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Term:cytoplasmic sequestering of NF-kappaB
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Accession:GO:0007253 term browser browse the term
Definition:The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.
Synonyms:exact_synonym: cytoplasmic NF-kappaB retention;   cytoplasmic NF-kappaB sequestration;   cytoplasmic NF-kappaB storage;   cytoplasmic retention of NF-kappaB;   cytoplasmic sequestration of NF-kappaB;   cytoplasmic storage of NF-kappaB;   maintenance of NF-kappaB location in cytoplasm

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cytoplasmic sequestering of NF-kappaB term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCDC22 coiled-coil domain containing 22 involved_in IEA Ensembl
GO_REF:0000107 NCBI chr  X:43,285,232...43,303,865
Ensembl chr  X:43,285,246...43,307,204
JBrowse link
G FAF1 Fas associated factor 1 involved_in IEA Ensembl
GO_REF:0000107 NCBI chr 6:161,173,915...161,603,731
Ensembl chr 6:161,166,996...161,603,725
JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in IEA
(PMID:21873635) Ensembl
PMID:9343439 PMID:9918814 PMID:10620707 PMID:16580131 PMID:21873635 GO_REF:0000107 RGD:2298880 RGD:2298882 RGD:2298908 RGD:2298917 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,508,016...64,558,057
JBrowse link
G NFKBIB NFKB inhibitor beta involved_in IBA
(PMID:21873635) GO_Central
PMID:9343439 PMID:16580131 PMID:21873635 RGD:2298908 RGD:2298917 NCBI chr 6:47,703,644...47,712,661
Ensembl chr 6:47,703,636...47,712,664
JBrowse link
G PSMD10 proteasome 26S subunit, non-ATPase 10 involved_in IEA Ensembl
GO_REF:0000107 NCBI chr  X:88,540,261...88,548,593
Ensembl chr  X:88,540,376...88,548,560
JBrowse link
G TMSB4X thymosin beta 4 X-linked involved_in ISO (PMID:21343177) CAFA PMID:21343177 NCBI chr  X:9,649,516...9,651,662
Ensembl chr  X:9,650,179...9,651,661
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17269
    localization 5293
      maintenance of location 340
        maintenance of protein location 98
          cytoplasmic sequestering of protein 24
            cytoplasmic sequestering of transcription factor 14
              cytoplasmic sequestering of NF-kappaB 6
Path 2
Term Annotations click to browse term
  biological_process 17269
    metabolic process 10885
      cellular metabolic process 9224
        cellular aromatic compound metabolic process 5398
          nucleobase-containing compound metabolic process 5192
            nucleic acid metabolic process 4751
              RNA metabolic process 4204
                RNA biosynthetic process 3303
                  nucleic acid-templated transcription 3287
                    transcription, DNA-templated 3285
                      regulation of transcription, DNA-templated 3183
                        regulation of DNA-binding transcription factor activity 468
                          negative regulation of DNA-binding transcription factor activity 197
                            negative regulation of NF-kappaB transcription factor activity 93
                              cytoplasmic sequestering of NF-kappaB 6
paths to the root