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ONTOLOGY REPORT - ANNOTATIONS


Term:cytoplasmic sequestering of NF-kappaB
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Accession:GO:0007253 term browser browse the term
Definition:The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.
Synonyms:exact_synonym: cytoplasmic NF-kappaB retention;   cytoplasmic NF-kappaB sequestration;   cytoplasmic NF-kappaB storage;   cytoplasmic retention of NF-kappaB;   cytoplasmic sequestration of NF-kappaB;   cytoplasmic storage of NF-kappaB;   maintenance of NF-kappaB location in cytoplasm



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cytoplasmic sequestering of NF-kappaB term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFKBIA NFKB inhibitor alpha ISO RGD PMID:9343439 PMID:9918814 PMID:10620707 PMID:16580131 RGD:2298880 RGD:2298882 RGD:2298908 RGD:2298917 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
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G NFKBIB NFKB inhibitor beta ISO RGD PMID:9343439 PMID:16580131 RGD:2298908 RGD:2298917 NCBI chr19:38,899,666...38,908,889
Ensembl chr19:38,899,700...38,908,893
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19770
    biological regulation 13405
      regulation of molecular function 307
        regulation of DNA-binding transcription factor activity 29
          negative regulation of DNA-binding transcription factor activity 11
            cytoplasmic sequestering of transcription factor 3
              cytoplasmic sequestering of NF-kappaB 2
Path 2
Term Annotations click to browse term
  biological_process 19770
    cellular process 18460
      cellular metabolic process 11168
        cellular aromatic compound metabolic process 6823
          nucleobase-containing compound metabolic process 6564
            nucleic acid metabolic process 5957
              RNA metabolic process 5352
                regulation of RNA metabolic process 3951
                  regulation of RNA biosynthetic process 3507
                    regulation of DNA-templated transcription 3489
                      regulation of DNA-binding transcription factor activity 29
                        negative regulation of DNA-binding transcription factor activity 11
                          cytoplasmic sequestering of transcription factor 3
                            cytoplasmic sequestering of NF-kappaB 2
paths to the root