5F1A ATP synthase F1 subunit alpha ISO RGD PMID:16215688 RGD:13703103 NCBI chr18:39,366,384...39,380,514
Ensembl chr18:42,904,136...42,923,326
JBrowse link
G BAD BCL2 associated agonist of cell death involved_in ISO (PMID:19667065) UniProt PMID:19667065 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257
JBrowse link
G BAG6 BAG cochaperone 6 involved_in ISO (PMID:14960581) UniProt PMID:14960581 NCBI chr 6:31,300,126...31,313,829
Ensembl chr 6:32,190,037...32,204,321
JBrowse link
G BAK1 BCL2 antagonist/killer 1 involved_in ISO (PMID:23028632)
(MGI:3581932|PMID:15967824)
RGD
UniProt
MGI
PMID:15967824 PMID:18817839 PMID:23028632 MGI:3581932 RGD:2313963 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211
JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in ISO (PMID:9531611)
(PMID:17428862), (PMID:9660918)
(MGI:1203837|PMID:9560217)
(MGI:1332944|PMID:10201940)
RGD
CACAO
ParkinsonsUK-UCL
MGI
PMID:9531611 PMID:9560217 PMID:9660918 PMID:10201940 PMID:11751624 PMID:16084019 PMID:17428862 PMID:18817839 PMID:18959742 MGI:1203837 MGI:1332944 RGD:1579962 RGD:2313963 RGD:2314140 RGD:70602 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BBC3 BCL2 binding component 3 involved_in ISO (PMID:26212789) ParkinsonsUK-UCL PMID:26212789 NCBI chr19:44,203,517...44,215,860 JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in ISO (PMID:36599), (PMID:8022822)
(MGI:2156164|PMID:8170972), (MGI:62849|PMID:8372353)
RGD
MGI
PMID:36599 PMID:8022822 PMID:8170972 PMID:8372353 PMID:18959742 MGI:2156164 MGI:62849 RGD:2314140 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BCL2L1 BCL2 like 1 ISO RGD PMID:18959742 RGD:2314140 NCBI chr20:27,955,688...28,015,950
Ensembl chr20:29,088,055...29,146,585
JBrowse link
G BCL2L10 BCL2 like 10 involved_in ISO (PMID:27995898) UniProt PMID:27995898 NCBI chr15:31,049,509...31,057,273 JBrowse link
G BCL2L14 BCL2 like 14 involved_in ISO (PMID:17280616) UniProt PMID:17280616 NCBI chr12:12,072,021...12,122,015
Ensembl chr12:12,444,839...12,492,777
JBrowse link
G BNIP1 BCL2 interacting protein 1 involved_in ISO (PMID:7954800) RGD
MGI
PMID:7954800 PMID:12714334 RGD:634759 NCBI chr 5:168,497,889...168,517,790
Ensembl chr 5:175,406,525...175,426,087
JBrowse link
G BNIP2 BCL2 interacting protein 2 involved_in ISO (PMID:7954800) MGI PMID:7954800 NCBI chr15:38,628,798...38,659,161
Ensembl chr15:56,933,697...56,964,044
JBrowse link
G BNIP3 BCL2 interacting protein 3 involved_in ISO (PMID:7954800) MGI PMID:7954800 NCBI chr10:128,671,663...128,685,952
Ensembl chr10:132,858,211...132,871,634
JBrowse link
G BNIPL BCL2 interacting protein like involved_in ISO (PMID:11741952) MGI PMID:11741952 NCBI chr 1:126,385,651...126,396,697 JBrowse link
G BOK BCL2 family apoptosis regulator BOK involved_in ISO PMID:9356461
(PMID:15102863)
UniProt PMID:9356461 PMID:15102863 RGD:70678 NCBI chr2B:128,832,458...128,847,918
Ensembl chr2B:247,626,494...247,640,238
JBrowse link
G BRAT1 BRCA1 associated ATM activator 1 involved_in ISO (PMID:25070371) UniProt PMID:25070371 NCBI chr 7:2,797,551...2,815,847
Ensembl chr 7:2,892,302...2,910,143
JBrowse link
G C19H19orf12 chromosome 19 C19orf12 homolog involved_in ISO (PMID:26136767) UniProt PMID:26136767 NCBI chr19:26,626,994...26,643,372
Ensembl chr19:35,385,884...35,401,408
JBrowse link
G C5AR1 complement C5a receptor 1 ISO RGD PMID:18648551 RGD:5130170 NCBI chr19:44,293,612...44,310,430
Ensembl chr19:52,950,317...52,966,146
JBrowse link
G CASP1 caspase 1 ISO RGD PMID:11404793 RGD:631309 NCBI chr11:99,965,964...99,975,640
Ensembl chr11:103,448,497...103,458,149
JBrowse link
G CASP2 caspase 2 ISO RGD PMID:18614702 RGD:4107075 NCBI chr 7:135,283,072...135,307,855
Ensembl chr 7:147,773,749...147,792,958
JBrowse link
G CASP3 caspase 3 involved_in ISO (PMID:15565177)
(MGI:2159507|PMID:9512515), (MGI:2677082|PMID:12970760)
(MGI:3615714|PMID:16469926)
(MGI:2667259|PMID:12847083), (MGI:3770607|PMID:17901126)
RGD
UniProt
MGI
PMID:9512515 PMID:12847083 PMID:12970760 PMID:15565177 PMID:16469926 PMID:17901126 PMID:18817839 MGI:2159507 MGI:2667259 MGI:2677082 MGI:3615714 MGI:3770607 RGD:2313963 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185
JBrowse link
G CASP7 caspase 7 involved_in ISO (MGI:3615714|PMID:16469926)
(PMID:17464193)
MGI
UniProt
PMID:16469926 PMID:17464193 MGI:3615714 NCBI chr10:110,273,318...110,324,800
Ensembl chr10:113,707,780...113,758,626
JBrowse link
G CASP8 caspase 8 involved_in ISO (PMID:22891283)
(PMID:17599062)
(MGI:3603971|PMID:16183742)
RGD
UniProt
MGI
PMID:11841995 PMID:16183742 PMID:17599062 PMID:22891283 MGI:3603971 RGD:632452 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468
JBrowse link
G CASP9 caspase 9 involved_in ISO (PMID:15069058)
(MGI:3615714|PMID:16469926)
(MGI:2667259|PMID:12847083), (MGI:3770607|PMID:17901126)
RGD
UniProt
MGI
PMID:12847083 PMID:15069058 PMID:16469926 PMID:17901126 PMID:18817839 MGI:2667259 MGI:3615714 MGI:3770607 RGD:2313963 NCBI chr 1:14,630,659...14,662,865
Ensembl chr 1:15,624,666...15,656,266
JBrowse link
G CASR calcium sensing receptor ISO RGD PMID:20409080 RGD:7206835 NCBI chr 3:119,278,071...119,383,901
Ensembl chr 3:126,252,765...126,285,268
JBrowse link
G CCK cholecystokinin ISO RGD PMID:11964411 RGD:625521 NCBI chr 3:42,168,012...42,176,358
Ensembl chr 3:42,431,022...42,439,396
JBrowse link
G CCKBR cholecystokinin B receptor ISO RGD PMID:17088981 RGD:2311330 NCBI chr11:6,393,435...6,405,821
Ensembl chr11:6,075,816...6,088,145
JBrowse link
G CDIP1 cell death inducing p53 target 1 involved_in ISO (PMID:17599062) MGI PMID:17599062 NCBI chr16:3,437,414...3,464,989
Ensembl chr16:4,604,954...4,632,724
JBrowse link
G CDK5 cyclin dependent kinase 5 ISO (MGI:87730|PMID:9126296) MGI PMID:9126296 MGI:87730 NCBI chr 7:142,640,630...142,644,785
Ensembl chr 7:154,793,344...154,797,499
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator involved_in ISO (PMID:21737330) UniProt PMID:21737330 NCBI chr2B:88,373,057...88,429,959
Ensembl chr2B:206,528,943...206,577,045
JBrowse link
G CHEK1 checkpoint kinase 1 involved_in ISO (PMID:23028632) UniProt PMID:23028632 NCBI chr11:120,446,352...120,478,207 JBrowse link
G CHEK2 checkpoint kinase 2 ISO (MGI:3805397|PMID:18614044) MGI PMID:18614044 MGI:3805397 NCBI chr22:9,757,038...9,811,171 JBrowse link
G CIB1 calcium and integrin binding 1 involved_in ISO (PMID:10366599) HGNC-UCL PMID:10366599 NCBI chr15:68,919,377...68,923,213 JBrowse link
G CIDEC cell death inducing DFFA like effector c involved_in ISO (PMID:12429024) MGI PMID:12429024 NCBI chr 3:9,811,995...9,836,069
Ensembl chr 3:10,048,554...10,173,107
JBrowse link
G COMP cartilage oligomeric matrix protein ISO (MGI:3723532|PMID:17588960) MGI PMID:17588960 MGI:3723532 NCBI chr19:18,222,270...18,230,936
Ensembl chr19:19,229,562...19,238,008
JBrowse link
G CST3 cystatin C ISO RGD PMID:16414118 RGD:2306496 NCBI chr20:23,583,043...23,587,399
Ensembl chr20:23,935,942...23,940,425
JBrowse link
G CUL1 cullin 1 ISO (MGI:1345782|PMID:10508527) MGI PMID:10508527 MGI:1345782 NCBI chr 7:140,428,442...140,531,136
Ensembl chr 7:152,908,303...153,011,254
JBrowse link
G CYFIP2 cytoplasmic FMR1 interacting protein 2 involved_in ISO (PMID:10449408) UniProt PMID:10449408 NCBI chr 5:152,667,136...152,796,575
Ensembl chr 5:159,292,029...159,418,077
JBrowse link
G DAP death associated protein involved_in ISO (PMID:7828849) MGI PMID:7828849 NCBI chr 5:10,991,599...11,078,154
Ensembl chr 5:10,846,394...10,927,869
JBrowse link
G DAPK1 death associated protein kinase 1 involved_in ISO (PMID:7828849)
(PMID:10629061)
MGI
UniProt
PMID:7828849 PMID:10629061 NCBI chr 9:58,628,872...58,836,205
Ensembl chr 9:86,681,953...86,887,958
JBrowse link
G DAPK3 death associated protein kinase 3 involved_in ISO PMID:10602480
(PMID:12917339)
(PMID:10580117)
UniProt PMID:10580117 PMID:10602480 PMID:12917339 RGD:8554171 NCBI chr19:2,984,806...2,996,782
Ensembl chr19:3,934,496...3,946,011
JBrowse link
G DDIT3 DNA damage inducible transcript 3 ISO (MGI:5448503|PMID:22265908) UniProt PMID:22265908 MGI:5448503 NCBI chr12:31,406,332...31,410,293
Ensembl chr12:31,664,743...31,668,701
JBrowse link
G DDIT4 DNA damage inducible transcript 4 ISO RGD PMID:11884613 RGD:633979 NCBI chr10:68,796,712...68,798,840
Ensembl chr10:71,264,029...71,266,149
JBrowse link
G DIO3 iodothyronine deiodinase 3 ISO (MGI:4441081|PMID:20203194) MGI PMID:20203194 MGI:4441081 NCBI chr14:82,188,126...82,190,220 JBrowse link
G DLC1 DLC1 Rho GTPase activating protein involved_in ISO (PMID:17292327) UniProt PMID:17292327 NCBI chr 8:12,282,190...12,809,770
Ensembl chr 8:9,037,742...9,460,233
JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 ISO (MGI:3612004|PMID:16327803) MGI PMID:16327803 MGI:3612004 NCBI chr16:3,351,825...3,381,914
Ensembl chr16:4,519,965...4,550,786
JBrowse link
G ECE1 endothelin converting enzyme 1 ISO RGD PMID:15733912 RGD:1581735 NCBI chr 1:20,166,019...20,290,803
Ensembl chr 1:21,206,199...21,278,909
JBrowse link
G EFNA5 ephrin A5 NOT|involved_in ISO (PMID:11870224) UniProt PMID:11870224 NCBI chr 5:102,732,268...103,026,746
Ensembl chr 5:108,548,927...108,598,942
JBrowse link
G EGLN3 egl-9 family hypoxia inducible factor 3 involved_in ISO (PMID:20978507) UniProt PMID:20978507 NCBI chr14:14,689,398...14,716,301
Ensembl chr14:32,880,324...32,907,241
JBrowse link
G EIF5A eukaryotic translation initiation factor 5A involved_in ISO (PMID:15371445), (PMID:17187778) UniProt PMID:15371445 PMID:17187778 NCBI chr17:7,341,076...7,346,570
Ensembl chr17:7,327,363...7,333,270
JBrowse link
G EP300 E1A binding protein p300 involved_in ISO (PMID:9194565) UniProt PMID:9194565 NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604
JBrowse link
G EPO erythropoietin ISO (MGI:3762687|PMID:17300687) MGI PMID:17300687 MGI:3762687 NCBI chr 7:92,747,671...92,750,886
Ensembl chr 7:106,148,062...106,150,974
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit involved_in ISO (PMID:8675009) UniProt PMID:8675009 NCBI chr19:42,298,927...42,319,816
Ensembl chr19:50,897,004...50,915,819
JBrowse link
G ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit involved_in ISO (PMID:8675009) UniProt PMID:8675009 NCBI chr2B:32,983,492...33,020,492
Ensembl chr2B:127,922,483...127,959,372
JBrowse link
G FADD Fas associated via death domain involved_in ISO (PMID:22891283) UniProt PMID:22891283 NCBI chr11:65,300,889...65,305,020 JBrowse link
G FAS Fas cell surface death receptor involved_in ISO (MGI:81811|PMID:8700551)
(PMID:9681877)
MGI PMID:8700551 PMID:9681877 MGI:81811 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G FASTKD2 FAST kinase domains 2 involved_in ISO (PMID:18771761) UniProt PMID:18771761 NCBI chr2B:93,999,837...94,030,683
Ensembl chr2B:212,129,283...212,154,329
JBrowse link
G FGF13 fibroblast growth factor 13 NOT ISO (MGI:5431268|PMID:22726441) UniProt PMID:22726441 MGI:5431268 NCBI chr  X:127,764,648...128,353,928 JBrowse link
G FOXO1 forkhead box O1 involved_in ISO (PMID:31063815) UniProt PMID:31063815 NCBI chr13:21,763,729...21,874,279 JBrowse link
G FOXO3 forkhead box O3 ISO RGD PMID:19258007 RGD:10402200 NCBI chr 6:106,360,519...106,485,676
Ensembl chr 6:110,406,266...110,516,272
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase ISO RGD PMID:10424669 RGD:632777 NCBI chr12:6,665,218...6,669,170
Ensembl chr12:6,583,895...6,587,729
JBrowse link
G GJA1 gap junction protein alpha 1 ISO RGD PMID:17107662 RGD:1601339 NCBI chr 6:119,213,513...119,227,617 JBrowse link
G GJB6 gap junction protein beta 6 ISO RGD PMID:12359154 RGD:632751 NCBI chr13:1,549,089...1,559,452
Ensembl chr13:19,864,939...19,865,724
JBrowse link
G GPX1 glutathione peroxidase 1 ISO (MGI:3662803|PMID:16934683), (MGI:3662804|PMID:16962942) MGI PMID:16934683 PMID:16962942 MGI:3662803 MGI:3662804 NCBI chr 3:49,280,038...49,281,455
Ensembl chr 3:50,360,947...50,361,826
JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist ISO RGD PMID:9234736 RGD:69808 NCBI chr15:11,213,870...11,230,619 JBrowse link
G GSDMA gasdermin A involved_in ISO (PMID:17471240) UniProt PMID:17471240 NCBI chr17:17,311,932...17,324,004
Ensembl chr17:17,531,767...17,543,413
JBrowse link
G GSN gelsolin ISO RGD PMID:10698078 RGD:1599868 NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831
