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ONTOLOGY REPORT - ANNOTATIONS

Term:cholesterol metabolic process
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Accession:GO:0008203 term browser browse the term
Definition:The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.
Synonyms:exact_synonym: cholesterol metabolism
 never_in_taxon: NCBITaxon:4895 ! Schizosaccharomyces;   NCBITaxon:4930 ! Saccharomyces


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cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2153573|PMID:11559713) MGI
Ensembl		 PMID:11559713 GO_REF:0000107 MGI:2153573 NCBI chr 1:246,144,277...246,278,492
Ensembl chr 1:246,144,277...246,278,492 		JBrowse link
G ABCA5 ATP binding cassette subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:11,018,692...11,152,916
Ensembl chr12:11,067,500...11,152,688 		JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:205,561,897...205,628,428
Ensembl chr13:205,561,951...205,628,425 		JBrowse link
G ANGPTL3 angiopoietin like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:149,836,417...149,845,854
Ensembl chr 6:149,832,542...149,845,831 		JBrowse link
G APLP2 amyloid beta precursor like protein 2 acts_upstream_of_or_within ISO (MGI:3762423|PMID:17920016) MGI PMID:17920016 MGI:3762423 NCBI chr 9:56,798,781...56,871,849
Ensembl chr 9:56,798,810...56,872,642 		JBrowse link
G APOA1 apolipoprotein A1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1099137|PMID:9327769), (MGI:1339278|PMID:10357841), (MGI:3487338|PMID:15466405), (MGI:3688492|PMID:9795222), (MGI:3696597|PMID:17071966), (MGI:70854|PMID:7751823)
(MGI:3588626|PMID:15995171)		 MGI
Ensembl
UniProt		 PMID:7751823 PMID:9327769 PMID:9795222 PMID:10357841 PMID:15466405 More... GO_REF:0000043 GO_REF:0000107 MGI:1099137 MGI:1339278 MGI:3487338 MGI:3588626 MGI:3688492 MGI:3696597 MGI:70854 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,392...44,218,713 		JBrowse link
G APOA2 apolipoprotein A2 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (MGI:1339279|PMID:10357838)
(PMID:21873635)
(MGI:1339279|PMID:10357838), (MGI:2180727|PMID:8647961)		 MGI
GO_Central
Ensembl		 PMID:8647961 PMID:10357838 PMID:21873635 GO_REF:0000107 MGI:1339279 MGI:2180727 NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,319 		JBrowse link
G APOA4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:44,201,587...44,204,072
Ensembl chr 9:44,201,508...44,204,206 		JBrowse link
G APOB apolipoprotein B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:117,250,096...117,316,200
Ensembl chr 3:117,250,096...117,316,200 		JBrowse link
G APOC3 apolipoprotein C3 acts_upstream_of_or_within ISO (MGI:82330|PMID:8864964)
(MGI:2152463|PMID:11590213), (MGI:69667|PMID:8089130)		 MGI PMID:8089130 PMID:8864964 PMID:11590213 MGI:2152463 MGI:69667 MGI:82330 NCBI chr 9:44,211,171...44,213,538
Ensembl chr 9:44,211,194...44,213,533 		JBrowse link
G APOE apolipoprotein E acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2180727|PMID:8647961), (MGI:51330|PMID:1423598) MGI
Ensembl		 PMID:1423598 PMID:8647961 GO_REF:0000107 MGI:2180727 MGI:51330 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G APOF apolipoprotein F acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:5428098|PMID:22363685)
(PMID:21873635)		 MGI
GO_Central		 PMID:21873635 PMID:22363685 MGI:5428098 NCBI chr 5:21,759,670...21,760,753
Ensembl chr 5:21,759,475...21,760,815 		JBrowse link
G APP amyloid beta precursor protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3762423|PMID:17920016) MGI
Ensembl		 PMID:17920016 GO_REF:0000107 MGI:3762423 NCBI chr13:189,434,854...189,716,120
Ensembl chr13:189,435,094...189,716,056 		JBrowse link
G CAPN1 calpain 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 2:6,997,513...7,024,410
Ensembl chr 2:6,997,985...7,022,684 		JBrowse link
G CAT catalase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:53683|PMID:5087482) MGI
Ensembl		 PMID:5087482 GO_REF:0000107 MGI:53683 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3847596|PMID:18974039) MGI
Ensembl		 PMID:18974039 GO_REF:0000107 MGI:3847596 NCBI chr 6:43,083,200...43,085,884
Ensembl chr 6:43,083,207...43,085,836 		JBrowse link
G CH25H cholesterol 25-hydroxylase acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA
ISS		 (MGI:1316846|PMID:9852097)
(PMID:21873635)		 MGI
GO_Central
Ensembl
UniProt		 PMID:9852097 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:1316846 NCBI chr14:101,122,318...101,128,622
Ensembl chr14:101,123,398...101,125,593 		JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:166,107,895...166,126,054
