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ONTOLOGY REPORT - ANNOTATIONS

Term:JNK cascade
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Accession:GO:0007254 term browser browse the term
Definition:A MAPK cascade containing at least the JNK (MAPK8) MAP kinase. It starts with the activation of JUN3K (a MAPK3K), which activates JNKK a MAP2K), which in turn activates JNK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. The JNK cascade is activated by stress signals, as well as by G protein-coupled receptors, growth factors, and cytokines, and results in cellular responses such as cell proliferation, cell differentiation, apoptosis and inflammation.
Synonyms:exact_synonym: c-Jun N-terminal kinase cascade
 narrow_synonym: JNK1 cascade;   JNK2 cascade;   JNK3 cascade;   MAPK10 cascade;   MAPK8 cascade;   MAPK9 cascade
 broad_synonym: SAPK cascade;   stress-activated protein kinase cascade
 xref: Reactome:R-HSA-450321 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"


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JNK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in ISO MGI:3720850 (PMID:18802055), (PMID:21533046) RGD PMID:18802055 PMID:21533046 NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Becn1 beclin 1 IMP RGD PMID:27769861 RGD:329853763 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Card9 caspase recruitment domain family, member 9 acts_upstream_of ISO
IEA 		MGI:3698412 (PMID:17187069)
GO_REF:0000107 		RGD
Ensembl		 PMID:17187069 GO_REF:0000107 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Casr calcium-sensing receptor IMP RGD PMID:15084499 RGD:1358486 NCBI chr11:77,738,398...77,813,639
Ensembl chr11:64,235,251...64,304,811 		JBrowse link
G Cdc42ep5 CDC42 effector protein 5 acts_upstream_of_or_within ISO (PMID:10490598) RGD PMID:10490598 NCBI chr 1:70,035,921...70,038,990 JBrowse link
G Daxx death-domain associated protein involved_in ISO
IEA 		(PMID:9215629)
GO_REF:0000107 		RGD
Ensembl		 PMID:9215629 GO_REF:0000107 NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Dusp19 dual specificity phosphatase 19 acts_upstream_of_or_within ISO (PMID:11959862) RGD PMID:11959862 NCBI chr 3:85,945,289...86,081,289
Ensembl chr 3:65,538,420...65,553,534 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor acts_upstream_of_or_within ISO
IEA 		MGI:1932102 (PMID:16319174)
GO_REF:0000107 		RGD
Ensembl		 PMID:16319174 GO_REF:0000107 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Fgf12 fibroblast growth factor 12 acts_upstream_of_or_within ISO UniProtKB:Q9ERE9 (PMID:12815063) RGD PMID:12815063 NCBI chr11:85,501,947...86,069,543
Ensembl chr11:71,997,099...72,562,607 		JBrowse link
G Fgf14 fibroblast growth factor 14 acts_upstream_of_or_within ISO UniProtKB:Q9ERE9 (PMID:12815063) RGD PMID:12815063 NCBI chr15:107,442,800...108,086,486
Ensembl chr15:101,045,036...101,679,900 		JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 acts_upstream_of_or_within ISO
IEA 		(PMID:10747961)
GO_REF:0000107 		RGD
Ensembl		 PMID:10747961 GO_REF:0000107 NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507 		JBrowse link
G Il1b interleukin 1 beta acts_upstream_of ISO
IEA 		MGI:1346877 (PMID:16260493)
GO_REF:0000107 		RGD
Ensembl		 PMID:16260493 GO_REF:0000107 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il3 interleukin 3 acts_upstream_of ISO (PMID:14967141) RGD PMID:14967141 NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 IMP RGD PMID:15890643 RGD:1579817 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 IMP RGD PMID:15890643 RGD:1579817 NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO
IEA 		(PMID:19302196)
GO_REF:0000107 		RGD
Ensembl		 PMID:19302196 GO_REF:0000107 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Maged1 MAGE family member D1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:59,422,715...59,429,381
Ensembl chr  X:59,422,717...59,429,364 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha IMP RGD PMID:27769861 RGD:329853763 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 IDA RGD PMID:17064355 RGD:2298577 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in IDA
ISO
IEA 		(PMID:11959862)
GO_REF:0000107 		RGD
Ensembl		 PMID:11959862 PMID:10051439 PMID:17064355 PMID:15680699 PMID:11849756 GO_REF:0000107, RGD:2298561, RGD:2298577, RGD:2298567, RGD:2298565 NCBI chr12:7,389,032...7,398,377
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 acts_upstream_of_or_within ISO (PMID:14967141) RGD PMID:14967141 NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 involved_in IDA
IEA
IBA
ISO 		GO_REF:0000107
GO_REF:0000033
(PMID:15258589) 		Ensembl
GO_Central
RGD		 PMID:15258589 PMID:15680699 PMID:17064355 GO_REF:0000033 GO_REF:0000107, RGD:2298567, RGD:2298577 NCBI chr 1:212,404,685...212,417,986
Ensembl chr 1:202,975,353...202,988,652 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 involved_in IEA
IBA
ISO 		GO_REF:0000107
GO_REF:0000033
(PMID:27511108)
GO_REF:0000002 		Ensembl
GO_Central
RGD
InterPro		 PMID:27511108 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:135,507,082...135,527,396
Ensembl chr 7:133,630,835...133,640,789 		JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 involved_in ISO
IEA
IBA 		(PMID:11726277), (PMID:9353328)
GO_REF:0000107
GO_REF:0000002
(PMID:27511108)
GO_REF:0000033 		RGD
Ensembl
InterPro
GO_Central		 PMID:9353328 PMID:11726277 PMID:27511108 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr11:92,596,436...92,741,717
Ensembl chr11:79,097,247...79,235,181 		JBrowse link
G Map3k15 mitogen-activated protein kinase kinase kinase 15 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:34,713,150...34,859,054
Ensembl chr  X:34,713,175...34,858,807 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:27598200)
(PMID:11836244), (PMID:12220515), (PMID:14521931), (PMID:15737997), (PMID:32610081) 		UniProt
Ensembl
RGD		 PMID:11836244 PMID:12220515 PMID:14521931 PMID:15737997 PMID:27598200 More... GO_REF:0000024 GO_REF:0000107 NCBI chr 3:77,538,146...77,697,540
