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ONTOLOGY REPORT - ANNOTATIONS

Term:endoderm development
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Accession:GO:0007492 term browser browse the term
Definition:The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues.


show annotations for term's descendants           Sort by:
endoderm development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arc activity-regulated cytoskeleton-associated protein acts_upstream_of_or_within ISO MGI:2386454 (MGI:1355000|PMID:10727859) RGD PMID:10727859 MGI:1355000 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:5705244|PMID:24835669)		 Ensembl
RGD		 PMID:24835669 GO_REF:0000107 MGI:5705244 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A acts_upstream_of_or_within ISO MGI:2158342 (MGI:3051920|PMID:15136140) RGD PMID:15136140 MGI:3051920 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Bptf bromodomain PHD finger transcription factor acts_upstream_of_or_within ISO MGI:3841299 (MGI:3840601|PMID:18974875) RGD PMID:18974875 MGI:3840601 NCBI chr10:91,980,279...92,082,731
Ensembl chr10:91,982,758...92,082,769 		JBrowse link
G Cfc1 cripto, FRL-1, cryptic family 1 acts_upstream_of_or_within ISO MGI:97451 (MGI:2136711|PMID:11412024) RGD PMID:11412024 MGI:2136711 NCBI chr 9:36,742,106...36,751,931
Ensembl chr 9:36,739,071...36,751,930 		JBrowse link
G Dab2 DAB adaptor protein 2 NOT|acts_upstream_of_or_within ISO (MGI:5319713|PMID:22525672) RGD PMID:22525672 MGI:5319713 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 acts_upstream_of_or_within ISO MGI:2387760 (MGI:3789532|PMID:18403408) RGD PMID:18403408 MGI:3789532 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Eomes eomesodermin acts_upstream_of_or_within ISO MGI:2656539|MGI:5698524 (MGI:5697986|PMID:26494787) RGD PMID:26494787 MGI:5697986 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316 		JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 acts_upstream_of_or_within ISO MGI:3822451 (MGI:3821807|PMID:18794329) RGD PMID:18794329 MGI:3821807 NCBI chr13:30,673,052...30,770,213
Ensembl chr13:30,669,764...30,768,360 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within
acts_upstream_of_or_within_positive_effect		 ISO MGI:1888710 (MGI:1888607|PMID:10926768) RGD PMID:10926768 MGI:1888607 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G Gdf1 growth differentiation factor 1 acts_upstream_of_or_within ISO MGI:95686 (MGI:3763867|PMID:17936261) RGD PMID:17936261 MGI:3763867 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,097,314...19,112,519 		JBrowse link
G Gdf3 growth differentiation factor 3 acts_upstream_of_or_within ISO MGI:3612535|MGI:95683 (MGI:3611720|PMID:16368929), (MGI:3763867|PMID:17936261) RGD PMID:16368929 PMID:17936261 MGI:3611720 MGI:3763867 NCBI chr 4:155,831,572...155,835,953
Ensembl chr 4:155,830,909...155,835,937 		JBrowse link
G Hdac1 histone deacetylase 1 acts_upstream_of_or_within ISO (MGI:3041938|PMID:15060137) RGD PMID:15060137 MGI:3041938 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hhex hematopoietically expressed homeobox acts_upstream_of_or_within ISO MGI:2177762 (MGI:3703395|PMID:16364283) RGD PMID:16364283 MGI:3703395 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042 		JBrowse link
G Hnf1b HNF1 homeobox B acts_upstream_of_or_within ISO MGI:1857856|MGI:2181390 (MGI:1346632|PMID:10518496), (MGI:1346633|PMID:10518495), (MGI:3807614|PMID:18635606) RGD PMID:10518495 PMID:10518496 PMID:18635606 MGI:1346632 MGI:1346633 MGI:3807614 NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888 		JBrowse link
G Kif16b kinesin family member 16B involved_in ISO (MGI:4889011|PMID:21238925) RGD PMID:21238925 MGI:4889011 NCBI chr 3:129,974,692...130,254,194
Ensembl chr 3:129,974,800...130,254,019 		JBrowse link
G Lhx1 LIM homeobox 1 acts_upstream_of_or_within ISO MGI:2656539|MGI:5698524 (MGI:5697986|PMID:26494787) RGD PMID:26494787 MGI:5697986 NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617 		JBrowse link
G Med12 mediator complex subunit 12 acts_upstream_of_or_within ISO MGI:4839486 (MGI:4839544|PMID:20589884) RGD PMID:20589884 MGI:4839544 NCBI chr  X:66,404,622...66,427,772
Ensembl chr  X:66,404,760...66,428,387 		JBrowse link
G Mixl1 Mix paired-like homeobox 1 acts_upstream_of_or_within ISO MGI:2387828 (MGI:2181739|PMID:12117810) RGD PMID:12117810 MGI:2181739 NCBI chr13:92,422,031...92,426,065
Ensembl chr13:92,422,031...92,426,065 		JBrowse link
