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ONTOLOGY REPORT - ANNOTATIONS


Term:I-kappaB kinase/NF-kappaB signaling
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Accession:GO:0007249 term browser browse the term
Definition:The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.
Synonyms:exact_synonym: I-kappaB kinase/NF-kappaB signal transduction;   NF-kappaB cascade;   canonical NF-kappaB signaling cascade
 related_synonym: I-kappaB kinase/NF-kappaB cascade;   activation of the inhibitor of kappa kinase;   p50-dependent NF-kappaB signaling



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I-kappaB kinase/NF-kappaB signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of
involved_in
ISO
IEA
MGI:87860 (MGI:4399009|PMID:18025176)
GO_REF:0000107
RGD
Ensembl
PMID:18025176 GO_REF:0000107 MGI:4399009 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of ISO MGI:87859 (MGI:4399009|PMID:18025176) RGD PMID:18025176 MGI:4399009 NCBI chr13:68,673,702...68,839,742
Ensembl chr13:68,673,722...68,839,742
JBrowse link
G Ajuba ajuba LIM protein acts_upstream_of
involved_in
ISO
IEA
(MGI:3581322|PMID:15870274)
GO_REF:0000107
RGD
Ensembl
PMID:15870274 GO_REF:0000107 MGI:3581322 NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021
JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:26514923) RGD PMID:26514923 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Ash1l ASH1 like histone lysine methyltransferase acts_upstream_of ISO (MGI:5562489|PMID:24012418) RGD PMID:24012418 MGI:5562489 NCBI chr 2:174,346,267...174,483,057
Ensembl chr 2:174,346,150...174,483,055
JBrowse link
G Avpr2 arginine vasopressin receptor 2 acts_upstream_of_or_within ISO MGI:2384212 (MGI:1340165|PMID:10395695) RGD PMID:10395695 MGI:1340165 NCBI chr  X:151,633,501...151,636,000
Ensembl chr  X:151,633,522...151,635,989
JBrowse link
G Azi2 5-azacytidine induced 2 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
(MGI:1349559|PMID:10580148)
GO_REF:0000107
RGD
Ensembl
PMID:10580148 PMID:21873635 GO_REF:0000107 MGI:1349559, RGD:13792537 NCBI chr 8:117,773,248...117,797,844
Ensembl chr 8:117,773,279...117,797,847
JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2158304 (MGI:1930354|PMID:11163238)
RGD PMID:11163238 PMID:21873635 MGI:1930354, RGD:13792537 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523
JBrowse link
G Bcl3 BCL3, transcription coactivator involved_in ISO (PMID:8196632) RGD PMID:8196632 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Btk Bruton tyrosine kinase acts_upstream_of_or_within ISO MGI:1857138 (MGI:2680750|PMID:14597404) RGD PMID:14597404 MGI:2680750 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G Card11 caspase recruitment domain family, member 11 involved_in
acts_upstream_of
ISO (PMID:28628108)
MGI:3039682 (MGI:3039643|PMID:12867038)
RGD PMID:12867038 PMID:28628108 MGI:3039643 NCBI chr12:13,620,979...13,758,115
Ensembl chr12:13,621,087...13,758,112
JBrowse link
G Card9 caspase recruitment domain family, member 9 IMP RGD PMID:11053425 RGD:1299399 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Cd74 CD74 molecule involved_in ISO (PMID:23736979) RGD PMID:23736979 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex involved_in
acts_upstream_of
ISO (PMID:26514923)
MGI:1100089|MGI:3045616 (MGI:3045614|PMID:11747812)
RGD PMID:11747812 PMID:26514923 MGI:3045614 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of ISO (MGI:4355652|PMID:19619491) RGD PMID:19619491 MGI:4355652 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Defb25 defensin beta 25 involved_in ISO
IBA
(PMID:24955228)
PMID:21873635
RGD PMID:24955228 PMID:21873635 RGD:13792537 NCBI chr 3:141,098,856...141,099,696
Ensembl chr 3:141,098,856...141,099,696
JBrowse link