Ensembl chr 3:57,130,551...57,289,626 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in IDA
IEA
IBA
ISO 		GO_REF:0000107
GO_REF:0000033
(PMID:11959862), (PMID:21771788), (PMID:22095282) 		Ensembl
GO_Central
RGD		 PMID:11959862 PMID:21771788 PMID:22095282 PMID:12524169 GO_REF:0000033 GO_REF:0000107, RGD:2298708 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:150,724,029...150,736,113
Ensembl chr 5:145,440,346...145,452,212 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in
acts_upstream_of 		ISO
IEA
IBA
ISS 		(PMID:9079627)
GO_REF:0000107
(PMID:29291351)
MGI:104798|MGI:96536|MGI:96824 (PMID:16260493)
GO_REF:0000033
GO_REF:0000024 		RGD
Ensembl
GO_Central
UniProt		 PMID:9079627 PMID:16260493 PMID:29291351 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 involved_in ISO
IEA 		(PMID:8824585)
GO_REF:0000107 		RGD
Ensembl		 PMID:8824585 GO_REF:0000107 NCBI chr 1:93,398,460...93,419,996
Ensembl chr 1:84,271,069...84,292,493 		JBrowse link
G Mapk10 mitogen activated protein kinase 10 involved_in IDA
IBA
ISO
IEA
ISS 		GO_REF:0000033
(PMID:9349820)
GO_REF:0000108
GO_REF:0000024 		GO_Central
RGD
GOC
UniProt		 PMID:9349820 PMID:10051439 PMID:15680699 GO_REF:0000024 GO_REF:0000033 GO_REF:0000108, RGD:2298561, RGD:2298567 NCBI chr14:6,802,247...7,094,103
Ensembl chr14:6,497,707...6,786,201 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISO
IEA
IBA
ISS 		(PMID:8654373)
GO_REF:0000107
GO_REF:0000033
(PMID:10811224)
GO_REF:0000108
GO_REF:0000024 		RGD
Ensembl
GO_Central
GOC
UniProt		 PMID:8654373 PMID:10811224 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000108 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:78,355,048...78,372,884 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:10827199) 		GO_Central
Ensembl
RGD		 PMID:10827199 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:122,406,350...122,416,602
Ensembl chr 7:120,526,732...120,536,982 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 acts_upstream_of_or_within ISO
IEA 		(PMID:10629060)
GO_REF:0000107 		RGD
Ensembl		 PMID:10629060 GO_REF:0000107 NCBI chr10:14,422,936...14,463,387
Ensembl chr10:13,918,400...13,958,273 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 involved_in IDA
IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000108
GO_REF:0000107
(PMID:8654373) 		GO_Central
GOC
Ensembl
RGD		 PMID:8654373 PMID:10051439 GO_REF:0000033 GO_REF:0000107 GO_REF:0000108, RGD:2298561 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of IMP
IEA
ISO 		GO_REF:0000107
MGI:2385681 (PMID:12855817) 		Ensembl
RGD		 PMID:12855817 PMID:15890643 GO_REF:0000107, RGD:1579817 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:18802055) 		Ensembl
RGD		 PMID:18802055 GO_REF:0000107 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of ISO
IEA 		(PMID:18261938)
GO_REF:0000107 		RGD
Ensembl		 PMID:18261938 GO_REF:0000107 NCBI chr 4:85,391,142...85,442,281
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of ISO (PMID:18261938) RGD PMID:18261938 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Nox1 NADPH oxidase 1 acts_upstream_of ISO
IEA 		MGI:3616995 (PMID:19661248)
GO_REF:0000107 		RGD
Ensembl		 PMID:19661248 GO_REF:0000107 NCBI chr  X:101,572,338...101,625,571
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin acts_upstream_of_or_within ISO (PMID:11562357) RGD PMID:11562357 NCBI chr 1:94,848,261...94,876,522
Ensembl chr 1:85,720,812...85,749,078 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 acts_upstream_of ISO
IEA 		MGI:1100089 (PMID:22073305)
GO_REF:0000107 		RGD
Ensembl		 PMID:22073305 GO_REF:0000107 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
G Ptger4 prostaglandin E receptor 4 involved_in IDA PMID:19233324 UniProt PMID:19233324 RGD:8554254 NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Ptk2 protein tyrosine kinase 2 IMP RGD PMID:12782622 RGD:2292618 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of
involved_in 		ISO
IEA
IBA 		MGI:2446070|MGI:2660793 (PMID:11894097), (PMID:11894098), (PMID:18261938)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:11894097 PMID:11894098 PMID:18261938 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 acts_upstream_of_or_within ISO (PMID:12839624) RGD PMID:12839624 NCBI chr17:12,124,749...12,300,044
Ensembl chr17:11,972,830...12,148,152 		JBrowse link
G Sh3bp5 SH3-domain binding protein 5 NAS RGD PMID:12167088 RGD:737651 NCBI chr16:6,589,877...6,676,524
Ensembl chr16:6,583,465...6,698,975 		JBrowse link
G Smad3 SMAD family member 3 involved_in ISO
IEA 		(PMID:18802055)
GO_REF:0000107 		RGD
Ensembl		 PMID:18802055 GO_REF:0000107 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Stk3 serine/threonine kinase 3 acts_upstream_of ISO MGI:104798|MGI:1929004 (PMID:20080598) RGD PMID:20080598 NCBI chr 7:67,938,341...68,208,472
Ensembl chr 7:66,052,345...66,323,233 		JBrowse link
G Stradb STE20 related adaptor beta acts_upstream_of_or_within ISO
IEA 		(PMID:12574163)
GO_REF:0000107 		RGD
Ensembl		 PMID:12574163 GO_REF:0000107 NCBI chr 9:60,414,182...60,433,084
Ensembl chr 9:60,414,182...60,433,084 		JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of
involved_in 		ISO
IEA 		(PMID:16260493)
GO_REF:0000107
(PMID:18802055) 		RGD
Ensembl		 PMID:16260493 PMID:18802055 GO_REF:0000107 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of ISO
IEA 		MGI:1346877 (PMID:16260493), (PMID:18261938)
GO_REF:0000107 		RGD
Ensembl		 PMID:16260493 PMID:18261938 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr7 toll-like receptor 7 involved_in ISO
IEA 		(PMID:18802055)
GO_REF:0000107 		RGD
Ensembl		 PMID:18802055 GO_REF:0000107 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of
acts_upstream_of_or_within 		ISO MGI:1346877 (PMID:16260493), (PMID:20080598)
MGI:1341850 (PMID:17015619) 		RGD PMID:16260493 PMID:17015619 PMID:20080598 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of ISO
IEA 		MGI:109520 (PMID:22073305)
GO_REF:0000107 		RGD
