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ONTOLOGY REPORT - ANNOTATIONS

Term:O-methyltransferase activity
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Accession:GO:0008171 term browser browse the term
Definition:Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
Synonyms:xref: reactome:R-HSA-5578717 "BCDIN3D dimethylates 5' phosphate of pre-miR-145";   reactome:R-HSA-5629203 "HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 4xMeR-PIWIL1:piRNA:TDRD6:TDRKH";   reactome:R-HSA-5629218 "HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 6xMeR-PIWIL2:piRNA:TDRD1:TDRD12:DDX4:ASZ:MOV10L1";   reactome:R-HSA-5629237 "HENMT1 methylates 2' hydroxyl at 3' end of piRNA in MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH";   reactome:R-HSA-6790907 "Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides"


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O-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcdin3d BCDIN3 domain containing RNA methyltransferase enables ISO
IBA		 (PMID:23063121)
GO_REF:0000033		 RGD
GO_Central		 PMID:23063121 GO_REF:0000033 NCBI chr 7:132,484,404...132,488,998
Ensembl chr 7:130,605,541...130,610,115 		JBrowse link
G Comtd1 catechol-O-methyltransferase domain containing 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:2,509,121...2,512,232
Ensembl chr15:2,459,783...2,462,895 		JBrowse link
G Coq3 coenzyme Q3 methyltransferase enables ISO UniProtKB:P27680 (PMID:10777520) RGD PMID:10777520 NCBI chr 5:40,226,313...40,257,383
Ensembl chr 5:35,429,574...35,460,607 		JBrowse link
G Henmt1 HEN methyltransferase 1 enables ISS
ISO
IBA
IEA		 GO_REF:0000024
(PMID:17652135), (PMID:18029764)
GO_REF:0000033
GO_REF:0000002		 UniProt
RGD
GO_Central
InterPro		 PMID:17652135 PMID:18029764 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:199,258,107...199,291,739
Ensembl chr 2:196,586,797...196,599,738 		JBrowse link
G Henmt1 HEN methyltransferase 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 2:196,586,797...196,599,738 JBrowse link
G Mepce methylphosphate capping enzyme enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:24,548,596...24,553,315
Ensembl chr12:18,911,796...18,916,514 		JBrowse link
3-demethylubiquinol 3-O-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coq3 coenzyme Q3 methyltransferase enables ISO
IBA		 (PMID:10777520)
GO_REF:0000033		 RGD
GO_Central		 PMID:10777520 GO_REF:0000033 NCBI chr 5:40,226,313...40,257,383
Ensembl chr 5:35,429,574...35,460,607 		JBrowse link
acetylserotonin O-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asmt acetylserotonin O-methyltransferase enables IDA
ISO
IBA
IEA		 (PMID:20308563), (PMID:3941912)
GO_REF:0000033
GO_REF:0000003
(PMID:22775292)		 RGD
GO_Central
UniProt		 PMID:3941912 PMID:20308563 PMID:22775292 PMID:8930356 PMID:12198599 GO_REF:0000003 GO_REF:0000033, RGD:1299464, RGD:1359073 NCBI chr12:21,418,477...21,423,336
Ensembl chr12:16,304,719...16,309,568 		JBrowse link
catechol O-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase enables IDA
ISO
IBA
IEA		 (PMID:12188925), (PMID:17724020), (PMID:20374420), (PMID:20618449), (PMID:24509724), (PMID:27388330)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000104
(PMID:11559542), (PMID:15645182), (PMID:21846718)		 RGD
GO_Central
Ensembl
UniProt		 PMID:11559542 PMID:12188925 PMID:15645182 PMID:17724020 PMID:20374420 More... GO_REF:0000033 GO_REF:0000104 GO_REF:0000107, RGD:1359089 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing enables ISS
ISO
IBA		 GO_REF:0000024
(PMID:18794526)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:18794526 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:165,678,654...165,680,703
Ensembl chr 1:156,266,655...156,268,704 		JBrowse link
mRNA (nucleoside-2'-O-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmtr1 cap methyltransferase 1 enables ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000117
GO_REF:0000003
