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ONTOLOGY REPORT - ANNOTATIONS

Term:fusion of sperm to egg plasma membrane involved in single fertilization
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Accession:GO:0007342 term browser browse the term
Definition:The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head.
Synonyms:narrow_synonym: sperm-oocyte fusion

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fusion of sperm to egg plasma membrane involved in single fertilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Catsper1 cation channel sperm associated 1 acts_upstream_of_or_within ISO (PMID:11595941) MGI PMID:11595941 NCBI chrNW_004955422:19,315,640...19,322,868 JBrowse link
G Cd9 CD9 molecule involved_in ISO (PMID:14575715)
(MGI:1351540|PMID:10634790), (MGI:1351541|PMID:10634791), (MGI:1353864|PMID:10700183), (MGI:5056242|PMID:21690351)		 UniProt PMID:10634790 PMID:10634791 PMID:10700183 PMID:14575715 PMID:21690351 MGI:1351540 MGI:1351541 MGI:1353864 MGI:5056242 NCBI chrNW_004955413:3,891,874...3,924,065
Ensembl chrNW_004955413:3,891,874...3,928,119 		JBrowse link
G CUNH16orf92 chromosome unknown C16orf92 homolog involved_in ISO (MGI:6415482|PMID:32295885) UniProt PMID:32295885 MGI:6415482 NCBI chrNW_004955493:6,940,226...6,941,290
Ensembl chrNW_004955493:6,940,226...6,941,290 		JBrowse link
G Dcst1 DC-STAMP domain containing 1 involved_in ISO (MGI:6694748|PMID:33871360) UniProt PMID:33871360 MGI:6694748 NCBI chrNW_004955545:1,529,926...1,545,459
Ensembl chrNW_004955545:1,530,062...1,545,139 		JBrowse link
G Dcst2 DC-STAMP domain containing 2 involved_in ISO (MGI:6694748|PMID:33871360) UniProt PMID:33871360 MGI:6694748 NCBI chrNW_004955545:1,518,917...1,529,865
Ensembl chrNW_004955545:1,523,100...1,529,865 		JBrowse link
G Eqtn equatorin acts_upstream_of_or_within ISO (PMID:9674989) MGI PMID:9674989 NCBI chrNW_004955472:7,554,243...7,563,620 JBrowse link
G Frey1 Frey regulator of sperm-oocyte fusion 1 involved_in ISO (MGI:7332329|PMID:35960805), (MGI:7338896|PMID:36050562), (PMID:35960805) UniProt PMID:35960805 PMID:36050562 MGI:7332329 MGI:7338896 NCBI chrNW_004955422:2,063,253...2,063,942 JBrowse link
G Glipr1l1 GLIPR1 like 1 involved_in ISO (MGI:6436237|PMID:31672133), (PMID:31672133) UniProt PMID:31672133 MGI:6436237 NCBI chrNW_004955405:14,710,789...14,755,709
Ensembl chrNW_004955405:14,710,431...14,755,826 		JBrowse link
G Itga3 integrin subunit alpha 3 NOT|acts_upstream_of_or_within ISO (PMID:12591243) MGI PMID:12591243 NCBI chrNW_004955451:11,563,120...11,590,119
Ensembl chrNW_004955451:11,561,704...11,589,727 		JBrowse link
G Izumo1 izumo sperm-oocyte fusion 1 involved_in ISO (PMID:15759005)
(MGI:5568137|PMID:24739963), (MGI:6436237|PMID:31672133), (MGI:7332329|PMID:35960805), (PMID:24739963)
(MGI:3575846|PMID:15759005)		 HGNC-UCL
UniProt		 PMID:15759005 PMID:24739963 PMID:31672133 PMID:35960805 MGI:3575846 MGI:5568137 MGI:6436237 MGI:7332329 NCBI chrNW_004955559:1,825,589...1,830,535 JBrowse link
G Izumo1r IZUMO1 receptor, JUNO involved_in ISO (MGI:5568137|PMID:24739963)
(MGI:5896483|PMID:27416963), (PMID:24739963)		 UniProt PMID:24739963 PMID:27416963 MGI:5568137 MGI:5896483 NCBI chrNW_004955414:283,646...287,422
Ensembl chrNW_004955414:283,630...287,433 		JBrowse link
G Llcfc1 LLLL and CFNLAS motif containing 1 involved_in ISO (MGI:6431603|PMID:32393636) UniProt PMID:32393636 MGI:6431603 NCBI chrNW_004955494:688,212...689,634 JBrowse link
G Lyzl6 lysozyme like 6 involved_in ISO (PMID:24013621) UniProt PMID:24013621 NCBI chrNW_004955481:225,132...273,565
Ensembl chrNW_004955481:223,484...237,975 		JBrowse link
G Spaca3 sperm acrosome associated 3 involved_in ISO (PMID:15982649)
(MGI:3588938|PMID:15982649)		 UniProt PMID:15982649 MGI:3588938 NCBI chrNW_004955481:7,832,518...7,840,130
Ensembl chrNW_004955481:7,836,097...7,840,189 		JBrowse link
G Spata46 spermatogenesis associated 46 involved_in ISO (MGI:5806174|PMID:27488028) UniProt PMID:27488028 MGI:5806174 NCBI chrNW_004955462:13,950,726...13,953,765
Ensembl chrNW_004955462:13,951,172...13,953,694 		JBrowse link
G Spesp1 sperm equatorial segment protein 1 acts_upstream_of_or_within ISO (PMID:20375058) MGI PMID:20375058 NCBI chrNW_004955450:7,355,144...7,370,413
Ensembl chrNW_004955450:7,355,082...7,370,735 		JBrowse link
G Sppl2c signal peptide peptidase like 2C involved_in ISO (PMID:35960805) UniProt PMID:35960805 NCBI chrNW_004955478:10,368,379...10,370,624
Ensembl chrNW_004955478:10,365,857...10,370,548 		JBrowse link
G Tmem95 transmembrane protein 95 involved_in ISO (MGI:6431603|PMID:32393636), (MGI:6436438|PMID:32484434) UniProt PMID:32393636 PMID:32484434 MGI:6431603 MGI:6436438 NCBI chrNW_004955467:9,562,723...9,564,818
Ensembl chrNW_004955467:9,562,723...9,564,818 		JBrowse link
G Tpst2 tyrosylprotein sulfotransferase 2 acts_upstream_of_or_within ISO (PMID:21339297) MGI PMID:21339297 NCBI chrNW_004955455:1,106,403...1,128,455
Ensembl chrNW_004955455:1,106,294...1,129,196 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    cellular process 11480
      cellular process involved in reproduction in multicellular organism 413
        fusion of sperm to egg plasma membrane involved in single fertilization 19
          negative regulation of fusion of sperm to egg plasma membrane 0
          regulation of fusion of sperm to egg plasma membrane + 0
Path 2
Term Annotations click to browse term
  biological_process 12346
    cellular process 11480
      cellular component organization or biogenesis 5364
        cellular component organization 5235
          endomembrane system organization 460
            plasma membrane organization 131
              plasma membrane fusion 21
                fusion of sperm to egg plasma membrane involved in single fertilization 19
                  negative regulation of fusion of sperm to egg plasma membrane 0
                  regulation of fusion of sperm to egg plasma membrane + 0
paths to the root