G Nckap1 NCK-associated protein 1 acts_upstream_of_or_within ISO MGI:3578145 (MGI:3701029|PMID:16831833) RGD PMID:16831833 MGI:3701029 NCBI chr 3:65,417,450...65,491,769
Ensembl chr 3:65,417,453...65,492,217 		JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857494 (MGI:1335655|PMID:10208743), (MGI:78065|PMID:8557195)		 Ensembl
RGD		 PMID:8557195 PMID:10208743 GO_REF:0000107 MGI:1335655 MGI:78065 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO MGI:2158732 (MGI:2155575|PMID:11311163) RGD PMID:11311163 MGI:2155575 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
G Nog noggin acts_upstream_of_or_within ISO (MGI:5705244|PMID:24835669) RGD PMID:24835669 MGI:5705244 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO MGI:2684314 (MGI:2682520|PMID:14657333) RGD PMID:14657333 MGI:2682520 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Onecut1 one cut homeobox 1 acts_upstream_of_or_within ISO MGI:2179340 (MGI:1859126|PMID:10825208) RGD PMID:10825208 MGI:1859126 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277 		JBrowse link
G Otx2 orthodenticle homeobox 2 acts_upstream_of_or_within ISO MGI:109448 (MGI:2136711|PMID:11412024) RGD PMID:11412024 MGI:2136711 NCBI chr15:21,942,233...21,953,034
Ensembl chr15:21,943,191...21,953,416 		JBrowse link
G Pax9 paired box 9 acts_upstream_of_or_within ISO MGI:1857887 (MGI:2178212|PMID:11932925) RGD PMID:11932925 MGI:2178212 NCBI chr 6:74,186,749...74,203,508
Ensembl chr 6:74,182,568...74,203,506 		JBrowse link
G Pelo pelota mRNA surveillance and ribosome rescue factor acts_upstream_of_or_within ISO MGI:3764519|MGI:5705245 (MGI:5705244|PMID:24835669) RGD PMID:24835669 MGI:5705244 NCBI chr 2:46,797,853...46,799,621
Ensembl chr 2:46,797,853...46,799,746 		JBrowse link
G Pthlh parathyroid hormone-like hormone acts_upstream_of_or_within ISO (MGI:1326851|PMID:9921650) RGD PMID:9921650 MGI:1326851 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Smad2 SMAD family member 2 acts_upstream_of_or_within ISO MGI:1201674 (MGI:3618021|PMID:15183723) RGD PMID:15183723 MGI:3618021 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 acts_upstream_of_or_within ISO MGI:108051 (MGI:3618021|PMID:15183723) RGD PMID:15183723 MGI:3618021 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad4 SMAD family member 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1858049|MGI:2656539|MGI:5698524 (MGI:1195384|PMID:9420335), (MGI:5697986|PMID:26494787)
GO_REF:0000107
MGI:1858049 (MGI:1195384|PMID:9420335)		 RGD
Ensembl		 PMID:9420335 PMID:26494787 GO_REF:0000107 MGI:1195384 MGI:5697986 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Sox17 SRY-box transcription factor 17 acts_upstream_of_or_within
involved_in		 ISO MGI:2179440|MGI:3717121 (MGI:4421275|PMID:19913509), (MGI:4946462|PMID:21146513)
(MGI:2178090|PMID:11973269)		 RGD PMID:11973269 PMID:19913509 PMID:21146513 MGI:2178090 MGI:4421275 MGI:4946462 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO (MGI:1326851|PMID:9921650) RGD PMID:9921650 MGI:1326851 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnrc6a trinucleotide repeat containing adaptor 6A acts_upstream_of_or_within ISO MGI:4052360 (MGI:6094918|PMID:28811219) RGD PMID:28811219 MGI:6094918 NCBI chr 1:177,561,898...177,715,669
Ensembl chr 1:177,646,030...177,715,660 		JBrowse link
G Tnrc6c trinucleotide repeat containing adaptor 6C acts_upstream_of_or_within ISO MGI:4124681 (MGI:5315650|PMID:22187428) RGD PMID:22187428 MGI:5315650 NCBI chr10:102,908,958...102,979,543
Ensembl chr10:102,868,828...102,978,194 		JBrowse link
G Wnt8a Wnt family member 8A acts_upstream_of_or_within ISO (MGI:3609071|PMID:16256739) RGD PMID:16256739 MGI:3609071 NCBI chr18:26,137,690...26,143,283
Ensembl chr18:26,137,690...26,143,283 		JBrowse link
cell migration involved in mesendoderm migration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO MGI:2150346 (MGI:1341493|PMID:10421635) RGD PMID:10421635 MGI:1341493 NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
endoderm formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO MGI:1858007|MGI:2148567|MGI:4418897 (MGI:3625553|PMID:12194849), (MGI:5498579|PMID:23824574) RGD PMID:12194849 PMID:23824574 MGI:3625553 MGI:5498579 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 acts_upstream_of_or_within ISO (MGI:4415813|PMID:18462699) RGD PMID:18462699 MGI:4415813 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Dusp1 dual specificity phosphatase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp2 dual specificity phosphatase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499 		JBrowse link