G Edn1 endothelin 1 involved_in ISO (MGI:6453700|PMID:24722437) RGD PMID:24722437 MGI:6453700 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A involved_in ISO MGI:102720 (MGI:6453700|PMID:24722437) RGD PMID:24722437 MGI:6453700 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Ednrb endothelin receptor type B involved_in ISO MGI:105923 (MGI:6453700|PMID:24722437) RGD PMID:24722437 MGI:6453700 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Faim Fas apoptotic inhibitory molecule involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:15520226 PMID:21873635 RGD:1357927, RGD:13792537 NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase acts_upstream_of ISO MGI:1927596 (MGI:5545939|PMID:23169819) RGD PMID:23169819 MGI:5545939 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B acts_upstream_of ISO MGI:95602 (MGI:5545939|PMID:23169819) RGD PMID:23169819 MGI:5545939 NCBI chr 1:173,316,398...173,340,951
Ensembl chr 1:173,316,907...173,340,932
JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 acts_upstream_of_or_within ISO (MGI:1859506|PMID:10747961) RGD PMID:10747961 MGI:1859506 NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta involved_in ISO (PMID:15383541), (PMID:25816133) RGD PMID:15383541 PMID:25816133 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il1b interleukin 1 beta acts_upstream_of ISO MGI:1346877 (MGI:3607973|PMID:16260493) RGD PMID:16260493 MGI:3607973 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Irak1bp1 interleukin-1 receptor-associated kinase 1 binding protein 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1931897|PMID:11096118)
RGD PMID:11096118 PMID:21873635 MGI:1931897, RGD:13792537 NCBI chr 8:83,731,512...83,748,289
Ensembl chr 8:83,731,507...83,748,289
JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602
JBrowse link
G Irf1 interferon regulatory factor 1 IMP RGD PMID:15141302 RGD:5128786 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G LOC684466 similar to Fas apoptotic inhibitory molecule 1 (rFAIM) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:99,791,849...99,810,206
Ensembl chr 8:99,791,981...99,810,228
JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 involved_in ISO
IBA
(MGI:1931349|PMID:11239468)
PMID:21873635
RGD PMID:11239468 PMID:21873635 MGI:1931349, RGD:13792537 NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of ISO MGI:104798|MGI:2156367|MGI:96536 (MGI:3607973|PMID:16260493) RGD PMID:16260493 MGI:3607973 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of
involved_in
ISO
IEA
MGI:2147032|MGI:2385681 (MGI:2669022|PMID:12855817)
GO_REF:0000107
RGD
Ensembl
PMID:12855817 GO_REF:0000107 MGI:2669022 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Myo18a myosin XVIIIa involved_in ISO (PMID:9918798) RGD PMID:9918798 NCBI chr10:62,654,218...62,755,464
Ensembl chr10:62,654,281...62,755,468
JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:25038658) RGD PMID:25038658 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbil1 NFKB inhibitor like 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5305914|PMID:22024480)
RGD PMID:22024480 PMID:21873635 MGI:5305914, RGD:13792537 NCBI chr20:3,589,974...3,608,348
Ensembl chr20:3,590,642...3,605,616
JBrowse link
G Nkiras2 NFKB inhibitor interacting Ras-like 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:85,554,704...85,562,072
Ensembl chr10:85,557,944...85,562,072
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in
acts_upstream_of
ISS
ISO
GO_REF:0000024
MGI:108072 (MGI:5437524|PMID:22863753)
(PMID:15705585)
UniProt
RGD
PMID:15705585 PMID:22863753 GO_REF:0000024 MGI:5437524 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:3775161|PMID:18261938)
GO_REF:0000107
RGD
Ensembl
PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of
involved_in
ISO
IEA
(MGI:3775161|PMID:18261938)
GO_REF:0000107
RGD
Ensembl
PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:11912207 PMID:21873635 RGD:2300288, RGD:13792537 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 involved_in
