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ONTOLOGY REPORT - ANNOTATIONS


Term:androgen metabolic process
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Accession:GO:0008209 term browser browse the term
Definition:The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
Synonyms:exact_synonym: androgen metabolism


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androgen metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin IDA RGD PMID:18094363 RGD:2325639 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 involved_in ISO
IBA
IEA
(PMID:7508385)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:7508385 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 acts_upstream_of_or_within IMP
ISO
MGI:2154536 (MGI:2136569|PMID:11356695) RGD PMID:11356695 PMID:19492405 MGI:2136569, RGD:4890392 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 involved_in ISO (PMID:11294878) RGD PMID:11294878 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241
JBrowse link
G Esr1 estrogen receptor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2150897 (MGI:3839071|PMID:18755802)
Ensembl
RGD
PMID:18755802 GO_REF:0000107 MGI:3839071 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 involved_in ISO
IEA
ISS
(PMID:12917011)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12917011 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:21,089,152...21,091,597
Ensembl chr  X:21,089,122...21,109,488
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 involved_in ISO
IEA
(PMID:7487879)
GO_REF:0000107
RGD
Ensembl
PMID:7487879 GO_REF:0000107 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 TAS RGD PMID:9188497 RGD:1299376 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 involved_in ISO
ISS
IEA
(PMID:12732193)
(MGI:2662631|PMID:12732193)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:12732193 GO_REF:0000024 GO_REF:0000107 MGI:2662631 NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017
JBrowse link
G Hsd17b8 hydroxysteroid (17-beta) dehydrogenase 8 acts_upstream_of_or_within ISO (MGI:3511120|PMID:9712896) RGD PMID:9712896 MGI:3511120 NCBI chr20:4,826,725...4,828,742
Ensembl chr20:4,822,026...4,828,742
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IEP dihydrotestosterone RGD PMID:8809674 RGD:5686298 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Plekha1 pleckstrin homology domain containing A1 acts_upstream_of_or_within ISO MGI:3526857 (MGI:3820330|PMID:19056881) RGD PMID:19056881 MGI:3820330 NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IEP nandrolone RGD PMID:23338851 RGD:7241839 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 acts_upstream_of_or_within ISO MGI:3526851 (MGI:3820330|PMID:19056881) RGD PMID:19056881 MGI:3820330 NCBI chr20:29,047,793...29,094,209
Ensembl chr20:29,047,796...29,094,084
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
GO_REF:0000107
MGI:1857796 (MGI:3037217|PMID:15013801)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:15013801 GO_REF:0000024 GO_REF:0000107 MGI:3037217 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IDA RGD PMID:20954080 RGD:4891498 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 involved_in IDA
ISO
(PMID:1944596) RGD PMID:1944596 PMID:20954080 RGD:4891498 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase acts_upstream_of_or_within ISO MGI:3526866 (MGI:3820330|PMID:19056881) RGD PMID:19056881 MGI:3820330 NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 involved_in ISO
ISS
(PMID:17442341)
GO_REF:0000024
RGD
UniProt
PMID:17442341 GO_REF:0000024 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
androgen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 TAS RGD PMID:7702752 RGD:1298833 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 IDA androstenedione RGD PMID:8612487 RGD:728619 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 involved_in IDA
ISO
(PMID:25322271) RGD PMID:25322271 PMID:1985917 RGD:632871 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852
JBrowse link
G Med1 mediator complex subunit 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19497978)
UniProt
RGD
PMID:19497978 GO_REF:0000024 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Scarb1 scavenger receptor class B, member 1 IDA RGD PMID:12746305 RGD:1304382 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 acts_upstream_of_or_within IDA
ISO
dihydrotestosterone
MGI:1857454 (MGI:3045995|PMID:15249131)
RGD PMID:15249131 PMID:12606426 MGI:3045995, RGD:4891962 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 acts_upstream_of_or_within IDA
ISO
dihydrotestosterone
(MGI:3045995|PMID:15249131)
RGD PMID:15249131 PMID:12606426 MGI:3045995, RGD:4891962 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
JBrowse link
androgen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:26482249)
Ensembl
RGD
PMID:26482249 GO_REF:0000107 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 involved_in ISO (PMID:12697717) RGD PMID:12697717 NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161
JBrowse link
G Spp1 secreted phosphoprotein 1 involved_in ISO (PMID:26482249) RGD PMID:26482249 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IDA RGD PMID:2339109 RGD:70289 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
JBrowse link
negative regulation of androgen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 Wnt family member 4 involved_in ISO
IEA
(PMID:16959810)
GO_REF:0000107
RGD
Ensembl
PMID:16959810 GO_REF:0000107 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      hormone metabolic process 235
        cellular hormone metabolic process 145
          androgen metabolic process 27
            androgen biosynthetic process + 8
            androgen catabolic process 4
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological quality 4181
        regulation of hormone levels 611
          hormone metabolic process 235
            cellular hormone metabolic process 145
              androgen metabolic process 27
                androgen biosynthetic process + 8
                androgen catabolic process 4
paths to the root