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Term:cytoplasmic sequestering of NF-kappaB
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Accession:GO:0007253 term browser browse the term
Definition:The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.
Synonyms:exact_synonym: cytoplasmic NF-kappaB retention;   cytoplasmic NF-kappaB sequestration;   cytoplasmic NF-kappaB storage;   cytoplasmic retention of NF-kappaB;   cytoplasmic sequestration of NF-kappaB;   cytoplasmic storage of NF-kappaB;   maintenance of NF-kappaB location in cytoplasm

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cytoplasmic sequestering of NF-kappaB term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc22 coiled-coil domain containing 22 involved_in ISO (PMID:23563313) UniProt PMID:23563313 NCBI chrNW_004955543:719,185...731,788
Ensembl chrNW_004955543:718,996...733,753
JBrowse link
G Faf1 Fas associated factor 1 involved_in ISO (PMID:14600157) UniProt PMID:14600157 NCBI chrNW_004955464:8,037,344...8,477,798
Ensembl chrNW_004955464:8,036,955...8,479,249
JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:16938301) RGD
PMID:9343439 PMID:9918814 PMID:10620707 PMID:16580131 PMID:16938301 RGD:2298880 RGD:2298882 RGD:2298908 RGD:2298917 NCBI chrNW_004955409:25,691,673...25,695,151
Ensembl chrNW_004955409:25,691,534...25,697,520
JBrowse link
G Nfkbib NFKB inhibitor beta ISO RGD PMID:9343439 PMID:16580131 RGD:2298908 RGD:2298917 NCBI chrNW_004955468:617,078...626,151
Ensembl chrNW_004955468:617,078...626,151
JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISO (PMID:18040287) UniProt PMID:18040287 NCBI chrNW_004955490:7,825,202...7,832,347
Ensembl chrNW_004955490:7,825,251...7,833,772
JBrowse link
G Tmsb4x thymosin beta 4 X-linked involved_in ISO (PMID:21343177) CAFA PMID:21343177 NCBI chrNW_004955544:266,397...268,447
Ensembl chrNW_004955544:266,397...268,447
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12195
    localization 4113
      maintenance of location 297
        maintenance of protein location 87
          cytoplasmic sequestering of protein 24
            cytoplasmic sequestering of transcription factor 14
              cytoplasmic sequestering of NF-kappaB 6
Path 2
Term Annotations click to browse term
  biological_process 12195
    metabolic process 7780
      cellular metabolic process 6663
        cellular aromatic compound metabolic process 3968
          nucleobase-containing compound metabolic process 3789
            nucleic acid metabolic process 3468
              RNA metabolic process 3009
                RNA biosynthetic process 2408
                  nucleic acid-templated transcription 2395
                    transcription, DNA-templated 2390
                      regulation of transcription, DNA-templated 2320
                        regulation of DNA-binding transcription factor activity 414
                          negative regulation of DNA-binding transcription factor activity 167
                            negative regulation of NF-kappaB transcription factor activity 78
                              cytoplasmic sequestering of NF-kappaB 6
paths to the root