acts_upstream_of
ISO (MGI:5285496|PMID:21469090)
MGI:2446070|MGI:2660793 (MGI:2176422|PMID:11894098), (MGI:2176424|PMID:11894097), (MGI:3775161|PMID:18261938)
RGD PMID:11894097 PMID:11894098 PMID:18261938 PMID:21469090 MGI:2176422 MGI:2176424 MGI:3775161 MGI:5285496 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 acts_upstream_of_or_within ISO (MGI:1345788|PMID:10490590) RGD PMID:10490590 MGI:1345788 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO
IEA
(PMID:25816133)
GO_REF:0000107
RGD
Ensembl
PMID:25816133 GO_REF:0000107 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO
IEA
(PMID:25816133)
GO_REF:0000107
RGD
Ensembl
PMID:25816133 GO_REF:0000107 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
JBrowse link
G Snip1 Smad nuclear interacting protein 1 acts_upstream_of_or_within ISO (MGI:2154675|PMID:11567019) RGD PMID:11567019 MGI:2154675 NCBI chr 5:137,328,371...137,335,846
Ensembl chr 5:137,328,371...137,335,845
JBrowse link
G Tank TRAF family member-associated NFKB activator involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:82296|PMID:8710854)
RGD PMID:8710854 PMID:21873635 MGI:82296, RGD:13792537 NCBI chr 3:46,114,253...46,190,270
Ensembl chr 3:46,114,274...46,190,264
JBrowse link
G Tbkbp1 TBK1 binding protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:82,120,558...82,135,749
Ensembl chr10:82,120,564...82,134,352
JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 acts_upstream_of ISO MGI:108005|MGI:3029019 (MGI:2669022|PMID:12855817) RGD PMID:12855817 MGI:2669022 NCBI chr 9:1,102,559...1,115,573
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
G Tifa TRAF-interacting protein with forkhead-associated domain involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
(MGI:2159087|PMID:11798190)
GO_REF:0000002
RGD
InterPro
PMID:11798190 PMID:21873635 GO_REF:0000002 MGI:2159087, RGD:13792537 NCBI chr 2:216,257,926...216,267,635
Ensembl chr 2:216,234,774...216,267,841
JBrowse link
G Tifab TIFA inhibitor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592
JBrowse link
G Tirap TIR domain containing adaptor protein acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:2152194|PMID:11526399)
PMID:21873635
RGD PMID:11526399 PMID:21873635 MGI:2152194, RGD:13792537 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432
JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of ISO MGI:1346877|MGI:3690535 (MGI:2669022|PMID:12855817), (MGI:3607973|PMID:16260493) RGD PMID:12855817 PMID:16260493 MGI:2669022 MGI:3607973 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of ISO (MGI:3607973|PMID:16260493), (MGI:3775161|PMID:18261938) RGD PMID:16260493 PMID:18261938 MGI:3607973 MGI:3775161 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr8 toll-like receptor 8 involved_in ISO
IBA
(PMID:12032557)
PMID:21873635
RGD PMID:12032557 PMID:21873635 RGD:13792537 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549
JBrowse link
G Tlr9 toll-like receptor 9 involved_in IBA
ISO
PMID:21873635
(MGI:3826712|PMID:18820679)
RGD PMID:18820679 PMID:21873635 MGI:3826712, RGD:13792537 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of
involved_in
ISO
IEA
MGI:1346877 (MGI:3039643|PMID:12867038), (MGI:3607973|PMID:16260493)
GO_REF:0000107
RGD
Ensembl
PMID:12867038 PMID:16260493 GO_REF:0000107 MGI:3039643 MGI:3607973 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of
involved_in
ISO
IEA
(MGI:3848090|PMID:19298785)
GO_REF:0000107
RGD
Ensembl
PMID:19298785 GO_REF:0000107 MGI:3848090 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 acts_upstream_of_or_within ISO (MGI:2179873|PMID:11390377) RGD PMID:11390377 MGI:2179873 NCBI chr14:76,228,283...76,246,609
Ensembl chr14:76,228,371...76,275,265
JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in
acts_upstream_of
