Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:NADH dehydrogenase (ubiquinone) activity
go back to main search page
Accession:GO:0008137 term browser browse the term
Definition:Catalysis of the reaction: NADH + ubiquinone + 5 H+(in) = NAD+ + ubiquinol + 4 H+(out).
Synonyms:exact_synonym: ubiquinone reductase activity
 narrow_synonym: mitochondrial electron transport complex 1 activity
 related_synonym: DPNH-coenzyme Q reductase activity;   DPNH-ubiquinone reductase activity;   NADH coenzyme Q1 reductase activity;   NADH-CoQ oxidoreductase activity;   NADH-CoQ reductase activity;   NADH-Q6 oxidoreductase activity;   NADH-coenzyme Q oxidoreductase activity;   NADH-coenzyme Q reductase activity;   NADH-ubiquinone oxidoreductase activity;   NADH-ubiquinone reductase activity;   NADH-ubiquinone-1 reductase activity;   NADH:ubiquinone oxidoreductase complex activity;   coenzyme Q reductase activity;   complex 1 dehydrogenase activity;   complex I (NADH:Q1 oxidoreductase) activity;   complex I (electron transport chain) activity;   complex I (mitochondrial electron transport) activity;   dihydronicotinamide adenine dinucleotide-coenzyme Q reductase activity;   electron transfer complex I activity;   reduced nicotinamide adenine dinucleotide-coenzyme Q reductase activity;   type 1 dehydrogenase activity
 xref: EC:7.1.1.2;   MetaCyc:NADH-DEHYDROG-A-RXN;   RHEA:29091;   Reactome:R-HSA-163217 "Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2"


show annotations for term's descendants           Sort by:
NADH dehydrogenase (ubiquinone) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ND1 NADH dehydrogenase subunit 1 enables IEA UniProt
Ensembl
RHEA		 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 NCBI chr MT:2,727...3,681 JBrowse link
G ND2 NADH dehydrogenase subunit 2 enables IEA
ISS		 UniProt
TreeGrafter
RHEA
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 NCBI chr MT:3,890...4,933
Ensembl chr MT:3,890...4,933 		JBrowse link
G ND3 NADH dehydrogenase subunit 3 enables IEA
ISS		 Ensembl
TreeGrafter
UniProt
InterPro
RHEA		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 NCBI chr MT:9,478...9,823
Ensembl chr MT:9,478...9,823 		JBrowse link
G ND4 NADH dehydrogenase subunit 4 enables IEA
ISS		 Ensembl
RHEA
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116 NCBI chr MT:10,179...11,556
Ensembl chr MT:10,179...11,556 		JBrowse link
G ND4L NADH dehydrogenase subunit 4L enables IEA
ISS		 RHEA
UniProt		 GO_REF:0000003 GO_REF:0000024 GO_REF:0000116 NCBI chr MT:9,889...10,185
Ensembl chr MT:9,889...10,185 		JBrowse link
G ND5 NADH dehydrogenase subunit 5 enables IEA
ISS		 UniProt
InterPro
Ensembl
RHEA		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr MT:11,756...13,567
Ensembl chr MT:11,756...13,567 		JBrowse link
G ND6 NADH dehydrogenase subunit 6 enables IEA
ISS		 UniProt
RHEA
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116 NCBI chr MT:13,568...14,092
Ensembl chr MT:13,568...14,092 		JBrowse link
G NDUFA10 NADH:ubiquinone oxidoreductase subunit A10 enables IEA Ensembl GO_REF:0000107 NCBI chr2B:127,204,900...127,269,478
Ensembl chr2B:246,022,168...246,087,658 		JBrowse link
G NDUFB7 NADH:ubiquinone oxidoreductase subunit B7 enables IEA Ensembl GO_REF:0000107 NCBI chr19:14,129,123...14,135,129
Ensembl chr19:14,972,882...14,978,730 		JBrowse link
G NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 contributes_to
enables		 ISO
IEA		 (PMID:15824269), (PMID:16478720), (PMID:16870178) UniProtKB
Ensembl
InterPro
UniProt		 PMID:15824269 PMID:16478720 PMID:16870178 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 NCBI chr2B:93,363,092...93,399,326
Ensembl chr2B:211,493,021...211,528,496 		JBrowse link
G NDUFS2 NADH:ubiquinone oxidoreductase core subunit S2 contributes_to
enables		 ISO
IEA		 (PMID:22036843), (PMID:30922174) UniProt
Ensembl
UniProt		 PMID:22036843 PMID:30922174 GO_REF:0000003 GO_REF:0000107 RGD:42722001 NCBI chr 1:136,609,822...136,626,851
Ensembl chr 1:140,526,690...140,538,705 		JBrowse link
G NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 contributes_to
enables		 ISO
IEA		 (PMID:30140060) UniProt
Ensembl
InterPro		 PMID:30140060 GO_REF:0000002 GO_REF:0000107 NCBI chr11:47,528,680...47,534,206
Ensembl chr11:48,078,332...48,083,863 		JBrowse link
G NDUFS4 NADH:ubiquinone oxidoreductase subunit S4 contributes_to
enables		 ISO
IEA		 (PMID:15038602), (PMID:16870178) UniProtKB
Ensembl		 PMID:15038602 PMID:16870178 GO_REF:0000107 NCBI chr 5:60,344,363...60,467,008
Ensembl chr 5:61,966,124...62,088,375 		JBrowse link
G NDUFS7 NADH:ubiquinone oxidoreductase core subunit S7 enables IEA UniProt
TreeGrafter
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 Ensembl chr19:1,357,389...1,369,539 JBrowse link
G NDUFS8 NADH:ubiquinone oxidoreductase core subunit S8 contributes_to
enables		 ISO
IEA		 (PMID:9837812) UniProtKB
Ensembl
UniProt		 PMID:9837812 GO_REF:0000003 GO_REF:0000107 NCBI chr11:63,112,536...63,118,600
Ensembl chr11:66,421,378...66,427,101 		JBrowse link
G NDUFV1 NADH:ubiquinone oxidoreductase core subunit V1 enables IEA InterPro
Ensembl
RHEA
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 NCBI chr11:62,964,970...62,970,605
Ensembl chr11:66,276,638...66,282,320 		JBrowse link
G NDUFV2 NADH:ubiquinone oxidoreductase core subunit V2 contributes_to
enables		 ISO (PMID:12754703)
(PMID:29915388)
(PMID:28844695)		 UniProt PMID:12754703 PMID:28844695 PMID:29915388 NCBI chr18:5,154,158...5,186,088
Ensembl chr18:7,433,167...7,464,884 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19165
    electron transfer activity 52
      NADH dehydrogenase (ubiquinone) activity 17
Path 2
Term Annotations click to browse term
  molecular_function 19165
    transporter activity 1163
      transmembrane transporter activity 1063
        active transmembrane transporter activity 386
          primary active transmembrane transporter activity 131
            oxidoreduction-driven active transmembrane transporter activity 31
              NADH dehydrogenase (ubiquinone) activity 17
paths to the root