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ONTOLOGY REPORT - ANNOTATIONS


Term:cholesterol metabolic process
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Accession:GO:0008203 term browser browse the term
Definition:The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.
Synonyms:exact_synonym: cholesterol metabolism
 never_in_taxon: NCBITaxon:4895 ! Schizosaccharomyces;   NCBITaxon:4930 ! Saccharomyces



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cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 involved_in
acts_upstream_of_or_within
ISO (PMID:14747463)
(MGI:2153573|PMID:11559713)
RGD PMID:11559713 PMID:14747463 MGI:2153573 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abca5 ATP binding cassette subfamily A member 5 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:25125465)
UniProt
Ensembl
RGD
PMID:25125465 GO_REF:0000024 GO_REF:0000107 NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:15994327) RGD PMID:15994327 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Angptl3 angiopoietin-like 3 involved_in ISO (PMID:17110602) RGD PMID:17110602 NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957
JBrowse link
G Aplp2 amyloid beta precursor like protein 2 acts_upstream_of_or_within ISO MGI:88059 (MGI:3762423|PMID:17920016) RGD PMID:17920016 MGI:3762423 NCBI chr 8:29,599,230...29,662,311
Ensembl chr 8:29,599,230...29,661,855
JBrowse link
G Apoa1 apolipoprotein A1 involved_in
acts_upstream_of_or_within
ISO (PMID:15464323)
MGI:104663|MGI:104993|MGI:1857127 (MGI:1099137|PMID:9327769), (MGI:1339278|PMID:10357841), (MGI:3487338|PMID:15466405), (MGI:3588626|PMID:15995171), (MGI:3688492|PMID:9795222), (MGI:3696597|PMID:17071966), (MGI:70854|PMID:7751823)
RGD PMID:7751823 PMID:9327769 PMID:9795222 PMID:10357841 PMID:15464323 More... MGI:1099137 MGI:1339278 MGI:3487338 MGI:3588626 MGI:3688492 MGI:3696597 MGI:70854 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2157148|MGI:96216 (MGI:1339279|PMID:10357838), (MGI:2180727|PMID:8647961)
RGD PMID:8647961 PMID:10357838 PMID:21873635 MGI:1339279 MGI:2180727, RGD:13792537 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa4 apolipoprotein A4 involved_in IEA
ISO
GO_REF:0000107
(PMID:1935934)
Ensembl
RGD
PMID:1935934 GO_REF:0000107 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apob apolipoprotein B involved_in ISO (PMID:2563166) RGD PMID:2563166 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoc1 apolipoprotein C1 acts_upstream_of_or_within ISO MGI:2157218 (MGI:70746|PMID:7848292) RGD PMID:7848292 MGI:70746 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
G Apoc3 apolipoprotein C3 acts_upstream_of_or_within ISO MGI:1857128|MGI:3758464 (MGI:2152463|PMID:11590213), (MGI:69667|PMID:8089130), (MGI:82330|PMID:8864964) RGD PMID:8089130 PMID:8864964 PMID:11590213 MGI:2152463 MGI:69667 MGI:82330 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Apoe apolipoprotein E involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2137814 (MGI:2180727|PMID:8647961), (MGI:51330|PMID:1423598)
(PMID:3771793), (PMID:9649566)
Ensembl
RGD
PMID:1423598 PMID:3771793 PMID:8647961 PMID:9649566 GO_REF:0000107 MGI:2180727 MGI:51330 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apof apolipoprotein F involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3800154 (MGI:5428098|PMID:22363685)
RGD PMID:22363685 PMID:21873635 MGI:5428098, RGD:13792537 NCBI chr 7:700,688...702,130
Ensembl chr 7:700,762...701,946
JBrowse link
G Apon apolipoprotein N involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:686,943...688,346
Ensembl chr 7:686,927...688,392
JBrowse link
G App amyloid beta precursor protein acts_upstream_of_or_within ISO MGI:2136847|MGI:88047 (MGI:3762423|PMID:17920016) RGD PMID:17920016 MGI:3762423 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Cat catalase acts_upstream_of_or_within ISO MGI:3053604 (MGI:53683|PMID:5087482) RGD PMID:5087482 MGI:53683 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3848341 (MGI:3847596|PMID:18974039)
Ensembl
RGD
PMID:18974039 GO_REF:0000107 MGI:3847596 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Ces1d carboxylesterase 1D involved_in ISO (PMID:16024911) RGD PMID:16024911 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Ch25h cholesterol 25-hydroxylase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1316846|PMID:9852097)
