Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:NADH dehydrogenase (ubiquinone) activity
go back to main search page
Accession:GO:0008137 term browser browse the term
Definition:Catalysis of the reaction: NADH + ubiquinone + 5 H+(in) = NAD+ + ubiquinol + 4 H+(out).
Synonyms:exact_synonym: ubiquinone reductase activity
 narrow_synonym: mitochondrial electron transport complex 1 activity
 related_synonym: DPNH-coenzyme Q reductase activity;   DPNH-ubiquinone reductase activity;   NADH coenzyme Q1 reductase activity;   NADH-CoQ oxidoreductase activity;   NADH-CoQ reductase activity;   NADH-Q6 oxidoreductase activity;   NADH-coenzyme Q oxidoreductase activity;   NADH-coenzyme Q reductase activity;   NADH-ubiquinone oxidoreductase activity;   NADH-ubiquinone reductase activity;   NADH-ubiquinone-1 reductase activity;   NADH:ubiquinone oxidoreductase complex activity;   coenzyme Q reductase activity;   complex 1 dehydrogenase activity;   complex I (NADH:Q1 oxidoreductase) activity;   complex I (electron transport chain) activity;   complex I (mitochondrial electron transport) activity;   dihydronicotinamide adenine dinucleotide-coenzyme Q reductase activity;   electron transfer complex I activity;   reduced nicotinamide adenine dinucleotide-coenzyme Q reductase activity;   type 1 dehydrogenase activity
 xref: EC:7.1.1.2;   MetaCyc:NADH-DEHYDROG-A-RXN;   RHEA:29091;   Reactome:R-HSA-163217 "Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2"

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
NADH dehydrogenase (ubiquinone) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ND1 NADH dehydrogenase subunit 1 enables IEA UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr MT:2,731...3,688 JBrowse link
G ND2 NADH dehydrogenase subunit 2 enables IEA TreeGrafter
RHEA
InterPro
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 NCBI chr MT:3,896...4,937 JBrowse link
G ND3 NADH dehydrogenase subunit 3 enables IEA TreeGrafter
Ensembl
UniProt
RHEA
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 NCBI chr MT:9,456...9,801 JBrowse link
G ND4 NADH dehydrogenase subunit 4 enables IEA UniProt
RHEA
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116 NCBI chr MT:10,165...11,542 JBrowse link
G ND4L NADH dehydrogenase subunit 4L enables IEA UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr MT:9,875...10,171 JBrowse link
G ND5 NADH dehydrogenase subunit 5 enables IEA Ensembl
InterPro
RHEA
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 NCBI chr MT:11,740...13,551 JBrowse link
G ND6 NADH dehydrogenase subunit 6 enables IEA InterPro
RHEA
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116 NCBI chr MT:13,548...14,078 JBrowse link
G Ndufa10 NADH:ubiquinone oxidoreductase subunit A10 enables ISO (PMID:24652937) MGI PMID:24652937 NCBI chrNW_004624847:4,371,264...4,412,334
Ensembl chrNW_004624847:4,370,570...4,412,393 		JBrowse link
G Ndufb7 NADH:ubiquinone oxidoreductase subunit B7 enables ISO (PMID:33502047) UniProt PMID:33502047 NCBI chrNW_004624901:1,668,619...1,672,275
Ensembl chrNW_004624901:1,668,618...1,672,296 		JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 contributes_to
enables		 ISO
IEA		 (PMID:15824269), (PMID:16478720), (PMID:16870178) UniProtKB
InterPro
UniProt		 PMID:15824269 PMID:16478720 PMID:16870178 GO_REF:0000002 GO_REF:0000003 NCBI chrNW_004624765:9,962,254...9,993,790
Ensembl chrNW_004624765:9,962,447...9,993,790 		JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 contributes_to
enables		 ISO
IEA		 PMID:30922174
(PMID:22036843), (PMID:30922174)		 UniProt
UniProt		 PMID:22036843 PMID:30922174 GO_REF:0000003 RGD:42722001 NCBI chrNW_004624794:172,543...189,031
Ensembl chrNW_004624794:172,707...185,073 		JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 contributes_to
enables		 ISO
IEA		 (PMID:30140060) UniProt
InterPro		 PMID:30140060 GO_REF:0000002 NCBI chrNW_004624767:1,238,953...1,243,945
Ensembl chrNW_004624767:1,237,261...1,244,031 		JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 enables
contributes_to		 ISO (PMID:18396137), (PMID:29501746)
(PMID:16478720)
(PMID:15038602), (PMID:16870178)
(PMID:10747996)
(PMID:26712463)		 MGI
UniProt
UniProtKB		 PMID:10747996 PMID:15038602 PMID:16478720 PMID:16870178 PMID:18396137 More... NCBI chrNW_004624759:5,630,522...5,733,928 JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 enables IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624828:7,298,290...7,307,113
Ensembl chrNW_004624828:7,294,327...7,306,814 		JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 contributes_to
enables		 ISO (PMID:9837812)
(PMID:22499348)		 UniProtKB
UniProt		 PMID:9837812 PMID:22499348 NCBI chrNW_004624767:18,822,763...18,826,907
Ensembl chrNW_004624767:18,822,526...18,827,057 		JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 enables IEA Ensembl
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 NCBI chrNW_004624767:18,934,063...18,938,652
Ensembl chrNW_004624767:18,929,879...18,939,242 		JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 enables
contributes_to		 ISO (PMID:28844695)
(PMID:12754703)
(PMID:29915388)		 UniProt PMID:12754703 PMID:28844695 PMID:29915388 NCBI chrNW_004624770:17,925,250...17,950,754 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18442
    electron transfer activity 57
      NADH dehydrogenase (ubiquinone) activity 17
Path 2
Term Annotations click to browse term
  molecular_function 18442
    transporter activity 1152
      transmembrane transporter activity 1051
        active transmembrane transporter activity 386
          primary active transmembrane transporter activity 134
            oxidoreduction-driven active transmembrane transporter activity 30
              NADH dehydrogenase (ubiquinone) activity 17
paths to the root