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ONTOLOGY REPORT - ANNOTATIONS


Term:androgen metabolic process
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Accession:GO:0008209 term browser browse the term
Definition:The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
Synonyms:exact_synonym: androgen metabolism


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androgen metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin IDA RGD PMID:18094363 RGD:2325639 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:7508385)
Ensembl
RGD
PMID:7508385, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 4:65,110,706...65,143,930
Ensembl chr 4:65,110,746...65,143,941
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IMP
ISO
MGI:MGI:2154536 (MGI:MGI:2136569|PMID:11356695) RGD PMID:11356695, PMID:19492405 MGI:MGI:2136569, RGD:4890392 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 ISO (PMID:11294878) RGD PMID:11294878 NCBI chr 3:55,623,671...55,645,883
Ensembl chr 3:55,623,634...55,648,325
JBrowse link
G Esr1 estrogen receptor 1 ISO
IEA
MGI:MGI:2150897 (MGI:MGI:3839071|PMID:18755802)
GO_REF:0000107
RGD
Ensembl
PMID:18755802 GO_REF:0000107, MGI:MGI:3839071 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 ISO
ISS
(PMID:12917011)
GO_REF:0000024
RGD
UniProt
PMID:12917011 GO_REF:0000024 NCBI chr  X:21,696,796...21,699,241
Ensembl chr  X:21,696,772...21,699,241
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 ISO
IEA
(PMID:7487879)
GO_REF:0000107
RGD
Ensembl
PMID:7487879 GO_REF:0000107 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 TAS RGD PMID:9188497 RGD:1299376 NCBI chr 7:2,412,370...2,431,249
Ensembl chr 7:2,412,363...2,431,197
Ensembl chr13:2,412,363...2,431,197
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 ISO
IEA
ISS
(PMID:12732193)
GO_REF:0000107
(MGI:MGI:2662631|PMID:12732193)
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12732193 GO_REF:0000024, GO_REF:0000107, MGI:MGI:2662631 NCBI chr13:88,288,116...88,308,019
Ensembl chr13:88,288,046...88,307,988
JBrowse link
G Hsd17b8 hydroxysteroid (17-beta) dehydrogenase 8 ISO (MGI:MGI:3511120|PMID:9712896) RGD PMID:9712896 MGI:MGI:3511120 NCBI chr20:3,817,212...3,819,316
Ensembl chr20:3,817,179...3,819,235
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IEP dihydrotestosterone RGD PMID:8809674 RGD:5686298 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Plekha1 pleckstrin homology domain containing A1 ISO MGI:MGI:3526857 (MGI:MGI:3820330|PMID:19056881) RGD PMID:19056881 MGI:MGI:3820330 NCBI chr 1:201,429,716...201,481,411
Ensembl chr 1:201,429,771...201,480,877
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IEP nandrolone RGD PMID:23338851 RGD:7241839 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 ISO MGI:MGI:3526851 (MGI:MGI:3820330|PMID:19056881) RGD PMID:19056881 MGI:MGI:3820330 NCBI chr20:30,699,936...30,769,178
Ensembl chr20:30,699,872...30,749,940
JBrowse link
G Shh sonic hedgehog signaling molecule ISO
ISS
IEA
MGI:MGI:1857796 (MGI:MGI:3037217|PMID:15013801)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:15013801 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3037217 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IDA RGD PMID:20954080 RGD:4891498 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 IDA
ISO
(PMID:1944596) RGD PMID:1944596, PMID:20954080 RGD:4891498 NCBI chr 6:25,279,635...25,315,501
Ensembl chr 6:25,279,626...25,315,511
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase ISO MGI:MGI:3526866 (MGI:MGI:3820330|PMID:19056881) RGD PMID:19056881 MGI:MGI:3820330 NCBI chr 2:157,316,293...157,342,979
Ensembl chr 2:157,316,266...157,341,469
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 ISO
ISS
(PMID:17442341)
GO_REF:0000024
RGD
UniProt
PMID:17442341 GO_REF:0000024 NCBI chr14:22,597,103...22,619,968 JBrowse link
androgen biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 TAS RGD PMID:7702752 RGD:1298833 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 IDA androstenedione RGD PMID:8612487 RGD:728619 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 IDA
ISO
(PMID:25322271) RGD PMID:25322271, PMID:1985917 RGD:632871 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Med1 mediator complex subunit 1 ISO
ISS
(PMID:19497978)
GO_REF:0000024
RGD
UniProt
PMID:19497978 GO_REF:0000024 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Scarb1 scavenger receptor class B, member 1 IDA RGD PMID:12746305 RGD:1304382 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IDA
ISO
dihydrotestosterone
MGI:MGI:1857454 (MGI:MGI:3045995|PMID:15249131)
RGD PMID:15249131, PMID:12606426 MGI:MGI:3045995, RGD:4891962 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 IDA
ISO
dihydrotestosterone
(MGI:MGI:3045995|PMID:15249131)
RGD PMID:15249131, PMID:12606426 MGI:MGI:3045995, RGD:4891962 NCBI chr 6:25,279,635...25,315,501
Ensembl chr 6:25,279,626...25,315,511
JBrowse link
androgen catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEA
ISO
GO_REF:0000107
(PMID:26482249)
Ensembl
RGD
PMID:26482249 GO_REF:0000107 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 ISO (PMID:12697717) RGD PMID:12697717 NCBI chr14:7,054,724...7,104,567
Ensembl chr14:7,073,445...7,104,566
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO (PMID:26482249) RGD PMID:26482249 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IDA RGD PMID:2339109 RGD:70289 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756
JBrowse link
negative regulation of androgen biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 Wnt family member 4 IEA
ISO
GO_REF:0000107
(PMID:16959810)
Ensembl
RGD
PMID:16959810 GO_REF:0000107 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      hormone metabolic process 215
        cellular hormone metabolic process 128
          androgen metabolic process 27
            androgen biosynthetic process + 8
            androgen catabolic process 4
Path 2
Term Annotations click to browse term
  biological_process 20014
    biological regulation 13759
      regulation of biological quality 4284
        regulation of hormone levels 586
          hormone metabolic process 215
            cellular hormone metabolic process 128
              androgen metabolic process 27
                androgen biosynthetic process + 8
                androgen catabolic process 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.