RGD PMID:9852097 PMID:21873635 MGI:1316846, RGD:13792537 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195
JBrowse link
G Cln6 CLN6, transmembrane ER protein involved_in ISO (PMID:16857350) RGD PMID:16857350 NCBI chr 8:63,303,356...63,318,360
Ensembl chr 8:63,303,029...63,318,360
JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein involved_in ISS
ISO
GO_REF:0000024
(PMID:16086686)
UniProt
RGD
PMID:16086686 GO_REF:0000024 NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774
JBrowse link
G Cubn cubilin involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 involved_in IBA
ISO
ISS
IEA
PMID:21873635
(PMID:18182448), (PMID:21636783)
GO_REF:0000024
GO_REF:0000041
RGD
UniProt
PMID:18182448 PMID:21636783 PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:106,772,597...106,780,536
Ensembl chr 7:106,718,274...106,779,278
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:2175615 PMID:21873635 RGD:1299597, RGD:13792537 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 TAS RGD PMID:12029625 RGD:1298868 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase acts_upstream_of_or_within ISO MGI:3027024 (MGI:3614236|PMID:16407971) RGD PMID:16407971 MGI:3614236 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671
JBrowse link
G Fdx1 ferredoxin 1 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:21636783)
Ensembl
UniProt
RGD
PMID:21636783 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414
JBrowse link
G Fdxr ferredoxin reductase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658
JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within ISO MGI:1858114 (MGI:1930023|PMID:11160364) RGD PMID:11160364 MGI:1930023 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
G Fgl1 fibrinogen-like 1 acts_upstream_of_or_within ISO MGI:5510996 (MGI:5505372|PMID:23483972) RGD PMID:23483972 MGI:5505372 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093
JBrowse link
G Gba glucosylceramidase beta involved_in ISO
IEA
(PMID:24211208), (PMID:26724485)
(MGI:6271235|PMID:24211208)
GO_REF:0000041
RGD
UniProt
PMID:24211208 PMID:26724485 GO_REF:0000041 MGI:6271235 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Gba2 glucosylceramidase beta 2 involved_in IEA
ISO
ISS
GO_REF:0000041
(MGI:5771619|PMID:26724485)
GO_REF:0000024
UniProt
RGD
PMID:26724485 GO_REF:0000024 GO_REF:0000041 MGI:5771619 NCBI chr 5:57,822,389...57,834,522
Ensembl chr 5:57,822,389...57,834,072
JBrowse link
G Hdlbp high density lipoprotein binding protein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 9:93,948,099...94,018,040
Ensembl chr 9:93,949,913...94,018,048
JBrowse link
G Hnf1a HNF1 homeobox A acts_upstream_of_or_within ISO MGI:2384427 (MGI:1933035|PMID:11279518) RGD PMID:11279518 MGI:1933035 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 NAS RGD PMID:8913347 RGD:632889 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Il4 interleukin 4 involved_in ISO (MGI:2178917|PMID:11971948) RGD PMID:11971948 MGI:2178917 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO MGI:1920249 (MGI:3603108|PMID:16100574) RGD PMID:16100574 MGI:3603108 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within ISO MGI:1916289 (MGI:3603108|PMID:16100574) RGD PMID:16100574 MGI:3603108 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
JBrowse link
G Lcat lecithin cholesterol acyltransferase acts_upstream_of_or_within
involved_in
IDA
ISO
(PMID:10559507)
(PMID:26195816), (PMID:4335615)
(MGI:1096057|PMID:9300780)
RGD PMID:4335615 PMID:9300780 PMID:10559507 PMID:26195816 PMID:746355 MGI:1096057, RGD:1581789 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Ldlr low density lipoprotein receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857212 (MGI:3696597|PMID:17071966)
Ensembl
RGD
PMID:17071966 GO_REF:0000107 MGI:3696597 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601
JBrowse link
G Lep leptin acts_upstream_of_or_within ISO MGI:88049 (MGI:3588626|PMID:15995171) RGD PMID:15995171 MGI:3588626 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepr leptin receptor acts_upstream_of_or_within ISO MGI:88049 (MGI:3588626|PMID:15995171) RGD PMID:15995171 MGI:3588626 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lima1 LIM domain and actin binding 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:130,901,717...131,001,573
Ensembl chr 7:130,901,717...131,001,473
JBrowse link