Ensembl		 PMID:22073305 GO_REF:0000107 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Traf6 TNF receptor associated factor 6 IMP RGD PMID:15890643 RGD:1579817 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 7:93,096,001...93,102,547
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO
IEA 		(PMID:12839624)
GO_REF:0000107 		RGD
Ensembl		 PMID:12839624 GO_REF:0000107 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
JUN phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk10 mitogen activated protein kinase 10 IDA RGD PMID:10597270 RGD:7495842 NCBI chr14:6,802,247...7,094,103
Ensembl chr14:6,497,707...6,786,201 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 acts_upstream_of_or_within
involved_in 		ISO (PMID:14967141)
MGI:2384141 (PMID:14967141)
(PMID:21095239) 		RGD PMID:14967141 PMID:21095239 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 acts_upstream_of_or_within ISO (PMID:9235893) RGD PMID:9235893 NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:78,355,048...78,372,884 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:16942465 RGD:2304233 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
negative regulation of JNK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aida axin interactor, dorsalization associated involved_in ISO
IEA 		UniProtKB:O35625 (PMID:17681137)
GO_REF:0000107 		RGD
Ensembl		 PMID:17681137 GO_REF:0000107 NCBI chr13:94,940,311...94,967,920
Ensembl chr13:94,939,741...94,967,920 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 IDA RGD PMID:17064355 RGD:2298577 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase involved_in ISO
IEA
IBA
ISS 		(PMID:29291351)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024 		RGD
Ensembl
GO_Central
UniProt		 PMID:29291351 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr19:34,487,491...34,547,311
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Cyld-ps1 CYLD lysine 63 deubiquitinase, pseudogene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:15,202,074...15,205,290
Ensembl chr 5:15,202,251...15,205,291 		JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 involved_in ISO
IBA 		(PMID:17197390)
GO_REF:0000033 		RGD
GO_Central		 PMID:17197390 GO_REF:0000033 NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906 		JBrowse link
G Dusp10 dual specificity phosphatase 10 involved_in
acts_upstream_of_or_within 		ISO
IEA
IBA 		(PMID:10391943)
GO_REF:0000107
GO_REF:0000033
MGI:3052343 (PMID:15306813) 		RGD
Ensembl
GO_Central		 PMID:10391943 PMID:15306813 GO_REF:0000033 GO_REF:0000107 NCBI chr13:98,145,317...98,183,304
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Dusp19 dual specificity phosphatase 19 involved_in ISO (PMID:11959862) RGD PMID:11959862 NCBI chr 3:85,945,289...86,081,289
Ensembl chr 3:65,538,420...65,553,534 		JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in ISO
IBA 		(PMID:11085983), (PMID:19010898)
GO_REF:0000033 		RGD
GO_Central		 PMID:11085983 PMID:19010898 GO_REF:0000033 NCBI chr10:87,420,213...87,434,202
Ensembl chr10:86,920,014...86,933,962 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA 		(PMID:19781631)
GO_REF:0000107 		RGD
Ensembl		 PMID:19781631 GO_REF:0000107 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fktn fukutin involved_in ISO (PMID:18808525) RGD PMID:18808525 NCBI chr 5:73,134,746...73,191,772
Ensembl chr 5:68,340,028...68,396,409 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO
IEA 		(PMID:11931768)
GO_REF:0000107
(PMID:22424771) 		RGD
Ensembl		 PMID:11931768 PMID:22424771 GO_REF:0000107 NCBI chr10:55,136,043...55,139,106
Ensembl chr10:54,637,455...54,640,650 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:16636664) 		Ensembl
RGD		 PMID:16636664 GO_REF:0000107 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hdac3 histone deacetylase 3 involved_in ISO
IEA 		(PMID:11931768)
GO_REF:0000107 		RGD
Ensembl		 PMID:11931768 GO_REF:0000107 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Itch itchy E3 ubiquitin protein ligase involved_in ISO
IEA 		(PMID:18246070)
GO_REF:0000107 		RGD
Ensembl		 PMID:18246070 GO_REF:0000107 NCBI chr 3:164,102,490...164,193,932
Ensembl chr 3:143,645,637...143,733,543 		JBrowse link
G Klhl31 kelch-like family member 31 involved_in ISO
IEA
IBA 		(PMID:18719355)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:18719355 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:78,515,514...78,538,873
Ensembl chr 8:78,515,514...78,538,873 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 IMP RGD PMID:12064607 RGD:1299562 NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:78,355,048...78,372,884 		JBrowse link
G Marveld3 MARVEL domain containing 3 acts_upstream_of_or_within ISO (PMID:24567356) RGD PMID:24567356 NCBI chr19:54,818,180...54,832,871
Ensembl chr19:37,905,638...37,923,420 		JBrowse link
G Mecom MDS1 and EVI1 complex locus involved_in ISO (PMID:10856240) RGD PMID:10856240 NCBI chr 2:114,837,815...115,393,052
Ensembl chr 2:112,909,321...113,464,590 		JBrowse link
G Men1 menin 1 involved_in ISO
IEA 		(PMID:12226747)
GO_REF:0000107 		RGD
Ensembl		 PMID:12226747 GO_REF:0000107 NCBI chr 1:213,068,166...213,074,132
Ensembl chr 1:203,639,000...203,644,871 		JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in ISO (PMID:11931768) RGD PMID:11931768 NCBI chr10:47,498,852...47,641,612
Ensembl chr10:46,999,536...47,141,032 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 acts_upstream_of_or_within ISO
IEA 		MGI:1100089 (PMID:22073305)
GO_REF:0000107 		RGD
Ensembl		 PMID:22073305 GO_REF:0000107 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
G Per1 period circadian regulator 1 involved_in IMP PMID:24447840 UniProt PMID:24447840 RGD:8655527 NCBI chr10:54,299,002...54,313,804
Ensembl chr10:53,805,535...53,814,431 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS GO_REF:0000024 ParkinsonsUK-UCL GO_REF:0000024 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 involved_in ISO
IEA