G Dusp4 dual specificity phosphatase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138 		JBrowse link
G Dusp5 dual specificity phosphatase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818 		JBrowse link
G Eomes eomesodermin acts_upstream_of_or_within
involved_in		 ISO MGI:3774028 (MGI:4887279|PMID:21245162), (MGI:5293253|PMID:21822279)
(MGI:3772748|PMID:18171685)		 RGD PMID:18171685 PMID:21245162 PMID:21822279 MGI:3772748 MGI:4887279 MGI:5293253 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316 		JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of_or_within ISO MGI:2179511 (MGI:77407|PMID:8582296) RGD PMID:8582296 MGI:77407 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Lhx1 LIM homeobox 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1857848 (MGI:3487194|PMID:15355796)		 UniProt
RGD		 PMID:15355796 GO_REF:0000024 MGI:3487194 NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617 		JBrowse link
G Mixl1 Mix paired-like homeobox 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:2387829 (MGI:3695524|PMID:17151016)		 RGD PMID:17151016 PMID:21873635 MGI:3695524, RGD:13792537 NCBI chr13:92,422,031...92,426,065
Ensembl chr13:92,422,031...92,426,065 		JBrowse link
G Nog noggin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:4415813|PMID:18462699)		 Ensembl
RGD		 PMID:18462699 GO_REF:0000107 MGI:4415813 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Smad2 SMAD family member 2 acts_upstream_of_or_within ISO (MGI:5293253|PMID:21822279) RGD PMID:21822279 MGI:5293253 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in ISO (PMID:18682240) RGD PMID:18682240 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Sox7 SRY-box transcription factor 7 involved_in ISO (PMID:18682240) RGD PMID:18682240 NCBI chr15:38,180,503...38,187,264
Ensembl chr15:38,180,503...38,187,264 		JBrowse link
G Tnrc6c trinucleotide repeat containing adaptor 6C acts_upstream_of_or_within ISO MGI:4124681 (MGI:5315650|PMID:22187428) RGD PMID:22187428 MGI:5315650 NCBI chr10:102,908,958...102,979,543
Ensembl chr10:102,868,828...102,978,194 		JBrowse link
endodermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col11a1 collagen type XI alpha 1 chain involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853 		JBrowse link
G Col12a1 collagen type XII alpha 1 chain involved_in ISO
IBA		 (PMID:23154389)
PMID:21873635		 RGD PMID:23154389 PMID:21873635 RGD:13792537 NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597 		JBrowse link
G Col7a1 collagen type VII alpha 1 chain involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr 8:109,604,877...109,637,252
Ensembl chr 8:109,604,861...109,637,252 		JBrowse link
G Col8a1 collagen type VIII alpha 1 chain involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424 		JBrowse link
G Fn1 fibronectin 1 involved_in ISO
IEA		 (PMID:23154389)
GO_REF:0000107		 RGD
Ensembl		 PMID:23154389 GO_REF:0000107 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Gata6 GATA binding protein 6 acts_upstream_of_or_within ISO MGI:2177785 (MGI:1315079|PMID:9832509) RGD PMID:9832509 MGI:1315079 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Grb2 growth factor receptor bound protein 2 acts_upstream_of_or_within ISO (MGI:3689690|PMID:16908534) RGD PMID:16908534 MGI:3689690 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISO
ISS		 (PMID:17624332)
GO_REF:0000024		 RGD
UniProt		 PMID:17624332 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Hsbp1 heat shock factor binding protein 1 acts_upstream_of_or_within ISO (MGI:5553204|PMID:24380799) RGD PMID:24380799 MGI:5553204 NCBI chr19:47,401,039...47,405,373
Ensembl chr19:47,400,966...47,435,821 		JBrowse link
G Inhba inhibin subunit beta A involved_in ISO (PMID:21828274) RGD PMID:21828274 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Itga4 integrin subunit alpha 4 involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715 		JBrowse link
G Itga5 integrin subunit alpha 5 involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837 		JBrowse link
G Itga7 integrin subunit alpha 7 involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr 7:1,360,125...1,388,886
Ensembl chr 7:1,359,940...1,388,450 		JBrowse link