ISO (MGI:4442152|PMID:17633018)
MGI:2444070 (MGI:5437524|PMID:22863753)
RGD PMID:17633018 PMID:22863753 MGI:4442152 MGI:5437524 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
I-kappaB phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chuk component of inhibitor of nuclear factor kappa B kinase complex involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
ISO
GO_REF:0000024
(MGI:4453088|PMID:19948740)
UniProt
RGD
PMID:19948740 GO_REF:0000024 MGI:4453088 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 IDA RGD PMID:12133632 RGD:1626124 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762
JBrowse link
G Erc1 ELKS/RAB6-interacting/CAST family member 1 involved_in ISO
IEA
(PMID:15218148)
GO_REF:0000107
RGD
Ensembl
PMID:15218148 GO_REF:0000107 NCBI chr 4:152,763,664...153,055,706
Ensembl chr 4:152,767,419...153,055,639
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000108
(MGI:3836513|PMID:18981174)
GOC
RGD
PMID:18981174 GO_REF:0000108 MGI:3836513 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000108
(MGI:1928258|PMID:10421793)
GOC
RGD
PMID:10421793 GO_REF:0000108 MGI:1928258 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:11460167)
MGI:104798|MGI:96536 (MGI:3607973|PMID:16260493)
GO_REF:0000024
RGD
UniProt
PMID:11460167 PMID:16260493 GO_REF:0000024 MGI:3607973 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Tlr2 toll-like receptor 2 involved_in ISO (PMID:19740627) RGD PMID:19740627 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr3 toll-like receptor 3 involved_in ISO (PMID:19740627) RGD PMID:19740627 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:19740627)
MGI:1860885 (MGI:3835701|PMID:18820689)
GO_REF:0000107
RGD
Ensembl
PMID:18820689 PMID:19740627 GO_REF:0000107 MGI:3835701 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr7 toll-like receptor 7 involved_in ISO (PMID:19740627) RGD PMID:19740627 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754
JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (PMID:19740627) RGD PMID:19740627 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Usp25 ubiquitin specific peptidase 25 involved_in ISO MGI:4332130 (MGI:5441108|PMID:23042150) RGD PMID:23042150 MGI:5441108 NCBI chr11:15,603,654...15,711,356
Ensembl chr11:15,603,881...15,711,348
JBrowse link
negative regulation of I-kappaB kinase/NF-kappaB signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:108086 (MGI:4366111|PMID:19805123) RGD PMID:19805123 MGI:4366111 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO
ISS
(PMID:10982546)
GO_REF:0000024
RGD
UniProt
PMID:10982546 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Ash1l ASH1 like histone lysine methyltransferase acts_upstream_of_or_within ISO (MGI:5562489|PMID:24012418) RGD PMID:24012418 MGI:5562489 NCBI chr 2:174,346,267...174,483,057
Ensembl chr 2:174,346,150...174,483,055
JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:26363554) RGD PMID:26363554 NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829
JBrowse link
G Casp8 caspase 8 involved_in ISO (PMID:17047155) RGD PMID:17047155 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Ccdc22 coiled-coil domain containing 22 involved_in ISO (PMID:23563313) RGD PMID:23563313 NCBI chr  X:14,898,296...14,910,244
Ensembl chr  X:14,898,296...14,910,244
JBrowse link
G Coro1a coronin 1A involved_in ISO (PMID:25093672) RGD PMID:25093672 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO
ISS
(PMID:15310755), (PMID:17389591)
GO_REF:0000024
RGD
UniProt
PMID:15310755 PMID:17389591 GO_REF:0000024 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 involved_in ISO (PMID:11927590) RGD PMID:11927590 NCBI chr10:10,855,510...10,880,175
Ensembl chr10:10,854,732...10,880,161
JBrowse link
G Esr1 estrogen receptor 1 involved_in ISO
IEA
ISS