ISS 		(PMID:22095282)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:22095282 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:104,595,339...104,605,552
Ensembl chr 1:95,458,850...95,468,345 		JBrowse link
G Sfrp4 secreted frizzled-related protein 4 IDA RGD PMID:18567805 RGD:4107045 NCBI chr17:45,278,867...45,330,806
Ensembl chr17:45,234,097...45,330,736 		JBrowse link
G Sh3rf2 SH3 domain containing ring finger 2 involved_in IMP PMID:22128169 UniProt PMID:22128169 RGD:13673844 NCBI chr18:34,296,753...34,397,880
Ensembl chr18:34,046,879...34,146,856 		JBrowse link
G Sirpa signal-regulatory protein alpha involved_in ISO (PMID:17954568) RGD PMID:17954568 NCBI chr 3:137,272,932...137,311,279
Ensembl chr 3:116,819,726...116,858,098 		JBrowse link
G Taok3 TAO kinase 3 involved_in ISO
IEA 		(PMID:10559204)
GO_REF:0000107 		RGD
Ensembl		 PMID:10559204 GO_REF:0000107 NCBI chr12:44,973,180...45,134,439
Ensembl chr12:39,314,027...39,461,244 		JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in ISO (PMID:17452330) RGD PMID:17452330 NCBI chr 7:93,096,001...93,102,547
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Zmynd11 zinc finger, MYND-type containing 11 involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr17:60,542,669...60,631,913
Ensembl chr17:60,543,077...60,631,902 		JBrowse link
negative regulation of JUN kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aida axin interactor, dorsalization associated acts_upstream_of_or_within ISO (PMID:17681137) RGD PMID:17681137 NCBI chr13:94,940,311...94,967,920
Ensembl chr13:94,939,741...94,967,920 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:24512202) 		UniProt
RGD		 PMID:24512202 GO_REF:0000024 NCBI chr 5:60,638,404...60,649,315
Ensembl chr 5:55,842,426...55,853,967 		JBrowse link
G Dusp10 dual specificity phosphatase 10 acts_upstream_of_or_within ISO MGI:3052343 (PMID:15306813) RGD PMID:15306813 NCBI chr13:98,145,317...98,183,304
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Dusp19 dual specificity phosphatase 19 involved_in ISO (PMID:11959862) RGD PMID:11959862 NCBI chr 3:85,945,289...86,081,289
Ensembl chr 3:65,538,420...65,553,534 		JBrowse link
G Hipk3 homeodomain interacting protein kinase 3 involved_in ISO (PMID:11034606) RGD PMID:11034606 NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 involved_in IMP PMID:21076496 RGD
UniProt		 PMID:12064607 PMID:21076496 RGD:1299562, RGD:13673827 NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:78,355,048...78,372,884 		JBrowse link
G Nppa natriuretic peptide A involved_in ISO (PMID:22399583) RGD PMID:22399583 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Pdcd4 programmed cell death 4 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:252,921,392...252,944,275 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23991106) RGD PMID:23991106 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Serpinb3 serpin family B member 3 involved_in ISO (PMID:21383048) RGD PMID:21383048 NCBI chr13:23,274,120...23,280,660
Ensembl chr13:23,274,484...23,313,682 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of_or_within ISO MGI:108078|MGI:1860298 (PMID:19300477) RGD PMID:19300477 NCBI chr16:75,278,325...75,316,736
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO MGI:1860298|MGI:892014 (PMID:19300477) RGD PMID:19300477 NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Sfrp5 secreted frizzled-related protein 5 acts_upstream_of_or_within ISO MGI:108078|MGI:892014 (PMID:19300477) RGD PMID:19300477 NCBI chr 1:241,006,762...241,011,224
Ensembl chr 1:241,006,762...241,011,224 		JBrowse link
positive regulation of JNK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in ISO
IEA 		ComplexPortal:CPX-1134|UniProtKB:P10749 (PMID:20739563)
GO_REF:0000107 		RGD
Ensembl		 PMID:20739563 GO_REF:0000107 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Ankrd6 ankyrin repeat domain 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:47,197,981...47,343,183
Ensembl chr 5:47,202,873...47,343,090 		JBrowse link
G App amyloid beta precursor protein involved_in ISO
IEA 		ComplexPortal:CPX-1134 (PMID:23921129)
GO_REF:0000107 		RGD
Ensembl		 PMID:23921129 GO_REF:0000107 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Axin1 axin 1 involved_in
acts_upstream_of_or_within 		ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
MGI:1856035 (PMID:18316368)
(PMID:17681137) 		UniProt
Ensembl
RGD		 PMID:17681137 PMID:18316368 GO_REF:0000024 GO_REF:0000107 NCBI chr10:15,667,894...15,720,092
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 involved_in ISO
IEA 		(PMID:11865055)
GO_REF:0000107 		RGD
Ensembl		 PMID:11865055 GO_REF:0000107 NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606 		JBrowse link
G Card9 caspase recruitment domain family, member 9 acts_upstream_of_or_within ISO
IEA 		(PMID:17187069)
MGI:3698412 (PMID:17187069)
GO_REF:0000107 		RGD
Ensembl		 PMID:17187069 GO_REF:0000107 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Ccdc88c coiled-coil domain containing 88C acts_upstream_of_or_within_positive_effect ISO
IEA 		(PMID:25062847)
GO_REF:0000107 		RGD
Ensembl		 PMID:25062847 GO_REF:0000107 NCBI chr 6:125,899,337...126,019,162
Ensembl chr 6:120,169,738...120,289,555 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:15778365) RGD PMID:15778365 NCBI chr 5:61,759,220...61,761,164
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl21 C-C motif chemokine ligand 21 involved_in ISO
IEA 		(PMID:15778365)
GO_REF:0000107 		RGD
Ensembl		 PMID:15778365 GO_REF:0000107 NCBI chr 5:61,776,411...61,777,515
Ensembl chr 5:56,980,558...56,981,686 		JBrowse link
G Ccn2 cellular communication network factor 2 involved_in ISO
IEA 		(PMID:20008146)
GO_REF:0000107 		RGD
Ensembl		 PMID:20008146 GO_REF:0000107 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Cd27 CD27 molecule involved_in ISO (PMID:9692890) RGD PMID:9692890 NCBI chr 4:159,716,932...159,721,823
Ensembl chr 4:158,030,703...158,035,592 		JBrowse link
