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ONTOLOGY REPORT - ANNOTATIONS

Term:mitochondrial fusion
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Accession:GO:0008053 term browser browse the term
Definition:Merging of two or more mitochondria within a cell to form a single compartment.
Synonyms:exact_synonym: mitochondrion fusion
 related_synonym: mitochondrial membrane fusion
 alt_id: GO:1990613


show annotations for term's descendants           Sort by:
mitochondrial fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFG3L2 AFG3 like matrix AAA peptidase subunit 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20038678) Ensembl
MGI		 PMID:20038678 GO_REF:0000107 NCBI chr18:1,951,279...1,999,313
Ensembl chr18:17,062,250...17,109,400 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 acts_upstream_of_or_within ISO (PMID:16893972), (PMID:17035996) MGI PMID:16893972 PMID:17035996 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16893972), (PMID:17035996) Ensembl
MGI
TreeGrafter		 PMID:16893972 PMID:17035996 GO_REF:0000107 GO_REF:0000118 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468 		JBrowse link
G BCL2A1 BCL2 related protein A1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:58,925,853...58,935,122
Ensembl chr15:77,882,940...77,893,628 		JBrowse link
G CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 involved_in ISO (PMID:21081504) UniProt PMID:21081504 NCBI chr 7:124,758,547...125,056,898 JBrowse link
G FIS1 fission, mitochondrial 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:93,381,058...93,386,483
Ensembl chr 7:106,621,211...106,626,683 		JBrowse link
G GDAP1 ganglioside induced differentiation associated protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:70,854,665...70,900,532
Ensembl chr 8:72,528,869...72,545,346 		JBrowse link
G MFF mitochondrial fission factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:114,569,893...114,602,158
Ensembl chr2B:233,381,466...233,413,778 		JBrowse link
G MFN1 mitofusin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12527753) Ensembl
MGI
TreeGrafter
InterPro		 PMID:12527753 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:176,378,175...176,423,943
Ensembl chr 3:184,552,108...184,596,763 		JBrowse link
G MFN2 mitofusin 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22493254)
(PMID:12527753)		 RGD
MGI
TreeGrafter
InterPro
Ensembl		 PMID:12527753 PMID:14561718 PMID:22493254 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:1304446 NCBI chr 1:10,729,933...10,764,865
Ensembl chr 1:11,945,880...11,981,077 		JBrowse link
G MIEF1 mitochondrial elongation factor 1 NOT|involved_in ISO (PMID:23921378) UniProt PMID:23921378 NCBI chr22:20,408,502...20,424,327
Ensembl chr22:38,228,939...38,244,774 		JBrowse link
G MIEF2 mitochondrial elongation factor 2 NOT|involved_in ISO (PMID:23921378) UniProt PMID:23921378 NCBI chr17:32,805,453...32,810,668
Ensembl chr17:37,944,215...37,949,451 		JBrowse link
G MIGA1 mitoguardin 1 involved_in IEA InterPro
TreeGrafter
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr 1:76,999,588...77,095,686
Ensembl chr 1:79,084,279...79,178,604 		JBrowse link
G MIGA2 mitoguardin 2 involved_in IEA InterPro
TreeGrafter
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr 9:100,160,068...100,197,095
Ensembl chr 9:128,820,773...128,856,977 		JBrowse link
G NEXN nexilin F-actin binding protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:77,104,269...77,162,517
Ensembl chr 1:79,187,779...79,244,732 		JBrowse link
G NME3 NME/NM23 nucleoside diphosphate kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:392,694...394,106
Ensembl chr16:1,822,719...1,824,147 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:190,890,242...190,995,133
Ensembl chr 3:201,207,607...201,312,358 		JBrowse link
G PARL presenilin associated rhomboid like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:180,862,434...180,921,197
Ensembl chr 3:189,032,816...189,088,036 		JBrowse link
G PLD6 phospholipase D family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,084,634...34,091,470
Ensembl chr17:39,016,859...39,023,398 		JBrowse link
G RCC1L RCC1 like involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 7:82,016,477...82,065,189 JBrowse link
G THG1L tRNA-histidine guanylyltransferase 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:153,116,528...153,127,166
Ensembl chr 5:159,737,327...159,749,242 		JBrowse link