G Itgav integrin subunit alpha V involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Itgb2 integrin subunit beta 2 involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Itgb5 integrin subunit beta 5 involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472 		JBrowse link
G Lama3 laminin subunit alpha 3 involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr18:3,523,168...3,751,722
Ensembl chr18:3,523,133...3,751,353 		JBrowse link
G Lamb1 laminin subunit beta 1 involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585 		JBrowse link
G Lamb3 laminin subunit beta 3 involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:3689690|PMID:16908534)
GO_REF:0000107		 RGD
Ensembl		 PMID:16908534 GO_REF:0000107 MGI:3689690 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Mixl1 Mix paired-like homeobox 1 involved_in ISO (MGI:5447921|PMID:19038793) RGD PMID:19038793 MGI:5447921 NCBI chr13:92,422,031...92,426,065
Ensembl chr13:92,422,031...92,426,065 		JBrowse link
G Mmp14 matrix metallopeptidase 14 involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Mmp15 matrix metallopeptidase 15 involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943 		JBrowse link
G Mmp2 matrix metallopeptidase 2 involved_in ISO
IEA		 (PMID:23154389)
GO_REF:0000107		 RGD
Ensembl		 PMID:23154389 GO_REF:0000107 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp8 matrix metallopeptidase 8 involved_in IEA
ISO		 GO_REF:0000107
(PMID:23154389)		 Ensembl
RGD		 PMID:23154389 GO_REF:0000107 NCBI chr 8:4,724,009...4,732,956
Ensembl chr 8:4,724,029...4,733,520 		JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in IEA
ISO		 GO_REF:0000107
(PMID:23154389)		 Ensembl
RGD		 PMID:23154389 GO_REF:0000107 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Nodal nodal growth differentiation factor involved_in ISO (PMID:21741376) RGD PMID:21741376 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3640222|PMID:16466956)
GO_REF:0000107		 RGD
Ensembl		 PMID:16466956 GO_REF:0000107 MGI:3640222 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011 		JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase involved_in ISO (MGI:5908786|PMID:25242323) RGD PMID:25242323 MGI:5908786 NCBI chr 8:110,511,808...110,597,489
Ensembl chr 8:110,511,772...110,597,489 		JBrowse link
G Sox17 SRY-box transcription factor 17 acts_upstream_of ISO (MGI:3764939|PMID:17940068) RGD PMID:17940068 MGI:3764939 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Vtn vitronectin involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr10:63,394,732...63,397,812
Ensembl chr10:63,394,719...63,397,810 		JBrowse link
endodermal cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc73 cell division cycle 73 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:3849235|PMID:19345177)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19345177 GO_REF:0000024 GO_REF:0000107 MGI:3849235 NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1858007|MGI:2148567 (MGI:3625553|PMID:12194849)
GO_REF:0000107		 RGD
Ensembl		 PMID:12194849 GO_REF:0000107 MGI:3625553 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component involved_in ISO (MGI:3849235|PMID:19345177) RGD PMID:19345177 MGI:3849235 NCBI chr 1:165,137,277...165,167,303
Ensembl chr 1:165,137,215...165,167,303 		JBrowse link
G Leo1 LEO1 homolog, Paf1/RNA polymerase II complex component involved_in ISS
ISO		 GO_REF:0000024
(MGI:3849235|PMID:19345177)		 UniProt
RGD		 PMID:19345177 GO_REF:0000024 MGI:3849235 NCBI chr 8:76,199,547...76,223,983
Ensembl chr 8:76,199,099...76,223,983 		JBrowse link
G Paf1 PAF1 homolog, Paf1/RNA polymerase II complex component involved_in ISS
ISO		 GO_REF:0000024
(MGI:3849235|PMID:19345177)		 UniProt
RGD		 PMID:19345177 GO_REF:0000024 MGI:3849235 NCBI chr 1:83,683,654...83,689,233
Ensembl chr 1:83,668,813...83,689,237 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (MGI:1355046|PMID:10742100) RGD PMID:10742100 MGI:1355046 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Rtf1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) involved_in ISO (MGI:3849235|PMID:19345177) RGD PMID:19345177 MGI:3849235 NCBI chr 3:106,659,363...106,718,970
Ensembl chr 3:106,659,308...106,718,970 		JBrowse link
endodermal cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata6 GATA binding protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:4442295|PMID:20308546)		 Ensembl