JBrowse link
G HIP1 huntingtin interacting protein 1 involved_in ISO (PMID:11788820) MGI PMID:11788820 NCBI chr 7:68,281,899...68,464,233 JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO RGD PMID:14988264 RGD:1358731 NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078
JBrowse link
G HRK harakiri, BCL2 interacting protein ISO RGD PMID:10075695 RGD:70327 NCBI chr12:114,432,755...114,458,044 JBrowse link
G IFI27 interferon alpha inducible protein 27 involved_in ISO (PMID:18330707)
(PMID:27673746)
UniProt PMID:18330707 PMID:27673746 NCBI chr14:74,742,775...74,748,820
Ensembl chr14:94,046,694...94,082,022
JBrowse link
G IFI27L1 interferon alpha inducible protein 27 like 1 involved_in ISO (PMID:27673746) UniProt PMID:27673746 NCBI chr14:74,713,459...74,734,835 JBrowse link
G IFI27L2 interferon alpha inducible protein 27 like 2 involved_in ISO (PMID:27673746) UniProt PMID:27673746 NCBI chr14:74,759,874...74,761,850 JBrowse link
G IFI6 interferon alpha inducible protein 6 involved_in ISO (PMID:27673746) UniProt PMID:27673746 NCBI chr 1:26,929,129...26,935,205
Ensembl chr 1:27,972,866...27,978,890
JBrowse link
G IFNG interferon gamma involved_in ISO (PMID:7828849) MGI PMID:7828849 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G IFT57 intraflagellar transport 57 involved_in ISO (PMID:11788820) MGI PMID:11788820 NCBI chr 3:105,287,086...105,348,872
Ensembl chr 3:112,222,128...112,282,069
JBrowse link
G ING4 inhibitor of growth family member 4 involved_in ISO (PMID:15251430) UniProt PMID:15251430 NCBI chr12:6,782,402...6,795,035
Ensembl chr12:6,698,843...6,710,955
JBrowse link
G IRF1 interferon regulatory factor 1 involved_in ISO (PMID:19851330) UniProt PMID:19851330 NCBI chr 5:127,903,887...127,913,843
Ensembl chr 5:134,067,441...134,075,035
JBrowse link
G KAT5 lysine acetyltransferase 5 ISO RGD PMID:11416127 RGD:9588319 NCBI chr11:61,071,118...61,078,667
Ensembl chr11:64,404,572...64,412,667
JBrowse link
G KREMEN1 kringle containing transmembrane protein 1 ISO (MGI:5883198|PMID:26206087) UniProt PMID:26206087 MGI:5883198 NCBI chr22:10,128,326...10,202,548
Ensembl chr22:27,828,011...28,031,917
JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase ISO RGD PMID:7930951 RGD:1600237 NCBI chr 1:31,560,229...31,572,391
Ensembl chr 1:32,565,739...32,579,923
JBrowse link
G LMNB1 lamin B1 ISO RGD PMID:20204270 RGD:10044249 NCBI chr 5:122,179,513...122,240,848
Ensembl chr 5:127,949,457...128,010,721
JBrowse link
G LOC100986481 cytochrome c ISO (MGI:3652666|PMID:16757556) RGD
MGI
PMID:16757556 PMID:18817839 MGI:3652666 RGD:2313963 NCBI chr 7:25,784,900...25,791,598
Ensembl chr 7:25,396,013...25,398,549
JBrowse link
G MAP2K6 mitogen-activated protein kinase kinase 6 ISO RGD PMID:17007737 RGD:1582278 NCBI chr17:63,342,720...63,483,926
Ensembl chr17:68,730,011...68,870,454
JBrowse link
G MAPT microtubule associated protein tau ISO RGD PMID:15750210 RGD:1599925 NCBI chr17:11,373,220...11,506,669
Ensembl chr17:11,458,159...11,523,129
JBrowse link
G MCM2 minichromosome maintenance complex component 2 involved_in ISO (PMID:26196677) UniProt PMID:26196677 NCBI chr 3:124,643,362...124,667,121
Ensembl chr 3:131,950,887...131,974,641
JBrowse link
G MDM2 MDM2 proto-oncogene involved_in ISO (MGI:6303570|PMID:30879903)
(PMID:30879903)
UniProt PMID:30879903 MGI:6303570 NCBI chr12:66,322,340...66,357,010
Ensembl chr12:69,102,084...69,133,278
JBrowse link
G MELK maternal embryonic leucine zipper kinase involved_in ISO (PMID:17280616) UniProt PMID:17280616 NCBI chr 9:36,419,974...36,522,584
Ensembl chr 9:37,219,170...37,321,318
JBrowse link
G MTFP1 mitochondrial fission process 1 ISO (MGI:6276530|PMID:30325740) MGI PMID:30325740 MGI:6276530 NCBI chr22:11,461,119...11,464,739
Ensembl chr22:29,262,118...29,265,700
JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming ISO (MGI:2159585|PMID:11872843) MGI PMID:11872843 MGI:2159585 NCBI chr11:1,106,716...1,144,489
Ensembl chr11:1,143,625...1,169,741
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in ISO (PMID:22155231) AgBase PMID:22155231 NCBI chr 3:38,036,565...38,041,014
Ensembl chr 3:38,319,024...38,323,572
JBrowse link
G NCF1 neutrophil cytosolic factor 1 ISO RGD PMID:16344068 RGD:1600568 Ensembl chr 7:81,917,167...81,932,589 JBrowse link
G NHLH2 nescient helix-loop-helix 2 ISO (MGI:3723363|PMID:17573818) UniProt PMID:17573818 MGI:3723363 NCBI chr 1:86,719,650...86,727,607
Ensembl chr 1:121,774,940...121,775,347
JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 ISO (MGI:3721333|PMID:17434920) MGI PMID:17434920 MGI:3721333 NCBI chr12:36,703,903...36,740,211
Ensembl chr12:37,480,300...37,501,188
JBrowse link
G NSG1 neuronal vesicle trafficking associated 1 involved_in ISO (PMID:20599942) UniProt PMID:20599942 Ensembl chr 4:4,467,234...4,496,088 JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in ISO (PMID:20824293) UniProt PMID:20824293 NCBI chr  X:60,798,219...60,840,948
Ensembl chr  X:70,852,687...70,894,921
JBrowse link
G PAEP progestagen associated endometrial protein involved_in ISO (PMID:18996219) CACAO PMID:18996219 NCBI chr 9:106,669,550...106,681,918 JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:15565177) UniProt PMID:15565177 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO PMID:16229834 RGD
UniProt
PMID:16229834 PMID:17219052 RGD:8554822 RGD:9835345 NCBI chr12:77,114,282...77,224,116
Ensembl chr12:79,969,517...80,070,796
JBrowse link
G PDCD6 programmed cell death 6 ISO (MGI:81240|PMID:8560270) MGI PMID:8560270 MGI:81240 NCBI chr 5:250,025...291,055 JBrowse link
G PIDD1 p53-induced death domain protein 1 involved_in ISO (PMID:17159900) UniProt PMID:17159900 NCBI chr11:816,629...827,295
Ensembl chr11:860,899...867,436
JBrowse link
G PLSCR1 phospholipid scramblase 1 involved_in ISO (PMID:10770950) UniProt PMID:10770950 NCBI chr 3:143,528,967...143,558,468
Ensembl chr 3:151,112,483...151,132,964
JBrowse link
G PLSCR3 phospholipid scramblase 3 involved_in ISO (MGI:6436981|PMID:21785166)
(PMID:12649167)
UniProt PMID:12649167 PMID:21785166 MGI:6436981 NCBI chr17:7,423,903...7,429,026
Ensembl chr17:7,410,668...7,414,409
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:17599062) RGD
MGI
PMID:17599062 PMID:18959742 RGD:2314140 NCBI chr18:53,286,590...53,290,913
Ensembl chr18:56,611,098...56,615,449
JBrowse link
G PML PML nuclear body scaffold involved_in ISO (PMID:9583681) UniProt PMID:9583681 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883
JBrowse link
G POLB DNA polymerase beta ISO (MGI:5553198|PMID:24388753) MGI PMID:24388753 MGI:5553198 NCBI chr 8:41,582,370...41,615,950
Ensembl chr 8:39,026,991...39,060,464
JBrowse link
G POLR2G RNA polymerase II subunit G ISO RGD PMID:17356516 RGD:2303047 NCBI chr11:58,116,833...58,122,031
Ensembl chr11:61,470,866...61,476,073
JBrowse link
G PPARD peroxisome proliferator activated receptor delta involved_in ISO (PMID:12909723) CACAO PMID:12909723 NCBI chr 6:34,903,798...34,987,208
Ensembl chr 6:36,003,988...36,081,132
JBrowse link
G PPIA peptidylprolyl isomerase A involved_in ISO (PMID:15130913)
(PMID:31063815)
UniProt PMID:15130913 PMID:31063815 NCBI chr 7:45,510,450...45,515,448
Ensembl chr 7:45,578,765...45,605,545
JBrowse link
G PRF1 perforin 1 ISO RGD PMID:15843543 RGD:6482825 NCBI chr10:67,071,141...67,078,057
Ensembl chr10:69,597,574...69,603,070
JBrowse link
G PRKCD protein kinase C delta involved_in ISO PMID:21696630
(PMID:10770950), (PMID:12649167)
CACAO
UniProt
PMID:10770950 PMID:12649167 PMID:21696630 RGD:10047294 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910
JBrowse link
G RELT RELT TNF receptor involved_in ISO (PMID:16530727), (PMID:28688764) UniProt PMID:16530727 PMID:28688764 NCBI chr11:68,453,109...68,474,262
Ensembl chr11:71,673,955...71,695,103
JBrowse link
G RFK riboflavin kinase involved_in ISO (PMID:19641494) MGI PMID:19641494 NCBI chr 9:48,447,295...48,456,262
Ensembl chr 9:75,245,636...75,254,350
JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in ISO (MGI:5926457|PMID:28842570), (MGI:6120592|PMID:29440439), (MGI:6362112|PMID:31519886), (MGI:6362574|PMID:31519887), (MGI:6369186|PMID:30867408), (MGI:6378798|PMID:31511692)
(PMID:21737330), (PMID:22891283), (PMID:29440439)
UniProt PMID:21737330 PMID:22891283 PMID:28842570 PMID:29440439 PMID:30867408 PMID:31511692 PMID:31519886 PMID:31519887 MGI:5926457 MGI:6120592 MGI:6362112 MGI:6362574 MGI:6369186 MGI:6378798 NCBI chr 6:2,893,802...2,943,162
Ensembl chr 6:2,997,343...3,045,078
JBrowse link
G SCML2 Scm polycomb group protein like 2 ISO (MGI:5645866|PMID:25634095) MGI PMID:25634095 MGI:5645866 NCBI chr  X:10,862,608...10,977,851
Ensembl chr  X:18,226,256...18,344,155
JBrowse link
G SEMA3A semaphorin 3A ISO RGD PMID:12376549 RGD:729827 NCBI chr 7:75,929,699...76,484,246
Ensembl chr 7:89,590,359...90,004,122
JBrowse link
G SFRP2 secreted frizzled related protein 2 ISO (MGI:3806414|PMID:18729207) MGI PMID:18729207 MGI:3806414 NCBI chr 4:146,123,075...146,131,543
Ensembl chr 4:157,944,733...157,953,258
JBrowse link
G SHC4 SHC adaptor protein 4 ISO (MGI:5474441|PMID:22948967) MGI PMID:22948967 MGI:5474441 NCBI chr15:27,773,442...27,913,790
Ensembl chr15:46,098,526...46,236,533
JBrowse link
G STK17B serine/threonine kinase 17b ISO PMID:11481038 UniProt PMID:11481038 RGD:634154 NCBI chr2B:83,384,562...83,422,642
Ensembl chr2B:201,285,119...201,323,314
JBrowse link
G STK4 serine/threonine kinase 4 involved_in ISO (PMID:21212262) UniProt PMID:21212262 NCBI chr20:41,297,157...41,410,487
Ensembl chr20:42,389,615...42,503,014
JBrowse link
G TAF10 TATA-box binding protein associated factor 10 ISO (MGI:1344821|PMID:10469660) MGI PMID:10469660 MGI:1344821 NCBI chr11:6,742,862...6,744,260 JBrowse link
G TCHP trichoplein keratin filament binding involved_in ISO (PMID:18931701) UniProt PMID:18931701 NCBI chr12:107,476,176...107,494,035
Ensembl chr12:110,873,883...110,889,104
JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 ISO (MGI:5488585|PMID:21305608)
(MGI:6296816|PMID:23908015)
MGI PMID:21305608 PMID:23908015 MGI:5488585 MGI:6296816 NCBI chr11:63,120,913...63,132,831
Ensembl chr11:66,429,435...66,441,327
JBrowse link
G TFPT TCF3 fusion partner ISO PMID:16229834 UniProt PMID:16229834 RGD:8554822 NCBI chr19:51,039,142...51,048,346
Ensembl chr19:59,879,141...59,891,335
JBrowse link
G TGFB1 transforming growth factor beta 1 NOT|involved_in ISO (PMID:3470709) UniProt PMID:3470709 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in ISO (PMID:17471240) UniProt PMID:17471240 NCBI chr 3:30,536,187...30,623,653
Ensembl chr 3:30,854,460...30,938,856
JBrowse link
G THOC1 THO complex 1 involved_in ISO (PMID:10512864) UniProt PMID:10512864 NCBI chr18:14,052,858...14,102,559
Ensembl chr18:17,692,797...17,742,570
JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 ISO RGD PMID:11751455 RGD:10043305 NCBI chr21:17,483,273...17,925,301
Ensembl chr21:30,868,308...31,016,883
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:12077131 RGD:625484 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TNFRSF21 TNF receptor superfamily member 21 involved_in ISO (PMID:22761420) UniProt PMID:22761420 NCBI chr 6:46,815,762...46,894,286
Ensembl chr 6:48,079,749...48,158,356
JBrowse link
G TOPAZ1 testis and ovary specific PAZ domain containing 1 ISO (MGI:5697228|PMID:26358182) MGI PMID:26358182 MGI:5697228 NCBI chr 3:44,131,729...44,221,846
Ensembl chr 3:45,190,960...45,280,601
JBrowse link
G TP53 tumor protein p53 ISO (MGI:3603971|PMID:16183742)
(MGI:3709911|PMID:17325035)
MGI PMID:16183742 PMID:17325035 MGI:3603971 MGI:3709911 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G TRAF7 TNF receptor associated factor 7 involved_in ISO (PMID:15001576) MGI PMID:15001576 NCBI chr16:1,013,831...1,036,486
Ensembl chr16:2,266,194...2,279,031
JBrowse link
G TRPV2 transient receptor potential cation channel subfamily V member 2 NOT ISO (MGI:4442533|PMID:20357111) DFLAT PMID:20357111 MGI:4442533 NCBI chr17:35,329,283...35,350,729
Ensembl chr2A:110,620,793...110,642,926
JBrowse link
G UMOD uromodulin ISO (MGI:6094531|PMID:29145399) MGI PMID:29145399 MGI:6094531 NCBI chr16:17,960,456...17,980,338
