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ONTOLOGY REPORT - ANNOTATIONS


Term:spermine metabolic process
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Accession:GO:0008215 term browser browse the term
Definition:The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.
Synonyms:exact_synonym: spermine metabolism


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spermine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sms spermine synthase acts_upstream_of_or_within ISO MGI:2180359 (MGI:1197776|PMID:9467015) RGD PMID:9467015 MGI:1197776 NCBI chr  X:37,516,949...37,572,657
Ensembl chr  X:37,516,931...37,570,822
JBrowse link
spermine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat1 spermidine/spermine N1-acetyl transferase 1 IC RGD PMID:15541750 RGD:7244190 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 involved_in ISO (PMID:12803540) RGD PMID:12803540 NCBI chr10:54,340,756...54,343,507
Ensembl chr10:54,340,372...54,343,224
JBrowse link
spermine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
IMP
(MGI:3584197|PMID:11856372)
PMID:21873635
RGD PMID:11856372 PMID:10430362 PMID:21873635 PMID:10712236 PMID:1415709 MGI:3584197, RGD:1578320, RGD:13792537, RGD:7242911, RGD:7242912 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
JBrowse link
G Sms spermine synthase involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:8494549 PMID:21873635 RGD:7242928, RGD:13792537 NCBI chr  X:37,516,949...37,572,657
Ensembl chr  X:37,516,931...37,570,822
JBrowse link
spermine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase involved_in IDA
ISO
(PMID:16354669) RGD PMID:16354669 PMID:7560898 PMID:16354669 RGD:7244191, RGD:12790650 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
G Smox spermine oxidase acts_upstream_of_or_within
involved_in
IDA
ISO
(MGI:2429361|PMID:12141946)
(PMID:18422650)
RGD PMID:12141946 PMID:18422650 PMID:15541750 MGI:2429361, RGD:7244190 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      nitrogen compound metabolic process 9982
        cellular nitrogen compound metabolic process 6561
          cellular amine metabolic process 117
            cellular biogenic amine metabolic process 104
              polyamine metabolic process 19
                spermine metabolic process 6
                  arginine catabolic process to spermine 0
                  spermine acetylation 2
                  spermine biosynthetic process 2
                  spermine catabolic process 2
Path 2
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      organic substance metabolic process 11337
        organonitrogen compound metabolic process 6802
          amine metabolic process 125
            cellular amine metabolic process 117
              cellular biogenic amine metabolic process 104
                polyamine metabolic process 19
                  spermine metabolic process 6
                    arginine catabolic process to spermine 0
                    spermine acetylation 2
                    spermine biosynthetic process 2
                    spermine catabolic process 2
paths to the root