Ensembl chr 1:166,107,228...166,126,808 		JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:33,282,524...33,325,598
Ensembl chr15:33,288,301...33,304,631 		JBrowse link
G CUBN cubilin involved_in IEA UniProt GO_REF:0000043 NCBI chr10:43,102,931...43,414,692
Ensembl chr10:43,102,946...43,414,758 		JBrowse link
G CYB5R3 cytochrome b5 reductase 3 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:6,146,230...6,170,209
Ensembl chr 5:6,146,276...6,170,202 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 involved_in IEA
IBA
ISS		 (PMID:21873635) UniProt
GO_Central
Ensembl		 PMID:21873635 GO_REF:0000024 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:1,365,725...1,373,138 JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 involved_in ISO
IBA		 (PMID:21873635) RGD
GO_Central		 PMID:2175615 PMID:21873635 RGD:1299597 NCBI chr15:120,809,886...120,852,196
Ensembl chr15:120,809,959...120,852,192 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 9:72,057,506...72,079,587
Ensembl chr 9:72,057,511...72,079,444 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:74,343,101...74,372,628
Ensembl chr 4:74,343,123...74,372,621 		JBrowse link
G DHCR24 24-dehydrocholesterol reductase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3614236|PMID:16407971) MGI
Ensembl		 PMID:16407971 GO_REF:0000107 MGI:3614236 NCBI chr 6:157,483,794...157,519,060
Ensembl chr 6:157,483,783...157,519,061 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase involved_in IEA UniProt GO_REF:0000043 NCBI chr 2:2,377,352...2,391,846
Ensembl chr 2:2,377,416...2,391,447 		JBrowse link
G EBP EBP cholestenol delta-isomerase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:42,670,592...42,678,571
Ensembl chr  X:42,670,633...42,678,570 		JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104
G ERLIN2 ER lipid raft associated 2 involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr15:48,643,722...48,662,648
Ensembl chr15:48,643,724...48,662,536 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6282138|PMID:28053990)
(MGI:5447601|PMID:22912762)		 MGI
Ensembl		 PMID:22912762 PMID:28053990 GO_REF:0000107 MGI:5447601 MGI:6282138 NCBI chr 6:68,667,651...68,682,629
Ensembl chr 6:68,669,153...68,682,623 		JBrowse link
G FDX1 ferredoxin 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107 NCBI chr 9:38,376,147...38,399,026
Ensembl chr 9:38,375,984...38,404,832 		JBrowse link
G FDXR ferredoxin reductase involved_in IEA UniProt GO_REF:0000041 NCBI chr12:6,372,224...6,382,769
Ensembl chr12:6,372,009...6,382,769 		JBrowse link
G FECH ferrochelatase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1930023|PMID:11160364) MGI
Ensembl		 PMID:11160364 GO_REF:0000107 MGI:1930023 NCBI chr 1:106,861,628...106,898,407
Ensembl chr 1:106,854,011...106,898,591 		JBrowse link
G FGL1 fibrinogen like 1 acts_upstream_of_or_within ISO (MGI:5505372|PMID:23483972) MGI PMID:23483972 MGI:5505372 NCBI chr17:5,546,931...5,596,434
Ensembl chr17:5,547,126...5,576,790 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA
ISS		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr 4:94,583,905...94,606,689
Ensembl chr 4:94,584,134...94,609,745 		JBrowse link
G GBA2 glucosylceramidase beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:236,456,238...236,467,887
Ensembl chr 1:236,455,240...236,468,210 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase involved_in IEA UniProt GO_REF:0000043 NCBI chr 2:84,380,245...84,401,117
Ensembl chr 2:84,380,224...84,402,957 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr16:27,936,225...27,957,261
Ensembl chr16:27,936,218...27,957,193 		JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:101,420,941...101,440,302
Ensembl chr 4:101,420,872...101,438,126 		JBrowse link
G HNF1A HNF1 homeobox A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1933035|PMID:11279518) MGI
Ensembl		 PMID:11279518 GO_REF:0000107 MGI:1933035 NCBI chr14:40,868,819...40,888,322
Ensembl chr14:40,868,676...40,888,328 		JBrowse link
G IL4 interleukin 4 involved_in ISO (MGI:2178917|PMID:11971948) UniProt PMID:11971948 MGI:2178917 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G INSIG1 insulin induced gene 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3603108|PMID:16100574) MGI
Ensembl
UniProt		 PMID:16100574 GO_REF:0000043 GO_REF:0000107 MGI:3603108 NCBI chr18:2,885,494...2,898,758
Ensembl chr18:2,885,612...2,898,767 		JBrowse link
G INSIG2 insulin induced gene 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3603108|PMID:16100574) MGI
Ensembl
UniProt		 PMID:16100574 GO_REF:0000043 GO_REF:0000107 MGI:3603108 NCBI chr15:23,676,684...23,699,591
Ensembl chr15:23,676,683...23,699,582 		JBrowse link