(PMID:20713356), (PMID:21310715)		 UniProt
GO_Central
RGD		 PMID:20713356 PMID:21310715 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000117 NCBI chr20:7,724,286...7,784,787
Ensembl chr20:7,709,713...7,766,302 		JBrowse link
G Cmtr2 cap methyltransferase 2 enables ISO
IBA		 (PMID:21310715)
GO_REF:0000033		 RGD
GO_Central		 PMID:21310715 GO_REF:0000033 NCBI chr19:55,100,135...55,106,966
Ensembl chr19:38,190,642...38,197,804 		JBrowse link
protein C-terminal carboxyl O-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lcmt1 leucine carboxyl methyltransferase 1 enables ISO (PMID:10600115) RGD PMID:10600115 NCBI chr 1:187,335,173...187,391,195
Ensembl chr 1:177,904,139...177,960,112 		JBrowse link
protein C-terminal leucine carboxyl O-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lcmt1 leucine carboxyl methyltransferase 1 enables IEA
IBA		 GO_REF:0000003
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000003 GO_REF:0000033 NCBI chr 1:187,335,173...187,391,195
Ensembl chr 1:177,904,139...177,960,112 		JBrowse link
protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Icmt isoprenylcysteine carboxyl methyltransferase enables IMP
ISO
IBA		 MGI:2680650 (PMID:10747846), (PMID:11121396)
(PMID:29051265), (PMID:9614111)
GO_REF:0000033		 RGD
GO_Central		 PMID:9614111 PMID:10747846 PMID:11121396 PMID:29051265 PMID:9192075 GO_REF:0000033, RGD:2289655 NCBI chr 5:168,084,487...168,097,519
Ensembl chr 5:162,804,368...162,811,128 		JBrowse link
protein carboxyl O-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Armt1 acidic residue methyltransferase 1 enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000104
(PMID:25732820)		 UniProt
RGD		 PMID:25732820 GO_REF:0000024 GO_REF:0000104 NCBI chr 1:43,299,916...43,323,675
Ensembl chr 1:40,894,550...40,918,302 		JBrowse link
protein-glutamate O-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Armt1 acidic residue methyltransferase 1 enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 1:43,299,916...43,323,675
Ensembl chr 1:40,894,550...40,918,302 		JBrowse link
protein-L-isoaspartate (D-aspartate) O-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 enables IDA
IBA
ISO
IEA		 GO_REF:0000033
(PMID:12023972)
(PMID:3167043)
GO_REF:0000003		 GO_Central
RGD
UniProt		 PMID:3167043 PMID:12023972 PMID:8263531 GO_REF:0000003 GO_REF:0000033, RGD:729481 NCBI chr 1:3,932,161...3,980,751
Ensembl chr 1:2,111,763...2,159,201 		JBrowse link
G Pcmtd1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:17,071,629...17,143,803
Ensembl chr 5:12,284,711...12,354,899 		JBrowse link
G Pcmtd2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:189,337,758...189,360,525
Ensembl chr 3:168,960,305...168,979,497 		JBrowse link
RNA 2'-O-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ftsj3 FtsJ RNA 2'-O-methyltransferase 3 enables ISO
ISS		 (PMID:30626973)
GO_REF:0000024		 RGD
UniProt		 PMID:30626973 GO_REF:0000024 NCBI chr10:91,680,735...91,687,475
Ensembl chr10:91,180,696...91,187,397 		JBrowse link
RNA 5'-gamma-phosphate methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mepce methylphosphate capping enzyme enables ISO (PMID:19906723), (PMID:28431135), (PMID:30559425) RGD PMID:19906723 PMID:28431135 PMID:30559425 NCBI chr12:24,548,596...24,553,315
Ensembl chr12:18,911,796...18,916,514 		JBrowse link
rRNA (guanosine-2'-O-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mrm1 mitochondrial rRNA methyltransferase 1 enables ISO (PMID:25074936), (PMID:35177605) RGD PMID:25074936 PMID:35177605 NCBI chr10:70,187,842...70,194,785
Ensembl chr10:69,690,421...69,696,709 		JBrowse link
G Mrm3 mitochondrial rRNA methyltransferase 3 enables ISO (PMID:24036117), (PMID:25074936), (PMID:35177605) RGD PMID:24036117 PMID:25074936 PMID:35177605 NCBI chr10:61,594,155...61,623,659
Ensembl chr10:61,095,952...61,102,630 		JBrowse link
rRNA (uridine-2'-O-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000063747 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 2:161,604,723...161,605,121 JBrowse link
