Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:mitochondrial fusion
go back to main search page
Accession:GO:0008053 term browser browse the term
Definition:Merging of two or more mitochondria within a cell to form a single compartment.
Synonyms:exact_synonym: mitochondrion fusion
 related_synonym: mitochondrial membrane fusion
 alt_id: GO:1990613



show annotations for term's descendants           Sort by:
mitochondrial fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afg3l1 AFG3 (ATPase family gene 3)-like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:51,508,612...51,535,773
Ensembl chr19:51,508,613...51,537,396
JBrowse link
G Afg3l2 AFG3 like matrix AAA peptidase subunit 2 acts_upstream_of_or_within ISO MGI:1928277 (PMID:20038678) RGD PMID:20038678 NCBI chr18:60,954,268...60,999,110
Ensembl chr18:60,954,268...60,999,110
JBrowse link
G Bak1 BCL2-antagonist/killer 1 acts_upstream_of_or_within ISO MGI:99702 (PMID:16893972), (PMID:17035996) RGD PMID:16893972 PMID:17035996 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within
ISO
ISS
IBA
(PMID:14769861)
GO_REF:0000024
GO_REF:0000033
MGI:1097161 (PMID:16893972), (PMID:17035996)
RGD
UniProt
GO_Central
PMID:14769861 PMID:16893972 PMID:17035996 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2a1 BCL2-related protein A1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
JBrowse link
G Chchd3 coiled-coil-helix-coiled-coil-helix domain containing 3 involved_in ISO (PMID:21081504) RGD PMID:21081504 NCBI chr 4:61,360,352...61,616,850
Ensembl chr 4:61,360,353...61,616,847
JBrowse link
G Fundc1 FUN14 domain containing 1 involved_in ISO FB:FBgn0026479|FB:FBgn0029891|FB:FBgn0032200 (PMID:37931419) RGD PMID:37931419 NCBI chr  X:5,083,635...5,100,293
Ensembl chr  X:5,083,617...5,100,284
JBrowse link
G Gdap1 ganglioside-induced differentiation-associated-protein 1 involved_in ISO
IBA
(PMID:21753178)
GO_REF:0000033
RGD
GO_Central
PMID:21753178 GO_REF:0000033 NCBI chr 5:1,932,613...1,951,691
Ensembl chr 5:1,932,613...2,030,061
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mfn1 mitofusin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
ISS
GO_REF:0000107
UniProtKB:Q80U63 (PMID:15899901), (PMID:24513856)
MGI:2450304 (PMID:12527753)
GO_REF:0000033
GO_REF:0000002
(PMID:12759376), (PMID:20436456), (PMID:23921378), (PMID:27920125), (PMID:28114303)
GO_REF:0000024
Ensembl
RGD
GO_Central
InterPro
UniProt
PMID:12527753 PMID:12759376 PMID:15899901 PMID:20436456 PMID:23921378 More... GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
JBrowse link
G Mfn2 mitofusin 2 involved_in
acts_upstream_of_or_within
IMP
ISO
IBA
IEA
ISS
UniProtKB:Q9H4I3 (PMID:23921378), (PMID:38843396)
UniProtKB:Q811U4 (PMID:15899901), (PMID:24513856)
MGI:2450306 (PMID:12527753), (PMID:22493254)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024
RGD
GO_Central
Ensembl
UniProt
PMID:12527753 PMID:15899901 PMID:22493254 PMID:23921378 PMID:24513856 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:1304446 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mief1 mitochondrial elongation factor 1 NOT|involved_in ISO (PMID:23921378) RGD PMID:23921378 NCBI chr 7:111,786,630...111,802,220
Ensembl chr 7:111,786,709...111,802,220
JBrowse link
G Mief2 mitochondrial elongation factor 2 NOT|involved_in ISO (PMID:23921378) RGD PMID:23921378 NCBI chr10:45,408,055...45,414,144
Ensembl chr10:45,408,082...45,414,144
JBrowse link
G Miga1 mitoguardin 1 involved_in ISO
IBA
(PMID:26711011)
GO_REF:0000033
RGD
GO_Central
PMID:26711011 GO_REF:0000033 NCBI chr 2:241,224,118...241,279,174
Ensembl chr 2:241,226,015...241,279,106
JBrowse link
G Miga2 mitoguardin 2 involved_in IBA
ISO
GO_REF:0000033
UniProtKB:Q9H4I3 (PMID:26711011), (PMID:38843396)
GO_Central
RGD
PMID:26711011 PMID:38843396 GO_REF:0000033 NCBI chr 3:13,636,235...13,658,895
Ensembl chr 3:13,636,238...13,658,896
JBrowse link
G Nme3 NME/NM23 nucleoside diphosphate kinase 3 involved_in ISO (PMID:30587587) RGD PMID:30587587 NCBI chr10:13,917,309...13,918,415
Ensembl chr10:13,917,403...13,918,359
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:15899901)
GO_REF:0000033
(PMID:17545159), (PMID:20185555), (PMID:20436456)
ParkinsonsUK-UCL
RGD
GO_Central
PMID:15899901 PMID:17545159 PMID:20185555 PMID:20436456 GO_REF:0000024 GO_REF:0000033 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISO (PMID:16713954) RGD PMID:16713954 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506
JBrowse link
G Pld6 phospholipase D family, member 6 involved_in ISO UniProtKB:Q9H4I3 (PMID:17028579), (PMID:38843396) RGD PMID:17028579 PMID:38843396 NCBI chr10:44,578,536...44,581,187
Ensembl chr10:44,577,675...44,581,077
JBrowse link
G Rcc1l RCC1 like involved_in ISO (PMID:28746876) RGD PMID:28746876 NCBI chr12:22,543,125...22,574,042
Ensembl chr12:22,543,734...22,574,036
JBrowse link
G Thg1l tRNA-histidine guanylyltransferase 1-like involved_in ISS
ISO
GO_REF:0000024
(PMID:25008184)
UniProt
RGD
PMID:25008184 GO_REF:0000024 NCBI chr10:30,387,929...30,396,579
Ensembl chr10:30,387,940...30,396,687
JBrowse link
G Trabd TraB domain containing involved_in ISO
IEA
(PMID:38843396)
GO_REF:0000107
RGD
Ensembl
PMID:38843396 GO_REF:0000107 NCBI chr 7:120,155,042...120,166,015
Ensembl chr 7:120,155,042...120,166,015