G Lipc lipase C, hepatic type involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:88050 (MGI:1339279|PMID:10357838)
Ensembl
RGD
PMID:10357838 GO_REF:0000107 MGI:1339279 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lipe lipase E, hormone sensitive type involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
JBrowse link
G Lrp1 LDL receptor related protein 1 acts_upstream_of_or_within ISO MGI:2177650|MGI:2180880 (MGI:3762423|PMID:17920016) RGD PMID:17920016 MGI:3762423 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Lrp5 LDL receptor related protein 5 acts_upstream_of_or_within ISO MGI:2448955 (MGI:2448205|PMID:12509515) RGD PMID:12509515 MGI:2448205 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr19:47,561,598...47,612,769
Ensembl chr19:47,561,598...47,612,791
JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1857776 (MGI:1338572|PMID:10369263)
RGD PMID:10369263 PMID:21873635 MGI:1338572, RGD:13792537 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 acts_upstream_of_or_within ISO (MGI:3710922|PMID:17242417) RGD PMID:17242417 MGI:3710922 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
G Pctp phosphatidylcholine transfer protein acts_upstream_of_or_within ISO MGI:2673156 (MGI:3603484|PMID:15845870) RGD PMID:15845870 MGI:3603484 NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867
JBrowse link
G Pip4p1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 involved_in ISO
ISS
(PMID:25035345)
GO_REF:0000024
RGD
UniProt
PMID:25035345 GO_REF:0000024 NCBI chr15:24,146,854...24,150,739
Ensembl chr15:24,146,856...24,150,702
JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:3614822 (MGI:5616959|PMID:25429154) RGD PMID:25429154 MGI:5616959 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Pon1 paraoxonase 1 acts_upstream_of_or_within ISO MGI:2148702 (MGI:1860864|PMID:9685159) RGD PMID:9685159 MGI:1860864 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Scap SREBF chaperone involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:1934968|PMID:11358865)
UniProt
RGD
PMID:11358865 GO_REF:0000024 MGI:1934968 NCBI chr 8:110,306,031...110,360,677
Ensembl chr 8:110,306,031...110,360,666
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 acts_upstream_of_or_within ISO (MGI:5320806|PMID:22383528) RGD PMID:22383528 MGI:5320806 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794
JBrowse link
G Soat1 sterol O-acyltransferase 1 acts_upstream_of_or_within
involved_in
TAS
ISO
ISS
IBA
IEA
(PMID:9756919)
(PMID:16647063), (PMID:8407899)
(MGI:3603484|PMID:15845870)
GO_REF:0000024
PMID:21873635
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:8407899 PMID:9756919 PMID:15845870 PMID:16647063 PMID:9555010 More... GO_REF:0000024 GO_REF:0000107 MGI:3603484, RGD:730254, RGD:13792537 NCBI chr13:68,552,274...68,597,529
Ensembl chr13:68,552,317...68,597,494
JBrowse link
G Soat2 sterol O-acyltransferase 2 acts_upstream_of_or_within
involved_in
IDA
ISO
IEA
IBA
(MGI:1206070|PMID:9756919)
GO_REF:0000107
PMID:21873635
(PMID:11294643), (PMID:16647063)
RGD
Ensembl
PMID:9756919 PMID:11294643 PMID:16647063 PMID:12217884 PMID:21873635 GO_REF:0000107 MGI:1206070, RGD:625687, RGD:13792537 NCBI chr 7:133,281,818...133,294,915
Ensembl chr 7:133,281,818...133,294,915
JBrowse link
G Sqle squalene epoxidase involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:9300786 PMID:21873635 RGD:1625701, RGD:13792537 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 IMP RGD PMID:18071061 RGD:1643359 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf1_v2 sterol regulatory element binding factor 1, variant 2 IMP RGD PMID:18071061 RGD:1643359
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Star steroidogenic acute regulatory protein involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 involved_in ISO (PMID:28992322) RGD PMID:28992322 NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19589875)
UniProt
RGD
PMID:19589875 GO_REF:0000024 NCBI chr 1:75,451,178...75,508,142 JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 involved_in ISO
ISS
(PMID:28575648)
GO_REF:0000024
RGD
UniProt
PMID:28575648 GO_REF:0000024 NCBI chr 1:96,200,155...96,261,295
Ensembl chr 1:96,200,156...96,261,295
JBrowse link
G Tnfsf4 TNF superfamily member 4 acts_upstream_of_or_within ISO (MGI:57200|PMID:3473481) RGD PMID:3473481 MGI:57200 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6407480|PMID:31391339)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:31391339 GO_REF:0000024 GO_REF:0000107 MGI:6407480 NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588