Ensembl chr16:20,430,085...20,449,121
JBrowse link
G USP53 ubiquitin specific peptidase 53 ISO (MGI:5703670|PMID:26609154) MGI PMID:26609154 MGI:5703670 NCBI chr 4:111,407,037...111,483,541
Ensembl chr 4:121,984,659...122,031,531
JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in ISO (PMID:25296756) UniProt PMID:25296756 NCBI chr 5:129,375,267...129,408,230
Ensembl chr 5:135,529,173...135,560,005
JBrowse link
G WT1 WT1 transcription factor ISO (MGI:3612377|PMID:16418481) MGI PMID:16418481 MGI:3612377 NCBI chr11:32,349,807...32,398,494
Ensembl chr11:32,238,720...32,287,249
JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 ISO (MGI:3047495|PMID:15226444) MGI PMID:15226444 MGI:3047495 NCBI chr14:49,372,058...49,379,116
Ensembl chr14:68,247,347...68,255,805
JBrowse link
G ZNF385A zinc finger protein 385A ISO (MGI:5508602|PMID:17719541) UniProt PMID:17719541 MGI:5508602 NCBI chr12:34,353,975...34,376,172
Ensembl chr12:35,080,820...35,102,248
JBrowse link
apoptotic process in bone marrow cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2L1 BCL2 like 1 ISO (MGI:1351384|PMID:10618441) MGI PMID:10618441 MGI:1351384 NCBI chr20:27,955,688...28,015,950
Ensembl chr20:29,088,055...29,146,585
JBrowse link
apoptotic process involved in blood vessel morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAK1 BCL2 antagonist/killer 1 ISO (MGI:3692135|PMID:15955981) MGI PMID:15955981 MGI:3692135 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211
JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO (MGI:3692135|PMID:15955981) MGI PMID:15955981 MGI:3692135 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G LEF1 lymphoid enhancer binding factor 1 ISO (MGI:3604165|PMID:16163358) MGI PMID:16163358 MGI:3604165 NCBI chr 4:100,552,959...100,674,156
Ensembl chr 4:111,125,312...111,245,980
JBrowse link
G LRP5 LDL receptor related protein 5 ISO (MGI:3604165|PMID:16163358) MGI PMID:16163358 MGI:3604165 NCBI chr11:63,396,511...63,534,471
Ensembl chr11:66,735,246...66,839,817
JBrowse link
G SPI1 Spi-1 proto-oncogene ISO (MGI:3604165|PMID:16163358) MGI PMID:16163358 MGI:3604165 NCBI chr11:47,301,245...47,326,891
Ensembl chr11:47,853,991...47,880,259
JBrowse link
G WNT7B Wnt family member 7B ISO (MGI:3604165|PMID:16163358) MGI PMID:16163358 MGI:3604165 Ensembl chr22:44,988,647...45,044,841 JBrowse link
apoptotic process involved in development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHEK1 checkpoint kinase 1 ISO (MGI:1860048|PMID:10859163) MGI PMID:10859163 MGI:1860048 NCBI chr11:120,446,352...120,478,207 JBrowse link
G MEGF10 multiple EGF like domains 10 ISO (MGI:5775214|PMID:27170117) MGI PMID:27170117 MGI:5775214 NCBI chr 5:122,639,155...122,877,324
Ensembl chr 5:128,466,095...128,641,043
JBrowse link
G SIX3 SIX homeobox 3 ISO (MGI:3813369|PMID:18694563) UniProt PMID:18694563 MGI:3813369 NCBI chr2A:45,038,634...45,072,867 JBrowse link
G ZPR1 ZPR1 zinc finger ISO (MGI:3575865|PMID:15767679) UniProt PMID:15767679 MGI:3575865 NCBI chr11:111,613,940...111,623,539
Ensembl chr11:115,547,973...115,557,883
JBrowse link
apoptotic process involved in embryonic digit morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator ISO (MGI:3581932|PMID:15967824) MGI PMID:15967824 MGI:3581932 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BCL2L11 BCL2 like 11 ISO (MGI:3581932|PMID:15967824) MGI PMID:15967824 MGI:3581932 NCBI chr2A:90,862,070...90,909,833
Ensembl chr2A:112,337,927...112,385,079
JBrowse link
G NOTCH1 notch receptor 1 ISO (MGI:3608163|PMID:16245338) MGI PMID:16245338 MGI:3608163 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740
JBrowse link
apoptotic process involved in endocardial cushion morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 NOT ISO (MGI:3814273|PMID:18924235) BHF-UCL PMID:18924235 MGI:3814273 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
apoptotic process involved in heart morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCN1 cellular communication network factor 1 ISO (MGI:3761425|PMID:17023674) MGI PMID:17023674 MGI:3761425 NCBI chr 1:118,138,739...118,141,681
Ensembl chr 1:86,994,296...86,997,147
JBrowse link
G HAND2 heart and neural crest derivatives expressed 2 ISO (MGI:2153294|PMID:11784028) MGI PMID:11784028 MGI:2153294 NCBI chr 4:165,755,000...165,758,735 JBrowse link
G NKX2-5 NK2 homeobox 5 ISO (MGI:3773736|PMID:16510504) MGI PMID:16510504 MGI:3773736 NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514
JBrowse link
apoptotic process involved in luteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ROBO2 roundabout guidance receptor 2 involved_in ISO (PMID:18566128) UniProt PMID:18566128 NCBI chr 3:76,013,780...77,764,156
Ensembl chr 3:79,030,223...79,632,309
JBrowse link
G SLIT2 slit guidance ligand 2 involved_in ISO (PMID:18566128) UniProt PMID:18566128 NCBI chr 4:14,654,448...15,023,708
Ensembl chr 4:20,158,952...20,314,656
JBrowse link
G SLIT3 slit guidance ligand 3 involved_in ISO (PMID:18566128) UniProt PMID:18566128 NCBI chr 5:164,029,432...164,664,156
Ensembl chr 5:170,793,731...171,425,242
JBrowse link
apoptotic process involved in morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRYAB crystallin alpha B ISO (MGI:3617146|PMID:16439475) MGI PMID:16439475 MGI:3617146 NCBI chr11:106,795,406...106,800,019
Ensembl chr11:110,639,442...110,644,272
JBrowse link
G FGF4 fibroblast growth factor 4 ISO (MGI:3530724|PMID:15649466) MGI PMID:15649466 MGI:3530724 NCBI chr11:64,866,649...64,871,031 JBrowse link
G FZD5 frizzled class receptor 5 ISO (MGI:3821812|PMID:18791178) MGI PMID:18791178 MGI:3821812 NCBI chr2B:95,003,246...95,010,577
Ensembl chr2B:213,133,017...213,134,774
JBrowse link
G LEF1 lymphoid enhancer binding factor 1 ISO (MGI:3530724|PMID:15649466) MGI PMID:15649466 MGI:3530724 NCBI chr 4:100,552,959...100,674,156
Ensembl chr 4:111,125,312...111,245,980
JBrowse link
G PPP2R1B protein phosphatase 2 scaffold subunit Abeta involved_in ISO (PMID:21172653) UniProt PMID:21172653 NCBI chr11:106,609,754...106,651,811
Ensembl chr11:110,465,475...110,495,908
JBrowse link
G SCRIB scribble planar cell polarity protein involved_in ISO (PMID:19041750) UniProt PMID:19041750 NCBI chr 8:140,544,797...140,571,078
Ensembl chr 8:143,557,722...143,582,353
JBrowse link
apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA6 annexin A6 ISO (MGI:5485084|PMID:23341998) CACAO PMID:23341998 MGI:5485084 NCBI chr 5:146,528,446...146,585,186
Ensembl chr 5:152,530,445...152,652,231
JBrowse link
G BAD BCL2 associated agonist of cell death ISO (MGI:2158953|PMID:11717309), (MGI:3057092|PMID:15231831)
(MGI:2671672|PMID:12931191)
MGI PMID:11717309 PMID:12931191 PMID:15231831 MGI:2158953 MGI:2671672 MGI:3057092 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257
JBrowse link
G BAK1 BCL2 antagonist/killer 1 involved_in ISO (PMID:15901672) UniProt PMID:15901672 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211
JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in ISO (MGI:2676517|PMID:14507967), (MGI:2677915|PMID:12925707)
(PMID:16424160)
MGI
HGNC-UCL
PMID:12925707 PMID:14507967 PMID:16424160 MGI:2676517 MGI:2677915 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BBC3 BCL2 binding component 3 involved_in ISO (PMID:11463392) UniProt PMID:11463392 NCBI chr19:44,203,517...44,215,860 JBrowse link
G CASP2 caspase 2 ISO (MGI:2450211|PMID:12477715), (MGI:3603971|PMID:16183742) MGI PMID:12477715 PMID:16183742 MGI:2450211 MGI:3603971 NCBI chr 7:135,283,072...135,307,855
Ensembl chr 7:147,773,749...147,792,958
JBrowse link
G CASP8 caspase 8 involved_in ISO (MGI:3603971|PMID:16183742)
(PMID:11101870)
MGI
BHF-UCL
PMID:11101870 PMID:16183742 MGI:3603971 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468
JBrowse link
G CAV1 caveolin 1 involved_in ISO (PMID:21382479) UniProt PMID:21382479 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G CD24 CD24 molecule ISO (MGI:2686748|PMID:14707049), (MGI:3757615|PMID:8920854), (MGI:3757616|PMID:8943715) MGI PMID:8920854 PMID:8943715 PMID:14707049 MGI:2686748 MGI:3757615 MGI:3757616 NCBI chr 6:104,783,720...104,789,509
Ensembl chr 6:108,655,624...108,657,847
JBrowse link
G CD28 CD28 molecule ISO (MGI:1340173|PMID:10429671) MGI PMID:10429671 MGI:1340173 NCBI chr2B:90,938,795...90,971,438
Ensembl chr2B:209,076,388...209,111,213
JBrowse link
G CD3E CD3e molecule ISO (MGI:80946|PMID:8666928) MGI PMID:8666928 MGI:80946 NCBI chr11:113,142,200...113,153,928
Ensembl chr11:117,074,041...117,085,625
JBrowse link
G CD5 CD5 molecule ISO (MGI:1340173|PMID:10429671) MGI PMID:10429671 MGI:1340173 NCBI chr11:56,362,415...56,388,469
Ensembl chr11:59,801,808...59,826,448
JBrowse link
G CRADD CASP2 and RIPK1 domain containing adaptor with death domain involved_in ISO (PMID:8985253) UniProt PMID:8985253 NCBI chr12:91,220,813...91,593,799 JBrowse link
G DAP death associated protein involved_in ISO (PMID:1087798), (PMID:7828849) UniProt PMID:1087798 PMID:7828849 NCBI chr 5:10,991,599...11,078,154
Ensembl chr 5:10,846,394...10,927,869
JBrowse link
G DAPK1 death associated protein kinase 1 involved_in ISO (PMID:7828849) UniProt PMID:7828849 NCBI chr 9:58,628,872...58,836,205
Ensembl chr 9:86,681,953...86,887,958
JBrowse link
G DAPK3 death associated protein kinase 3 ISO (MGI:1196722|PMID:9488481)
(MGI:3687891|PMID:12917339)
MGI PMID:9488481 PMID:12917339 MGI:1196722 MGI:3687891 NCBI chr19:2,984,806...2,996,782
Ensembl chr19:3,934,496...3,946,011
JBrowse link
G DAXX death domain associated protein ISO (MGI:3687891|PMID:12917339) MGI PMID:12917339 MGI:3687891 NCBI chr 6:32,890,846...32,895,307
Ensembl chr 6:34,004,543...34,008,717
JBrowse link
G DIDO1 death inducer-obliterator 1 ISO (MGI:1340704|PMID:10393935) MGI PMID:10393935 MGI:1340704 NCBI chr20:59,264,759...59,325,092
Ensembl chr20:60,556,923...60,617,265
JBrowse link
G FADD Fas associated via death domain involved_in ISO (PMID:11101870) BHF-UCL PMID:11101870 NCBI chr11:65,300,889...65,305,020 JBrowse link
G FAS Fas cell surface death receptor ISO (MGI:65483|PMID:7511063), (MGI:80946|PMID:8666928) RGD
MGI
PMID:7511063 PMID:8666928 PMID:16953119 MGI:65483 MGI:80946 RGD:1600313 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G FASLG Fas ligand involved_in ISO (MGI:3525895|PMID:15629131), (MGI:65483|PMID:7511063)
(PMID:11101870)
MGI
BHF-UCL
PMID:7511063 PMID:11101870 PMID:15629131 MGI:3525895 MGI:65483 NCBI chr 1:148,159,826...148,167,785
Ensembl chr 1:151,868,430...151,876,281
JBrowse link
G HIP1 huntingtin interacting protein 1 involved_in ISO (PMID:11007801) UniProt PMID:11007801 NCBI chr 7:68,281,899...68,464,233 JBrowse link
G ITGAM integrin subunit alpha M ISO (MGI:3812233|PMID:18685038) ARUK-UCL PMID:18685038 MGI:3812233 NCBI chr16:23,634,476...23,707,147
Ensembl chr16:31,630,146...31,702,406
JBrowse link
G MOAP1 modulator of apoptosis 1 involved_in ISO (PMID:11060313) BHF-UCL PMID:11060313 NCBI chr14:73,814,859...73,817,607
Ensembl chr14:93,152,551...93,153,606
JBrowse link
G NDUFA13 NADH:ubiquinone oxidoreductase subunit A13 involved_in ISO (PMID:10924506) UniProt PMID:10924506 NCBI chr19:18,954,214...18,966,634 JBrowse link
G P2RX4 purinergic receptor P2X 4 involved_in ISO (PMID:17264311) BHF-UCL PMID:17264311 NCBI chr12:118,807,961...118,832,267
Ensembl chr12:122,178,672...122,202,959
JBrowse link
G P2RX7 purinergic receptor P2X 7 ISO PMID:12857854 BHF-UCL PMID:12857854 RGD:8554350 NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068
JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO (MGI:3687891|PMID:12917339) MGI PMID:12917339 MGI:3687891 NCBI chr12:77,114,282...77,224,116
Ensembl chr12:79,969,517...80,070,796
JBrowse link
G PIDD1 p53-induced death domain protein 1 ISO (MGI:3603971|PMID:16183742) MGI PMID:16183742 MGI:3603971 NCBI chr11:816,629...827,295
Ensembl chr11:860,899...867,436
JBrowse link
G PPARD peroxisome proliferator activated receptor delta involved_in ISO (PMID:11551955) UniProt PMID:11551955 NCBI chr 6:34,903,798...34,987,208
Ensembl chr 6:36,003,988...36,081,132
JBrowse link
G PTGIS prostaglandin I2 synthase involved_in ISO (PMID:11551955) UniProt PMID:11551955 NCBI chr20:45,841,238...45,905,641
