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ONTOLOGY REPORT - ANNOTATIONS


Term:salivary gland morphogenesis
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Accession:GO:0007435 term browser browse the term
Definition:The process in which the anatomical structures of the salivary gland are generated and organized.


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salivary gland morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp7 bone morphogenetic protein 7 acts_upstream_of_or_within ISO MGI:1857654 (MGI:2158598|PMID:11731698) RGD PMID:11731698 MGI:2158598 NCBI chr 3:161,639,915...161,716,938 JBrowse link
G Ctnnd1 catenin delta 1 acts_upstream_of_or_within ISO MGI:3617486 (MGI:3614610|PMID:16399075) RGD PMID:16399075 MGI:3614610 NCBI chr 3:69,683,328...69,734,550 JBrowse link
G Egfr epidermal growth factor receptor acts_upstream_of_or_within ISO MGI:1935113 (MGI:1934551|PMID:10521784) RGD PMID:10521784 MGI:1934551 NCBI chr14:91,176,931...91,349,722 JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (MGI:3530190|PMID:15654336) RGD PMID:15654336 MGI:3530190 NCBI chr 2:50,801,897...50,875,428 JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (MGI:2389013|PMID:12421715) RGD PMID:12421715 MGI:2389013 NCBI chr16:66,492,445...66,546,731 JBrowse link
G Pax6 paired box 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856158 (MGI:2158598|PMID:11731698)
Ensembl
RGD
PMID:11731698 GO_REF:0000107 MGI:2158598 NCBI chr 3:92,128,772...92,157,022 JBrowse link
G Polb DNA polymerase beta acts_upstream_of_or_within ISO MGI:5427084 (MGI:5553198|PMID:24388753) RGD PMID:24388753 MGI:5553198 NCBI chr16:69,379,438...69,402,710 JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:18080134)
AgBase
RGD
PMID:18080134 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848 JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:18080134)
AgBase
RGD
PMID:18080134 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771 JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:18080134)
AgBase
RGD
PMID:18080134 GO_REF:0000024 NCBI chr 6:105,704,058...105,726,661 JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 acts_upstream_of_or_within ISO MGI:3830633 (MGI:3830176|PMID:16289463) RGD PMID:16289463 MGI:3830176 NCBI chr 9:105,533,116...105,567,525 JBrowse link
branch elongation involved in salivary gland morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (MGI:3703378|PMID:15972105) RGD PMID:15972105 MGI:3703378 NCBI chr 2:50,801,897...50,875,428 JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:1099809|MGI:2153811 (MGI:3703378|PMID:15972105) RGD PMID:15972105 MGI:3703378 NCBI chr 1:184,745,418...184,850,655 JBrowse link
branching involved in salivary gland morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp7 bone morphogenetic protein 7 acts_upstream_of_or_within ISO MGI:1857654 (MGI:2158598|PMID:11731698) RGD PMID:11731698 MGI:2158598 NCBI chr 3:161,639,915...161,716,938 JBrowse link
G Dag1 dystroglycan 1 acts_upstream_of_or_within ISO (MGI:2156962|PMID:11798066) RGD PMID:11798066 MGI:2156962 NCBI chr 8:108,890,926...108,955,611 JBrowse link
G Esrp1 epithelial splicing regulatory protein 1 acts_upstream_of_or_within ISO MGI:1924661 (MGI:5699497|PMID:26371508) RGD PMID:26371508 MGI:5699497 NCBI chr 5:24,427,611...24,482,157 JBrowse link
G Esrp2 epithelial splicing regulatory protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1917326 (MGI:5699497|PMID:26371508)
Ensembl
RGD
PMID:26371508 GO_REF:0000107 MGI:5699497 NCBI chr19:34,034,559...34,041,726 JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:95523 (MGI:3703378|PMID:15972105), (MGI:3813176|PMID:18559345) RGD PMID:15972105 PMID:18559345 MGI:3703378 MGI:3813176 NCBI chr 2:50,801,897...50,875,428 JBrowse link
G Fgf7 fibroblast growth factor 7 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3813176|PMID:18559345)
Ensembl
RGD
PMID:18559345 GO_REF:0000107 MGI:3813176 NCBI chr 3:113,280,448...113,333,279 JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO MGI:2686826|MGI:98297 (MGI:3039063|PMID:15042696), (MGI:3051949|PMID:15063181) RGD PMID:15042696 PMID:15063181 MGI:3039063 MGI:3051949 NCBI chr 1:244,584,477...244,590,359 JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (MGI:2389013|PMID:12421715), (MGI:3813176|PMID:18559345) RGD PMID:12421715 PMID:18559345 MGI:2389013 MGI:3813176 NCBI chr16:66,492,445...66,546,731 JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:2153814 (MGI:2158598|PMID:11731698) RGD PMID:11731698 MGI:2158598 NCBI chr 1:184,745,418...184,850,655 JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within ISO (MGI:1932624|PMID:11275690) RGD PMID:11275690 MGI:1932624 NCBI chr 4:5,214,602...5,219,178 JBrowse link