(PMID:16043358), (PMID:7651415)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:7651415 PMID:16043358 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5009411|PMID:16023107)
BHF-UCL
RGD
PMID:16023107 GO_REF:0000024 MGI:5009411 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hdac1 histone deacetylase 1 acts_upstream_of_or_within ISO MGI:87859 (MGI:4366111|PMID:19805123) RGD PMID:19805123 MGI:4366111 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 acts_upstream_of_or_within ISO (MGI:3723275|PMID:17623648) RGD PMID:17623648 MGI:3723275 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:19380766) RGD PMID:19380766 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
JBrowse link
G Mapkbp1 mitogen activated protein kinase binding protein 1 involved_in ISO
IBA
(PMID:22700971)
PMID:21873635
RGD PMID:22700971 PMID:21873635 RGD:13792537 NCBI chr 3:106,947,342...106,998,368
Ensembl chr 3:106,947,827...106,996,199
JBrowse link
G Mir15b microRNA 15b involved_in ISO (PMID:23487264) RGD PMID:23487264 NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297
JBrowse link
G Mir16 microRNA 16 involved_in ISO (PMID:23487264) RGD PMID:23487264 NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443
JBrowse link
G Mir195 microRNA 195 involved_in ISO (PMID:23487264) RGD PMID:23487264 NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924
JBrowse link
G Mir497 microRNA 497 involved_in ISO (PMID:23487264) RGD PMID:23487264 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584
JBrowse link
G Nfkbid NFKB inhibitor delta acts_upstream_of_or_within ISO (MGI:2177878|PMID:11931770) RGD PMID:11931770 MGI:2177878 NCBI chr 1:85,679,353...85,690,415
Ensembl chr 1:85,680,861...85,690,447
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:22863753)
MGI:108072 (MGI:5437524|PMID:22863753)
RGD PMID:22863753 PMID:21873635 MGI:5437524, RGD:13792537 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398
JBrowse link
G Nlrp12 NLR family, pyrin domain containing 12 involved_in IBA
ISO
PMID:21873635
(PMID:16203735)
RGD PMID:16203735 PMID:21873635 RGD:13792537 NCBI chr 1:65,932,610...65,969,873
Ensembl chr 1:65,932,595...65,960,934
JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B involved_in ISO (PMID:11551959) RGD PMID:11551959 NCBI chr10:55,838,381...55,904,374
Ensembl chr10:55,843,001...55,912,774
JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 acts_upstream_of_or_within ISO MGI:5085850 (MGI:5432950|PMID:22763455) RGD PMID:22763455 MGI:5432950 NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113
JBrowse link
G Nlrx1 NLR family member X1 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
MGI:5141085 (MGI:5050761|PMID:21703540)
GO_REF:0000107
RGD
Ensembl
PMID:21703540 PMID:21873635 GO_REF:0000107 MGI:5050761, RGD:13792537 NCBI chr 8:44,588,476...44,606,678
Ensembl chr 8:44,590,048...44,606,484
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6283959|PMID:30792350)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:30792350 GO_REF:0000024 GO_REF:0000107 MGI:6283959 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO
IEA
(PMID:21242261)
GO_REF:0000107
(MGI:5707586|PMID:18972444)
RGD
Ensembl
PMID:18972444 PMID:21242261 GO_REF:0000107 MGI:5707586 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Olfm4 olfactomedin 4 acts_upstream_of_or_within ISO (MGI:4457946|PMID:20534456) RGD PMID:20534456 MGI:4457946 NCBI chr15:55,385,100...55,429,687
Ensembl chr15:55,407,148...55,429,681
JBrowse link
G Optn optineurin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3766891|PMID:17702576)
Ensembl
RGD
PMID:17702576 GO_REF:0000107 MGI:3766891 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251
JBrowse link
G Otud7a OTU deubiquitinase 7A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:117,064,428...117,388,217
Ensembl chr 1:117,064,496...117,386,480
JBrowse link
G Otud7b OTU deubiquitinase 7B involved_in ISO (PMID:11463333)