Ensembl chr20:46,905,665...46,971,612
JBrowse link
G SENP1 SUMO specific peptidase 1 involved_in ISO (PMID:1087798) UniProt PMID:1087798 NCBI chr12:40,624,200...40,689,837
Ensembl chr12:41,507,348...41,558,969
JBrowse link
G SGPL1 sphingosine-1-phosphate lyase 1 involved_in ISO (PMID:14570870) UniProt PMID:14570870 NCBI chr10:67,286,349...67,351,574
Ensembl chr10:69,812,092...69,876,438
JBrowse link
G SHH sonic hedgehog signaling molecule ISO (MGI:5559673|PMID:11044396) Roslin_Institute PMID:11044396 MGI:5559673 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651
JBrowse link
G SPN sialophorin ISO (MGI:1340173|PMID:10429671) MGI PMID:10429671 MGI:1340173 Ensembl chr16:30,035,243...30,036,445 JBrowse link
G TFPT TCF3 fusion partner involved_in ISO (PMID:17041757) UniProt PMID:17041757 NCBI chr19:51,039,142...51,048,346
Ensembl chr19:59,879,141...59,891,335
JBrowse link
G TICAM1 toll like receptor adaptor molecule 1 ISO (MGI:2670551|PMID:12872135) MGI PMID:12872135 MGI:2670551 NCBI chr19:3,836,100...3,852,017
Ensembl chr19:4,787,557...4,790,206
JBrowse link
G TM2D1 TM2 domain containing 1 ISO (MGI:2135414|PMID:11278849) MGI PMID:11278849 MGI:2135414 NCBI chr 1:60,931,583...60,976,340
Ensembl chr 1:62,749,990...62,793,981
JBrowse link
G TNF tumor necrosis factor ISO (MGI:3525895|PMID:15629131), (MGI:67096|PMID:8208546) MGI PMID:8208546 PMID:15629131 MGI:3525895 MGI:67096 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP ISO (MGI:3812233|PMID:18685038) ARUK-UCL PMID:18685038 MGI:3812233 NCBI chr19:32,821,279...32,825,488
Ensembl chr19:41,570,683...41,575,226
JBrowse link
G UMOD uromodulin ISO (MGI:6107740|PMID:28990932) MGI PMID:28990932 MGI:6107740 NCBI chr16:17,960,456...17,980,338
Ensembl chr16:20,430,085...20,449,121
JBrowse link
G VDR vitamin D receptor ISO RGD PMID:9579411 RGD:70308 NCBI chr12:40,828,413...40,891,700
Ensembl chr12:41,702,742...41,766,192
JBrowse link
autophagic cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP2 acid phosphatase 2, lysosomal ISO RGD PMID:18690537 RGD:4892631 NCBI chr11:47,185,611...47,195,174
Ensembl chr11:47,738,845...47,748,450
JBrowse link
G BNIP3 BCL2 interacting protein 3 ISO RGD PMID:19539716 RGD:5128797 NCBI chr10:128,671,663...128,685,952
Ensembl chr10:132,858,211...132,871,634
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B involved_in ISO (PMID:12698196) BHF-UCL PMID:12698196 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541
JBrowse link
G CDKN2D cyclin dependent kinase inhibitor 2D involved_in ISO (PMID:16322758) BHF-UCL PMID:16322758 NCBI chr19:10,118,302...10,120,957 JBrowse link
G CTSL cathepsin L ISO RGD PMID:16176344 RGD:2315590 NCBI chr 9:58,851,899...58,857,170
Ensembl chr 9:86,903,006...86,908,303
JBrowse link
G LAMP1 lysosomal associated membrane protein 1 ISO RGD PMID:18690537 RGD:4892631 NCBI chr13:94,442,507...94,464,061
Ensembl chr13:113,507,401...113,530,457
JBrowse link
G SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 involved_in ISO (MGI:3770552|PMID:17891140)
(PMID:17891140)
UniProt PMID:17891140 MGI:3770552 NCBI chr 1:119,224,304...119,267,986
Ensembl chr 1:88,077,420...88,121,056
JBrowse link
G TP53INP1 tumor protein p53 inducible nuclear protein 1 involved_in ISO (PMID:22421968) UniProt PMID:22421968 NCBI chr 8:91,545,655...91,569,535
Ensembl chr 8:93,747,162...93,767,196
JBrowse link
B cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAK1 BCL2 antagonist/killer 1 ISO (MGI:3588597|PMID:16055554) MGI PMID:16055554 MGI:3588597 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211
JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in ISO (MGI:3588597|PMID:16055554)
(PMID:15214043), (PMID:16424160)
MGI
HGNC-UCL
PMID:15214043 PMID:16055554 PMID:16424160 MGI:3588597 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BCL10 BCL10 immune signaling adaptor NOT ISO (MGI:1355482|PMID:10753917)
(MGI:1930354|PMID:11163238)
MGI PMID:10753917 PMID:11163238 MGI:1355482 MGI:1930354 NCBI chr 1:117,823,388...117,834,314 JBrowse link
G BCL2L11 BCL2 like 11 ISO (MGI:3588597|PMID:16055554) MGI PMID:16055554 MGI:3588597 NCBI chr2A:90,862,070...90,909,833
Ensembl chr2A:112,337,927...112,385,079
JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein ISO (MGI:6150543|PMID:29581031) MGI PMID:29581031 MGI:6150543 NCBI chr22:3,141,147...3,177,448
Ensembl chr22:19,632,359...19,668,858
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO (MGI:3692035|PMID:12970677) MGI PMID:12970677 MGI:3692035 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G PKN1 protein kinase N1 ISO (MGI:5467878|PMID:23223530) MGI PMID:23223530 MGI:5467878 NCBI chr19:13,996,454...14,035,272
Ensembl chr19:14,846,463...14,879,205
JBrowse link
G TNFRSF21 TNF receptor superfamily member 21 ISO (MGI:3628730|PMID:12515813) UniProt PMID:12515813 MGI:3628730 NCBI chr 6:46,815,762...46,894,286
Ensembl chr 6:48,079,749...48,158,356
JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 ISO (MGI:3510272|PMID:15485634) MGI PMID:15485634 MGI:3510272 NCBI chr 6:109,367,333...109,414,601
Ensembl chr 6:113,444,005...113,485,533
JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator involved_in ISO (PMID:15214043) BHF-UCL PMID:15214043 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
canonical Wnt signaling pathway involved in negative regulation of apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway ISO (MGI:3710040|PMID:17377531) MGI PMID:17377531 MGI:3710040 NCBI chr 5:108,070,697...108,208,273
Ensembl chr 5:113,904,352...114,009,709
JBrowse link
G MITF melanocyte inducing transcription factor ISO (MGI:2386811|PMID:12235125) MGI PMID:12235125 MGI:2386811 NCBI chr 3:69,674,064...69,902,078
Ensembl chr 3:71,037,665...71,265,445
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO (MGI:3710040|PMID:17377531) MGI PMID:17377531 MGI:3710040 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G TCF7 transcription factor 7 ISO (MGI:2386811|PMID:12235125) MGI PMID:12235125 MGI:2386811 NCBI chr 5:129,518,134...129,549,972
Ensembl chr 5:135,671,095...135,702,734
JBrowse link
canonical Wnt signaling pathway involved in positive regulation of apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway ISO (MGI:3710040|PMID:17377531) MGI PMID:17377531 MGI:3710040 NCBI chr 5:108,070,697...108,208,273
Ensembl chr 5:113,904,352...114,009,709
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO (MGI:3710040|PMID:17377531) MGI PMID:17377531 MGI:3710040 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
cardiac muscle cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APAF1 apoptotic peptidase activating factor 1 ISO RGD PMID:18197610 RGD:2325741 NCBI chr12:96,224,515...96,311,246
Ensembl chr12:99,637,622...99,726,939
JBrowse link
G BNIP3 BCL2 interacting protein 3 ISO RGD PMID:12226479 RGD:632019 NCBI chr10:128,671,663...128,685,952
Ensembl chr10:132,858,211...132,871,634
JBrowse link
G GNB1 G protein subunit beta 1 involved_in ISO PMID:19723622 MGI PMID:19723622 RGD:8554041 NCBI chr 1:490,415...596,826
Ensembl chr 1:1,647,340...1,701,614
JBrowse link
G GNGT1 G protein subunit gamma transducin 1 ISO PMID:19723622 MGI PMID:19723622 RGD:8554041 NCBI chr 7:85,839,639...85,859,844
Ensembl chr 7:99,446,623...99,451,185
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:21620734 RGD:5686387 NCBI chr14:82,700,881...82,707,020
Ensembl chr14:102,519,699...102,576,723
JBrowse link
G NOL3 nucleolar protein 3 ISO (MGI:3710289|PMID:16505176) UniProt PMID:16505176 MGI:3710289 NCBI chr16:47,516,156...47,521,441 JBrowse link
G RPS6KA2 ribosomal protein S6 kinase A2 ISO (MGI:3710915|PMID:16585392) MGI PMID:16585392 MGI:3710915 NCBI chr 6:164,373,829...164,829,195
Ensembl chr 6:169,355,136...169,806,337
JBrowse link
cell death in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF112 ring finger protein 112 ISO (MGI:6154438|PMID:26792191) UniProt PMID:26792191 MGI:6154438 NCBI chr17:31,688,381...31,701,675
Ensembl chr17:36,860,202...36,894,877
JBrowse link
G SIGMAR1 sigma non-opioid intracellular receptor 1 ISO (MGI:6154438|PMID:26792191) UniProt PMID:26792191 MGI:6154438 NCBI chr 9:34,471,362...34,474,459 JBrowse link
cell death in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF112 ring finger protein 112 ISO (MGI:6154496|PMID:27918959) UniProt PMID:27918959 MGI:6154496 NCBI chr17:31,688,381...31,701,675
Ensembl chr17:36,860,202...36,894,877
JBrowse link
cellular component disassembly involved in execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BOK BCL2 family apoptosis regulator BOK ISO (MGI:5705719|PMID:23429263) UniProt PMID:23429263 MGI:5705719 NCBI chr2B:128,832,458...128,847,918
Ensembl chr2B:247,626,494...247,640,238
JBrowse link
cholangiocyte apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KRT18 keratin 18 ISO RGD PMID:30563999 RGD:27226806 NCBI chr12:35,807,660...35,811,691
Ensembl chr12:36,587,149...36,591,196
JBrowse link
cornification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CERS3 ceramide synthase 3 ISO (MGI:5303015|PMID:22038835) UniProt PMID:22038835 MGI:5303015 NCBI chr15:79,128,338...79,272,018
Ensembl chr15:98,422,256...98,521,775
JBrowse link
G CYP26B1 cytochrome P450 family 26 subfamily B member 1 ISO (MGI:5466369|PMID:22366455) MGI PMID:22366455 MGI:5466369 NCBI chr2A:72,172,658...72,191,410
Ensembl chr2A:73,670,830...73,686,433
JBrowse link
G TMEM79 transmembrane protein 79 ISO (MGI:5519142|PMID:24084074) MGI PMID:24084074 MGI:5519142 NCBI chr 1:131,625,864...131,635,370
Ensembl chr 1:135,455,766...135,465,426
JBrowse link
cytotoxic T cell pyroptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSDMB gasdermin B involved_in ISO (PMID:32299851) UniProt PMID:32299851 NCBI chr17:17,370,351...17,384,639
Ensembl chr17:17,590,018...17,604,177
JBrowse link
G GZMA granzyme A involved_in ISO (PMID:32299851) UniProt PMID:32299851 NCBI chr 5:58,919,129...58,926,620
Ensembl chr 5:60,540,988...60,548,506
JBrowse link
death-inducing signaling complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase ISO (MGI:3612236|PMID:16365167) MGI PMID:16365167 MGI:3612236 NCBI chr 3:12,510,084...12,590,598
Ensembl chr 3:12,853,415...12,932,871
JBrowse link
ectopic germ cell programmed cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator ISO (MGI:2680318|PMID:14660547)
(MGI:3691300|PMID:17107997)
MGI PMID:14660547 PMID:17107997 MGI:2680318 MGI:3691300 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G CASP2 caspase 2 ISO (MGI:3691999|PMID:11536012) MGI PMID:11536012 MGI:3691999 NCBI chr 7:135,283,072...135,307,855
Ensembl chr 7:147,773,749...147,792,958
JBrowse link
G IL1A interleukin 1 alpha ISO (MGI:3691999|PMID:11536012) MGI PMID:11536012 MGI:3691999 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801
JBrowse link
G IL1B interleukin 1 beta ISO (MGI:3691999|PMID:11536012) MGI PMID:11536012 MGI:3691999 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO (MGI:2680318|PMID:14660547) MGI PMID:14660547 MGI:2680318 NCBI chr 4:69,199,543...69,282,323
Ensembl chr 4:75,761,946...75,844,473
JBrowse link
G KITLG KIT ligand ISO (MGI:3691300|PMID:17107997) MGI PMID:17107997 MGI:3691300 NCBI chr12:86,036,501...86,124,274
Ensembl chr12:89,341,921...89,436,758
JBrowse link
G LOC100991353 caspase-4 ISO (MGI:3691999|PMID:11536012) MGI PMID:11536012 MGI:3691999 NCBI chr11:99,883,353...99,909,185
Ensembl chr11:103,366,138...103,391,824
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit ISO (MGI:3700621|PMID:17145779) MGI PMID:17145779 MGI:3700621 NCBI chr 8:44,201,391...44,386,803
Ensembl chr 8:41,593,029...41,778,299
JBrowse link
endothelial cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:25187962) UniProt PMID:25187962 NCBI chr2B:89,631,622...89,823,438
Ensembl chr2B:207,780,741...207,961,072
JBrowse link
G COL4A3 collagen type IV alpha 3 chain involved_in ISO (PMID:10766752) UniProt PMID:10766752 NCBI chr2B:114,410,703...114,559,336
Ensembl chr2B:233,294,783...233,371,021
JBrowse link
G FGF21 fibroblast growth factor 21 ISO RGD PMID:22166524 RGD:10401877 NCBI chr19:45,755,466...45,758,472 JBrowse link
G HIPK1 homeodomain interacting protein kinase 1 involved_in ISO (PMID:15701637) UniProt PMID:15701637 NCBI chr 1:88,579,603...88,627,988
