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ONTOLOGY REPORT - ANNOTATIONS


Term:drug binding
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Accession:GO:0008144 term browser browse the term
Definition:Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.


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drug binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chka choline kinase alpha enables ISS
ISO
GO_REF:0000024
(PMID:19915674)
UniProt
RGD
PMID:19915674 GO_REF:0000024 NCBI chr 1:219,076,618...219,126,221
Ensembl chr 1:219,077,771...219,126,220
JBrowse link
G Dck deoxycytidine kinase enables ISO
IEA
(PMID:12808445)
GO_REF:0000107
RGD
Ensembl
PMID:12808445 GO_REF:0000107 NCBI chr14:20,935,442...20,952,939
Ensembl chr14:20,935,369...20,953,095
JBrowse link
G Dhfr dihydrofolate reductase enables ISS
ISO
GO_REF:0000024
(PMID:12096917), (PMID:15039552)
UniProt
RGD
PMID:12096917 PMID:15039552 GO_REF:0000024 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Fscn1 fascin actin-bundling protein 1 enables ISO
IEA
(PMID:20393565)
(MGI:4888112|PMID:20393565)
GO_REF:0000107
RGD
Ensembl
PMID:20393565 GO_REF:0000107 MGI:4888112 NCBI chr12:13,655,459...13,668,595
Ensembl chr12:13,656,554...13,668,515
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 enables ISS
ISO
GO_REF:0000024
(PMID:12578355)
UniProt
RGD
PMID:12578355 GO_REF:0000024 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha enables ISO
ISS
(PMID:12955147)
GO_REF:0000024
RGD
UniProt
PMID:12955147 GO_REF:0000024 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta enables ISO (PMID:10198642) RGD PMID:10198642 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 enables ISO (PMID:20610558) RGD PMID:20610558 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
cocaine binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a4 solute carrier family 6 member 4 IMP RGD PMID:15994310 RGD:1580635 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
cyclosporin A binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07004183.1 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 1:129,227,595...129,228,068 JBrowse link
G AABR07056556.1 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 7:29,909,120...29,909,614 JBrowse link
G Cwc27 CWC27 spliceosome associated cyclophilin NOT|enables ISO (PMID:20676357) RGD PMID:20676357 NCBI chr 2:34,716,420...34,923,060
Ensembl chr 2:34,719,344...34,923,024
JBrowse link
G LOC100911252 peptidyl-prolyl cis-trans isomerase A-like enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:40,004,617...40,005,358
Ensembl chr 4:40,004,654...40,005,148
JBrowse link
G Nktr natural killer cell triggering receptor enables ISO
IBA
(PMID:20676357)
PMID:21873635
RGD PMID:20676357, PMID:21873635 RGD:13792537 NCBI chr 8:130,357,464...130,395,425
Ensembl chr 8:130,366,775...130,393,178
JBrowse link
G Ppia peptidylprolyl isomerase A enables IDA
IBA
ISO
PMID:21873635
(PMID:12218175), (PMID:12357034), (PMID:2001362), (PMID:20676357)
RGD PMID:2001362 PMID:12218175 PMID:12357034 PMID:20676357, PMID:19832699, PMID:21873635 RGD:7247324, RGD:13792537 NCBI chr14:86,673,775...86,677,443
Ensembl chr14:86,673,775...86,677,443
JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:22,706,906...22,707,648
Ensembl chr14:22,706,901...22,707,668
JBrowse link
G Ppial4g peptidylprolyl isomerase A like 4G enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:81,576,690...81,577,379
Ensembl chr15:81,576,888...81,577,379
JBrowse link
G Ppib peptidylprolyl isomerase B enables ISO
IBA
ISS
(PMID:20676357)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:20676357, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:71,719,681...71,725,538
Ensembl chr 8:71,719,563...71,725,562
JBrowse link
G Ppic peptidylprolyl isomerase C enables TAS
ISO
IBA
(PMID:1652374), (PMID:20676357)
PMID:21873635
RGD PMID:1652374 PMID:20676357, PMID:15647740, PMID:21873635 RGD:1334475, RGD:13792537 NCBI chr18:48,372,039...48,384,645
Ensembl chr18:48,372,041...48,384,645
JBrowse link
G Ppid peptidylprolyl isomerase D enables IDA
ISO
IBA
(PMID:20676357)
PMID:21873635
RGD PMID:20676357, PMID:19832699, PMID:21873635 RGD:7247324, RGD:13792537 NCBI chr 2:178,354,830...178,366,843
Ensembl chr 2:178,354,890...178,366,685
JBrowse link
G Ppidl1 peptidylprolyl isomerase D-like 1 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:121,456,762...121,458,035
Ensembl chr 9:121,456,623...121,457,951
JBrowse link
G Ppie peptidylprolyl isomerase E enables IBA
ISO
PMID:21873635
(PMID:20676357)
RGD PMID:20676357, PMID:21873635 RGD:13792537 NCBI chr 5:140,822,141...140,835,244
Ensembl chr 5:140,822,141...140,834,959
JBrowse link
G Ppif peptidylprolyl isomerase F enables IDA