G LBR lamin B receptor involved_in IEA UniProt GO_REF:0000043 NCBI chr10:13,389,896...13,416,831
Ensembl chr10:13,386,946...13,416,759 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase involved_in
acts_upstream_of_or_within		 ISO
IEA
ISS		 (PMID:10559507)
(MGI:1096057|PMID:9300780)		 RGD
Ensembl
UniProt
MGI		 PMID:746355 PMID:9300780 PMID:10559507 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107 MGI:1096057 RGD:1581789 NCBI chr 6:28,550,356...28,553,561
Ensembl chr 6:28,550,358...28,553,566 		JBrowse link
G LDLR low density lipoprotein receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3696597|PMID:17071966) MGI
Ensembl
UniProt		 PMID:17071966 GO_REF:0000043 GO_REF:0000107 MGI:3696597 NCBI chr 2:69,828,348...69,864,823
Ensembl chr 2:69,828,332...69,864,827 		JBrowse link
G LEP leptin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3588626|PMID:15995171) MGI
Ensembl		 PMID:15995171 GO_REF:0000107 MGI:3588626 NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,323 		JBrowse link
G LEPR leptin receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3588626|PMID:15995171) MGI
Ensembl		 PMID:15995171 GO_REF:0000107 MGI:3588626 NCBI chr 6:146,802,297...146,896,152
Ensembl chr 6:146,801,954...146,895,995 		JBrowse link
G LIMA1 LIM domain and actin binding 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:16,074,436...16,177,122
Ensembl chr 5:16,074,438...16,177,103 		JBrowse link
G LIPA lipase A, lysosomal acid type acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5576805|PMID:24370824)
(MGI:6277301|PMID:30639734)		 MGI
Ensembl		 PMID:24370824 PMID:30639734 GO_REF:0000107 MGI:5576805 MGI:6277301 NCBI chr14:101,131,372...101,254,739
Ensembl chr14:101,126,257...101,193,614 		JBrowse link
G LIPC lipase C, hepatic type acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1339279|PMID:10357838) MGI
Ensembl		 PMID:10357838 GO_REF:0000107 MGI:1339279 NCBI chr 1:113,433,684...113,604,139
Ensembl chr 1:113,433,687...113,583,963 		JBrowse link
G LIPE lipase E, hormone sensitive type involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 6:49,543,671...49,560,126
Ensembl chr 6:49,540,708...49,560,125 		JBrowse link
G LOC100625049 isopentenyl-diphosphate Delta-isomerase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:68,534,520...68,539,279
Ensembl chr10:68,534,796...68,539,280 		JBrowse link
G LOC110255234 liver carboxylesterase-like involved_in IEA Ensembl GO_REF:0000107
G LOC110260333 hydroxymethylglutaryl-CoA synthase, mitochondrial-like involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:101,385,486...101,404,273
Ensembl chr 4:101,385,512...101,443,405 		JBrowse link
G LRP1 LDL receptor related protein 1 acts_upstream_of_or_within ISO (MGI:3762423|PMID:17920016) MGI PMID:17920016 MGI:3762423 NCBI chr 5:22,435,636...22,519,276 JBrowse link
G LRP5 LDL receptor related protein 5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2448205|PMID:12509515) MGI
Ensembl		 PMID:12509515 GO_REF:0000107 MGI:2448205 NCBI chr 2:4,533,721...4,653,997
Ensembl chr 2:4,533,614...4,653,944 		JBrowse link
G MSMO1 methylsterol monooxygenase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 8:43,726,834...43,745,784
Ensembl chr 8:43,726,858...43,744,713 		JBrowse link
G MVD mevalonate diphosphate decarboxylase involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:1,008,100...1,014,303
Ensembl chr 6:1,008,100...1,014,303 		JBrowse link
G MVK mevalonate kinase involved_in IEA UniProt GO_REF:0000043 NCBI chr14:41,320,790...41,357,437
Ensembl chr14:41,281,673...41,357,368 		JBrowse link
G NPC1 NPC intracellular cholesterol transporter 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:108,403,126...108,450,486
Ensembl chr 6:108,402,879...108,450,990 		JBrowse link
G NPC2 NPC intracellular cholesterol transporter 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 7:97,730,532...97,740,087
Ensembl chr 7:97,730,516...97,740,331 		JBrowse link
G NSDHL NAD(P) dependent steroid dehydrogenase-like acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (MGI:1338572|PMID:10369263)
(PMID:21873635)		 MGI
GO_Central
Ensembl		 PMID:10369263 PMID:21873635 GO_REF:0000107 MGI:1338572 NCBI chr  X:123,906,130...123,921,935
Ensembl chr  X:123,906,199...123,929,117 		JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3710922|PMID:17242417) MGI
Ensembl
UniProt		 PMID:17242417 GO_REF:0000043 GO_REF:0000107 MGI:3710922 NCBI chr 6:157,388,370...157,409,620
Ensembl chr 6:157,388,372...157,409,551 		JBrowse link
G PCTP phosphatidylcholine transfer protein acts_upstream_of_or_within ISO (MGI:3603484|PMID:15845870) MGI PMID:15845870 MGI:3603484 NCBI chr12:32,043,841...32,089,977 JBrowse link
G PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:78,447,323...78,451,761
Ensembl chr 7:78,447,369...78,451,846 		JBrowse link
G PMP22 peripheral myelin protein 22 acts_upstream_of_or_within ISO (MGI:5616959|PMID:25429154) MGI PMID:25429154 MGI:5616959 NCBI chr12:58,679,773...58,734,195
Ensembl chr12:58,679,775...58,707,925 		JBrowse link
G PMVK phosphomevalonate kinase involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:94,861,500...94,913,743
Ensembl chr 4:94,861,712...94,874,771 		JBrowse link
G PON1 paraoxonase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1860864|PMID:9685159) MGI
Ensembl		 PMID:9685159 GO_REF:0000107 MGI:1860864 NCBI chr 9:74,943,646...74,974,720
Ensembl chr 9:74,926,048...74,974,723 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr16:25,745,902...25,783,524
Ensembl chr16:25,745,324...25,783,707 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:155,683,392...155,754,283
Ensembl chr 6:155,681,784...155,754,278 		JBrowse link
G SCAP SREBF chaperone acts_upstream_of_or_within
involved_in		 ISO
IEA
ISS		 (MGI:1934968|PMID:11358865) MGI
UniProt
Ensembl		 PMID:11358865 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107 MGI:1934968 NCBI chr13:30,253,262...30,320,625
Ensembl chr13:30,253,268...30,320,526 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5320806|PMID:22383528) MGI
Ensembl		 PMID:22383528 GO_REF:0000107 MGI:5320806 NCBI chr 9:3,324,091...3,328,493
Ensembl chr 9:3,324,442...3,328,457 		JBrowse link
G SOAT1 sterol O-acyltransferase 1 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (MGI:3603484|PMID:15845870)
(PMID:21873635)
(PMID:9756919)		 MGI
GO_Central
UniProt
Ensembl		 PMID:9756919 PMID:15845870 PMID:21873635 GO_REF:0000043 GO_REF:0000107 MGI:3603484 NCBI chr 9:121,045,211...121,112,393
Ensembl chr 9:121,045,234...121,113,692 		JBrowse link
G SOAT2 sterol O-acyltransferase 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (MGI:1206070|PMID:9756919) RGD
Ensembl
UniProt
MGI		 PMID:9756919 PMID:12217884 GO_REF:0000043 GO_REF:0000107 MGI:1206070 RGD:625687 NCBI chr 5:18,358,941...18,371,262
Ensembl chr 5:18,358,673...18,371,264 		JBrowse link
G SQLE squalene epoxidase involved_in ISO
IBA		 (PMID:21873635) RGD
GO_Central		 PMID:9300786 PMID:21873635 RGD:1625701 NCBI chr 4:14,669,789...14,700,152
Ensembl chr 4:14,669,791...14,700,126 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in ISO
IEA		 RGD
UniProt		 PMID:18071061 GO_REF:0000043 RGD:1643359 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267 		JBrowse link
G STAR steroidogenic acute regulatory protein involved_in IEA UniProt GO_REF:0000041 NCBI chr15:48,377,597...48,385,398
Ensembl chr15:48,377,521...48,385,462 		JBrowse link
G SULT1C3 sulfotransferase family 1C member 3 involved_in ISO (PMID:28992322) UniProt PMID:28992322 NCBI chr 3:47,838,671...47,864,646
Ensembl chr 3:47,838,558...47,856,943 		JBrowse link
G SULT2A1 sulfotransferase family 2A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:53,525,496...53,536,723
Ensembl chr 6:53,524,787...53,536,718 		JBrowse link
G SULT2B1 sulfotransferase family 2B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:53,928,248...53,963,443
Ensembl chr 6:53,928,248...53,963,443 		JBrowse link
G TM7SF2 transmembrane 7 superfamily member 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 2:7,076,778...7,081,502
Ensembl chr 2:7,075,068...7,081,432 		JBrowse link
G TNFSF4 TNF superfamily member 4 acts_upstream_of_or_within ISO (MGI:57200|PMID:3473481) MGI PMID:3473481 MGI:57200 NCBI chr 9:115,535,185...115,857,457
Ensembl chr 9:115,550,569...115,659,263 		JBrowse link
G TSKU tsukushi, small leucine rich proteoglycan involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:10,927,224...10,940,851
Ensembl chr 9:10,927,342...10,942,668 		JBrowse link
G TTC22 tetratricopeptide repeat domain 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:157,555,204...157,579,299
Ensembl chr 6:157,556,184...157,579,161 		JBrowse link
cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2180727|PMID:8647961) MGI
Ensembl		 PMID:8647961 GO_REF:0000107 MGI:2180727 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,392...44,218,713 		JBrowse link
G CAPN1 calpain 1 involved_in IEA UniProt GO_REF:0000041 GO_REF:0000043 NCBI chr 2:6,997,513...7,024,410
Ensembl chr 2:6,997,985...7,022,684 		JBrowse link
G CFTR CF transmembrane conductance regulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3709533|PMID:17085523) MGI
Ensembl		 PMID:17085523 GO_REF:0000107 MGI:3709533 NCBI chr18:28,627,717...28,818,209
Ensembl chr18:28,627,728...28,817,950 		JBrowse link
