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ONTOLOGY REPORT - ANNOTATIONS

Term:ventral midline development
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Accession:GO:0007418 term browser browse the term
Definition:The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate.


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ventral midline development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli1 GLI family zinc finger 1 acts_upstream_of_or_within ISO MGI:95728 (PMID:10725236) RGD PMID:10725236 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1857509|MGI:95727 (PMID:10725236) RGD PMID:10725236 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
floor plate formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk20 cyclin-dependent kinase 20 acts_upstream_of_or_within ISO MGI:6113512 (PMID:28817564) RGD PMID:28817564 NCBI chr17:701,122...707,869
Ensembl chr17:701,124...707,826 		JBrowse link
G Cluap1 clusterin associated protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4363468 (PMID:23351563)		 Ensembl
RGD		 PMID:23351563 GO_REF:0000107 NCBI chr10:11,587,963...11,619,711
Ensembl chr10:11,588,017...11,619,711 		JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1857509 (PMID:9636069), (PMID:9655799) RGD PMID:9636069 PMID:9655799 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
ventral midline determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smo smoothened, frizzled class receptor involved_in IEA
ISO		 GO_REF:0000107
(MGI:5142377|PMID:11517919)
(PMID:11517919)		 Ensembl
RGD		 PMID:11517919 GO_REF:0000107 MGI:5142377 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20134
    developmental process 7034
      anatomical structure development 6553
        ventral midline development 5
          floor plate formation 3
          ventral midline determination 1
Path 2
Term Annotations click to browse term
  biological_process 20134
    developmental process 7034
      anatomical structure development 6553
        multicellular organism development 5285
          system development 4565
            nervous system development 2825
              central nervous system development 1212
                ventral midline development 5
                  floor plate formation 3
                  ventral midline determination 1
paths to the root