G USP30 ubiquitin specific peptidase 30 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:106,629,106...106,664,512
Ensembl chr12:110,022,959...110,058,335 		JBrowse link
mitochondrial inner membrane fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OPA1 OPA1 mitochondrial dynamin like GTPase involved_in ISO (PMID:28628083), (PMID:31922487), (PMID:32228866), (PMID:37612504), (PMID:37612506) UniProt PMID:28628083 PMID:31922487 PMID:32228866 PMID:37612504 PMID:37612506 NCBI chr 3:190,890,242...190,995,133
Ensembl chr 3:201,207,607...201,312,358 		JBrowse link
negative regulation of mitochondrial fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCK1 aarF domain containing kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:58,355,670...58,495,032
Ensembl chr14:77,556,389...77,695,344 		JBrowse link
G BNIP3 BCL2 interacting protein 3 involved_in ISO (PMID:20436456) BHF-UCL PMID:20436456 NCBI chr10:128,671,663...128,685,952
Ensembl chr10:132,858,211...132,871,634 		JBrowse link
G DNM1L dynamin 1 like involved_in ISO PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chr12:53,476,553...53,541,421
Ensembl chr12:56,077,504...56,142,376 		JBrowse link
G HUWE1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:45,746,228...45,897,250
Ensembl chr  X:53,855,404...54,005,366 		JBrowse link
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:19,454,792...19,463,527
Ensembl chr 1:20,496,356...20,505,281 		JBrowse link
G OMA1 OMA1 zinc metallopeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:57,549,404...57,811,246
Ensembl chr 1:59,448,436...59,516,170 		JBrowse link
G TFRC transferrin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:193,384,817...193,417,532
Ensembl chr 3:203,333,953...203,373,998 		JBrowse link
G VAT1 vesicle amine transport 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:14,301,543...14,309,955
Ensembl chr17:14,531,301...14,538,024 		JBrowse link
positive regulation of mitochondrial fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MFN1 mitofusin 1 ISO RGD PMID:24751540 RGD:13204834 NCBI chr 3:176,378,175...176,423,943
Ensembl chr 3:184,552,108...184,596,763 		JBrowse link
G MIEF1 mitochondrial elongation factor 1 involved_in ISO (PMID:33632269) UniProt PMID:33632269 NCBI chr22:20,408,502...20,424,327
Ensembl chr22:38,228,939...38,244,774 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase ISO RGD PMID:22442078 RGD:7829728 NCBI chr 3:190,890,242...190,995,133
Ensembl chr 3:201,207,607...201,312,358 		JBrowse link
G PLD6 phospholipase D family member 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24599962) MGI
Ensembl		 PMID:24599962 GO_REF:0000107 NCBI chr17:34,084,634...34,091,470
Ensembl chr17:39,016,859...39,023,398 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770 		JBrowse link
G YME1L1 YME1 like 1 ATPase involved_in ISO (PMID:33237841) UniProt PMID:33237841 NCBI chr10:27,220,951...27,263,841
Ensembl chr10:27,584,099...27,626,453 		JBrowse link
G ZDHHC6 zinc finger DHHC-type palmitoyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:109,021,160...109,038,445
Ensembl chr10:112,457,937...112,474,921 		JBrowse link
regulation of mitochondrial fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTCH2 mitochondrial carrier 2 involved_in ISO (MGI:6267820|PMID:30510213) UniProt PMID:30510213 MGI:6267820 NCBI chr11:47,566,884...47,596,711
Ensembl chr11:48,115,774...48,146,312 		JBrowse link
stress-induced mitochondrial fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STOML2 stomatin like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:34,950,387...34,953,707
Ensembl chr 9:35,755,790...35,759,091 		JBrowse link
G THG1L tRNA-histidine guanylyltransferase 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:153,116,528...153,127,166
Ensembl chr 5:159,737,327...159,749,242 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    cellular process 15499
      cellular component organization or biogenesis 6620
        cellular component organization 6401
          organelle organization 3612
            organelle fusion 175
              mitochondrial fusion 35
                mitochondrial inner membrane fusion 1
                mitochondrial outer membrane fusion 0
                negative regulation of mitochondrial fusion 8
                positive regulation of mitochondrial fusion 7
                regulation of mitochondrial fusion + 16
                stress-induced mitochondrial fusion 2
paths to the root