Ensembl chr 1:123,633,134...123,677,714
JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 ISO RGD PMID:17932313 RGD:10412644 NCBI chr 6:134,316,841...134,582,843
Ensembl chr 6:138,406,398...138,641,727
JBrowse link
G TNF tumor necrosis factor ISO (MGI:5796069|PMID:26808574) BHF-UCL PMID:26808574 MGI:5796069 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
epithelial cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EXOC5 exocyst complex component 5 ISO (MGI:5699235|PMID:26040895) MGI PMID:26040895 MGI:5699235 NCBI chr14:37,775,555...37,839,751
Ensembl chr14:56,050,175...56,089,615
JBrowse link
epithelial cell apoptotic process involved in palatal shelf morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G JAG2 jagged canonical Notch ligand 2 ISO (MGI:3624929|PMID:16607638) MGI PMID:16607638 MGI:3624929 NCBI chr14:85,785,586...85,812,056
Ensembl chr14:105,569,837...105,585,878
JBrowse link
execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIFM3 apoptosis inducing factor mitochondria associated 3 involved_in ISO (PMID:15764604) BHF-UCL PMID:15764604 NCBI chr22:3,189,169...3,205,394
Ensembl chr22:19,679,873...19,695,349
JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO (MGI:2387238|PMID:12124386) MGI PMID:12124386 MGI:2387238 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756
JBrowse link
G BBC3 BCL2 binding component 3 involved_in ISO (PMID:11463391), (PMID:11463392) UniProt PMID:11463391 PMID:11463392 NCBI chr19:44,203,517...44,215,860 JBrowse link
G CASP3 caspase 3 involved_in ISO (MGI:2150278|PMID:11549719)
(PMID:11350920)
(PMID:8689682)
(MGI:2387238|PMID:12124386), (MGI:2674166|PMID:12954857), (MGI:3056854|PMID:15456877)
(MGI:3615714|PMID:16469926)
MGI
BHF-UCL
UniProt
PMID:8689682 PMID:11350920 PMID:11549719 PMID:12124386 PMID:12954857 PMID:15456877 PMID:16469926 MGI:2150278 MGI:2387238 MGI:2674166 MGI:3056854 MGI:3615714 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185
JBrowse link
G CASP7 caspase 7 ISO (MGI:3615714|PMID:16469926) MGI PMID:16469926 MGI:3615714 NCBI chr10:110,273,318...110,324,800
Ensembl chr10:113,707,780...113,758,626
JBrowse link
G CASP8 caspase 8 involved_in ISO (MGI:5602910|PMID:24813850), (MGI:5602911|PMID:24813849)
(PMID:21737330)
UniProt PMID:21737330 PMID:24813849 PMID:24813850 MGI:5602910 MGI:5602911 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468
JBrowse link
G CIDEC cell death inducing DFFA like effector c involved_in ISO (PMID:12429024) UniProt PMID:12429024 NCBI chr 3:9,811,995...9,836,069
Ensembl chr 3:10,048,554...10,173,107
JBrowse link
G LOC100991444 cat eye syndrome critical region protein 2 involved_in ISO (PMID:12762840) BHF-UCL PMID:12762840 NCBI chr22:795,525...987,645
Ensembl chr22:16,335,754...16,412,640
JBrowse link
G MADD MAP kinase activating death domain involved_in ISO (MGI:3700423|PMID:14735464)
(PMID:14735464)
UniProt PMID:14735464 MGI:3700423 NCBI chr11:47,216,006...47,276,422
Ensembl chr11:47,773,733...47,828,360
JBrowse link
G STK24 serine/threonine kinase 24 involved_in ISO (PMID:12107159) UniProt PMID:12107159 NCBI chr13:79,614,662...79,744,772
Ensembl chr13:98,764,900...98,837,807
JBrowse link
G TAOK1 TAO kinase 1 involved_in ISO (PMID:16407310) UniProt PMID:16407310 NCBI chr17:27,222,725...27,385,713
Ensembl chr17:27,746,797...27,840,623
JBrowse link
execution phase of necroptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MLKL mixed lineage kinase domain like pseudokinase ISO (MGI:6434626|PMID:32296175), (MGI:6436412|PMID:32200799)
(MGI:6436434|PMID:27321907)
UniProt PMID:27321907 PMID:32200799 PMID:32296175 MGI:6434626 MGI:6436412 MGI:6436434 NCBI chr16:55,237,656...55,266,945
Ensembl chr16:74,591,635...74,620,667
JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 ISO (MGI:6436445|PMID:27746097), (MGI:6442612|PMID:27917412) UniProt PMID:27746097 PMID:27917412 MGI:6436445 MGI:6442612 NCBI chr14:5,112,512...5,116,486
Ensembl chr14:23,235,796...23,239,821
JBrowse link
extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1B activin A receptor type 1B involved_in ISO (PMID:9884026) BHF-UCL PMID:9884026 NCBI chr12:36,765,655...36,811,355
Ensembl chr12:37,541,867...37,566,660
JBrowse link
G BAD BCL2 associated agonist of cell death involved_in ISO (PMID:18852119) UniProt PMID:18852119 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257
JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in ISO (PMID:15214043) BHF-UCL PMID:15214043 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BID BH3 interacting domain death agonist ISO (MGI:1343652|PMID:10476969) MGI PMID:10476969 MGI:1343652 NCBI chr22:1,164,787...1,205,051
Ensembl chr22:16,594,186...16,632,844
JBrowse link
G CASP8 caspase 8 involved_in ISO (MGI:5521568|PMID:22089168)
(PMID:21785459)
(MGI:2386520|PMID:12065591), (MGI:3687663|PMID:10588860)
(MGI:5486419|PMID:22675671)
(MGI:6401035|PMID:31748744)
MGI
UniProt
PMID:10588860 PMID:12065591 PMID:21785459 PMID:22089168 PMID:22675671 PMID:31748744 MGI:2386520 MGI:3687663 MGI:5486419 MGI:5521568 MGI:6401035 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468
JBrowse link
G CD27 CD27 molecule involved_in ISO (PMID:9177220) BHF-UCL PMID:9177220 NCBI chr12:6,575,104...6,582,127
Ensembl chr12:6,492,119...6,499,427
JBrowse link
G CD70 CD70 molecule involved_in ISO (PMID:9177220) BHF-UCL PMID:9177220 NCBI chr19:5,615,056...5,621,055 JBrowse link
G FADD Fas associated via death domain involved_in ISO (MGI:3687663|PMID:10588860)
(PMID:21785459)
(PMID:16611992)
(MGI:3603971|PMID:16183742)
MGI
UniProt
PMID:10588860 PMID:16183742 PMID:16611992 PMID:21785459 MGI:3603971 MGI:3687663 NCBI chr11:65,300,889...65,305,020 JBrowse link
G FAS Fas cell surface death receptor involved_in ISO (MGI:3818355|PMID:17980593)
(PMID:22891283)
(MGI:2183141|PMID:12011074)
MGI
UniProt
PMID:12011074 PMID:17980593 PMID:22891283 MGI:2183141 MGI:3818355 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G FASLG Fas ligand involved_in ISO (PMID:22891283) UniProt PMID:22891283 NCBI chr 1:148,159,826...148,167,785
Ensembl chr 1:151,868,430...151,876,281
JBrowse link
G G0S2 G0/G1 switch 2 involved_in ISO (PMID:19706769) UniProt PMID:19706769 NCBI chr 1:185,251,903...185,252,882
Ensembl chr 1:190,057,382...190,057,693
JBrowse link
G GSK3A glycogen synthase kinase 3 alpha ISO (MGI:4818524|PMID:20371704) ARUK-UCL PMID:20371704 MGI:4818524 NCBI chr19:39,118,330...39,130,768
Ensembl chr19:47,710,197...47,726,948
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO (MGI:4818524|PMID:20371704) ARUK-UCL PMID:20371704 MGI:4818524 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
G HIPK1 homeodomain interacting protein kinase 1 involved_in ISO (PMID:15701637) UniProt PMID:15701637 NCBI chr 1:88,579,603...88,627,988
Ensembl chr 1:123,633,134...123,677,714
JBrowse link
G IFI27 interferon alpha inducible protein 27 involved_in ISO (PMID:24970806) UniProt PMID:24970806 NCBI chr14:74,742,775...74,748,820
Ensembl chr14:94,046,694...94,082,022
JBrowse link
G IFNG interferon gamma involved_in ISO (PMID:16942485) BHF-UCL PMID:16942485 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G IL12A interleukin 12A involved_in ISO (PMID:16942485) BHF-UCL PMID:16942485 NCBI chr 3:157,011,675...157,019,897
Ensembl chr 3:165,061,505...165,068,666
JBrowse link
G IL33 interleukin 33 ISO (MGI:5437589|PMID:22660580) MGI PMID:22660580 MGI:5437589 NCBI chr 9:6,027,014...6,069,540
Ensembl chr 9:6,234,178...6,248,624
JBrowse link
G INHBA inhibin subunit beta A involved_in ISO (PMID:9884026) BHF-UCL PMID:9884026 NCBI chr 7:42,538,591...42,556,578
Ensembl chr 7:42,580,730...42,595,097
JBrowse link
G JAK2 Janus kinase 2 ISO (MGI:5009182|PMID:12426001) MGI PMID:12426001 MGI:5009182 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626
JBrowse link
G KRT18 keratin 18 ISO (MGI:3711847|PMID:10747083) MGI PMID:10747083 MGI:3711847 NCBI chr12:35,807,660...35,811,691
Ensembl chr12:36,587,149...36,591,196
JBrowse link
G KRT8 keratin 8 ISO (MGI:3711847|PMID:10747083) MGI PMID:10747083 MGI:3711847 NCBI chr12:35,855,367...35,863,248
Ensembl chr12:36,634,582...36,642,564
JBrowse link
G LOC100978213 TNF superfamily member 12 ISO (MGI:2667292|PMID:12821115) MGI PMID:12821115 MGI:2667292 NCBI chr17:7,581,163...7,589,809
Ensembl chr17:7,567,766...7,575,575
JBrowse link
G MLLT11 MLLT11 transcription factor 7 cofactor involved_in ISO (PMID:18852119) UniProt PMID:18852119 NCBI chr 1:126,408,533...126,417,624 JBrowse link
G NDUFA13 NADH:ubiquinone oxidoreductase subunit A13 ISO (MGI:1930995|PMID:10924506) MGI PMID:10924506 MGI:1930995 NCBI chr19:18,954,214...18,966,634 JBrowse link
G P2RX7 purinergic receptor P2X 7 ISO PMID:12857854
(MGI:3700102|PMID:17286969)
PMID:8614837
BHF-UCL
MGI
PMID:8614837 PMID:12857854 PMID:17286969 MGI:3700102 RGD:69918 RGD:8554350 NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068
JBrowse link
G PARP2 poly(ADP-ribose) polymerase 2 ISO (MGI:2386520|PMID:12065591) MGI PMID:12065591 MGI:2386520 NCBI chr14:1,215,727...1,230,006
Ensembl chr14:19,269,046...19,282,853
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (PMID:16207722) UniProt PMID:16207722 NCBI chr16:1,394,447...1,463,735 JBrowse link
G PIDD1 p53-induced death domain protein 1 ISO (MGI:3603971|PMID:16183742) MGI PMID:16183742 MGI:3603971 NCBI chr11:816,629...827,295
Ensembl chr11:860,899...867,436
JBrowse link
G PML PML nuclear body scaffold ISO (MGI:1306978|PMID:9806545) MGI PMID:9806545 MGI:1306978 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883
JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in ISO (PMID:10521396), (PMID:8612133)
(PMID:7538908)
BHF-UCL PMID:7538908 PMID:8612133 PMID:10521396 NCBI chr 6:2,893,802...2,943,162
Ensembl chr 6:2,997,343...3,045,078
JBrowse link
G RNF41 ring finger protein 41 involved_in ISO (PMID:14765125) UniProt PMID:14765125 NCBI chr12:32,693,349...32,710,866
Ensembl chr12:32,944,814...32,962,584
JBrowse link
G SGPP1 sphingosine-1-phosphate phosphatase 1 ISO (MGI:2386810|PMID:12235122) MGI PMID:12235122 MGI:2386810 NCBI chr14:44,265,017...44,308,897 JBrowse link
G SIVA1 SIVA1 apoptosis inducing factor involved_in ISO (PMID:9177220) BHF-UCL PMID:9177220 NCBI chr14:85,404,148...85,408,254
Ensembl chr14:105,196,118...105,202,678
JBrowse link
G SMAD3 SMAD family member 3 involved_in ISO (PMID:15334054) BHF-UCL PMID:15334054 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185
JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in ISO (PMID:15334054) BHF-UCL PMID:15334054 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISO (PMID:17217916) BHF-UCL PMID:17217916 NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041
JBrowse link
G TLR3 toll like receptor 3 involved_in ISO (PMID:21737330) UniProt PMID:21737330 NCBI chr 4:178,238,352...178,256,264
Ensembl chr 4:190,446,487...190,462,728
JBrowse link
G TNF tumor necrosis factor involved_in ISO (MGI:5510543|PMID:19498109)
(PMID:11577081), (PMID:16611992)
(MGI:5521568|PMID:22089168)
MGI
UniProt
PMID:11577081 PMID:16611992 PMID:19498109 PMID:22089168 MGI:5510543 MGI:5521568 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a involved_in ISO (PMID:21785459) UniProt PMID:21785459 NCBI chr 8:22,440,502...22,476,790
Ensembl chr 8:19,378,547...19,414,724
JBrowse link
G TNFRSF12A TNF receptor superfamily member 12A ISO (MGI:2667292|PMID:12821115) MGI PMID:12821115 MGI:2667292 NCBI chr16:1,962,179...1,964,223
Ensembl chr16:3,134,577...3,136,581
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO (MGI:69721|PMID:7990930) MGI PMID:7990930 MGI:69721 NCBI chr 1:10,915,743...10,957,765
Ensembl chr 1:12,130,663...12,172,646
JBrowse link
G TRADD TNFRSF1A associated via death domain involved_in ISO (MGI:5521568|PMID:22089168)
(PMID:16611992)
MGI
UniProt
PMID:16611992 PMID:22089168 MGI:5521568 NCBI chr16:47,499,881...47,506,220
Ensembl chr16:66,889,006...66,891,016
JBrowse link
G WWOX WW domain containing oxidoreductase ISO (MGI:3851310|PMID:19366691) MGI PMID:19366691 MGI:3851310 NCBI chr16:58,689,609...59,800,333
Ensembl chr16:78,125,302...79,231,546
JBrowse link
G ZNF274 zinc finger protein 274 ISO (MGI:1929440|PMID:10545116) MGI PMID:10545116 MGI:1929440 NCBI chr19:55,163,153...55,221,933
