Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:mesodermal cell fate specification
go back to main search page
Accession:GO:0007501 term browser browse the term
Definition:The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
Comment:Note that this term was 'fate specification in mesoderm'. String of term was changed to correspond to format of sibling terms 'endoderm cell fate specification' and 'ectoderm cell fate specification'.
Synonyms:exact_synonym: mesoderm cell fate specification



show annotations for term's descendants           Sort by:
 
mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in IDA (MGI:3768605|PMID:17785448) UniProt PMID:17785448 MGI:3768605 NCBI chr 1:14,168,953...14,311,035
Ensembl chr 1:14,168,954...14,310,235
JBrowse link
G Hoxa11 homeobox A11 involved_in IDA (MGI:3768605|PMID:17785448) UniProt PMID:17785448 MGI:3768605 NCBI chr 6:52,242,105...52,245,810
Ensembl chr 6:52,242,106...52,245,810
JBrowse link
G Pax2 paired box 2 involved_in IDA (MGI:3768605|PMID:17785448) UniProt PMID:17785448 MGI:3768605 NCBI chr19:44,746,601...44,838,269
Ensembl chr19:44,756,045...44,837,871
JBrowse link
G Six2 sine oculis-related homeobox 2 involved_in IDA (MGI:3768605|PMID:17785448) UniProt PMID:17785448 MGI:3768605 NCBI chr17:85,662,736...85,688,254
Ensembl chr17:85,684,277...85,688,274
JBrowse link
axial mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nodal nodal acts_upstream_of_or_within IMP (MGI:2677178|PMID:14511481) MGI PMID:14511481 MGI:2677178 NCBI chr10:61,417,972...61,425,338
Ensembl chr10:61,417,972...61,425,338
JBrowse link
BMP signaling pathway involved in mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Etv2 ets variant 2 acts_upstream_of_or_within IDA (MGI:4415813|PMID:18462699) MGI PMID:18462699 MGI:4415813 NCBI chr 7:30,633,616...30,636,509
Ensembl chr 7:30,633,616...30,635,852
JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:30,545,876...30,549,496
Ensembl chr19:30,545,863...30,549,665
JBrowse link
G Mesp1 mesoderm posterior 1 involved_in IDA (MGI:4441249|PMID:18593560) BHF-UCL PMID:18593560 MGI:4441249 NCBI chr 7:79,792,241...79,793,590
Ensembl chr 7:79,792,241...79,793,788
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within IGI (MGI:3711603|PMID:17462603) MGI PMID:17462603 MGI:3711603 NCBI chr 3:83,765,750...83,774,314
Ensembl chr 3:83,766,321...83,774,316
JBrowse link
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a wingless-type MMTV integration site family, member 3A involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:59,248,036...59,290,751
Ensembl chr11:59,248,033...59,290,752
JBrowse link
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor, type 1A acts_upstream_of_or_within IGI (MGI:3702797|PMID:16943278) MGI PMID:16943278 MGI:3702797 NCBI chr14:34,411,061...34,503,336
Ensembl chr14:34,410,734...34,503,341
JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 acts_upstream_of_or_within IGI (MGI:3702797|PMID:16943278) MGI PMID:16943278 MGI:3702797 NCBI chr 8:25,518,759...25,575,718
Ensembl chr 8:25,513,654...25,575,718
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28652
    developmental process 7168
      cellular developmental process 4847
        cell fate specification 102
          mesodermal cell fate specification 12
            BMP signaling pathway involved in mesodermal cell fate specification 1
            axial mesodermal cell fate specification + 1
            intermediate mesodermal cell fate specification + 0
            lateral mesodermal cell fate specification + 2
            negative regulation of mesodermal cell fate specification + 3
            paraxial mesodermal cell fate specification + 0
            positive regulation of mesodermal cell fate specification + 1
            regulation of mesodermal cell fate specification + 6
            transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification + 0
Path 2
Term Annotations click to browse term
  biological_process 28652
    developmental process 7168
      anatomical structure development 6551
        multicellular organism development 5902
          embryo development 1359
            embryonic morphogenesis 687
              gastrulation 204
                formation of primary germ layer 128
                  mesoderm formation 75
                    mesodermal cell differentiation 32
                      mesodermal cell fate commitment 17
                        mesodermal cell fate specification 12
                          BMP signaling pathway involved in mesodermal cell fate specification 1
                          axial mesodermal cell fate specification + 1
                          intermediate mesodermal cell fate specification + 0
                          lateral mesodermal cell fate specification + 2
                          negative regulation of mesodermal cell fate specification + 3
                          paraxial mesodermal cell fate specification + 0
                          positive regulation of mesodermal cell fate specification + 1
                          regulation of mesodermal cell fate specification + 6
                          transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification + 0
paths to the root