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ONTOLOGY REPORT - ANNOTATIONS

Term:spermine metabolic process
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Accession:GO:0008215 term browser browse the term
Definition:The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.
Synonyms:exact_synonym: spermine metabolism


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spermine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMS spermine synthase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9467015) Ensembl
MGI		 PMID:9467015 GO_REF:0000107 NCBI chr  X:18,118,332...18,169,396
Ensembl chr  X:18,118,256...18,169,390 		JBrowse link
spermine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SAT2 spermidine/spermine N1-acetyltransferase family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,911,725...52,913,314
Ensembl chr12:52,911,725...52,913,363 		JBrowse link
spermine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMD1 adenosylmethionine decarboxylase 1 involved_in ISO
IEA
IBA		 RGD
InterPro
GO_Central
TreeGrafter		 PMID:1415709 PMID:10430362 PMID:10712236 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 RGD:1578320 RGD:7242911 RGD:7242912 NCBI chr 1:76,839,448...76,863,745
Ensembl chr 1:76,839,731...76,863,738 		JBrowse link
G LOC100516636 S-adenosylmethionine decarboxylase proenzyme-like involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 9:115,525,531...115,535,296 JBrowse link
G SMS spermine synthase involved_in ISO
IBA
IEA		 RGD
GO_Central
TreeGrafter
InterPro		 PMID:8494549 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 RGD:7242928 NCBI chr  X:18,118,332...18,169,396
Ensembl chr  X:18,118,256...18,169,390 		JBrowse link
spermine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAOX polyamine oxidase involved_in ISO
IEA		 RGD
Ensembl		 PMID:7560898 GO_REF:0000107 RGD:7244191 NCBI chr14:141,360,509...141,369,642
Ensembl chr14:141,360,608...141,369,641 		JBrowse link
G SMOX spermine oxidase involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:12141946) RGD
Ensembl
MGI
GO_Central		 PMID:12141946 PMID:15541750 GO_REF:0000033 GO_REF:0000107 RGD:7244190 NCBI chr17:31,552,927...31,592,007
Ensembl chr17:31,548,636...31,591,975 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17799
    metabolic process 10358
      organic substance metabolic process 9930
        organonitrogen compound metabolic process 5025
          amine metabolic process 127
            biogenic amine metabolic process 107
              polyamine metabolic process 21
                spermine metabolic process 6
                  arginine catabolic process to spermine 0
                  spermine acetylation 1
                  spermine biosynthetic process 3
                  spermine catabolic process 2
paths to the root