G Cdc42 cell division cycle 42 IDA RGD PMID:17161586 RGD:2298583 NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Cracr2a calcium release activated channel regulator 2A involved_in ISO (PMID:27016526) RGD PMID:27016526 NCBI chr 4:162,094,247...162,207,926
Ensembl chr 4:160,408,077...160,518,107 		JBrowse link
G Crk CRK proto-oncogene, adaptor protein IMP RGD PMID:12198159 RGD:1298803 NCBI chr10:61,028,736...61,054,971
Ensembl chr10:60,530,464...60,553,406 		JBrowse link
G Dab2 DAB adaptor protein 2 involved_in ISO (PMID:15894542) RGD PMID:15894542 NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:12813029), (PMID:15310755), (PMID:17389591), (PMID:19903888) 		UniProt
Ensembl
RGD		 PMID:12813029 PMID:15310755 PMID:17389591 PMID:19903888 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Dixdc1 DIX domain containing 1 IMP RGD PMID:19339625 RGD:2308917 NCBI chr 8:51,007,835...51,081,191
Ensembl chr 8:51,007,838...51,081,090 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:23164821) RGD PMID:23164821 NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Dusp19 dual specificity phosphatase 19 involved_in ISO (PMID:11959862) RGD PMID:11959862 NCBI chr 3:85,945,289...86,081,289
Ensembl chr 3:65,538,420...65,553,534 		JBrowse link
G Dusp22 dual specificity phosphatase 22 acts_upstream_of_or_within
involved_in 		ISO
IBA 		(PMID:12138158)
GO_REF:0000033 		RGD
GO_Central		 PMID:12138158 GO_REF:0000033 NCBI chr17:33,989,637...34,040,021
Ensembl chr17:33,780,981...33,831,321 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:17593335), (PMID:19137009) 		Ensembl
RGD		 PMID:17593335 PMID:19137009 GO_REF:0000107 NCBI chr10:55,222,245...55,231,506
Ensembl chr10:54,723,411...54,732,820 		JBrowse link
G Dvl3 dishevelled segment polarity protein 3 involved_in ISO
IEA 		(PMID:19137009)
GO_REF:0000107 		RGD
Ensembl		 PMID:19137009 GO_REF:0000107 NCBI chr11:93,869,834...93,887,013
Ensembl chr11:80,366,117...80,382,462 		JBrowse link
G Eda2r ectodysplasin A2 receptor involved_in ISO
IBA
IEA 		(PMID:12270937)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002 		RGD
GO_Central
Ensembl
InterPro		 PMID:12270937 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:62,224,763...62,269,333
Ensembl chr  X:62,228,229...62,269,268 		JBrowse link
G Edar ectodysplasin-A receptor involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr20:26,587,836...26,666,543
Ensembl chr20:26,587,839...26,666,494 		JBrowse link
G Edn1 endothelin 1 involved_in ISO
IEA 		(PMID:12847114)
GO_REF:0000107 		RGD
Ensembl		 PMID:12847114 GO_REF:0000107 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Epha4 Eph receptor A4 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 9:86,263,982...86,406,744
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA 		(PMID:11413129)
GO_REF:0000107 		RGD
Ensembl		 PMID:11413129 GO_REF:0000107 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fcgr2b Fc gamma receptor 2B involved_in ISO (PMID:23921129) RGD PMID:23921129 NCBI chr13:85,725,897...85,740,517
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 IMP RGD PMID:9668039 RGD:1299389 NCBI chr11:84,399,989...84,551,013
Ensembl chr11:84,399,816...84,546,972 		JBrowse link
G Fgf19 fibroblast growth factor 19 involved_in ISO
IEA 		(PMID:12815072)
GO_REF:0000107 		RGD
Ensembl		 PMID:12815072 GO_REF:0000107 NCBI chr 1:209,485,813...209,490,267
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 involved_in ISO
IEA 		(PMID:16076871)
GO_REF:0000107 		RGD
Ensembl		 PMID:16076871 GO_REF:0000107 NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770 		JBrowse link
G Fzd10 frizzled class receptor 10 involved_in ISO (PMID:19137009) RGD PMID:19137009 NCBI chr12:28,098,371...28,101,566
Ensembl chr12:28,098,371...28,101,566 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha involved_in ISO
IEA 		(PMID:9827804)
GO_REF:0000107 		RGD
Ensembl		 PMID:9827804 GO_REF:0000107 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta involved_in ISO
IEA 		(PMID:9827804)
GO_REF:0000107 		RGD
Ensembl		 PMID:9827804 GO_REF:0000107 NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma involved_in ISO
IEA 		(PMID:9827804)
GO_REF:0000107 		RGD
Ensembl		 PMID:9827804 GO_REF:0000107 NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:14678985) RGD PMID:14678985 NCBI chr 4:68,399,358...68,586,404
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:12765338) RGD PMID:12765338 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hras HRas proto-oncogene, GTPase involved_in ISO (PMID:22065586) RGD PMID:22065586 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:15671867 RGD:1358666 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta acts_upstream_of_or_within
involved_in 		IDA
ISO
IEA 		MGI:1346877 (PMID:16260493)
ComplexPortal:CPX-1134|UniProtKB:Q15109 (PMID:20739563)
GO_REF:0000107 		RGD
Ensembl		 PMID:16260493 PMID:20739563 PMID:15671867 GO_REF:0000107, RGD:1358666 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (PMID:14967141) RGD PMID:14967141 NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Ltbr lymphotoxin beta receptor involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr 4:159,795,115...159,801,571
Ensembl chr 4:158,108,886...158,121,539 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 IDA RGD PMID:17064355 RGD:2298577 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in IDA
IEA
ISO 		GO_REF:0000107
(PMID:9405446) 		Ensembl
RGD		 PMID:9405446 PMID:10051439 PMID:11849756 PMID:17064355 GO_REF:0000107, RGD:2298561, RGD:2298565, RGD:2298577 NCBI chr12:7,389,032...7,398,377
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IDA RGD PMID:9110999 RGD:2293488 NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 involved_in ISO
IEA 		(PMID:17584736)
GO_REF:0000107 		RGD
Ensembl		 PMID:17584736 GO_REF:0000107 NCBI chr 1:92,083,376...92,101,676
Ensembl chr 1:82,955,207...82,974,084 		JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 involved_in IDA
ISO
IEA 		(PMID:17584736)
GO_REF:0000107 		RGD
