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Term:cytoplasmic sequestering of NF-kappaB
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Accession:GO:0007253 term browser browse the term
Definition:The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.
Synonyms:exact_synonym: cytoplasmic NF-kappaB retention;   cytoplasmic NF-kappaB sequestration;   cytoplasmic NF-kappaB storage;   cytoplasmic retention of NF-kappaB;   cytoplasmic sequestration of NF-kappaB;   cytoplasmic storage of NF-kappaB;   maintenance of NF-kappaB location in cytoplasm

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cytoplasmic sequestering of NF-kappaB term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCDC22 coiled-coil domain containing 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:41,535,439...41,550,547
Ensembl chr  X:49,387,980...49,402,742
JBrowse link
G FAF1 Fas associated factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:49,679,198...50,207,129
Ensembl chr 1:51,188,540...51,606,904
JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in ISO (PMID:16938301) RGD
PMID:9343439 PMID:9918814 PMID:10620707 PMID:16580131 PMID:16938301 RGD:2298880 RGD:2298882 RGD:2298908 RGD:2298917 NCBI chr14:16,155,331...16,158,588 JBrowse link
G NFKBIB NFKB inhibitor beta ISO RGD PMID:9343439 PMID:16580131 RGD:2298908 RGD:2298917 NCBI chr19:36,005,797...36,015,897 JBrowse link
G PSMD10 proteasome 26S subunit, non-ATPase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:97,182,090...97,189,523
Ensembl chr  X:107,552,186...107,559,616
JBrowse link
G TMSB4X thymosin beta 4 X-linked involved_in ISO (PMID:21343177) CAFA PMID:21343177 NCBI chr  X:5,587,242...5,589,417 JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 15327
    localization 4790
      maintenance of location 317
        maintenance of protein location 89
          cytoplasmic sequestering of protein 24
            cytoplasmic sequestering of transcription factor 14
              cytoplasmic sequestering of NF-kappaB 6
Path 2
Term Annotations click to browse term
  biological_process 15327
    metabolic process 10016
      cellular metabolic process 8332
        cellular aromatic compound metabolic process 4936
          nucleobase-containing compound metabolic process 4737
            nucleic acid metabolic process 4328
              RNA metabolic process 3806
                RNA biosynthetic process 3027
                  nucleic acid-templated transcription 3011
                    transcription, DNA-templated 3009
                      regulation of transcription, DNA-templated 2908
                        regulation of DNA-binding transcription factor activity 437
                          negative regulation of DNA-binding transcription factor activity 178
                            negative regulation of NF-kappaB transcription factor activity 88
                              cytoplasmic sequestering of NF-kappaB 6
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