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ONTOLOGY REPORT - ANNOTATIONS

Term:prostaglandin-I synthase activity
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Accession:GO:0008116 term browser browse the term
Definition:Catalysis of the reaction: prostaglandin H(2) = prostaglandin I(2).
Synonyms:narrow_synonym: cytochrome P450 CYP8A1
 related_synonym: (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase activity;   PGI(2) synthase activity;   PGI(2) synthetase activity;   PGI2 synthase activity;   PGI2 synthetase activity;   prostacyclin synthase activity;   prostacycline synthetase activity;   prostagladin I2 synthetase activity
 xref: EC:5.3.99.4;   KEGG_REACTION:R02267;   MetaCyc:PROSTAGLANDIN-I-SYNTHASE-RXN;   RHEA:23580;   reactome:R-HSA-76496 "PTGIS, CYP8A1 isomerise PGH2 to PGI2"


show annotations for term's descendants           Sort by:
prostaglandin-I synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07054614.1 enables IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Ptgis prostaglandin I2 synthase enables IMP
IDA
ISO
IEA
IBA		 (PMID:15115769), (PMID:20122998), (PMID:21296955)
GO_REF:0000003
GO_REF:0000107
GO_REF:0000033		 RGD
UniProt
Ensembl
GO_Central		 PMID:15115769 PMID:20122998 PMID:21296955 PMID:10359560 PMID:16094316 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107, RGD:727270, RGD:8693629 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
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Term Annotations click to browse term
  molecular_function 20733
    catalytic activity 6109
      isomerase activity 212
        intramolecular oxidoreductase activity 71
          prostaglandin-I synthase activity 2
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