Ensembl		 PMID:17584736 PMID:17064355 GO_REF:0000107, RGD:2298577 NCBI chr 1:212,404,685...212,417,986
Ensembl chr 1:202,975,353...202,988,652 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO
IEA 		(PMID:12050113)
GO_REF:0000107 		RGD
Ensembl		 PMID:12050113 GO_REF:0000107 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO MGI:104798|MGI:96536|MGI:96824 (PMID:16260493) RGD PMID:16260493 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 involved_in ISO (PMID:17584736) RGD PMID:17584736 NCBI chr 1:213,074,360...213,090,042
Ensembl chr 1:203,645,153...203,660,331 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 involved_in ISO (PMID:9135144) RGD PMID:9135144 NCBI chr 9:49,696,573...49,822,353
Ensembl chr 9:42,200,278...42,326,698 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:23963642) 		UniProt
Ensembl
RGD		 PMID:23963642 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:78,355,048...78,372,884 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 involved_in IMP PMID:21076496 UniProt PMID:21076496 RGD:13673827 NCBI chr10:14,422,936...14,463,387
Ensembl chr10:13,918,400...13,958,273 		JBrowse link
G Mapkbp1 mitogen activated protein kinase binding protein 1 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:10471813) 		GO_Central
RGD		 PMID:10471813 GO_REF:0000033 NCBI chr 3:106,947,342...106,998,368
Ensembl chr 3:106,947,827...106,996,199 		JBrowse link
G Mbip MAP3K12 binding inhibitory protein 1 involved_in ISO (PMID:10801814), (PMID:32963352) RGD PMID:10801814 PMID:32963352 NCBI chr 6:73,808,133...73,825,394
Ensembl chr 6:73,808,133...73,825,374 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO
IEA 		(PMID:28471450)
GO_REF:0000107 		RGD
Ensembl		 PMID:28471450 GO_REF:0000107 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Mink1 misshapen-like kinase 1 involved_in ISO
IEA 		(PMID:15469942)
GO_REF:0000107
(PMID:10708748) 		RGD
Ensembl		 PMID:10708748 PMID:15469942 GO_REF:0000107 NCBI chr10:55,776,879...55,829,406
Ensembl chr10:55,278,391...55,330,782 		JBrowse link
G Mir92a1 microRNA 92a-1 involved_in ISO (PMID:24332650) RGD PMID:24332650 NCBI chr15:98,588,555...98,588,632
Ensembl chr15:92,181,336...92,181,413 		JBrowse link
G Mir92a2 microRNA 92a-2 involved_in ISO (PMID:24332650) RGD PMID:24332650 NCBI chr  X:132,421,942...132,422,033
Ensembl chr  X:132,421,942...132,422,033 		JBrowse link
G Mturn maturin, neural progenitor differentiation regulator homolog involved_in ISO
IEA 		(PMID:24681962)
GO_REF:0000107 		RGD
Ensembl		 PMID:24681962 GO_REF:0000107 NCBI chr 4:83,807,528...83,828,494
Ensembl chr 4:83,807,579...83,824,950 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within ISO
IEA 		MGI:2385681 (PMID:12855817)
GO_REF:0000107 		RGD
Ensembl		 PMID:12855817 GO_REF:0000107 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Myoc myocilin involved_in IEA
ISO 		GO_REF:0000107
(PMID:19188438) 		Ensembl
RGD		 PMID:19188438 GO_REF:0000107 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127 		JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 involved_in ISO (PMID:11865055) RGD PMID:11865055 NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO
IEA 		(PMID:18261938)
GO_REF:0000107 		RGD
Ensembl		 PMID:18261938 GO_REF:0000107 NCBI chr 4:85,391,142...85,442,281
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO
IEA 		(PMID:17187069)
(PMID:18261938)
GO_REF:0000107 		RGD
Ensembl		 PMID:17187069 PMID:18261938 GO_REF:0000107 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Nox1 NADPH oxidase 1 acts_upstream_of_or_within ISO
IEA 		MGI:3616995 (PMID:19661248)
GO_REF:0000107 		RGD
Ensembl		 PMID:19661248 GO_REF:0000107 NCBI chr  X:101,572,338...101,625,571
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nr2c2 nuclear receptor subfamily 2, group C, member 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:12296995) 		Ensembl
RGD		 PMID:12296995 GO_REF:0000107 NCBI chr 4:124,610,216...124,666,813
Ensembl chr 4:124,608,960...124,661,902 		JBrowse link
G Nrk Nik related kinase involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:10801798) 		GO_Central
RGD		 PMID:10801798 GO_REF:0000033 NCBI chr  X:102,365,765...102,462,957
Ensembl chr  X:102,365,765...102,459,657 		JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 involved_in ISO
ISS
IEA 		(PMID:28471450)
GO_REF:0000024
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:28471450 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:103,956,678...104,006,763
Ensembl chr 9:103,956,678...104,006,783 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in ISO
IEA 		(PMID:9500449)
GO_REF:0000107 		RGD
Ensembl		 PMID:9500449 GO_REF:0000107 NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISS
ISO 		GO_REF:0000024
(PMID:8670418) 		UniProt
RGD		 PMID:8670418 GO_REF:0000024 NCBI chr15:44,536,275...44,656,754
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO
IEA 		(PMID:21487011)
GO_REF:0000107 		RGD
Ensembl		 PMID:21487011 GO_REF:0000107 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rassf2 Ras association domain family member 2 acts_upstream_of_or_within
involved_in 		ISO
IBA
IEA 		(PMID:19962960)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:19962960 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:139,697,187...139,733,402
Ensembl chr 3:119,245,821...119,280,431 		JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 acts_upstream_of_or_within ISO
IEA 		MGI:104798 (PMID:17015619)
GO_REF:0000107 		RGD
Ensembl		 PMID:17015619 GO_REF:0000107 NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO
IEA 		(PMID:17389591)
(PMID:20125124)
GO_REF:0000107 		RGD
Ensembl		 PMID:17389591 PMID:20125124 GO_REF:0000107 NCBI chr17:31,044,983...31,077,167
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO
IEA 		MGI:2446070|MGI:2660793 (PMID:11894097), (PMID:11894098), (PMID:18261938)
GO_REF:0000107 		RGD
