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ONTOLOGY REPORT - ANNOTATIONS


Term:blood coagulation, intrinsic pathway
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Accession:GO:0007597 term browser browse the term
Definition:A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X.
Comment:See also the biological process term 'blood coagulation, extrinsic pathway ; GO:0007598'.


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blood coagulation, intrinsic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H ISO
IEA
(PMID:4052628)
GO_REF:0000107
RGD
Ensembl
PMID:4052628 GO_REF:0000107 NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938
JBrowse link
G F8 coagulation factor VIII IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:2513867, PMID:21873635 RGD:1582368, RGD:13792537 NCBI chr18:367,862...399,242
Ensembl chr18:367,862...399,242
JBrowse link
regulation of blood coagulation, intrinsic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpinc1 serpin family C member 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    response to stimulus 10580
      protein activation cascade 14
        blood coagulation, intrinsic pathway 3
          negative regulation of blood coagulation, intrinsic pathway 0
          positive regulation of blood coagulation, intrinsic pathway 0
          regulation of blood coagulation, intrinsic pathway + 1
Path 2
Term Annotations click to browse term
  biological_process 20020
    response to stimulus 10580
      response to stress 4062
        response to wounding 625
          wound healing 435
            blood coagulation 187
              blood coagulation, fibrin clot formation 10
                blood coagulation, intrinsic pathway 3
                  negative regulation of blood coagulation, intrinsic pathway 0
                  positive regulation of blood coagulation, intrinsic pathway 0
                  regulation of blood coagulation, intrinsic pathway + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.