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ONTOLOGY REPORT - ANNOTATIONS

Term:sex determination
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Accession:GO:0007530 term browser browse the term
Definition:Any process that establishes and transmits the specification of sexual status of an individual organism.
Synonyms:xref: Wikipedia:Sex-determination_system


show annotations for term's descendants           Sort by:
sex determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amh anti-Mullerian hormone involved_in ISO (MGI:69385|PMID:7954809) RGD PMID:7954809 MGI:69385 NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 involved_in ISO
IBA		 (MGI:3851651|PMID:19457926)
GO_REF:0000033		 RGD
GO_Central		 PMID:19457926 GO_REF:0000033 MGI:3851651 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 acts_upstream_of_or_within ISO MGI:98660 (PMID:9486644) RGD PMID:9486644 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24405868), (PMID:27378692), (PMID:27490115), (PMID:27610946), (PMID:27855412)		 UniProt
RGD		 PMID:24405868 PMID:27378692 PMID:27490115 PMID:27610946 PMID:27855412 GO_REF:0000024 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328 		JBrowse link
G Sox3 SRY-box transcription factor 3 involved_in ISO (PMID:21183788)
(MGI:5000178|PMID:21183788)		 RGD PMID:21183788 MGI:5000178 NCBI chr  X:139,308,608...139,310,687
Ensembl chr  X:139,309,329...139,310,678 		JBrowse link
G Sry sex determining region Y involved_in
acts_upstream_of_or_within		 ISO (MGI:6471836|PMID:33004521)
MGI:1352460 (PMID:9486644)		 RGD PMID:9486644 PMID:33004521 MGI:6471836 NCBI chr  Y:441,525...442,037 JBrowse link
G Tcf21 transcription factor 21 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:2148207 (PMID:10572052)		 UniProt
RGD		 PMID:10572052 GO_REF:0000024 NCBI chr 1:22,701,353...22,704,212
Ensembl chr 1:22,701,353...22,704,202 		JBrowse link
G Wt1 WT1 transcription factor involved_in
acts_upstream_of_or_within		 ISO
IEA
ISS		 (PMID:9815658)
MGI:2183642 (PMID:11509181)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:9815658 PMID:11509181 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643 		JBrowse link
female sex determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 Wnt family member 4 involved_in ISO (PMID:11283799) RGD PMID:11283799 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
female somatic sex determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxl2 forkhead box L2 acts_upstream_of_or_within ISO MGI:2182312 (PMID:15944199) RGD PMID:15944199 NCBI chr 8:99,512,971...99,514,500
Ensembl chr 8:99,513,303...99,514,427 		JBrowse link
germ-line sex determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmem184a transmembrane protein 184A acts_upstream_of_or_within ISO (PMID:18321981) RGD PMID:18321981 NCBI chr12:14,817,508...14,833,109
Ensembl chr12:14,822,898...14,832,065 		JBrowse link
male germ-line sex determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map3k4 mitogen activated protein kinase kinase kinase 4 acts_upstream_of_or_within ISO MGI:1856634 (PMID:6855886) RGD PMID:6855886 NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:2385468|MGI:2673819|MGI:3580900 (PMID:11431689), (PMID:16207837)		 UniProt
RGD		 PMID:11431689 PMID:16207837 GO_REF:0000024 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
male sex determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhh desert hedgehog signaling molecule acts_upstream_of_or_within ISO MGI:1095403 (PMID:17495005) RGD PMID:17495005 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406 		JBrowse link
G Dmrt1 doublesex and mab-3 related transcription factor 1 involved_in ISO (MGI:1926717|PMID:11040213), (MGI:4420727|PMID:20007774), (MGI:4839662|PMID:20951351) RGD PMID:11040213 PMID:20007774 PMID:20951351 MGI:1926717 MGI:4420727 MGI:4839662 NCBI chr 1:223,142,859...223,241,333
Ensembl chr 1:223,142,859...223,241,333 		JBrowse link
G Fgf9 fibroblast growth factor 9 acts_upstream_of_or_within ISO MGI:2135961|MGI:98371|MGI:98660|MGI:98957 (PMID:16700629) RGD PMID:16700629 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 IMP RGD PMID:7012206 RGD:9685140 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor acts_upstream_of_or_within ISO MGI:1926486 (PMID:14628051) RGD PMID:14628051 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Insr insulin receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857204 (PMID:14628051)		 Ensembl
RGD		 PMID:14628051 GO_REF:0000107 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Insrr insulin receptor-related receptor acts_upstream_of_or_within ISO MGI:2653019 (PMID:14628051) RGD PMID:14628051 NCBI chr 2:173,255,335...173,274,800
Ensembl chr 2:173,255,414...173,274,800 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2159321|MGI:98660 (PMID:12679814), (PMID:15944188)		 Ensembl
RGD		 PMID:12679814 PMID:15944188 GO_REF:0000107 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 involved_in ISO (PMID:10369247) RGD PMID:10369247 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328 		JBrowse link
G Ptgdr prostaglandin D2 receptor acts_upstream_of_or_within ISO (PMID:16185683) RGD PMID:16185683 NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679 		JBrowse link
G Sf1 splicing factor 1 acts_upstream_of_or_within ISO MGI:94891 (PMID:17495005) RGD PMID:17495005 NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330 		JBrowse link
G Six4 SIX homeobox 4 involved_in ISO (MGI:5532793|PMID:23987514) RGD PMID:23987514 MGI:5532793 NCBI chr 6:91,802,328...91,816,002
Ensembl chr 6:91,802,329...91,815,992 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO MGI:104723|MGI:98660 (PMID:16700629) RGD PMID:16700629 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Sry sex determining region Y acts_upstream_of_or_within
involved_in		 IEP
ISO		 MGI:104723|MGI:1352460|MGI:98371 (PMID:15879091), (PMID:16700629)
(MGI:6471836|PMID:33004521)		 RGD PMID:15879091 PMID:16700629 PMID:33004521 PMID:8430080 MGI:6471836, RGD:1598778 NCBI chr  Y:441,525...442,037 JBrowse link
male somatic sex determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856319 (PMID:5452809)		 Ensembl
RGD		 PMID:5452809 GO_REF:0000107 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
positive regulation of mating-type specific transcription, DNA-templated term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor IDA RGD PMID:9056263 RGD:405878085 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    developmental process 7008
      developmental process involved in reproduction 1229
        sex determination 25
          female sex determination + 2
          germ-line sex determination + 3
          male sex determination + 16
          mating type determination + 1
          primary sex determination + 2
          processes downstream of sex determination signal + 0
          somatic sex determination + 2
paths to the root