Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:mesodermal cell fate specification
go back to main search page
Accession:GO:0007501 term browser browse the term
Definition:The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
Comment:Note that this term was 'fate specification in mesoderm'. String of term was changed to correspond to format of sibling terms 'endoderm cell fate specification' and 'ectoderm cell fate specification'.
Synonyms:exact_synonym: mesoderm cell fate specification



show annotations for term's descendants           Sort by:
 
mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EYA1 EYA transcriptional coactivator and phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:67,728,057...68,060,069
Ensembl chr 8:69,387,769...69,551,829
JBrowse link
G HOXA11 homeobox A11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:27,826,003...27,829,757
Ensembl chr 7:27,424,759...27,429,103
JBrowse link
G PAX2 paired box 2 involved_in ISO (MGI:3768605|PMID:17785448) UniProt PMID:17785448 MGI:3768605 NCBI chr10:97,344,978...97,429,086
Ensembl chr10:100,822,676...100,904,028
JBrowse link
G SIX2 SIX homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:45,109,414...45,113,887
Ensembl chr2A:46,039,582...46,044,035
JBrowse link
axial mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NODAL nodal growth differentiation factor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2677178|PMID:14511481) MGI
Ensembl
PMID:14511481 GO_REF:0000107 MGI:2677178 NCBI chr10:66,906,866...66,916,938
Ensembl chr10:69,433,959...69,443,972
JBrowse link
BMP signaling pathway involved in mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ETV2 ETS variant transcription factor 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4415813|PMID:18462699) MGI
Ensembl
PMID:18462699 GO_REF:0000107 MGI:4415813 NCBI chr19:32,571,829...32,575,083
Ensembl chr19:41,307,864...41,311,004
JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776
JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:68,440,626...68,441,935
Ensembl chr15:87,645,768...87,647,210
JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3711603|PMID:17462603) MGI
Ensembl
PMID:17462603 GO_REF:0000107 MGI:3711603 NCBI chr 4:146,123,075...146,131,543
Ensembl chr 4:157,944,733...157,953,258
JBrowse link
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT3A Wnt family member 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:203,409,294...203,463,214
Ensembl chr 1:208,628,706...208,674,469
JBrowse link
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3702797|PMID:16943278) MGI
Ensembl
PMID:16943278 GO_REF:0000107 MGI:3702797 NCBI chr10:83,185,040...83,353,239
Ensembl chr10:86,837,469...86,912,912
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (MGI:3702797|PMID:16943278) MGI PMID:16943278 MGI:3702797 NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15230
    developmental process 6200
      cellular developmental process 4038
        cell fate specification 83
          mesodermal cell fate specification 12
            BMP signaling pathway involved in mesodermal cell fate specification 1
            axial mesodermal cell fate specification + 1
            intermediate mesodermal cell fate specification + 0
            lateral mesodermal cell fate specification + 2
            negative regulation of mesodermal cell fate specification + 3
            paraxial mesodermal cell fate specification + 0
            positive regulation of mesodermal cell fate specification + 1
            regulation of mesodermal cell fate specification + 6
            transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification + 0
Path 2
Term Annotations click to browse term
  biological_process 15230
    developmental process 6200
      anatomical structure development 5768
        multicellular organism development 5268
          embryo development 1273
            embryonic morphogenesis 658
              gastrulation 187
                formation of primary germ layer 122
                  mesoderm formation 73
                    mesodermal cell differentiation 32
                      mesodermal cell fate commitment 17
                        mesodermal cell fate specification 12
                          BMP signaling pathway involved in mesodermal cell fate specification 1
                          axial mesodermal cell fate specification + 1
                          intermediate mesodermal cell fate specification + 0
                          lateral mesodermal cell fate specification + 2
                          negative regulation of mesodermal cell fate specification + 3
                          paraxial mesodermal cell fate specification + 0
                          positive regulation of mesodermal cell fate specification + 1
                          regulation of mesodermal cell fate specification + 6
                          transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification + 0
paths to the root