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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:blood coagulation, intrinsic pathway
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Accession:GO:0007597 term browser browse the term
Definition:A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X.
Comment:See also the biological process term 'blood coagulation, extrinsic pathway ; GO:0007598'.


show annotations for term's descendants           Sort by:
blood coagulation, intrinsic pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H involved_in ISO (PMID:4052628) RGD PMID:4052628 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329 		JBrowse link
G F8 coagulation factor VIII involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:2513867 GO_REF:0000033, RGD:1582368 NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857 		JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in ISO (PMID:10501658) RGD PMID:10501658 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774 		JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta involved_in ISO (PMID:10501658) RGD PMID:10501658 NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392 		JBrowse link
G Gp5 glycoprotein V (platelet) involved_in ISO
IEA		 (PMID:10501658)
GO_REF:0000107		 RGD
Ensembl		 PMID:10501658 GO_REF:0000107 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705 		JBrowse link
G Gp9 glycoprotein IX (platelet) involved_in ISO (PMID:10501658) RGD PMID:10501658 NCBI chr 4:120,235,500...120,237,110
Ensembl chr 4:120,235,421...120,237,110 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    multicellular organismal process 8921
      coagulation 206
        blood coagulation 198
          blood coagulation, fibrin clot formation 16
            blood coagulation, intrinsic pathway 6
              negative regulation of blood coagulation, intrinsic pathway 0
              positive regulation of blood coagulation, intrinsic pathway 0
              regulation of blood coagulation, intrinsic pathway + 0
Path 2
Term Annotations click to browse term
  biological_process 20413
    metabolic process 11835
      organic substance metabolic process 11328
        macromolecule metabolic process 9578
          macromolecule biosynthetic process 7463
            gene expression 7014
              protein maturation 562
                protein activation cascade 21
                  blood coagulation, fibrin clot formation 16
                    blood coagulation, intrinsic pathway 6
                      negative regulation of blood coagulation, intrinsic pathway 0
                      positive regulation of blood coagulation, intrinsic pathway 0
                      regulation of blood coagulation, intrinsic pathway + 0
paths to the root