Ensembl chr19:64,017,183...64,048,097
JBrowse link
extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAD BCL2 associated agonist of cell death ISO (MGI:3032484|PMID:14967141)
(MGI:3029504|PMID:12431371)
(MGI:2183839|PMID:12115603), (MGI:2675215|PMID:12944463)
MGI PMID:12115603 PMID:12431371 PMID:12944463 PMID:14967141 MGI:2183839 MGI:2675215 MGI:3029504 MGI:3032484 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257
JBrowse link
G BAG3 BAG cochaperone 3 ISO (MGI:3513163|PMID:11527400) MGI PMID:11527400 MGI:3513163 NCBI chr10:116,221,747...116,248,692
Ensembl chr10:119,643,963...119,665,964
JBrowse link
G BAK1 BCL2 antagonist/killer 1 ISO (MGI:3581932|PMID:15967824)
(MGI:3575206|PMID:15680329)
MGI PMID:15680329 PMID:15967824 MGI:3575206 MGI:3581932 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211
JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO (MGI:3581932|PMID:15967824)
(MGI:3575206|PMID:15680329)
MGI PMID:15680329 PMID:15967824 MGI:3575206 MGI:3581932 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO (MGI:2179928|PMID:12082633) MGI PMID:12082633 MGI:2179928 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BCL2L1 BCL2 like 1 ISO (MGI:2183839|PMID:12115603) MGI PMID:12115603 MGI:2183839 NCBI chr20:27,955,688...28,015,950
Ensembl chr20:29,088,055...29,146,585
JBrowse link
G BCL2L11 BCL2 like 11 ISO (MGI:3581932|PMID:15967824) MGI PMID:15967824 MGI:3581932 NCBI chr2A:90,862,070...90,909,833
Ensembl chr2A:112,337,927...112,385,079
JBrowse link
G CASP2 caspase 2 ISO (MGI:3691999|PMID:11536012) MGI PMID:11536012 MGI:3691999 NCBI chr 7:135,283,072...135,307,855
Ensembl chr 7:147,773,749...147,792,958
JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 involved_in ISO (PMID:17701904) BHF-UCL PMID:17701904 NCBI chr12:32,811,533...32,834,958
Ensembl chr12:33,063,434...33,084,994
JBrowse link
G EYA2 EYA transcriptional coactivator and phosphatase 2 ISO (MGI:2158099|PMID:11700312) MGI PMID:11700312 MGI:2158099 NCBI chr20:43,226,621...43,520,301
Ensembl chr20:44,310,451...44,607,468
JBrowse link
G FADD Fas associated via death domain ISO (MGI:2675560|PMID:13679421) MGI PMID:13679421 MGI:2675560 NCBI chr11:65,300,889...65,305,020 JBrowse link
G FAS Fas cell surface death receptor ISO (MGI:2675560|PMID:13679421) MGI PMID:13679421 MGI:2675560 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G FOXO3 forkhead box O3 ISO (MGI:3029504|PMID:12431371) MGI PMID:12431371 MGI:3029504 NCBI chr 6:106,360,519...106,485,676
Ensembl chr 6:110,406,266...110,516,272
JBrowse link
G GSK3A glycogen synthase kinase 3 alpha ISO (MGI:5514334|PMID:16543145) UniProt PMID:16543145 MGI:5514334 NCBI chr19:39,118,330...39,130,768
Ensembl chr19:47,710,197...47,726,948
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO (MGI:5514334|PMID:16543145) UniProt PMID:16543145 MGI:5514334 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
G IGF1 insulin like growth factor 1 ISO (MGI:3029504|PMID:12431371) MGI PMID:12431371 MGI:3029504 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177
JBrowse link
G IL1A interleukin 1 alpha ISO (MGI:3691999|PMID:11536012) MGI PMID:11536012 MGI:3691999 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801
JBrowse link
G IL1B interleukin 1 beta ISO (MGI:3691999|PMID:11536012) MGI PMID:11536012 MGI:3691999 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G IL2 interleukin 2 ISO (MGI:2179928|PMID:12082633) MGI PMID:12082633 MGI:2179928 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G IL3 interleukin 3 ISO (MGI:2387238|PMID:12124386), (MGI:2675215|PMID:12944463), (MGI:3032484|PMID:14967141), (MGI:3057092|PMID:15231831), (MGI:3513163|PMID:11527400), (MGI:3575206|PMID:15680329) MGI PMID:11527400 PMID:12124386 PMID:12944463 PMID:14967141 PMID:15231831 PMID:15680329 MGI:2387238 MGI:2675215 MGI:3032484 MGI:3057092 MGI:3513163 MGI:3575206 NCBI chr 5:127,483,843...127,486,388
Ensembl chr 5:133,647,667...133,650,213
JBrowse link
G IL4 interleukin 4 ISO (MGI:2183839|PMID:12115603) MGI PMID:12115603 MGI:2183839 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G ITGAV integrin subunit alpha V ISO (MGI:3530680|PMID:15591537) BHF-UCL PMID:15591537 MGI:3530680 NCBI chr2B:73,880,962...73,972,486
Ensembl chr2B:191,680,655...191,773,028
JBrowse link
G ITM2B integral membrane protein 2B ISO (MGI:2179928|PMID:12082633) MGI PMID:12082633 MGI:2179928 NCBI chr13:29,383,318...29,412,018 JBrowse link
G KITLG KIT ligand ISO (MGI:3038547|PMID:15039234) MGI PMID:15039234 MGI:3038547 NCBI chr12:86,036,501...86,124,274
Ensembl chr12:89,341,921...89,436,758
JBrowse link
G LCN2 lipocalin 2 ISO (MGI:4821076|PMID:16377569) MGI PMID:16377569 MGI:4821076 NCBI chr 9:99,259,278...99,274,494
Ensembl chr 9:127,940,799...127,944,798
JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO (MGI:5514334|PMID:16543145)
(PMID:16543145)
UniProt PMID:16543145 MGI:5514334 NCBI chr 1:125,918,760...125,923,952
Ensembl chr 1:129,566,827...129,572,086
JBrowse link
G MKNK1 MAPK interacting serine/threonine kinase 1 ISO (MGI:3793518|PMID:17903173) MGI PMID:17903173 MGI:3793518 NCBI chr 1:45,859,888...45,906,840
Ensembl chr 1:47,215,693...47,262,317
JBrowse link
G MKNK2 MAPK interacting serine/threonine kinase 2 ISO (MGI:3793518|PMID:17903173) MGI PMID:17903173 MGI:3793518 NCBI chr19:1,045,316...1,059,023
Ensembl chr19:2,018,822...2,032,429
JBrowse link
G MOAP1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) BHF-UCL PMID:16199525 NCBI chr14:73,814,859...73,817,607
Ensembl chr14:93,152,551...93,153,606
JBrowse link
G NGF nerve growth factor ISO (MGI:2681362|PMID:14623868) MGI PMID:14623868 MGI:2681362 NCBI chr 1:87,223,597...87,276,759 JBrowse link
extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAD BCL2 associated agonist of cell death ISO (MGI:3029504|PMID:12431371) MGI PMID:12431371 MGI:3029504 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257
JBrowse link
G BAG3 BAG cochaperone 3 involved_in ISO (PMID:10597216) MGI PMID:10597216 NCBI chr10:116,221,747...116,248,692
Ensembl chr10:119,643,963...119,665,964
JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO (MGI:1349210|PMID:10597216) MGI PMID:10597216 MGI:1349210 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in ISO (PMID:10597216) MGI PMID:10597216 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BEX3 brain expressed X-linked 3 ISO (MGI:1859527|PMID:10764727) MGI PMID:10764727 MGI:1859527 NCBI chr  X:92,606,496...92,608,240
Ensembl chr  X:102,985,284...102,986,464
JBrowse link
G BLOC1S2 biogenesis of lysosomal organelles complex 1 subunit 2 involved_in ISO (PMID:18188704) UniProt PMID:18188704 NCBI chr10:96,878,280...96,887,830
Ensembl chr10:100,358,095...100,368,640
JBrowse link
G CASP8 caspase 8 ISO (MGI:3054336|PMID:15322156) MGI PMID:15322156 MGI:3054336 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468
JBrowse link
G CASP8AP2 caspase 8 associated protein 2 involved_in ISO (MGI:1347587|PMID:10235259)
(PMID:17245429)
MGI
UniProt
PMID:10235259 PMID:17245429 MGI:1347587 NCBI chr 6:87,707,152...87,754,836
Ensembl chr 6:90,996,127...91,023,757
JBrowse link
G DAB2IP DAB2 interacting protein involved_in ISO (PMID:19903888) BHF-UCL PMID:19903888 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336
JBrowse link
G DAPK1 death associated protein kinase 1 ISO (MGI:3051747|PMID:15010850)
(MGI:4431305|PMID:20053891)
MGI PMID:15010850 PMID:20053891 MGI:3051747 MGI:4431305 NCBI chr 9:58,628,872...58,836,205
Ensembl chr 9:86,681,953...86,887,958
JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in ISO (PMID:18846110) UniProt PMID:18846110 NCBI chr  X:33,780,381...33,796,829
Ensembl chr  X:41,475,116...41,505,837
JBrowse link
G DDX47 DEAD-box helicase 47 involved_in ISO (PMID:15977068) UniProt PMID:15977068 NCBI chr12:12,838,201...12,854,874
Ensembl chr12:13,216,152...13,232,846
JBrowse link
G DEDD death effector domain containing ISO (MGI:1306907|PMID:9774341) MGI PMID:9774341 MGI:1306907 NCBI chr 1:136,533,756...136,545,107
Ensembl chr 1:140,447,011...140,457,876
JBrowse link
G DEDD2 death effector domain containing 2 involved_in ISO (PMID:11741985) UniProt PMID:11741985 NCBI chr19:39,086,735...39,108,312
Ensembl chr19:47,678,915...47,700,431
JBrowse link
G DELE1 DAP3 binding cell death enhancer 1 involved_in ISO (PMID:20563667) UniProt PMID:20563667 NCBI chr 5:137,283,938...137,302,203
Ensembl chr 5:143,394,554...143,412,532
JBrowse link
G FAS Fas cell surface death receptor ISO (MGI:2687085|PMID:12801066), (MGI:3029504|PMID:12431371), (MGI:77677|PMID:8524870)
(MGI:1340173|PMID:10429671)
(MGI:3029504|PMID:12431371)
(MGI:2687085|PMID:12801066), (MGI:3038547|PMID:15039234), (MGI:3576402|PMID:15632112), (MGI:3687663|PMID:10588860), (MGI:3819026|PMID:18363966), (MGI:5009197|PMID:10950869), (MGI:77677|PMID:8524870)
MGI PMID:8524870 PMID:10429671 PMID:10588860 PMID:10950869 PMID:12431371 PMID:12801066 PMID:15039234 PMID:15632112 PMID:18363966 MGI:1340173 MGI:2687085 MGI:3029504 MGI:3038547 MGI:3576402 MGI:3687663 MGI:3819026 MGI:5009197 MGI:77677 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G FASLG Fas ligand involved_in ISO (PMID:18835034), (PMID:26582200)
(MGI:3038547|PMID:15039234), (MGI:3687663|PMID:10588860)
RGD
BHF-UCL
MGI
PMID:10588860 PMID:15039234 PMID:16689665 PMID:18835034 PMID:26582200 MGI:3038547 MGI:3687663 RGD:1582444 NCBI chr 1:148,159,826...148,167,785
Ensembl chr 1:151,868,430...151,876,281
JBrowse link
G GABARAP GABA type A receptor-associated protein involved_in ISO (PMID:15977068) UniProt PMID:15977068 NCBI chr17:7,270,316...7,272,365
Ensembl chr17:7,257,659...7,260,276
JBrowse link
G IL18 interleukin 18 involved_in ISO (PMID:11429161)
(PMID:11131641)
UniProt PMID:11131641 PMID:11429161 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371
JBrowse link
G MOAP1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) BHF-UCL PMID:16199525 NCBI chr14:73,814,859...73,817,607
Ensembl chr14:93,152,551...93,153,606
JBrowse link
G NF1 neurofibromin 1 ISO (MGI:3038547|PMID:15039234) MGI PMID:15039234 MGI:3038547 NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295
JBrowse link
G NGF nerve growth factor involved_in ISO (PMID:14985763) BHF-UCL PMID:14985763 NCBI chr 1:87,223,597...87,276,759 JBrowse link
G PIDD1 p53-induced death domain protein 1 ISO (MGI:3603971|PMID:16183742) MGI PMID:16183742 MGI:3603971 NCBI chr11:816,629...827,295
Ensembl chr11:860,899...867,436
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO (MGI:3038547|PMID:15039234) MGI PMID:15039234 MGI:3038547 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960
JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 ISO (MGI:3612236|PMID:16365167) MGI PMID:16365167 MGI:3612236 NCBI chr2A:11,167,353...11,331,339
Ensembl chr2A:11,318,370...11,478,986
JBrowse link
G SORT1 sortilin 1 involved_in ISO (PMID:14985763) BHF-UCL PMID:14985763 NCBI chr 1:111,687,119...111,775,339 JBrowse link
G TNF tumor necrosis factor involved_in ISO (MGI:4420852|PMID:20080598)
(PMID:10521396), (PMID:18202225), (PMID:18676776)
(MGI:3029504|PMID:12431371)
MGI
BHF-UCL
PMID:10521396 PMID:12431371 PMID:18202225 PMID:18676776 PMID:20080598 MGI:3029504 MGI:4420852 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a ISO RGD PMID:19934367 RGD:4142856 NCBI chr 8:22,440,502...22,476,790
Ensembl chr 8:19,378,547...19,414,724
JBrowse link
fibroblast apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAK1 BCL2 antagonist/killer 1 ISO (MGI:3689797|PMID:15901672) MGI PMID:15901672 MGI:3689797 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211
JBrowse link
G BCL10 BCL10 immune signaling adaptor NOT ISO (MGI:1930354|PMID:11163238) MGI PMID:11163238 MGI:1930354 NCBI chr 1:117,823,388...117,834,314 JBrowse link
G CUL3 cullin 3 ISO (MGI:3713609|PMID:17339333) MGI PMID:17339333 MGI:3713609 NCBI chr2B:111,714,533...111,827,080
Ensembl chr2B:230,289,195...230,378,991
JBrowse link
fibroblast growth factor receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGFR3 fibroblast growth factor receptor 3 involved_in ISO (PMID:17561467) UniProt PMID:17561467 NCBI chr 4:1,933,172...1,948,742 JBrowse link
fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGFR2 fibroblast growth factor receptor 2 ISO (MGI:4887304|PMID:20345253) UniProt PMID:20345253 MGI:4887304 NCBI chr10:118,055,854...118,175,440
Ensembl chr10:121,469,735...121,588,815
JBrowse link
glial cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator ISO microglia RGD PMID:18931364 RGD:2313998 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO microglia RGD PMID:18931364 RGD:2313998 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BID BH3 interacting domain death agonist ISO microglia RGD PMID:18931364 RGD:2313998 NCBI chr22:1,164,787...1,205,051
Ensembl chr22:16,594,186...16,632,844
JBrowse link
G CASP3 caspase 3 ISO microglia
(MGI:2150278|PMID:11549719)
RGD
MGI
PMID:11549719 PMID:18931364 MGI:2150278 RGD:2313998 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185
JBrowse link
G CASP9 caspase 9 ISO microglia RGD PMID:18931364 RGD:2313998 NCBI chr 1:14,630,659...14,662,865
Ensembl chr 1:15,624,666...15,656,266
JBrowse link
G LOC100986481 cytochrome c ISO microglia RGD PMID:18931364 RGD:2313998 NCBI chr 7:25,784,900...25,791,598
Ensembl chr 7:25,396,013...25,398,549
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO RGD PMID:14997384 RGD:10412686 NCBI chr10:45,806,748...45,936,362 JBrowse link
G RB1 RB transcriptional corepressor 1 ISO (MGI:2150278|PMID:11549719) MGI PMID:11549719 MGI:2150278 NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575
JBrowse link
glomerular visceral epithelial cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO RGD PMID:23515840 RGD:8693403 NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941
JBrowse link
granzyme-mediated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UBE4B ubiquitination factor E4B involved_in ISO (PMID:11802788) UniProt PMID:11802788 NCBI chr 1:8,801,707...8,949,465
Ensembl chr 1:10,033,084...10,178,759
JBrowse link
granzyme-mediated programmed cell death signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BNIP3 BCL2 interacting protein 3 involved_in ISO (PMID:9396766) GO_Central PMID:9396766 NCBI chr10:128,671,663...128,685,952
Ensembl chr10:132,858,211...132,871,634
JBrowse link
G GSDMB gasdermin B involved_in ISO (PMID:32299851) UniProt PMID:32299851 NCBI chr17:17,370,351...17,384,639
Ensembl chr17:17,590,018...17,604,177
JBrowse link
G GSDME gasdermin E involved_in ISO (PMID:31953257), (PMID:32188940) UniProt PMID:31953257 PMID:32188940 NCBI chr 7:25,373,485...25,433,001
Ensembl chr 7:24,977,838...25,039,525
JBrowse link
G GZMA granzyme A involved_in ISO (PMID:32299851) UniProt PMID:32299851 NCBI chr 5:58,919,129...58,926,620
Ensembl chr 5:60,540,988...60,548,506
JBrowse link
G GZMB granzyme B involved_in ISO (MGI:3665503|PMID:16618603)
(PMID:31953257), (PMID:32188940)
(MGI:3531039|PMID:15454490)
MGI
UniProt
PMID:15454490 PMID:16618603 PMID:31953257 PMID:32188940 MGI:3531039 MGI:3665503 NCBI chr14:5,399,888...5,403,200
Ensembl chr14:23,523,619...23,526,931
JBrowse link
G LAMP1 lysosomal associated membrane protein 1 involved_in ISO (PMID:23632890) GO_Central PMID:23632890 NCBI chr13:94,442,507...94,464,061
Ensembl chr13:113,507,401...113,530,457
JBrowse link
G SRGN serglycin involved_in ISO (PMID:11911826) GO_Central PMID:11911826 NCBI chr10:65,554,873...65,572,108
Ensembl chr10:68,089,392...68,106,250
JBrowse link
hepatocyte apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARF6 ADP ribosylation factor 6 ISO (MGI:3653957|PMID:16880525) MGI PMID:16880525 MGI:3653957 NCBI chr14:30,482,191...30,486,741
Ensembl chr14:48,789,329...48,789,856
JBrowse link
G BCL2L1 BCL2 like 1 ISO (MGI:1351384|PMID:10618441) MGI PMID:10618441 MGI:1351384 NCBI chr20:27,955,688...28,015,950
Ensembl chr20:29,088,055...29,146,585
JBrowse link
G BID BH3 interacting domain death agonist ISO (MGI:5566519|PMID:20436477) MGI PMID:20436477 MGI:5566519 NCBI chr22:1,164,787...1,205,051
Ensembl chr22:16,594,186...16,632,844
JBrowse link
G CASP8 caspase 8 ISO (MGI:3054336|PMID:15322156) MGI PMID:15322156 MGI:3054336 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha ISO RGD PMID:19833194 RGD:9588622 NCBI chr2A:25,229,593...25,344,733
Ensembl chr2A:25,331,095...25,412,605
JBrowse link
G FAS Fas cell surface death receptor ISO (MGI:5566519|PMID:20436477) MGI PMID:20436477 MGI:5566519 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:28638224 RGD:13792732 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
G GSN gelsolin involved_in ISO (PMID:22952982) UniProt PMID:22952982 NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831
JBrowse link
G KRT18 keratin 18 ISO (MGI:3711847|PMID:10747083) MGI PMID:10747083 MGI:3711847 NCBI chr12:35,807,660...35,811,691
Ensembl chr12:36,587,149...36,591,196
JBrowse link
G KRT8 keratin 8 ISO (MGI:3711847|PMID:10747083) MGI PMID:10747083 MGI:3711847 NCBI chr12:35,855,367...35,863,248
Ensembl chr12:36,634,582...36,642,564
JBrowse link
G MTCH2 mitochondrial carrier 2 ISO (MGI:5566519|PMID:20436477) MGI PMID:20436477 MGI:5566519 NCBI chr11:47,566,884...47,596,711
Ensembl chr11:48,115,774...48,146,312
JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:20675006 RGD:6482714 NCBI chr 7:98,841,974...98,885,446
Ensembl chr 7:111,570,148...111,611,614
JBrowse link
G RB1 RB transcriptional corepressor 1 ISO (MGI:2150278|PMID:11549719) MGI PMID:11549719 MGI:2150278 NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575
JBrowse link
G STK3 serine/threonine kinase 3 ISO (MGI:4420852|PMID:20080598) MGI PMID:20080598 MGI:4420852 NCBI chr 8:95,098,185...95,465,324
Ensembl chr 8:97,355,173...97,708,437
JBrowse link
G STK4 serine/threonine kinase 4 ISO (MGI:4420852|PMID:20080598) MGI PMID:20080598 MGI:4420852 NCBI chr20:41,297,157...41,410,487
Ensembl chr20:42,389,615...42,503,014
JBrowse link
hippocampal neuron apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK2B calcium/calmodulin dependent protein kinase II beta ISO RGD PMID:25126162 RGD:13681928 NCBI chr 7:44,930,859...45,040,078
Ensembl chr 7:45,001,267...45,110,342
JBrowse link
hormone-mediated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRH corticotropin releasing hormone ISO RGD PMID:11790788 RGD:1358682 NCBI chr 8:62,714,721...62,716,979
Ensembl chr 8:64,383,419...64,384,009
JBrowse link
G ESR2 estrogen receptor 2 ISO (MGI:3047056|PMID:15187231) MGI PMID:15187231 MGI:3047056 NCBI chr14:44,807,875...44,919,780
Ensembl chr14:63,064,402...63,131,303
JBrowse link
G METTL21C methyltransferase like 21C ISO (MGI:5781029|PMID:24677265) MGI PMID:24677265 MGI:5781029 NCBI chr13:83,845,572...83,855,215
Ensembl chr13:102,981,536...102,990,336
JBrowse link
induction by virus of host autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 ISO (MGI:5544501|PMID:24310610) UniProt PMID:24310610 MGI:5544501 NCBI chr15:18,871,867...18,973,380
Ensembl chr15:37,120,044...37,229,211
JBrowse link
G PHB2 prohibitin 2 involved_in ISO (PMID:32276428) UniProt PMID:32276428 NCBI chr12:7,097,073...7,102,474
Ensembl chr12:7,013,195...7,018,053
JBrowse link
induction of programmed cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAPTM5 lysosomal protein transmembrane 5 involved_in ISO (PMID:19787053) ARUK-UCL PMID:19787053 NCBI chr 1:30,005,941...30,031,366
Ensembl chr 1:31,032,963...31,058,385
JBrowse link
inflammatory cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAS Fas cell surface death receptor ISO (MGI:2687085|PMID:12801066) MGI PMID:12801066 MGI:2687085 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G FASLG Fas ligand ISO RGD PMID:16154149 RGD:1582433 NCBI chr 1:148,159,826...148,167,785
Ensembl chr 1:151,868,430...151,876,281
JBrowse link
G IFNG interferon gamma ISO (MGI:3027059|PMID:11457893) MGI PMID:11457893 MGI:3027059 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 ISO (MGI:2178865|PMID:11923874) MGI PMID:11923874 MGI:2178865 NCBI chr 1:39,545,264...39,589,721
Ensembl chr 1:40,869,076...40,912,747
JBrowse link
inhibition of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2L12 BCL2 like 12 involved_in ISO (PMID:22262180) UniProt PMID:22262180 NCBI chr19:46,679,749...46,688,539 JBrowse link
G FCMR Fc fragment of IgM receptor ISO (MGI:3576402|PMID:15632112) MGI PMID:15632112 MGI:3576402 NCBI chr 1:182,506,551...182,525,249
Ensembl chr 1:186,786,147...186,803,789
JBrowse link
G NOL3 nucleolar protein 3 involved_in ISO (PMID:15509781) UniProt PMID:15509781 NCBI chr16:47,516,156...47,521,441 JBrowse link
G XIAP X-linked inhibitor of apoptosis ISO (MGI:2681362|PMID:14623868) MGI PMID:14623868 MGI:2681362 NCBI chr  X:113,052,164...113,105,160
Ensembl chr  X:123,232,643...123,278,606
JBrowse link
intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAD BCL2 associated agonist of cell death involved_in ISO (PMID:18676776) UniProt PMID:18676776 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257
JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in ISO (PMID:16462759), (PMID:9219694) BHF-UCL PMID:9219694 PMID:16462759 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BNIP3 BCL2 interacting protein 3 ISO (MGI:3696331|PMID:16954213) MGI PMID:16954213 MGI:3696331 NCBI chr10:128,671,663...128,685,952
Ensembl chr10:132,858,211...132,871,634
JBrowse link
G CLU clusterin involved_in ISO (PMID:21567405) UniProt PMID:21567405 NCBI chr 8:26,867,973...26,884,838
Ensembl chr 8:24,070,053...24,083,523
JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in ISO (PMID:16301996) UniProt PMID:16301996 NCBI chr  X:33,780,381...33,796,829
Ensembl chr  X:41,475,116...41,505,837
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO (MGI:3696331|PMID:16954213) MGI PMID:16954213 MGI:3696331 NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078
JBrowse link
G HTRA2 HtrA serine peptidase 2 ISO (MGI:3511636|PMID:15509788) MGI PMID:15509788 MGI:3511636 NCBI chr2A:74,596,020...74,599,790
Ensembl chr2A:76,102,240...76,106,152
JBrowse link
G IFI6 interferon alpha inducible protein 6 involved_in ISO (PMID:26244642) UniProt PMID:26244642 NCBI chr 1:26,929,129...26,935,205
Ensembl chr 1:27,972,866...27,978,890
JBrowse link
G LGALS12 galectin 12 involved_in ISO (PMID:11435439) MGI PMID:11435439 NCBI chr11:58,859,004...58,869,957
Ensembl chr11:62,210,487...62,221,110
JBrowse link
G LOC100991353 caspase-4 involved_in ISO (PMID:15123740) ParkinsonsUK-UCL PMID:15123740 NCBI chr11:99,883,353...99,909,185
Ensembl chr11:103,366,138...103,391,824
JBrowse link
G LOC100994669 cytochrome c oxidase assembly factor 8 ISO (MGI:3694393|PMID:16782708) MGI PMID:16782708 MGI:3694393 NCBI chr14:84,189,323...84,217,230
Ensembl chr14:104,000,692...104,027,230
JBrowse link
G MLLT11 MLLT11 transcription factor 7 cofactor involved_in ISO (PMID:18852119) UniProt PMID:18852119 NCBI chr 1:126,408,533...126,417,624 JBrowse link
G MSH6 mutS homolog 6 ISO (MGI:2677657|PMID:14632208) MGI PMID:14632208 MGI:2677657 NCBI chr2A:47,901,591...47,926,662
Ensembl chr2A:48,824,350...48,849,779
JBrowse link
G NBN nibrin ISO (MGI:3805397|PMID:18614044) MGI PMID:18614044 MGI:3805397 NCBI chr 8:86,622,797...86,674,202
Ensembl chr 8:88,575,198...88,626,307
JBrowse link
G NOL3 nucleolar protein 3 ISO (MGI:5573029|PMID:24312627) UniProt PMID:24312627 MGI:5573029 NCBI chr16:47,516,156...47,521,441 JBrowse link
G PLSCR1 phospholipid scramblase 1 ISO (MGI:5315351|PMID:15863367) UniProt PMID:15863367 MGI:5315351 NCBI chr 3:143,528,967...143,558,468
Ensembl chr 3:151,112,483...151,132,964
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:14500711) UniProt PMID:14500711 NCBI chr18:53,286,590...53,290,913
Ensembl chr18:56,611,098...56,615,449
JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F involved_in ISO (PMID:11559703) UniProt PMID:11559703 NCBI chr22:4,039,032...4,072,165
Ensembl chr22:20,520,022...20,553,128
JBrowse link
G PRKCA protein kinase C alpha ISO (MGI:2671671|PMID:12928424) MGI PMID:12928424 MGI:2671671 NCBI chr17:60,246,485...60,747,158
Ensembl chr17:65,454,907...65,947,903
JBrowse link
G SGPP1 sphingosine-1-phosphate phosphatase 1 ISO (MGI:1932564|PMID:10859351) MGI PMID:10859351 MGI:1932564 NCBI chr14:44,265,017...44,308,897 JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:23313858) AgBase PMID:23313858 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069