G Lama1 laminin subunit alpha 1 acts_upstream_of_or_within ISO (MGI:2156962|PMID:11798066) RGD PMID:11798066 MGI:2156962 NCBI chr 9:107,692,770...107,816,847 JBrowse link
G Lama5 laminin subunit alpha 5 acts_upstream_of_or_within ISO (MGI:2678847|PMID:14568553) RGD PMID:14568553 MGI:2678847 NCBI chr 3:167,270,296...167,318,370 JBrowse link
G Pdgfb platelet derived growth factor subunit B acts_upstream_of_or_within ISO (MGI:3813176|PMID:18559345) RGD PMID:18559345 MGI:3813176 NCBI chr 7:111,539,444...111,557,984 JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857796|MGI:99604 (MGI:3039063|PMID:15042696)
Ensembl
RGD
PMID:15042696 GO_REF:0000107 MGI:3039063 NCBI chr 4:6,954,017...6,963,170 JBrowse link
G Tgm2 transglutaminase 2 acts_upstream_of_or_within ISO (MGI:3588002|PMID:15970210) RGD PMID:15970210 MGI:3588002 NCBI chr 3:146,772,684...146,801,924 JBrowse link
dichotomous subdivision of terminal units involved in salivary gland branching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nrp1 neuropilin 1 acts_upstream_of_or_within ISO MGI:107558 (MGI:3720502|PMID:17626059) RGD PMID:17626059 MGI:3720502 NCBI chr19:56,359,455...56,514,628 JBrowse link
G Plxna1 plexin A1 acts_upstream_of_or_within ISO (MGI:3720502|PMID:17626059) RGD PMID:17626059 MGI:3720502 NCBI chr 4:121,737,934...121,782,901 JBrowse link
G Plxnd1 plexin D1 acts_upstream_of_or_within ISO (MGI:3720502|PMID:17626059) RGD PMID:17626059 MGI:3720502 NCBI chr 4:149,002,784...149,043,097 JBrowse link
G Sema3a semaphorin 3A acts_upstream_of_or_within ISO MGI:106206 (MGI:3720502|PMID:17626059) RGD PMID:17626059 MGI:3720502 NCBI chr 4:21,282,398...21,754,834 JBrowse link
G Sema3c semaphorin 3C acts_upstream_of_or_within ISO (MGI:3720502|PMID:17626059) RGD PMID:17626059 MGI:3720502 NCBI chr 4:17,583,212...17,747,234 JBrowse link
epithelial cell proliferation involved in salivary gland morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647|MGI:95523 (MGI:3703378|PMID:15972105) RGD PMID:15972105 MGI:3703378 NCBI chr 2:50,801,897...50,875,428 JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:1099809|MGI:2153811 (MGI:3703378|PMID:15972105) RGD PMID:15972105 MGI:3703378 NCBI chr 1:184,745,418...184,850,655 JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within ISO (MGI:1932624|PMID:11275690) RGD PMID:11275690 MGI:1932624 NCBI chr 4:5,214,602...5,219,178 JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:1928654 (MGI:1861552|PMID:10906459)
UniProt
RGD
PMID:10906459 GO_REF:0000024 MGI:1861552 NCBI chr15:44,473,851...44,476,443 JBrowse link
G Pdgfb platelet derived growth factor subunit B acts_upstream_of_or_within ISO (MGI:3813176|PMID:18559345) RGD PMID:18559345 MGI:3813176 NCBI chr 7:111,539,444...111,557,984 JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3039063|PMID:15042696)
Ensembl
RGD
PMID:15042696 GO_REF:0000107 MGI:3039063 NCBI chr 4:6,954,017...6,963,170 JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (MGI:1931422|PMID:11241200) RGD PMID:11241200 MGI:1931422 NCBI chr20:3,622,011...3,624,629 JBrowse link
regulation of branching involved in salivary gland morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btbd7 BTB domain containing 7 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:4820442|PMID:20671187)
PMID:21873635
RGD PMID:20671187, PMID:21873635 MGI:4820442, RGD:13792537 NCBI chr 6:121,920,365...122,010,114 JBrowse link
G Cdh1 cadherin 1 acts_upstream_of_or_within ISO (MGI:3826736|PMID:18816447) RGD PMID:18816447 MGI:3826736 NCBI chr19:34,492,371...34,561,775 JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within ISO (MGI:4820442|PMID:20671187) RGD PMID:20671187 MGI:4820442 NCBI chr11:86,183,800...86,186,109 JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (MGI:1931422|PMID:11241200) RGD PMID:11241200 MGI:1931422 NCBI chr20:3,622,011...3,624,629 JBrowse link
regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:3813176|PMID:18559345)
UniProt
RGD
PMID:18559345 GO_REF:0000024 MGI:3813176 NCBI chr12:15,645,549...15,667,056 JBrowse link
regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ntn4 netrin 4 acts_upstream_of_or_within ISO (MGI:3722516|PMID:17588941) RGD PMID:17588941 MGI:3722516 NCBI chr 7:28,186,611...28,300,390 JBrowse link
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO (MGI:3813176|PMID:18559345) RGD PMID:18559345 MGI:3813176 NCBI chr 2:50,801,897...50,875,428 JBrowse link
G Fgf7 fibroblast growth factor 7 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3813176|PMID:18559345)
Ensembl
RGD
PMID:18559345 GO_REF:0000107 MGI:3813176 NCBI chr 3:113,280,448...113,333,279 JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (MGI:3813176|PMID:18559345) RGD PMID:18559345 MGI:3813176 NCBI chr16:66,492,445...66,546,731 JBrowse link
G Hgf hepatocyte growth factor acts_upstream_of_or_within ISO (MGI:2677549|PMID:14517989)
(PMID:14517989)
RGD PMID:14517989 MGI:2677549 NCBI chr 4:18,673,736...18,745,582 JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:2677549|PMID:14517989) RGD PMID:14517989 MGI:2677549 NCBI chr 4:45,790,456...45,898,139 JBrowse link
salivary gland cavitation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh1 cadherin 1 acts_upstream_of_or_within ISO (MGI:3826736|PMID:18816447) RGD PMID:18816447 MGI:3826736 NCBI chr19:34,492,371...34,561,775 JBrowse link
G Eda ectodysplasin-A acts_upstream_of_or_within ISO (MGI:3617077|PMID:12629675) RGD PMID:12629675 MGI:3617077 NCBI chr  X:65,078,454...65,480,172 JBrowse link
G Edar ectodysplasin-A receptor acts_upstream_of_or_within ISO (MGI:3617077|PMID:12629675) RGD PMID:12629675 MGI:3617077 NCBI chr20:26,587,836...26,666,543 JBrowse link
G Nfib nuclear factor I/B acts_upstream_of_or_within ISO MGI:3530139 (MGI:5616978|PMID:25403566) RGD PMID:25403566 MGI:5616978 NCBI chr 5:96,759,208...96,973,092 JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3611172|PMID:16332353)
Ensembl
RGD
PMID:16332353 GO_REF:0000107 MGI:3611172 NCBI chr 4:6,954,017...6,963,170 JBrowse link
G Tgm2 transglutaminase 2 acts_upstream_of_or_within ISO (MGI:3588002|PMID:15970210) RGD PMID:15970210 MGI:3588002 NCBI chr 3:146,772,684...146,801,924 JBrowse link
submandibular salivary gland formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc42 cell division cycle 42 IEP RGD PMID:18784978 RGD:5688282 NCBI chr 5:149,555,069...149,593,239 JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (MGI:3688470|PMID:11062007) RGD PMID:11062007 MGI:3688470 NCBI chr 2:50,801,897...50,875,428 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    developmental process 6768
      anatomical structure morphogenesis 2884
        animal organ morphogenesis 1159
          gland morphogenesis 168
            salivary gland morphogenesis 41
              adult salivary gland morphogenesis 0
              branching involved in salivary gland morphogenesis + 28
              epithelial cell proliferation involved in salivary gland morphogenesis 7
              larval salivary gland morphogenesis 0
              positive regulation of salivary gland formation by mesenchymal-epithelial signaling 0
              salivary gland cavitation + 6
              salivary gland histolysis + 0
              submandibular salivary gland formation 2
Path 2
Term Annotations click to browse term
  biological_process 19492
    developmental process 6768
      anatomical structure development 6195
        multicellular organism development 5632
          system development 5300
            animal organ development 4060
              gland development 665
                gland morphogenesis 168
                  salivary gland morphogenesis 41
                    adult salivary gland morphogenesis 0
                    branching involved in salivary gland morphogenesis + 28
                    epithelial cell proliferation involved in salivary gland morphogenesis 7
                    larval salivary gland morphogenesis 0
                    positive regulation of salivary gland formation by mesenchymal-epithelial signaling 0
                    salivary gland cavitation + 6
                    salivary gland histolysis + 0
                    submandibular salivary gland formation 2
paths to the root