JBrowse link
G Vldlr very low density lipoprotein receptor involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
JBrowse link
cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07021955.1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041
G AABR07028137.1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G AABR07028157.1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G AABR07060293.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 4:67,330,588...67,331,346 JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 involved_in TAS PMID:10806397 UniProt PMID:10806397 RGD:2326086 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Apoa1 apolipoprotein A1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2180783 (MGI:2180727|PMID:8647961)
RGD PMID:8647961 PMID:21873635 MGI:2180727, RGD:13792537 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa4 apolipoprotein A4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoa5 apolipoprotein A5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Ces1d carboxylesterase 1D involved_in ISO (PMID:11015575) RGD PMID:11015575 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Cftr CF transmembrane conductance regulator involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856709 (MGI:3709533|PMID:17085523)
Ensembl
RGD
PMID:17085523 GO_REF:0000107 MGI:3709533 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:11519011)
MGI:3027024 (MGI:2686848|PMID:14684813), (MGI:3624168|PMID:16321981), (MGI:3769949|PMID:16513830)
UniProt
RGD
PMID:11519011 PMID:14684813 PMID:16321981 PMID:16513830 GO_REF:0000024 MGI:2686848 MGI:3624168 MGI:3769949 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase involved_in TAS
IBA
IEA
ISO
IMP
IC
IDA
PMID:21873635
GO_REF:0000041
(PMID:9465114)
UniProt
RGD
PMID:9465114 PMID:12031495 PMID:21873635 PMID:9831636 PMID:10666310 More... GO_REF:0000041, RGD:625561, RGD:13792537, RGD:2316918, RGD:2316916, RGD:632010 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Ebp EBP, cholestenol delta-isomerase involved_in IDA
ISO
IBA
IEA
TAS
(PMID:9894009)
PMID:21873635
GO_REF:0000041
RGD
UniProt
PMID:9894009 PMID:11171067 PMID:21873635 PMID:11171067 GO_REF:0000041, RGD:628445, RGD:13792537, RGD:628445 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 involved_in TAS
IBA
IMP
PMID:21873635 RGD
GO_Central
PMID:1400448 PMID:21873635 PMID:16440058 RGD:728402, RGD:13792537, RGD:1626611 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fdps farnesyl diphosphate synthase TAS RGD PMID:1321149 RGD:728501 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase involved_in ISO (PMID:12027950) RGD PMID:12027950 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase involved_in
acts_upstream_of_or_within
ISO (PMID:23063590)
(MGI:2180727|PMID:8647961), (MGI:3603484|PMID:15845870), (MGI:70238|PMID:7798939)
RGD PMID:7798939 PMID:8647961 PMID:15845870 PMID:23063590 MGI:2180727 MGI:3603484 MGI:70238 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 involved_in
acts_upstream_of_or_within
ISO
IBA
ISS
IEA
(PMID:12829805)
(MGI:2673751|PMID:12829805)
PMID:21873635
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:12829805 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:2673751, RGD:13792537 NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 involved_in TAS
IEA
GO_REF:0000043 UniProt
RGD
PMID:9228075 GO_REF:0000043, RGD:729078 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Insig1 insulin induced gene 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1920249 (MGI:3689278|PMID:16955138)
(PMID:32322062)
RGD PMID:16955138 PMID:32322062 PMID:21873635 MGI:3689278, RGD:13792537 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insig2 insulin induced gene 2 involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
GO_REF:0000024
MGI:1916289 (MGI:3689278|PMID:16955138)
PMID:21873635
(PMID:32322062)
UniProt
RGD
PMID:16955138 PMID:32322062 PMID:21873635 GO_REF:0000024 MGI:3689278, RGD:13792537 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
JBrowse link
G Lbr lamin B receptor involved_in ISO
IEA
ISS
(PMID:16784888), (PMID:27336722)
(MGI:3822946|PMID:18785926), (MGI:5308142|PMID:22140257)
GO_REF:0000041
GO_REF:0000024
RGD
UniProt
