prostaglandin-I synthase activity - Ontology Report

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Term:	prostaglandin-I synthase activity	go back to main search page
Accession:	GO:0008116	browse the term
Definition:	Catalysis of the reaction: prostaglandin H(2) = prostaglandin I(2).
Synonyms:	narrow_synonym:	cytochrome P450 CYP8A1
	related_synonym:	(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase activity; PGI(2) synthase activity; PGI(2) synthetase activity; PGI2 synthase activity; PGI2 synthetase activity; prostacyclin synthase activity; prostacycline synthetase activity; prostagladin I2 synthetase activity
	xref:	EC:5.3.99.4; KEGG_REACTION:R02267; MetaCyc:PROSTAGLANDIN-I-SYNTHASE-RXN; RHEA:23580; reactome:R-HSA-76496 "PTGIS, CYP8A1 isomerise PGH2 to PGI2"

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Genes (1)

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ptgis

prostaglandin I2 synthase

enables

GO_REF:0000003 GO_REF:0000024 GO_REF:0000118 RGD:727270 RGD:8693629

NCBI chrNW_004624790:5,850,647...5,885,754
Ensembl chrNW_004624790:5,850,810...5,886,014

Term paths to the root

Path 1
Term	Annotations
molecular_function	16334
catalytic activity	5071
isomerase activity	154
intramolecular oxidoreductase activity	46
prostaglandin-I synthase activity	1

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