JBrowse link
G Usp30 ubiquitin specific peptidase 30 involved_in ISO (PMID:24513856) RGD PMID:24513856 NCBI chr12:42,501,345...42,555,311
Ensembl chr12:42,501,348...42,555,616
JBrowse link
mitochondrial inner membrane fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISO
ISS
IEA
(PMID:32228866)
(PMID:28628083)
(PMID:31922487), (PMID:37612504), (PMID:37612506)
GO_REF:0000024
GO_REF:0000107
(PMID:24703695), (PMID:28636943)
RGD
UniProt
Ensembl
PMID:24703695 PMID:28628083 PMID:28636943 PMID:31922487 PMID:32228866 More... GO_REF:0000024 GO_REF:0000107 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
negative regulation of mitochondrial fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adck1 aarF domain containing kinase 1 involved_in ISO (PMID:31125351) RGD PMID:31125351 NCBI chr 6:107,277,170...107,377,057
Ensembl chr 6:107,277,244...107,377,055
JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in ISO (PMID:20436456) RGD PMID:20436456 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Dnm1l dynamin 1-like involved_in IMP PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Huwe1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in ISO (PMID:26214738) RGD PMID:26214738 NCBI chr  X:20,873,795...21,001,378
Ensembl chr  X:20,873,795...21,001,262
JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:19407830) RGD PMID:19407830 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863
JBrowse link
G Oma1 OMA1 zinc metallopeptidase involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:22433842)
GO_REF:0000107
(PMID:20038677)
UniProt
RGD
Ensembl
PMID:20038677 PMID:22433842 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:118,083,728...118,136,980
Ensembl chr 5:118,083,728...118,136,980
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS GO_REF:0000024 ParkinsonsUK-UCL GO_REF:0000024 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Tfrc transferrin receptor involved_in ISO (PMID:26214738) RGD PMID:26214738 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Vat1 vesicle amine transport 1 involved_in ISO
IBA
(PMID:17105775)
GO_REF:0000033
RGD
GO_Central
PMID:17105775 GO_REF:0000033 NCBI chr10:86,389,549...86,397,167
Ensembl chr10:86,389,545...86,397,224
JBrowse link
positive regulation of mitochondrial fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfn1 mitofusin 1 IMP RGD PMID:24751540 RGD:13204834 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
JBrowse link
G Mief1 mitochondrial elongation factor 1 involved_in ISO
ISS
(PMID:33632269)
GO_REF:0000024
RGD
UniProt
PMID:33632269 GO_REF:0000024 NCBI chr 7:111,786,630...111,802,220
Ensembl chr 7:111,786,709...111,802,220
JBrowse link
G Msto1 misato mitochondrial distribution and morphology regulator 1 involved_in ISO (PMID:28554942) RGD PMID:28554942 NCBI chr 2:174,305,945...174,310,230
Ensembl chr 2:174,301,861...174,310,216
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase IMP RGD PMID:22442078 RGD:7829728 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Pld6 phospholipase D family, member 6 acts_upstream_of_or_within ISO (PMID:24599962) RGD PMID:24599962 NCBI chr10:44,578,536...44,581,187
Ensembl chr10:44,577,675...44,581,077
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
ISS
(PMID:23453807)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
ParkinsonsUK-UCL
PMID:23453807 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Yme1l1 YME1-like 1 ATPase involved_in ISO
IEA
ISS
(PMID:33237841)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:33237841 GO_REF:0000024 GO_REF:0000107 NCBI chr17:85,287,607...85,326,068
Ensembl chr17:85,287,554...85,326,335
JBrowse link
G Zdhhc6 zinc finger DHHC-type palmitoyltransferase 6 involved_in ISO (PMID:26214738) RGD PMID:26214738 NCBI chr 1:254,335,472...254,356,141
Ensembl chr 1:254,335,113...254,356,108
JBrowse link
regulation of mitochondrial fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtch2 mitochondrial carrier 2 involved_in ISO (PMID:30510213) RGD PMID:30510213 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189
JBrowse link
stress-induced mitochondrial fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stoml2 stomatin like 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:19360003)
UniProt
RGD
PMID:19360003 GO_REF:0000024 NCBI chr 5:57,256,227...57,259,824
Ensembl chr 5:57,256,220...57,259,920
JBrowse link
G Thg1l tRNA-histidine guanylyltransferase 1-like involved_in ISO
IEA
ISS
(PMID:25008184)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:25008184 GO_REF:0000024 GO_REF:0000107 NCBI chr10:30,387,929...30,396,579
Ensembl chr10:30,387,940...30,396,687
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20052
    cellular process 19130
      cellular component organization or biogenesis 7164
        cellular component organization 6910
          organelle organization 3691
            organelle fusion 173
              mitochondrial fusion 37
                mitochondrial inner membrane fusion 1
                mitochondrial outer membrane fusion 0
                negative regulation of mitochondrial fusion 9
                positive regulation of mitochondrial fusion 8
                regulation of mitochondrial fusion + 17
                stress-induced mitochondrial fusion 2
paths to the root