G CYB5R3 cytochrome b5 reductase 3 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:6,146,230...6,170,209
Ensembl chr 5:6,146,276...6,170,202 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 9:72,057,506...72,079,587
Ensembl chr 9:72,057,511...72,079,444 		JBrowse link
G DHCR24 24-dehydrocholesterol reductase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2686848|PMID:14684813), (MGI:3624168|PMID:16321981), (MGI:3769949|PMID:16513830)
(PMID:11519011)		 MGI
Ensembl		 PMID:11519011 PMID:14684813 PMID:16321981 PMID:16513830 GO_REF:0000107 MGI:2686848 MGI:3624168 MGI:3769949 NCBI chr 6:157,483,794...157,519,060
Ensembl chr 6:157,483,783...157,519,061 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase involved_in ISO
IBA
IEA		 (PMID:21873635) RGD
GO_Central
UniProt
Ensembl		 PMID:9831636 PMID:10329655 PMID:21873635 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 RGD:2316918 RGD:632010 NCBI chr 2:2,377,352...2,391,846
Ensembl chr 2:2,377,416...2,391,447 		JBrowse link
G EBP EBP cholestenol delta-isomerase involved_in ISO
IEA
IBA		 (PMID:21873635) RGD
Ensembl
GO_Central		 PMID:11171067 PMID:21873635 GO_REF:0000107 RGD:628445 NCBI chr  X:42,670,592...42,678,571
Ensembl chr  X:42,670,633...42,678,570 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 involved_in ISO
IBA		 (PMID:21873635) RGD
GO_Central		 PMID:16440058 PMID:21873635 RGD:1626611 NCBI chr14:14,976,259...15,010,701
Ensembl chr14:14,967,074...15,016,227 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:125,029,147...125,041,040
Ensembl chr  X:125,029,150...125,041,040 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2180727|PMID:8647961), (MGI:3603484|PMID:15845870), (MGI:70238|PMID:7798939) MGI
Ensembl
UniProt		 PMID:7798939 PMID:8647961 PMID:15845870 GO_REF:0000043 GO_REF:0000107 MGI:2180727 MGI:3603484 MGI:70238 NCBI chr 2:84,380,245...84,401,117
Ensembl chr 2:84,380,224...84,402,957 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr16:27,936,225...27,957,261
Ensembl chr16:27,936,218...27,957,193 		JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:101,420,941...101,440,302
Ensembl chr 4:101,420,872...101,438,126 		JBrowse link
G HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2673751|PMID:12829805) MGI
Ensembl		 PMID:12829805 GO_REF:0000107 MGI:2673751 NCBI chr 4:87,720,747...87,743,037
Ensembl chr 4:87,720,118...87,742,992 		JBrowse link
G INSIG1 insulin induced gene 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3689278|PMID:16955138) MGI
Ensembl		 PMID:16955138 GO_REF:0000107 MGI:3689278 NCBI chr18:2,885,494...2,898,758
Ensembl chr18:2,885,612...2,898,767 		JBrowse link
G INSIG2 insulin induced gene 2 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA
ISS		 (MGI:3689278|PMID:16955138)
(PMID:21873635)		 MGI
Ensembl
GO_Central
UniProt		 PMID:16955138 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:3689278 NCBI chr15:23,676,684...23,699,591
Ensembl chr15:23,676,683...23,699,582 		JBrowse link
G LBR lamin B receptor involved_in IEA
IBA		 (PMID:21873635) UniProt
GO_Central
Ensembl		 PMID:21873635 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr10:13,389,896...13,416,831
Ensembl chr10:13,386,946...13,416,759 		JBrowse link
G LIPA lipase A, lysosomal acid type acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5702564|PMID:25147230), (MGI:6385435|PMID:29599133) MGI
Ensembl		 PMID:25147230 PMID:29599133 GO_REF:0000107 MGI:5702564 MGI:6385435 NCBI chr14:101,131,372...101,254,739
Ensembl chr14:101,126,257...101,193,614 		JBrowse link
G LOC100625049 isopentenyl-diphosphate Delta-isomerase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:68,534,520...68,539,279
Ensembl chr10:68,534,796...68,539,280 		JBrowse link
G LOC110255234 liver carboxylesterase-like involved_in IEA Ensembl GO_REF:0000107
G LOC110260333 hydroxymethylglutaryl-CoA synthase, mitochondrial-like involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:101,385,486...101,404,273
Ensembl chr 4:101,385,512...101,443,405 		JBrowse link
G LSS lanosterol synthase involved_in ISO
IEA
IBA		 (PMID:21873635) RGD
Ensembl
GO_Central		 PMID:1429550 PMID:16440058 PMID:21873635 GO_REF:0000107 RGD:1626611 RGD:2316919
G MSMO1 methylsterol monooxygenase 1 involved_in IEA UniProt GO_REF:0000041 GO_REF:0000043 NCBI chr 8:43,726,834...43,745,784
Ensembl chr 8:43,726,858...43,744,713 		JBrowse link
G MVD mevalonate diphosphate decarboxylase involved_in IEA UniProt GO_REF:0000041 GO_REF:0000043 NCBI chr 6:1,008,100...1,014,303
Ensembl chr 6:1,008,100...1,014,303 		JBrowse link
G MVK mevalonate kinase involved_in IEA
IBA		 (PMID:21873635) UniProt
Ensembl