JBrowse link
G SIVA1 SIVA1 apoptosis inducing factor NOT|involved_in ISO (PMID:12011449) BHF-UCL PMID:12011449 NCBI chr14:85,404,148...85,408,254
Ensembl chr14:105,196,118...105,202,678
JBrowse link
intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator ISO (MGI:1344924|PMID:10479688) MGI PMID:10479688 MGI:1344924 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BOK BCL2 family apoptosis regulator BOK involved_in ISO (PMID:15102863) UniProt PMID:15102863 NCBI chr2B:128,832,458...128,847,918
Ensembl chr2B:247,626,494...247,640,238
JBrowse link
G DDX5 DEAD-box helicase 5 involved_in ISO (PMID:15660129) UniProt PMID:15660129 NCBI chr17:58,594,956...58,603,570
Ensembl chr17:63,689,082...63,696,142
JBrowse link
G E2F1 E2F transcription factor 1 ISO (MGI:1927703|PMID:11095619) MGI PMID:11095619 MGI:1927703 NCBI chr20:29,963,083...29,973,860
Ensembl chr20:31,103,764...31,110,604
JBrowse link
G E2F2 E2F transcription factor 2 ISO (MGI:1927703|PMID:11095619) MGI PMID:11095619 MGI:1927703 NCBI chr 1:22,696,695...22,722,840
Ensembl chr 1:23,683,293...23,707,951
JBrowse link
G EDA2R ectodysplasin A2 receptor ISO (MGI:4454200|PMID:20434500) MGI PMID:20434500 MGI:4454200 NCBI chr  X:55,786,361...55,830,798
Ensembl chr  X:65,850,306...65,894,975
JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase involved_in ISO (PMID:15313915) UniProt PMID:15313915 NCBI chr 3:59,670,777...61,177,974 JBrowse link
G HINT1 histidine triad nucleotide binding protein 1 involved_in ISO (PMID:16835243) UniProt PMID:16835243 NCBI chr 5:126,587,934...126,594,032
Ensembl chr 5:132,755,766...132,761,823
JBrowse link
G IFI16 interferon gamma inducible protein 16 involved_in ISO (PMID:21573174) UniProt PMID:21573174 NCBI chr 1:134,364,706...134,405,910
Ensembl chr 1:138,152,328...138,203,424
JBrowse link
G JMY junction mediating and regulatory protein, p53 cofactor ISO (MGI:1891484|PMID:10518217) MGI PMID:10518217 MGI:1891484 NCBI chr 5:35,981,666...36,076,428
Ensembl chr 5:36,261,971...36,567,349
JBrowse link
G MYBBP1A MYB binding protein 1a involved_in ISO (PMID:21471221) UniProt PMID:21471221 NCBI chr17:4,593,741...4,610,203
Ensembl chr17:4,586,431...4,603,097
JBrowse link
G PDK2 pyruvate dehydrogenase kinase 2 involved_in ISO (PMID:22123926) UniProt PMID:22123926 NCBI chr17:44,185,463...44,202,221
Ensembl chr17:49,060,030...49,076,115
JBrowse link
G PERP p53 apoptosis effector related to PMP22 ISO (MGI:1929912|PMID:10733530) MGI PMID:10733530 MGI:1929912 NCBI chr 6:135,845,845...135,863,603
Ensembl chr 6:139,931,031...139,947,792
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (MGI:2679929|PMID:14500851)
(PMID:15102863)
UniProt PMID:14500851 PMID:15102863 MGI:2679929 NCBI chr18:53,286,590...53,290,913
Ensembl chr18:56,611,098...56,615,449
JBrowse link
G PML PML nuclear body scaffold ISO (MGI:3034149|PMID:14992722) MGI PMID:14992722 MGI:3034149 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883
JBrowse link
G POU4F1 POU class 4 homeobox 1 ISO (MGI:5825431|PMID:17145718) UniProt PMID:17145718 MGI:5825431 NCBI chr13:59,821,614...59,829,671 JBrowse link
G POU4F2 POU class 4 homeobox 2 ISO (MGI:5825431|PMID:17145718) UniProt PMID:17145718 MGI:5825431 NCBI chr 4:138,969,157...138,972,730
Ensembl chr 4:150,626,392...150,629,961
JBrowse link
G PPP1R13B protein phosphatase 1 regulatory subunit 13B involved_in ISO (PMID:11684014) UniProt PMID:11684014 NCBI chr14:84,359,917...84,474,892
Ensembl chr14:104,168,873...104,232,974
JBrowse link
G PYCARD PYD and CARD domain containing involved_in ISO (PMID:14730312) UniProt PMID:14730312 NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828
JBrowse link
G RRP8 ribosomal RNA processing 8 involved_in ISO (PMID:21471221) UniProt PMID:21471221 NCBI chr11:6,630,695...6,735,711
Ensembl chr11:6,415,003...6,418,414
JBrowse link
G SHISA5 shisa family member 5 ISO (MGI:2183272|PMID:12135983) MGI PMID:12135983 MGI:2183272 NCBI chr 3:48,389,924...48,426,064
Ensembl chr 3:49,471,604...49,508,840
JBrowse link
G STK11 serine/threonine kinase 11 involved_in ISO (PMID:11430832) UniProt PMID:11430832 Ensembl chr19:1,188,537...1,210,677 JBrowse link
G TP53 tumor protein p53 involved_in ISO (MGI:4454200|PMID:20434500)
(PMID:12172011), (PMID:16322561), (PMID:17310983)
(MGI:2183272|PMID:12135983), (MGI:3589512|PMID:16107883), (MGI:5883206|PMID:22262176)
MGI
BHF-UCL
CAFA
PMID:12135983 PMID:12172011 PMID:16107883 PMID:16322561 PMID:17310983 PMID:20434500 PMID:22262176 MGI:2183272 MGI:3589512 MGI:4454200 MGI:5883206 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G TP53BP2 tumor protein p53 binding protein 2 involved_in ISO (PMID:11684014) UniProt PMID:11684014 NCBI chr 1:199,403,194...199,469,079
Ensembl chr 1:204,414,218...204,457,739
JBrowse link
G WWOX WW domain containing oxidoreductase ISO (MGI:1930321|PMID:11058590) MGI PMID:11058590 MGI:1930321 NCBI chr16:58,689,609...59,800,333
Ensembl chr16:78,125,302...79,231,546
JBrowse link
G ZNF385B zinc finger protein 385B involved_in ISO (PMID:22945289) UniProt PMID:22945289 NCBI chr2B:66,696,635...67,115,011
Ensembl chr2B:184,400,205...184,726,522
JBrowse link
intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAD5 ATPase family AAA domain containing 5 ISO (MGI:3584078|PMID:15983387) MGI PMID:15983387 MGI:3584078 NCBI chr17:25,944,259...26,009,317
Ensembl chr17:25,436,195...25,496,242
JBrowse link
G ATM ATM serine/threonine kinase ISO (MGI:1926715|PMID:11040211), (MGI:3652689|PMID:16777961)
(MGI:3714678|PMID:17476307)
MGI PMID:11040211 PMID:16777961 PMID:17476307 MGI:1926715 MGI:3652689 MGI:3714678 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
G BAD BCL2 associated agonist of cell death ISO (MGI:3057092|PMID:15231831)
(MGI:3029504|PMID:12431371)
MGI PMID:12431371 PMID:15231831 MGI:3029504 MGI:3057092 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257
JBrowse link
G BAK1 BCL2 antagonist/killer 1 ISO (MGI:3689797|PMID:15901672)
(MGI:3581932|PMID:15967824)
MGI PMID:15901672 PMID:15967824 MGI:3581932 MGI:3689797 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211
JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO (MGI:3689797|PMID:15901672)
(MGI:3581932|PMID:15967824)
(MGI:2675761|PMID:12952892)
MGI PMID:12952892 PMID:15901672 PMID:15967824 MGI:2675761 MGI:3581932 MGI:3689797 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO (MGI:3584078|PMID:15983387) MGI PMID:15983387 MGI:3584078 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BCL2L1 BCL2 like 1 ISO (MGI:2677658|PMID:14517295) MGI PMID:14517295 MGI:2677658 NCBI chr20:27,955,688...28,015,950
Ensembl chr20:29,088,055...29,146,585
JBrowse link
G BCL2L11 BCL2 like 11 involved_in ISO (MGI:3581932|PMID:15967824)
(PMID:11546872)
MGI PMID:11546872 PMID:15967824 MGI:3581932 NCBI chr2A:90,862,070...90,909,833
Ensembl chr2A:112,337,927...112,385,079
JBrowse link
G BRCA1 BRCA1 DNA repair associated involved_in ISO (PMID:14654789) MGI PMID:14654789 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815
JBrowse link
G BRCA2 BRCA2 DNA repair associated ISO (MGI:3714678|PMID:17476307) MGI PMID:17476307 MGI:3714678 NCBI chr13:13,574,422...13,658,967
Ensembl chr13:32,010,066...32,091,332
JBrowse link
G CASP9 caspase 9 involved_in ISO (PMID:15657060) UniProt PMID:15657060 NCBI chr 1:14,630,659...14,662,865
Ensembl chr 1:15,624,666...15,656,266
JBrowse link
G CHEK2 checkpoint kinase 2 involved_in ISO (PMID:12717439), (PMID:18644861)
(PMID:12402044)
UniProt PMID:12402044 PMID:12717439 PMID:18644861 NCBI chr22:9,757,038...9,811,171 JBrowse link
G E2F1 E2F transcription factor 1 involved_in ISO (PMID:12717439) UniProt PMID:12717439 NCBI chr20:29,963,083...29,973,860
Ensembl chr20:31,103,764...31,110,604
JBrowse link
G EI24 EI24 autophagy associated transmembrane protein ISO (MGI:1350723|PMID:10594026) MGI PMID:10594026 MGI:1350723 NCBI chr11:120,389,136...120,404,347
Ensembl chr11:124,302,289...124,317,346
JBrowse link
G EPHA2 EPH receptor A2 involved_in ISO (PMID:18339848) UniProt PMID:18339848 NCBI chr 1:15,259,915...15,292,983
Ensembl chr 1:16,253,513...16,284,787
JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor ISO (MGI:1913261|PMID:11005836) MGI PMID:11005836 MGI:1913261 NCBI chr10:44,703,720...44,784,948 JBrowse link
G FNIP2 folliculin interacting protein 2 ISO (MGI:5284752|PMID:19137017) UniProt PMID:19137017 MGI:5284752 NCBI chr 4:151,086,854...151,224,192
Ensembl chr 4:162,896,805...163,032,167
JBrowse link
G HIC1 HIC ZBTB transcriptional repressor 1 involved_in ISO (MGI:5297787|PMID:16269335)
(PMID:16269335)
UniProt PMID:16269335 MGI:5297787 NCBI chr17:2,045,960...2,051,483 JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:11854317 RGD:625692 NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063
JBrowse link
G HTRA2 HtrA serine peptidase 2 involved_in ISO (PMID:11602612) ParkinsonsUK-UCL PMID:11602612 NCBI chr2A:74,596,020...74,599,790
Ensembl chr2A:76,102,240...76,106,152
JBrowse link
G IER3 immediate early response 3 ISO (MGI:3775338|PMID:11753682) MGI PMID:11753682 MGI:3775338 NCBI chr 6:30,488,162...30,489,784 JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in ISO (PMID:20188669) UniProt PMID:20188669 NCBI chr 1:182,070,565...182,096,797
Ensembl chr 1:186,351,807...186,377,971
JBrowse link
G MAEL maelstrom spermatogenic transposon silencer ISO (MGI:3813746|PMID:18694567) MGI PMID:18694567 MGI:3813746 NCBI chr 1:142,341,646...142,442,521
Ensembl chr 1:146,195,482...146,228,669
JBrowse link
G MBD4 methyl-CpG binding domain 4, DNA glycosylase ISO (MGI:2678630|PMID:14562041) MGI PMID:14562041 MGI:2678630 NCBI chr 3:126,489,125...126,498,034
Ensembl chr 3:133,839,643...133,851,450
JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member ISO (MGI:3689797|PMID:15901672) MGI PMID:15901672 MGI:3689797 NCBI chr 1:125,918,760...125,923,952
Ensembl chr 1:129,566,827...129,572,086
JBrowse link
G MLH1 mutL homolog 1 ISO (MGI:2678630|PMID:14562041) MGI PMID:14562041 MGI:2678630 NCBI chr 3:36,899,828...36,957,076
Ensembl chr 3:37,189,439...37,245,801
JBrowse link
G MOAP1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) BHF-UCL PMID:16199525 NCBI chr14:73,814,859...73,817,607
Ensembl chr14:93,152,551...93,153,606
JBrowse link
G MSH2 mutS homolog 2 ISO (MGI:1334080|PMID:10097137)
(MGI:3029112|PMID:14744764)
MGI PMID:10097137 PMID:14744764 MGI:1334080 MGI:3029112 NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461
JBrowse link
G MSH6 mutS homolog 6 ISO (MGI:3053495|PMID:15324697) MGI PMID:15324697 MGI:3053495 NCBI chr2A:47,901,591...47,926,662
Ensembl chr2A:48,824,350...48,849,779
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO (MGI:2677658|PMID:14517295) MGI PMID:14517295 MGI:2677658 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G NFATC4 nuclear factor of activated T cells 4 ISO (MGI:3709926|PMID:17242187) MGI PMID:17242187 MGI:3709926 NCBI chr14:5,141,699...5,156,021
Ensembl chr14:23,266,702...23,279,249
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO (MGI:3709926|PMID:17242187) MGI PMID:17242187 MGI:3709926 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 ISO (MGI:2675761|PMID:12952892) MGI PMID:12952892 MGI:2675761 NCBI chr18:53,286,590...53,290,913
Ensembl chr18:56,611,098...56,615,449
JBrowse link
G PML PML nuclear body scaffold involved_in ISO (MGI:3580934|PMID:15626733)
(PMID:12402044)
(MGI:1306978|PMID:9806545)
MGI
UniProt
PMID:9806545 PMID:12402044 PMID:15626733 MGI:1306978 MGI:3580934 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883
JBrowse link
G POLB DNA polymerase beta ISO (MGI:1334987|PMID:10197627) MGI PMID:10197627 MGI:1334987 NCBI chr 8:41,582,370...41,615,950
Ensembl chr 8:39,026,991...39,060,464
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit ISO (MGI:2450507|PMID:12604618) MGI PMID:12604618 MGI:2450507 NCBI chr 8:44,201,391...44,386,803
Ensembl chr 8:41,593,029...41,778,299
JBrowse link
G SFN stratifin involved_in ISO (PMID:11574543) HGNC-UCL PMID:11574543 NCBI chr 1:26,126,212...26,127,761
Ensembl chr 1:27,182,834...27,183,580
JBrowse link
G SIRT1 sirtuin 1 ISO (MGI:5297787|PMID:16269335) UniProt PMID:16269335 MGI:5297787 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069