PMID:16784888 PMID:18785926 PMID:22140257 PMID:27336722 GO_REF:0000024 GO_REF:0000041 MGI:3822946 MGI:5308142 NCBI chr13:93,539,360...93,564,065 JBrowse link
G LOC102551575 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,504,294...61,507,015
Ensembl chr17:61,504,535...61,507,015
JBrowse link
G LOC103694120 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,420,357...61,423,924 JBrowse link
G LOC291276 similar to isopentenyl diphosphate delta-isomerase type 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,549,335...61,553,178 JBrowse link
G Lss lanosterol synthase involved_in IMP
IDA
IBA
ISO
IEA
PMID:7568116
PMID:21873635
(PMID:17186944)
GO_REF:0000107
RGD
Ensembl
PMID:17186944 PMID:16440058 PMID:7568116 PMID:21873635 PMID:1429550 GO_REF:0000107, RGD:1626611, RGD:728996, RGD:13792537, RGD:2316919 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
JBrowse link
G Msmo1 methylsterol monooxygenase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
JBrowse link
G Mvd mevalonate diphosphate decarboxylase involved_in NAS
IEA
GO_REF:0000041 UniProt
RGD
PMID:11767099 GO_REF:0000041, RGD:729305 NCBI chr19:50,496,366...50,506,389
Ensembl chr19:50,496,367...50,507,971
JBrowse link
G Mvk mevalonate kinase involved_in TAS
IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:1377680)
Ensembl
RGD
PMID:1377680 PMID:2158094 PMID:21873635 GO_REF:0000107, RGD:728935, RGD:13792537 NCBI chr12:42,141,391...42,158,858
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 involved_in ISO (PMID:17140581) RGD PMID:17140581 NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142
JBrowse link
G Pmvk phosphomevalonate kinase involved_in IBA
NAS
ISO
PMID:21873635
PMID:10191291
(PMID:8663599)
RGD PMID:8663599 PMID:21873635 PMID:10191291 RGD:13792537, RGD:8553625 NCBI chr 2:174,876,586...174,886,365
Ensembl chr 2:174,876,657...174,886,364
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G RGD1564347 similar to isopentenyl diphosphate delta-isomerase type 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,372,853...61,386,459 JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 involved_in IEA
ISO
IDA
GO_REF:0000041
(MGI:3822946|PMID:18785926)
PMID:16784888
(PMID:16784888)
UniProt
RGD
PMID:16784888 PMID:18785926 PMID:16784888 GO_REF:0000041 MGI:3822946, RGD:13825441 NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270
JBrowse link
cholesterol biosynthetic process via 24,25-dihydrolanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp51 cytochrome P450, family 51 IDA RGD PMID:7581240 RGD:2316902 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
cholesterol biosynthetic process via desmosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhcr24 24-dehydrocholesterol reductase involved_in ISO (PMID:11519011) RGD PMID:11519011 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
cholesterol biosynthetic process via lathosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sc5d sterol-C5-desaturase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:7961720 PMID:21873635 RGD:2316911, RGD:13792537 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273
JBrowse link
cholesterol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1d1 aldo-keto reductase family 1, member D1 involved_in ISO
IEA
(PMID:7508385)
GO_REF:0000107
RGD
Ensembl
PMID:7508385 GO_REF:0000107 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
JBrowse link
G Apoe apolipoprotein E involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1314982|PMID:9826706)
RGD PMID:9826706 PMID:21873635 MGI:1314982, RGD:13792537 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Cel carboxyl ester lipase involved_in ISO
IEA
(PMID:12031288)
GO_REF:0000107
RGD
Ensembl
PMID:12031288 GO_REF:0000107 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
GO_REF:0000041
(PMID:9660774)
UniProt
Ensembl
RGD
PMID:9660774 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 acts_upstream_of_or_within ISO (MGI:1859119|PMID:10748047) RGD PMID:10748047 MGI:1859119 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775
JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 involved_in IBA
ISO
PMID:21873635
(MGI:1339884|PMID:10377398), (MGI:6393037|PMID:20193040)
(PMID:14640697), (PMID:18621681), (PMID:25017465)
RGD PMID:10377398 PMID:14640697 PMID:18621681 PMID:20193040 PMID:25017465 More... MGI:1339884 MGI:6393037, RGD:13792537 NCBI chr 6:127,243,315...127,274,765