Ensembl		 PMID:11894097 PMID:11894098 PMID:18261938 GO_REF:0000107 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Rnf13 ring finger protein 13 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:23378536)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:23378536 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:141,927,887...142,061,801
Ensembl chr 2:141,927,909...142,061,801 		JBrowse link
G Serpinf2 serpin family F member 2 involved_in ISO
IEA 		(PMID:20008146)
GO_REF:0000107 		RGD
Ensembl		 PMID:20008146 GO_REF:0000107 NCBI chr10:60,770,698...60,778,782
Ensembl chr10:60,272,400...60,281,243 		JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in ISS
IBA
ISO 		GO_REF:0000024
GO_REF:0000033
(PMID:23963642), (PMID:27084103) 		UniProt
GO_Central
RGD		 PMID:23963642 PMID:27084103 GO_REF:0000024 GO_REF:0000033 NCBI chr16:33,746,396...33,912,127
Ensembl chr16:28,735,440...28,901,644 		JBrowse link
G Sh3rf2 SH3 domain containing ring finger 2 involved_in ISO
ISS
IBA
IEA 		(PMID:24130170)
GO_REF:0000024
GO_REF:0000033
GO_REF:0000107 		RGD
UniProt
GO_Central
Ensembl		 PMID:24130170 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr18:34,296,753...34,397,880
Ensembl chr18:34,046,879...34,146,856 		JBrowse link
G Sh3rf3 SH3 domain containing ring finger 3 involved_in ISO
IBA
IEA 		(PMID:20696164)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:20696164 GO_REF:0000033 GO_REF:0000107 NCBI chr20:27,306,937...27,642,315
Ensembl chr20:26,765,015...27,099,257 		JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO
IEA 		(PMID:20231852)
GO_REF:0000107 		RGD
Ensembl		 PMID:20231852 GO_REF:0000107 NCBI chr13:86,802,708...86,837,890
Ensembl chr13:84,270,316...84,305,497 		JBrowse link
G Stk3 serine/threonine kinase 3 acts_upstream_of_or_within ISO MGI:104798|MGI:1929004 (PMID:20080598) RGD PMID:20080598 NCBI chr 7:67,938,341...68,208,472
Ensembl chr 7:66,052,345...66,323,233 		JBrowse link
G Taok1 TAO kinase 1 involved_in ISO
ISS
IBA
IEA 		(PMID:16407310)
GO_REF:0000024
GO_REF:0000033
GO_REF:0000107 		RGD
UniProt
GO_Central
Ensembl		 PMID:16407310 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:62,871,198...62,989,049
Ensembl chr10:62,381,404...62,465,766 		JBrowse link
G Taok2 TAO kinase 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:10660600)
(PMID:22683681) 		Ensembl
RGD		 PMID:10660600 PMID:22683681 GO_REF:0000107 NCBI chr 1:190,906,236...190,925,359
Ensembl chr 1:181,475,711...181,494,613 		JBrowse link
G Taok3 TAO kinase 3 involved_in ISO
IEA 		(PMID:10924369)
GO_REF:0000107 		RGD
Ensembl		 PMID:10924369 GO_REF:0000107 NCBI chr12:44,973,180...45,134,439
Ensembl chr12:39,314,027...39,461,244 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:11544529) RGD PMID:11544529 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr3 toll-like receptor 3 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:27830702)
(PMID:16260493)
GO_REF:0000107 		RGD
Ensembl		 PMID:16260493 PMID:27830702 GO_REF:0000107 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of_or_within ISO
IEA 		MGI:1346877 (PMID:16260493), (PMID:18261938)
GO_REF:0000107 		RGD
Ensembl		 PMID:16260493 PMID:18261938 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO
IEA 		(PMID:17128265)
GO_REF:0000107 		RGD
Ensembl		 PMID:17128265 GO_REF:0000107 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within
involved_in 		ISO
IEA 		MGI:1346877 (PMID:16260493), (PMID:20080598)
(PMID:17389591)
GO_REF:0000107 		RGD
Ensembl		 PMID:16260493 PMID:17389591 PMID:20080598 GO_REF:0000107 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A involved_in IEA
ISO 		GO_REF:0000107
(PMID:12296995) 		Ensembl
RGD		 PMID:12296995 GO_REF:0000107 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695 		JBrowse link
G Tnfrsf19 TNF receptor superfamily member 19 involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795 		JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within ISO
IEA 		MGI:109520 (PMID:22073305)
GO_REF:0000107 		RGD
Ensembl		 PMID:22073305 GO_REF:0000107 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tnik TRAF2 and NCK interacting kinase involved_in ISO
IEA 		(PMID:10521462), (PMID:15342639)
GO_REF:0000107 		RGD
Ensembl		 PMID:10521462 PMID:15342639 GO_REF:0000107 NCBI chr 2:111,184,352...111,587,993
Ensembl chr 2:111,184,387...111,580,750 		JBrowse link
G Tpd52l1 TPD52 like 1 involved_in ISO
IBA
IEA 		(PMID:14761963)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:14761963 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109 		JBrowse link
G Traf4 Tnf receptor associated factor 4 involved_in ISO
IEA 		(PMID:16157600)
GO_REF:0000002
GO_REF:0000107 		RGD
InterPro
Ensembl		 PMID:16157600 GO_REF:0000002 GO_REF:0000107 NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:11751921) RGD PMID:11751921 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in ISO
IEA 		(PMID:23021218)
GO_REF:0000107 		RGD
Ensembl		 PMID:23021218 GO_REF:0000107 NCBI chr12:47,599,161...47,638,143
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
G Unc5cl unc-5 family C-terminal like acts_upstream_of_or_within
involved_in 		ISO
IBA
IEA 		(PMID:22158417)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:22158417 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:12,528,109...12,543,382
Ensembl chr 9:12,528,246...12,542,233 		JBrowse link
G Wnt16 Wnt family member 16 involved_in ISO
IEA 		(PMID:17200136)
GO_REF:0000107 		RGD
Ensembl		 PMID:17200136 GO_REF:0000107 NCBI chr 4:51,786,728...51,797,137
Ensembl chr 4:50,820,968...50,831,380 		JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of 		IEA
ISO 		GO_REF:0000107
(PMID:20032469)
(PMID:20034610) 		Ensembl
RGD		 PMID:20032469 PMID:20034610 GO_REF:0000107 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Wnt7a Wnt family member 7A involved_in IMP
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:18567805 GO_REF:0000033, RGD:4107045 NCBI chr 4:125,420,276...125,466,149
Ensembl chr 4:123,863,108...123,908,981 		JBrowse link
G Wnt7b Wnt family member 7B IDA
IMP 		RGD PMID:18177422 PMID:18177422 RGD:2292645, RGD:2292645 NCBI chr 7:118,514,684...118,559,316