G Ftsj3 FtsJ RNA 2'-O-methyltransferase 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:91,680,735...91,687,475
Ensembl chr10:91,180,696...91,187,397 		JBrowse link
G Mrm2 mitochondrial rRNA methyltransferase 2 enables ISO
IBA		 (PMID:25074936), (PMID:35177605)
GO_REF:0000033		 RGD
GO_Central		 PMID:25074936 PMID:35177605 GO_REF:0000033 NCBI chr12:19,423,448...19,428,662
Ensembl chr12:14,251,941...14,314,118 		JBrowse link
small RNA 2'-O-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcdin3d BCDIN3 domain containing RNA methyltransferase enables ISS
ISO		 GO_REF:0000024
(PMID:23063121)		 UniProt
RGD		 PMID:23063121 GO_REF:0000024 NCBI chr 7:132,484,404...132,488,998
Ensembl chr 7:130,605,541...130,610,115 		JBrowse link
G Henmt1 HEN methyltransferase 1 enables ISO
IEA		 (PMID:11283698)
GO_REF:0000107		 RGD
Ensembl		 PMID:11283698 GO_REF:0000107 NCBI chr 2:199,258,107...199,291,739
Ensembl chr 2:196,586,797...196,599,738 		JBrowse link
tRNA 2'-O-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ftsj1 FtsJ RNA 2'-O-methyltransferase 1 enables ISO (PMID:25404562), (PMID:26310293) RGD PMID:25404562 PMID:26310293 NCBI chr  X:16,915,087...16,929,426
Ensembl chr  X:14,244,050...14,252,030 		JBrowse link
G Trmt13 tRNA methyltransferase 13 homolog enables IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 2:207,217,399...207,232,467
Ensembl chr 2:204,533,632...204,546,843 		JBrowse link
U6 snRNA 2'-O-ribose methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbl fibrillarin enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 1:92,597,407...92,606,507
Ensembl chr 1:83,469,832...83,478,932 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21091
    catalytic activity 6174
      transferase activity 2443
        transferase activity, transferring one-carbon groups 214
          methyltransferase activity 203
            O-methyltransferase activity 25
              (iso)eugenol O-methyltransferase activity 0
              2-phytyl-1,4-naphthoquinone methyltransferase activity 0
              2-polyprenyl-6-hydroxyphenol O-methyltransferase activity 0
              3-demethylubiquinol 3-O-methyltransferase activity 1
              3-demethylubiquinone 3-O-methyltransferase activity 0
              RNA 2'-O-methyltransferase activity + 10
              RNA 5'-gamma-phosphate methyltransferase activity 1
              S-adenosyl-L-methionine:benzoic acid carboxyl methyl transferase activity 0
              acetylserotonin O-methyltransferase activity 1
              caffeate O-methyltransferase activity 0
              caffeoyl-CoA O-methyltransferase activity 0
              carboxyl-O-methyltransferase activity + 6
              catechol O-methyltransferase activity 2
              demethylsterigmatocystin 6-O-methyltransferase activity 0
              farnesoic acid O-methyltransferase activity 0
              flavone 3'-O-methyltransferase activity 0
              isoflavone 7-O-methyltransferase activity 0
              isoliquiritigenin 2'-O-methyltransferase activity 0
              kaempferol 4'-O-methyltransferase activity 0
              laricitrin 5'-O-methyltransferase activity 0
              mRNA (nucleoside-2'-O-)-methyltransferase activity 2
              magnesium protoporphyrin IX methyltransferase activity 0
              myricetin 3'-O-methyltransferase activity 0
              sterigmatocystin 7-O-methyltransferase activity 0
              tocopherol C-methyltransferase activity 0
              tricaffeoyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity 0
              trihydroxyferuloyl spermidine O-methyltransferase activity 0
              trihydroxyferuloyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity 0
              vitexin 2''-O-rhamnoside 7-O-methyltransferase activity 0
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