Ensembl chr 6:127,243,315...127,274,760
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in
acts_upstream_of_or_within
IDA
ISO
IEA
PMID:1694852
(MGI:1933035|PMID:11279518), (MGI:3603484|PMID:15845870)
GO_REF:0000041
RGD
UniProt
PMID:11279518 PMID:15845870 PMID:1694852 GO_REF:0000041 MGI:1933035 MGI:3603484, RGD:70534 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 IDA RGD PMID:16081591 RGD:1599972 NCBI chr 1:182,411,836...182,415,447
Ensembl chr 1:182,412,151...182,415,442
JBrowse link
G Mt3 metallothionein 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:4881636|PMID:20544854)
UniProt
RGD
PMID:20544854 GO_REF:0000024 MGI:4881636 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
JBrowse link
G Scarb1 scavenger receptor class B, member 1 acts_upstream_of_or_within ISO MGI:1928989 (MGI:1934548|PMID:11278646), (MGI:3690692|PMID:10559220) RGD PMID:10559220 PMID:11278646 MGI:1934548 MGI:3690692 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IDA
ISO
IEA
(PMID:1917954)
GO_REF:0000107
RGD
Ensembl
PMID:1917954 PMID:9225228 GO_REF:0000107, RGD:10059686 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671
JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (MGI:5490819|PMID:17202134) RGD PMID:17202134 MGI:5490819 NCBI chr17:61,331,669...61,334,285
Ensembl chr17:61,331,669...61,334,285
JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:15473258)
UniProt
RGD
PMID:15473258 GO_REF:0000024 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3768186|PMID:17916878) RGD PMID:17916878 MGI:3768186 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in IDA PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:18637708 RGD:2316295 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19229075)
UniProt
RGD
PMID:19229075 GO_REF:0000024 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Por cytochrome p450 oxidoreductase IMP RGD PMID:19264869 RGD:2316785 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Scap SREBF chaperone involved_in ISO (PMID:32322062) RGD PMID:32322062 NCBI chr 8:110,306,031...110,360,677
Ensembl chr 8:110,306,031...110,360,666
JBrowse link
G Scp2 sterol carrier protein 2 IDA RGD PMID:2554812 RGD:9850260 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 IDA RGD PMID:11226224 RGD:727312 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:32322062)
(MGI:3623165|PMID:9062341), (MGI:83216|PMID:8833906)
MGI:2177958|MGI:2177959 (MGI:1098057|PMID:9329978), (MGI:3603730|PMID:16046411)
GO_REF:0000024
RGD
UniProt
PMID:8833906 PMID:9062341 PMID:9329978 PMID:16046411 PMID:32322062 GO_REF:0000024 MGI:1098057 MGI:3603730 MGI:3623165 MGI:83216 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:32322062)
UniProt
RGD
PMID:32322062 GO_REF:0000024 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
positive regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D involved_in ISO (PMID:16971496) RGD PMID:16971496 NCBI chr19:13,873,490...13,912,035 JBrowse link
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 NOT|involved_in ISO (PMID:21810484) RGD PMID:21810484 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Apob apolipoprotein B acts_upstream_of_or_within ISO MGI:2183298 (MGI:3652707|PMID:16455790) RGD PMID:16455790 MGI:3652707 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Cyp51 cytochrome P450, family 51 TAS RGD PMID:7665087 RGD:1298863 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase IDA RGD PMID:10329655 RGD:632010 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:6278041|PMID:29395055)
UniProt
RGD
PMID:29395055 GO_REF:0000024 MGI:6278041 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880
JBrowse link
G Mvk mevalonate kinase NAS RGD PMID:2158094 RGD:728935 NCBI chr12:42,141,391...42,158,858
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Pex2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO MGI:2180128 (MGI:3027293|PMID:14673138) RGD PMID:14673138 MGI:3027293 NCBI chr 2:96,050,380...96,072,928
Ensembl chr 2:96,045,958...96,073,404
JBrowse link
G Scap SREBF chaperone acts_upstream_of_or_within ISO MGI:2148743|MGI:2180899 (MGI:3770209|PMID:16054043) RGD PMID:16054043 MGI:3770209 NCBI chr 8:110,306,031...110,360,677
Ensembl chr 8:110,306,031...110,360,666
JBrowse link
regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase, long chain involved_in ISO (MGI:3526480|PMID:15639194) RGD PMID:15639194 MGI:3526480 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain involved_in IEA