RGD		 PMID:20308546 GO_REF:0000107 MGI:4442295 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Sox17 SRY-box transcription factor 17 acts_upstream_of_or_within ISO (MGI:4442295|PMID:20308546) RGD PMID:20308546 MGI:4442295 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:3774028 (MGI:4887279|PMID:21245162)		 RGD PMID:21245162 PMID:21873635 MGI:4887279, RGD:13792537 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316 		JBrowse link
G Hnf1b HNF1 homeobox B acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1857856 (MGI:3807614|PMID:18635606)
GO_REF:0000107		 RGD
Ensembl		 PMID:18635606 GO_REF:0000107 MGI:3807614 NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888 		JBrowse link
G Nanog Nanog homeobox acts_upstream_of_or_within ISO (PMID:20713518) RGD PMID:20713518 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (PMID:20713518) RGD PMID:20713518 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in ISO (MGI:4946573|PMID:21305474) RGD PMID:21305474 MGI:4946573 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:21245162) RGD PMID:21245162 NCBI chr 2:117,536,929...117,539,338
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
mesendoderm development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A acts_upstream_of_or_within ISO MGI:2158342 (MGI:3051920|PMID:15136140) RGD PMID:15136140 MGI:3051920 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Eomes eomesodermin acts_upstream_of ISO MGI:2656539|MGI:5698524 (MGI:5697986|PMID:26494787) RGD PMID:26494787 MGI:5697986 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316 		JBrowse link
G Foxa2 forkhead box A2 acts_upstream_of ISO MGI:2656539|MGI:5698524 (MGI:5697986|PMID:26494787) RGD PMID:26494787 MGI:5697986 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Ldb1 LIM domain binding 1 acts_upstream_of ISO MGI:2656539|MGI:5698524 (MGI:5697986|PMID:26494787) RGD PMID:26494787 MGI:5697986 NCBI chr 1:244,864,168...244,890,007
Ensembl chr 1:244,877,173...244,890,013 		JBrowse link
G Lhx1 LIM homeobox 1 acts_upstream_of ISO MGI:2656539|MGI:5698524 (MGI:5697986|PMID:26494787) RGD PMID:26494787 MGI:5697986 NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617 		JBrowse link
G Nodal nodal growth differentiation factor involved_in
acts_upstream_of_or_within		 ISO (PMID:21741376)
MGI:2158732 (MGI:2155575|PMID:11311163), (MGI:2677178|PMID:14511481)		 RGD PMID:11311163 PMID:14511481 PMID:21741376 MGI:2155575 MGI:2677178 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
G Otx2 orthodenticle homeobox 2 acts_upstream_of ISO MGI:2656539|MGI:5698524 (MGI:5697986|PMID:26494787) RGD PMID:26494787 MGI:5697986 NCBI chr15:21,942,233...21,953,034
Ensembl chr15:21,943,191...21,953,416 		JBrowse link
G Smad4 SMAD family member 4 acts_upstream_of ISO MGI:2656539|MGI:5698524 (MGI:5697986|PMID:26494787) RGD PMID:26494787 MGI:5697986 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Ssbp3 single stranded DNA binding protein 3 acts_upstream_of ISO MGI:2656539|MGI:5698524 (MGI:5697986|PMID:26494787) RGD PMID:26494787 MGI:5697986 NCBI chr 5:121,691,370...121,828,035
Ensembl chr 5:121,691,393...121,827,992 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5784967|PMID:24733888)		 UniProt
RGD		 PMID:24733888 GO_REF:0000024 MGI:5784967 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748 		JBrowse link
negative regulation of endodermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col5a1 collagen type V alpha 1 chain involved_in ISO
IEA		 (PMID:23154389)
GO_REF:0000107		 RGD
Ensembl		 PMID:23154389 GO_REF:0000107 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588 		JBrowse link
G Col5a2 collagen type V alpha 2 chain involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr 9:47,448,736...47,598,396
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
positive regulation of endodermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Macroh2a1 macroH2A.1 histone involved_in ISO (PMID:23595991) RGD PMID:23595991 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3689690|PMID:16908534)
GO_REF:0000107		 RGD
Ensembl		 PMID:16908534 GO_REF:0000107 MGI:3689690 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Sox17 SRY-box transcription factor 17 acts_upstream_of_or_within ISO (MGI:3764939|PMID:17940068) RGD PMID:17940068 MGI:3764939 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19898
    developmental process 7021
      anatomical structure development 6456
        tissue development 2243
          endoderm development 91
            endoderm formation + 59
            mesendoderm development + 11
paths to the root