GO_Central		 PMID:21873635 GO_REF:0000043 GO_REF:0000107 NCBI chr14:41,320,790...41,357,437
Ensembl chr14:41,281,673...41,357,368 		JBrowse link
G NPC1L1 NPC1 like intracellular cholesterol transporter 1 involved_in ISO (PMID:17140581) HGNC-UCL PMID:17140581 NCBI chr18:50,726,854...50,757,676
Ensembl chr18:50,726,922...50,757,649 		JBrowse link
G PMVK phosphomevalonate kinase involved_in IEA
ISS
IBA		 (PMID:8663599)
(PMID:21873635)		 InterPro
UniProt
Ensembl
GO_Central		 PMID:8663599 PMID:21873635 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr 4:94,861,500...94,913,743
Ensembl chr 4:94,861,712...94,874,771 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr16:25,745,902...25,783,524
Ensembl chr16:25,745,324...25,783,707 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:155,683,392...155,754,283
Ensembl chr 6:155,681,784...155,754,278 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:1098057|PMID:9329978) MGI
Ensembl		 PMID:9329978 GO_REF:0000107 MGI:1098057 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267 		JBrowse link
G TM7SF2 transmembrane 7 superfamily member 2 involved_in IEA Ensembl
UniProt		 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr 2:7,076,778...7,081,502
Ensembl chr 2:7,075,068...7,081,432 		JBrowse link
G TTC22 tetratricopeptide repeat domain 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:157,555,204...157,579,299
Ensembl chr 6:157,556,184...157,579,161 		JBrowse link
cholesterol biosynthetic process via 24,25-dihydrolanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 ISO RGD PMID:7581240 RGD:2316902 NCBI chr 9:72,057,506...72,079,587
Ensembl chr 9:72,057,511...72,079,444 		JBrowse link
cholesterol biosynthetic process via desmosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHCR24 24-dehydrocholesterol reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:157,483,794...157,519,060
Ensembl chr 6:157,483,783...157,519,061 		JBrowse link
G TTC22 tetratricopeptide repeat domain 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:157,555,204...157,579,299
Ensembl chr 6:157,556,184...157,579,161 		JBrowse link
cholesterol biosynthetic process via lathosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SC5D sterol-C5-desaturase ISO RGD PMID:7961720 RGD:2316911 NCBI chr 9:48,357,115...48,372,391
Ensembl chr 9:48,357,165...48,372,386 		JBrowse link
cholesterol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1D1 aldo-keto reductase family 1 member D1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:11,416,065...11,532,846
Ensembl chr18:11,416,068...11,531,726 		JBrowse link
G APOE apolipoprotein E acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 (MGI:1314982|PMID:9826706)
(PMID:21873635)		 MGI
Ensembl
GO_Central		 PMID:9826706 PMID:21873635 GO_REF:0000107 MGI:1314982 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:120,809,886...120,852,196
Ensembl chr15:120,809,959...120,852,192 		JBrowse link
G CYP39A1 cytochrome P450 family 39 subfamily A member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1859119|PMID:10748047) MGI
Ensembl		 PMID:10748047 GO_REF:0000107 MGI:1859119 NCBI chr 7:41,345,011...41,425,854
Ensembl chr 7:41,344,804...41,425,997 		JBrowse link
G CYP46A1 cytochrome P450 family 46 subfamily A member 1 involved_in IEA
IBA		 (PMID:21873635) InterPro
GO_Central
Ensembl		 PMID:21873635 GO_REF:0000002 GO_REF:0000107 NCBI chr 7:120,658,781...120,695,031
Ensembl chr 7:120,661,111...120,695,016 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA
ISS		 (MGI:1933035|PMID:11279518), (MGI:3603484|PMID:15845870) MGI
UniProt
Ensembl
InterPro		 PMID:11279518 PMID:15845870 GO_REF:0000002 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 MGI:1933035 MGI:3603484 NCBI chr 4:74,343,101...74,372,628
Ensembl chr 4:74,343,123...74,372,621 		JBrowse link
G SCARB1 scavenger receptor class B member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3690692|PMID:10559220)
(MGI:1934548|PMID:11278646)		 MGI
Ensembl		 PMID:10559220 PMID:11278646 GO_REF:0000107 MGI:1934548 MGI:3690692 NCBI chr14:28,301,421...28,393,568
Ensembl chr14:28,301,294...28,393,568 		JBrowse link
G STX1B syntaxin 1B ISO RGD PMID:16081591 RGD:1599972 NCBI chr 3:17,439,563...17,459,517
Ensembl chr 3:17,439,581...17,459,516 		JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO
IEA		 RGD
Ensembl		 PMID:9225228 GO_REF:0000107 RGD:10059686 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:48,643,722...48,662,648
Ensembl chr15:48,643,724...48,662,536 		JBrowse link
G LOC110258909 isopentenyl-diphosphate Delta-isomerase 1-like acts_upstream_of_or_within ISO (MGI:5490819|PMID:17202134) MGI PMID:17202134 MGI:5490819