ISO
IBA
(PMID:20676357)
PMID:21873635
RGD PMID:20676357, PMID:1599421, PMID:21873635 RGD:729430, RGD:13792537 NCBI chr16:1,979,191...1,985,912
Ensembl chr16:1,979,191...1,985,908
JBrowse link
G Ppig peptidylprolyl isomerase G enables IBA
IEA
ISO
ISS
PMID:21873635
GO_REF:0000107
(PMID:20676357)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:20676357, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 3:55,959,756...55,990,040
Ensembl chr 3:55,960,067...55,988,968
JBrowse link
G Ppih peptidylprolyl isomerase H enables IBA
ISO
PMID:21873635
(PMID:20676357)
RGD PMID:20676357, PMID:21873635 RGD:13792537 NCBI chr 5:138,343,934...138,361,743
Ensembl chr 5:138,352,916...138,361,702
JBrowse link
G Ppil1 peptidylprolyl isomerase like 1 enables ISO (PMID:20676357) RGD PMID:20676357 NCBI chr20:6,515,638...6,864,571
Ensembl chr20:6,515,638...6,864,571
JBrowse link
G Ppil2 peptidylprolyl isomerase like 2 NOT|enables ISO (PMID:20676357) RGD PMID:20676357 NCBI chr11:88,147,342...88,169,968
Ensembl chr11:88,147,377...88,169,968
JBrowse link
G Ppil6 peptidylprolyl isomerase like 6 NOT|enables ISO (PMID:20676357) RGD PMID:20676357 NCBI chr20:46,215,317...46,244,522
Ensembl chr20:46,215,379...46,243,707
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha enables ISO (PMID:12218175), (PMID:12357034) RGD PMID:12218175 PMID:12357034 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha enables ISO (PMID:12218175), (PMID:12357034) RGD PMID:12218175 PMID:12357034 NCBI chr14:100,311,224...100,360,879
Ensembl chr14:100,311,173...100,360,879
JBrowse link
G Ppwd1 peptidylprolyl isomerase domain and WD repeat containing 1 enables ISO (PMID:20676357) RGD PMID:20676357 NCBI chr 2:34,288,853...34,313,094
Ensembl chr 2:34,290,199...34,313,094
JBrowse link
G Ranbp2 RAN binding protein 2 NOT|enables ISO (PMID:20676357) RGD PMID:20676357 NCBI chr20:28,027,054...28,076,664
NCBI chr20:28,365,538...28,375,676
Ensembl chr20:28,027,054...28,076,664
Ensembl chr20:28,027,054...28,076,664
JBrowse link
diazepam binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 IDA RGD PMID:2166916 RGD:61594 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665
JBrowse link
G Htt huntingtin enables ISO MGI:2177743 (MGI:1333301|PMID:10082833) RGD PMID:10082833 MGI:1333301 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
enterobactin binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin enables IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:6234017)
Ensembl
UniProt
RGD
PMID:6234017 GO_REF:0000024 GO_REF:0000107 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Lcn2 lipocalin 2 enables ISS
ISO
GO_REF:0000024
(PMID:27780864)
UniProt
RGD
PMID:27780864 GO_REF:0000024 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
FK506 binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fkbp10 FKBP prolyl isomerase 10 enables ISO (MGI:77542|PMID:7493967) RGD PMID:7493967 MGI:77542 NCBI chr10:88,326,337...88,338,199
Ensembl chr10:88,326,080...88,338,207
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A enables IDA
ISO
(PMID:7592869)
(MGI:59984|PMID:1722474)
RGD PMID:1722474 PMID:7592869, PMID:9013543 MGI:59984, RGD:61587 NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B enables IDA
ISO
(MGI:3028710|PMID:14592808)
(PMID:7592869)
RGD PMID:7592869 PMID:14592808, PMID:9013543 MGI:3028710, RGD:61587 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:161,748,993...161,757,447
Ensembl chr 4:161,748,993...161,757,447
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
methotrexate binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhfr dihydrofolate reductase enables ISO (PMID:2303423) RGD PMID:2303423 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Folr1 folate receptor alpha enables ISO (PMID:19116913) RGD PMID:19116913 NCBI chr 1:166,934,457...166,945,864
Ensembl chr 1:166,934,460...166,943,592
JBrowse link
G Folr2 folate receptor beta enables ISO (PMID:19116913) RGD PMID:19116913 NCBI chr 1:166,915,045...166,933,377
Ensembl chr 1:166,915,045...166,919,302
JBrowse link
thienylcyclohexylpiperidine binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cep104 centrosomal protein 104 IMP RGD PMID:7488117 RGD:1299480 NCBI chr 5:171,262,278...171,294,560
Ensembl chr 5:171,262,278...171,294,559
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20076
    binding 17050
      drug binding 44
        N-1-naphthylphthalamic acid binding 0
        cocaine binding 1
        cyclosporin A binding 23
        diazepam binding 2
        macrolide binding + 7
        methotrexate binding 3
        penicillin binding 0
        phenylalkylamine binding 0
        thienylcyclohexylpiperidine binding 1
paths to the root