Ensembl chr 7:116,634,814...116,679,581 		JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in ISO
IEA 		(PMID:11865055)
GO_REF:0000107 		RGD
Ensembl		 PMID:11865055 GO_REF:0000107 NCBI chr  X:125,756,107...125,803,979
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
G Zfp622 zinc finger protein 622 involved_in ISO (PMID:21771788) RGD PMID:21771788 NCBI chr 2:78,205,655...78,224,888
Ensembl chr 2:76,335,609...76,493,898 		JBrowse link
regulation of JNK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase acts_upstream_of_or_within ISO
IEA 		MGI:1857139 (PMID:15030387)
GO_REF:0000107 		RGD
Ensembl		 PMID:15030387 GO_REF:0000107 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Cops5 COP9 signalosome subunit 5 involved_in ISO
IEA 		(PMID:16410250)
GO_REF:0000107 		RGD
Ensembl		 PMID:16410250 GO_REF:0000107 NCBI chr 5:9,192,233...9,210,498
Ensembl chr 5:9,192,100...9,210,731 		JBrowse link
G Dusp19 dual specificity phosphatase 19 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:85,945,289...86,081,289
Ensembl chr 3:65,538,420...65,553,534 		JBrowse link
G Ephb1 Eph receptor B1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:9430661) 		UniProt
Ensembl
RGD		 PMID:9430661 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:102,507,549...102,944,839
Ensembl chr 8:102,507,549...102,944,839 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA
ISS 		(PMID:16410250)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:16410250 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 involved_in IMP PMID:11152698 UniProt PMID:11152698 RGD:8554109 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor involved_in ISO
IBA
ISS 		(PMID:12556535)
GO_REF:0000033
GO_REF:0000024 		RGD
GO_Central
UniProt		 PMID:12556535 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 involved_in ISO (PMID:14966141) RGD PMID:14966141 NCBI chr 9:49,696,573...49,822,353
Ensembl chr 9:42,200,278...42,326,698 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
GO_REF:0000002
(PMID:11562351) 		UniProt
Ensembl
InterPro
RGD		 PMID:11562351 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:78,355,048...78,372,884 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 involved_in ISO
IEA 		(PMID:10490659)
GO_REF:0000107
GO_REF:0000002 		RGD
Ensembl
InterPro		 PMID:10490659 GO_REF:0000002 GO_REF:0000107 NCBI chr 7:122,406,350...122,416,602
Ensembl chr 7:120,526,732...120,536,982 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:10629060) 		Ensembl
RGD		 PMID:10629060 GO_REF:0000107 NCBI chr10:14,422,936...14,463,387
Ensembl chr10:13,918,400...13,958,273 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:17348686 RGD:2298766 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mdfi MyoD family inhibitor involved_in ISO (PMID:12192039) RGD PMID:12192039 NCBI chr 9:13,156,806...13,175,218
Ensembl chr 9:13,156,866...13,175,217 		JBrowse link
G Mdfic MyoD family inhibitor domain containing involved_in ISO
IEA
IBA 		(PMID:12192039)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:12192039 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:43,972,310...44,052,162
Ensembl chr 4:43,972,507...44,052,161 		JBrowse link
G Mdfic2 MyoD family inhibitor domain containing 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:130,845,260...130,948,054
Ensembl chr 4:130,846,890...130,947,093 		JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:17386267) 		Ensembl
RGD		 PMID:17386267 GO_REF:0000107 NCBI chr13:22,308,532...22,530,978
Ensembl chr13:22,308,548...22,530,977 		JBrowse link
G Rap2a RAP2A, member of RAS oncogene family involved_in ISO
IEA 		(PMID:14966141)
GO_REF:0000107 		RGD
Ensembl		 PMID:14966141 GO_REF:0000107 NCBI chr15:97,596,848...97,597,338
Ensembl chr15:97,596,020...97,624,138 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 IMP RGD PMID:10811109 RGD:11534984 NCBI chr 3:33,296,211...33,414,119
Ensembl chr 3:12,898,266...13,013,984 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 NOT|involved_in ISO (PMID:12773577) RGD PMID:12773577 NCBI chr14:2,634,294...2,810,269
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
G Tnxb tenascin XB acts_upstream_of_or_within ISO
IEA 		MGI:3053791 (PMID:15212943)
GO_REF:0000107 		RGD
Ensembl		 PMID:15212943 GO_REF:0000107
G Traf2 Tnf receptor-associated factor 2 acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:12958312)
GO_REF:0000002
GO_REF:0000107 		RGD
InterPro
Ensembl		 PMID:12958312 GO_REF:0000002 GO_REF:0000107 NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Ulk4 unc-51 like kinase 4 acts_upstream_of_or_within ISO
IEA 		(PMID:24284070)
GO_REF:0000107 		RGD
Ensembl		 PMID:24284070 GO_REF:0000107 NCBI chr 8:129,548,431...129,843,555
Ensembl chr 8:120,670,866...120,966,924 		JBrowse link
G Zfp110 zinc finger protein 110 involved_in ISO (PMID:15668238) RGD PMID:15668238 NCBI chr 1:73,445,303...73,461,112
Ensembl chr 1:73,445,336...73,461,086 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      signal transduction 7313
        intracellular signal transduction 3197
          intracellular signaling cassette 2057
            MAPK cascade 877
              JNK cascade 190
                JUN phosphorylation 4
                negative regulation of JNK cascade + 39
                positive regulation of JNK cascade 106
                regulation of JNK cascade + 158
Path 2
Term Annotations click to browse term
  biological_process 20543
    biological regulation 13835
      regulation of biological process 13398
        signaling 7874
          signal transduction 7313
            intracellular signal transduction 3197
              intracellular signaling cassette 2057
                MAPK cascade 877
                  JNK cascade 190
                    JUN phosphorylation 4
                    negative regulation of JNK cascade + 39
                    positive regulation of JNK cascade 106
                    regulation of JNK cascade + 158
paths to the root