G MIR185 microRNA mir-185 acts_upstream_of ISO (PMID:24296663)
(PMID:23951060)		 BHF-UCL PMID:23951060 PMID:24296663 NCBI chr14:51,449,903...51,449,978
Ensembl chr14:51,449,903...51,449,978 		JBrowse link
G MIR342 microRNA mir-342 acts_upstream_of ISO (PMID:23951060) BHF-UCL PMID:23951060 NCBI chr 7:121,021,761...121,021,840
Ensembl chr 7:121,021,761...121,021,840 		JBrowse link
G MIR98 microRNA mir-98 involved_in ISO (PMID:30195495) BHF-UCL PMID:30195495 NCBI chr  X:46,302,381...46,302,460
Ensembl chr  X:46,302,381...46,302,460 		JBrowse link
G SOD1 superoxide dismutase 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729 		JBrowse link
negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CH25H cholesterol 25-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:101,122,318...101,128,622
Ensembl chr14:101,123,398...101,125,593 		JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3768186|PMID:17916878) BHF-UCL PMID:17916878 MGI:3768186 NCBI chr13:205,561,897...205,628,428
Ensembl chr13:205,561,951...205,628,425 		JBrowse link
G ABCG4 ATP binding cassette subfamily G member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:46,364,546...46,380,545
Ensembl chr 9:46,364,936...46,380,544 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 4:74,343,101...74,372,628
Ensembl chr 4:74,343,123...74,372,621 		JBrowse link
G FDPS farnesyl diphosphate synthase ISO RGD PMID:18637708 RGD:2316295 NCBI chr 4:94,500,140...94,514,820
Ensembl chr 4:94,500,141...94,518,408 		JBrowse link
G FGF1 fibroblast growth factor 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:144,133,846...144,241,345
Ensembl chr 2:144,133,392...144,241,323 		JBrowse link
G MIR96 microRNA mir-96 involved_in
acts_upstream_of		 ISO (PMID:23823476)
(PMID:30460077)		 BHF-UCL PMID:23823476 PMID:30460077 NCBI chr18:18,982,506...18,982,590
Ensembl chr18:18,982,506...18,982,590 		JBrowse link
G POR cytochrome p450 oxidoreductase ISO RGD PMID:19264869 RGD:2316785 NCBI chr 3:10,212,734...10,272,184
Ensembl chr 3:10,212,735...10,281,823 		JBrowse link
G QKI QKI, KH domain containing RNA binding involved_in ISO (MGI:6712091|PMID:33942715) UniProt PMID:33942715 MGI:6712091 NCBI chr 1:4,732,575...4,883,386
Ensembl chr 1:4,735,514...4,883,392 		JBrowse link
G SCAP SREBF chaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:30,253,262...30,320,625
Ensembl chr13:30,253,268...30,320,526 		JBrowse link
G SCP2 sterol carrier protein 2 ISO RGD PMID:2554812 RGD:9850260 NCBI chr 6:159,191,045...159,314,985 JBrowse link
G SEC14L2 SEC14 like lipid binding 2 ISO RGD PMID:11226224 RGD:727312 NCBI chr14:47,369,663...47,391,335
Ensembl chr14:47,370,055...47,392,499 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 acts_upstream_of_or_within
involved_in		 ISO
ISS
IEA		 (MGI:3603730|PMID:16046411)
(MGI:1098057|PMID:9329978)		 MGI
UniProt
Ensembl		 PMID:9329978 PMID:16046411 GO_REF:0000024 GO_REF:0000107 MGI:1098057 MGI:3603730 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:6,719,484...6,784,724
Ensembl chr 5:6,719,490...6,784,671 		JBrowse link
positive regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,392...44,218,713 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G LOC110255234 liver carboxylesterase-like involved_in IEA Ensembl GO_REF:0000107
G STARD4 StAR related lipid transfer domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:116,235,821...116,257,143
Ensembl chr 2:116,236,255...116,257,041 		JBrowse link
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 NOT|involved_in ISO (PMID:21810484) ARUK-UCL PMID:21810484
G APOB apolipoprotein B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3652707|PMID:16455790) MGI
Ensembl		 PMID:16455790 GO_REF:0000107 MGI:3652707 NCBI chr 3:117,250,096...117,316,200
Ensembl chr 3:117,250,096...117,316,200 		JBrowse link
G AQP8 aquaporin 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:21,493,564...21,503,778
Ensembl chr 3:21,491,719...21,503,863 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase ISO RGD PMID:10329655 RGD:632010 NCBI chr 2:2,377,352...2,391,846
Ensembl chr 2:2,377,416...2,391,447 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:48,643,722...48,662,648
Ensembl chr15:48,643,724...48,662,536 		JBrowse link
G LPCAT3 lysophosphatidylcholine acyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:63,707,674...63,746,369
Ensembl chr 5:63,708,020...63,746,103 		JBrowse link
G PEX2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO (MGI:3027293|PMID:14673138) MGI PMID:14673138 MGI:3027293 NCBI chr 4:59,252,330...59,270,117
Ensembl chr 4:59,252,337...59,270,116 		JBrowse link