ISO
GO_REF:0000107
(MGI:3526480|PMID:15639194)
Ensembl
RGD
PMID:15639194 GO_REF:0000107 MGI:3526480 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
JBrowse link
G Apoe apolipoprotein E involved_in ISO UniProtKB:P35951 (PMID:24412220) RGD PMID:24412220 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator involved_in
acts_upstream_of_or_within
ISO (PMID:20663892)
(MGI:4849624|PMID:20663892)
RGD PMID:20663892 MGI:4849624 NCBI chr19:52,692,337...52,704,156
Ensembl chr19:52,692,337...52,704,156
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 IMP RGD PMID:17526931 RGD:10400884 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:24369117) RGD PMID:24369117 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131
JBrowse link
G Ephx2 epoxide hydrolase 2 involved_in ISO
IEA
(PMID:18974052)
(MGI:3829349|PMID:18974052)
GO_REF:0000107
RGD
Ensembl
PMID:18974052 GO_REF:0000107 MGI:3829349 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5648738|PMID:26049045)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:26049045 GO_REF:0000024 GO_REF:0000107 MGI:5648738 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
JBrowse link
G Gnb3 G protein subunit beta 3 involved_in ISO UniProtKB:Q61011 (PMID:29206867) RGD PMID:29206867 NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173
JBrowse link
G Ldlr low density lipoprotein receptor involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P02649 (MGI:5575733|PMID:24412220)
Ensembl
RGD
PMID:24412220 GO_REF:0000107 MGI:5575733 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lmf1 lipase maturation factor 1 acts_upstream_of_or_within ISO MGI:1856820 (MGI:55554|PMID:6857276) RGD PMID:6857276 MGI:55554 NCBI chr10:14,597,726...14,684,071
Ensembl chr10:14,597,594...14,684,119
JBrowse link
G Por cytochrome p450 oxidoreductase IMP RGD PMID:19264869 RGD:2316785 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Serpina12 serpin family A member 12 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5568548 (MGI:5563627|PMID:22837305)
Ensembl
RGD
PMID:22837305 GO_REF:0000107 MGI:5563627 NCBI chr 6:122,952,552...122,967,271
Ensembl chr 6:122,952,552...122,967,271
JBrowse link
G Thrb thyroid hormone receptor beta IMP RGD PMID:17878314 RGD:2315101 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Ttc39b tetratricopeptide repeat domain 39B involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:5800596|PMID:27383786)
PMID:21873635
UniProt
RGD
PMID:27383786 PMID:21873635 GO_REF:0000024 MGI:5800596, RGD:13792537 NCBI chr 5:97,603,329...97,708,103
Ensembl chr 5:97,609,392...97,736,270
JBrowse link
G Ttc39d tetratricopeptide repeat domain 39D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:14,802,753...14,811,516
Ensembl chr 6:14,786,089...14,811,978
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19504
    metabolic process 11814
      small molecule metabolic process 1794
        alcohol metabolic process 365
          secondary alcohol metabolic process 155
            cholesterol metabolic process 140
              cholesterol biosynthetic process + 59
              cholesterol catabolic process 10
              cholesterol ester hydrolysis involved in cholesterol transport 0
              negative regulation of cholesterol metabolic process + 5
              peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine 0
              positive regulation of cholesterol metabolic process + 11
              regulation of cholesterol metabolic process + 37
Path 2
Term Annotations click to browse term
  biological_process 19504
    metabolic process 11814
      primary metabolic process 10544
        lipid metabolic process 1365
          steroid metabolic process 334
            sterol metabolic process 148
              cholesterol metabolic process 140
                cholesterol biosynthetic process + 59
                cholesterol catabolic process 10
                cholesterol ester hydrolysis involved in cholesterol transport 0
                negative regulation of cholesterol metabolic process + 5
                peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine 0
                positive regulation of cholesterol metabolic process + 11
                regulation of cholesterol metabolic process + 37
paths to the root