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ONTOLOGY REPORT - ANNOTATIONS

Term:nicotinamide N-methyltransferase activity
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Accession:GO:0008112 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinamide = 1-methylnicotinamide + S-adenosyl-L-homocysteine.
Synonyms:related_synonym: S-adenosyl-L-methionine:nicotinamide N-methyltransferase activity;   nicotinamide methyltransferase activity
 xref: EC:2.1.1.1;   KEGG_REACTION:R01269;   MetaCyc:NICOTINAMIDE-N-METHYLTRANSFERASE-RXN;   RHEA:23884;   reactome:R-HSA-5359451 "NNMT transfers CH3 from SAM to NAM to form MNA"


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nicotinamide N-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nnmt nicotinamide N-methyltransferase enables ISO
IBA		 (PMID:21823666), (PMID:23455543), (PMID:8182091)
GO_REF:0000033
(PMID:26168293), (PMID:8845860)		 RGD
GO_Central		 PMID:8182091 PMID:8845860 PMID:21823666 PMID:23455543 PMID:26168293 GO_REF:0000033 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655 		JBrowse link
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Term Annotations click to browse term
  molecular_function 21086
    catalytic activity 6127
      transferase activity 2447
        transferase activity, transferring one-carbon groups 214
          methyltransferase activity 203
            S-adenosylmethionine-dependent methyltransferase activity 169
              nicotinamide N-methyltransferase activity 1
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