G SCAP SREBF chaperone acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (MGI:3770209|PMID:16054043)
(PMID:21873635)		 MGI
GO_Central
Ensembl		 PMID:16054043 PMID:21873635 GO_REF:0000107 MGI:3770209 NCBI chr13:30,253,262...30,320,625
Ensembl chr13:30,253,268...30,320,526 		JBrowse link
regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852) BHF-UCL PMID:16556852 MGI:3852307 NCBI chr13:205,561,897...205,628,428
Ensembl chr13:205,561,951...205,628,425 		JBrowse link
G ACADL acyl-CoA dehydrogenase long chain involved_in ISO (MGI:3526480|PMID:15639194) BHF-UCL PMID:15639194 MGI:3526480 NCBI chr15:112,935,631...112,969,381
Ensembl chr15:112,933,506...112,969,577 		JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,573,521...52,581,755
Ensembl chr12:52,576,402...52,581,748 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G ARV1 ARV1 homolog, fatty acid homeostasis modulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4849624|PMID:20663892) MGI
Ensembl		 PMID:20663892 GO_REF:0000107 MGI:4849624 NCBI chr14:59,396,958...59,409,008
Ensembl chr14:59,396,962...59,408,958 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 ISO RGD PMID:17526931 RGD:10400884 NCBI chr 9:10,032,163...10,066,082
Ensembl chr 9:10,032,128...10,068,437 		JBrowse link
G DGKQ diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:313,325...325,089
Ensembl chr 8:313,329...325,095 		JBrowse link
G EPHX2 epoxide hydrolase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:11,217,125...11,293,018
Ensembl chr14:11,216,978...11,293,410 		JBrowse link
G FMO5 flavin containing dimethylaniline monoxygenase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:100,336,769...100,372,744
Ensembl chr 4:100,336,980...100,374,367 		JBrowse link
G GNB3 G protein subunit beta 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:63,863,656...63,871,352
Ensembl chr 5:63,863,661...63,870,433 		JBrowse link
G LDLR low density lipoprotein receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:69,828,348...69,864,823
Ensembl chr 2:69,828,332...69,864,827 		JBrowse link
G LMF1 lipase maturation factor 1 acts_upstream_of_or_within ISO (MGI:55554|PMID:6857276) MGI PMID:6857276 MGI:55554 NCBI chr 3:40,841,242...40,929,163
Ensembl chr 3:40,835,413...40,934,253 		JBrowse link
G LOC106504546 serpin A12 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5563627|PMID:22837305) MGI
Ensembl		 PMID:22837305 GO_REF:0000107 MGI:5563627 NCBI chr 7:115,720,892...115,734,810
Ensembl chr 7:115,721,098...115,734,978 		JBrowse link
G POR cytochrome p450 oxidoreductase ISO RGD PMID:19264869 RGD:2316785 NCBI chr 3:10,212,734...10,272,184
Ensembl chr 3:10,212,735...10,281,823 		JBrowse link
G THRB thyroid hormone receptor beta ISO RGD PMID:17878314 RGD:2315101 NCBI chr13:10,900,716...11,360,587
Ensembl chr13:10,900,724...11,359,544 		JBrowse link
G TTC39B tetratricopeptide repeat domain 39B involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr 1:207,347,345...207,490,753
Ensembl chr 1:207,347,360...207,495,965 		JBrowse link
G TTC39D tetratricopeptide repeat domain 39D involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:101,577,184...101,580,487 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17412
    metabolic process 10286
      small molecule metabolic process 1700
        alcohol metabolic process 332
          secondary alcohol metabolic process 144
            cholesterol metabolic process 131
              cholesterol biosynthetic process + 57
              cholesterol catabolic process 8
              cholesterol ester hydrolysis involved in cholesterol transport 0
              negative regulation of cholesterol metabolic process + 8
              peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine 0
              positive regulation of cholesterol metabolic process + 17
              regulation of cholesterol metabolic process + 44
Path 2
Term Annotations click to browse term
  biological_process 17412
    metabolic process 10286
      primary metabolic process 8738
        lipid metabolic process 1266
          steroid metabolic process 292
            sterol metabolic process 136
              cholesterol metabolic process 131
                cholesterol biosynthetic process + 57
                cholesterol catabolic process 8
                cholesterol ester hydrolysis involved in cholesterol transport 0
                negative regulation of cholesterol metabolic process + 8
                peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine 0
                positive regulation of cholesterol metabolic process + 17
                regulation of cholesterol metabolic process + 44
paths to the root