(MGI:5474156|PMID:23334419)
RGD PMID:11463333 PMID:23334419 MGI:5474156 NCBI chr 2:183,661,955...183,722,584
Ensembl chr 2:183,662,163...183,718,674
JBrowse link
G Per1 period circadian regulator 1 involved_in IMP PMID:24447840 UniProt PMID:24447840 RGD:8655527 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A involved_in ISO
IEA
IBA
ISS
(PMID:18930133)
GO_REF:0000107
PMID:21873635
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:18930133 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697
JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:18930133)
UniProt
RGD
PMID:18930133 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974
JBrowse link
G Ppm1n protein phosphatase, Mg2+/Mn2+ dependent 1N involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:78,929,350...78,934,435
Ensembl chr 1:78,929,351...78,932,685
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:12486103) RGD PMID:12486103 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rhoa ras homolog family member A IMP RGD PMID:17615156 RGD:1642824 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rhoh ras homolog family member H involved_in ISO (PMID:11809807) RGD PMID:11809807 NCBI chr14:42,341,135...42,371,971
Ensembl chr14:42,337,751...42,386,369
JBrowse link
G Riok3 RIO kinase 3 involved_in ISO (PMID:19557502) RGD PMID:19557502 NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (PMID:17047155) RGD PMID:17047155 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Rora RAR-related orphan receptor A involved_in ISO (PMID:11252722) RGD PMID:11252722 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:17680780) RGD PMID:17680780 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Stat1 signal transducer and activator of transcription 1 involved_in ISO (PMID:10848577) RGD PMID:10848577 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Tank TRAF family member-associated NFKB activator involved_in ISO (PMID:25861989) RGD PMID:25861989 NCBI chr 3:46,114,253...46,190,270
Ensembl chr 3:46,114,274...46,190,264
JBrowse link
G Tle1 TLE family member 1, transcriptional corepressor involved_in ISO (PMID:17680780) RGD PMID:17680780 NCBI chr 5:85,851,827...85,934,806
Ensembl chr 5:85,851,827...85,934,774
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:11463333), (PMID:15258597), (PMID:21127049)
(MGI:3777503|PMID:18342009), (MGI:4946158|PMID:21088135)
RGD PMID:11463333 PMID:15258597 PMID:18342009 PMID:21088135 PMID:21127049 MGI:3777503 MGI:4946158 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 involved_in IBA
ISO
PMID:21873635
(MGI:5319605|PMID:18212736)
(PMID:16684768)
RGD PMID:16684768 PMID:18212736 PMID:21873635 MGI:5319605, RGD:13792537 NCBI chr10:39,037,048...39,084,328
Ensembl chr10:39,037,058...39,077,625
JBrowse link
G Tnip3 TNFAIP3 interacting protein 3 involved_in ISO (PMID:17088249) RGD PMID:17088249 NCBI chr 4:94,867,258...94,908,780
Ensembl chr 4:94,811,097...94,907,605
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6695683|PMID:29663649) RGD PMID:29663649 MGI:6695683 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Trim39 tripartite motif-containing 39 involved_in ISO
IEA
ISS
(PMID:26363554)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:26363554 GO_REF:0000024 GO_REF:0000107 NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117
JBrowse link
G Trim59 tripartite motif-containing 59 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:22588174)
(MGI:5426715|PMID:22588174)
RGD PMID:22588174 PMID:21873635 MGI:5426715, RGD:13792537 NCBI chr 2:153,269,210...153,281,185
Ensembl chr 2:153,268,584...153,281,031
JBrowse link
G Usp10 ubiquitin specific peptidase 10 involved_in ISO
ISS
(PMID:25861989)
GO_REF:0000024
RGD
UniProt
PMID:25861989 GO_REF:0000024 NCBI chr19:47,972,858...48,014,900
Ensembl chr19:47,972,611...48,014,897
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO
GO_REF:0000024
(MGI:5142149|PMID:21616078)
(PMID:25861989)
UniProt
RGD
PMID:21616078 PMID:25861989 GO_REF:0000024 MGI:5142149 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
JBrowse link
G Zmynd11 zinc finger, MYND-type containing 11 involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr17:60,542,669...60,631,913
Ensembl chr17:60,543,077...60,631,902
JBrowse link
negative regulation of I-kappaB phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir27b microRNA 27b acts_upstream_of_or_within ISO UniProtKB:P01375 (PMID:31124343) RGD PMID:31124343 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
JBrowse link
G Sirpa signal-regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568) RGD PMID:17954568 MGI:3760575 NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098
JBrowse link
positive regulation of I-kappaB kinase/NF-kappaB signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:87860 (MGI:4399009|PMID:18025176) RGD PMID:18025176 MGI:4399009 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:87859 (MGI:4399009|PMID:18025176) RGD PMID:18025176 MGI:4399009 NCBI chr13:68,673,702...68,839,742
Ensembl chr13:68,673,722...68,839,742
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:3055867|PMID:14522956), (MGI:3055868|PMID:12087086)
UniProt
RGD
PMID:12087086 PMID:14522956 GO_REF:0000024 MGI:3055867 MGI:3055868 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Ajuba ajuba LIM protein acts_upstream_of_or_within ISO (MGI:3581322|PMID:15870274) RGD PMID:15870274 MGI:3581322 NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021
JBrowse link
G Akap13 A-kinase anchoring protein 13 involved_in ISO
IMP
IBA
ISS
(PMID:23090968)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:23090968 PMID:23090968 PMID:21873635 GO_REF:0000024, RGD:11059571, RGD:13792537 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
JBrowse link
G Alpk1 alpha-kinase 1 involved_in ISO (PMID:28222186), (PMID:28877472), (PMID:30111836) RGD PMID:28222186 PMID:28877472 PMID:30111836 NCBI chr 2:216,126,939...216,247,180
Ensembl chr 2:216,128,825...216,247,157
JBrowse link
G Ankrd17 ankyrin repeat domain 17 involved_in ISO (PMID:22328336) RGD PMID:22328336 NCBI chr14:17,723,239...17,862,625
Ensembl chr14:17,721,932...17,862,617
JBrowse link
G Apol3 apolipoprotein L3 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 7:109,288,725...109,297,728
Ensembl chr 7:109,288,725...109,297,723
JBrowse link
G Atp2c1 ATPase secretory pathway Ca2+ transporting 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 8:106,034,777...106,155,854
Ensembl chr 8:106,034,636...106,156,006
JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in ISS
ISO
GO_REF:0000024
(PMID:12761501), (PMID:18287044), (PMID:27777308)
UniProt
RGD
PMID:12761501 PMID:18287044 PMID:27777308 GO_REF:0000024 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Brd4 bromodomain containing 4 involved_in ISO (PMID:19103749) RGD PMID:19103749 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr16:18,217,404...18,220,979
Ensembl chr16:18,217,407...18,220,979
JBrowse link
G Cant1 calcium activated nucleotidase 1 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr10:103,637,079...103,650,240
Ensembl chr10:103,531,504...103,650,109
JBrowse link
G Card11 caspase recruitment domain family, member 11 involved_in
acts_upstream_of_or_within
ISO (PMID:12154360)
(MGI:6695669|PMID:12154356)
MGI:3039682 (MGI:3039643|PMID:12867038)
RGD PMID:12154356 PMID:12154360 PMID:12867038 MGI:3039643 MGI:6695669 NCBI chr12:13,620,979...13,758,115
Ensembl chr12:13,621,087...13,758,112
JBrowse link
G Card9 caspase recruitment domain family, member 9 involved_in ISO
IBA
(PMID:11053425)
PMID:21873635
RGD PMID:11053425 PMID:21873635 RGD:13792537 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Casp1 caspase 1 involved_in ISO
IEA
(PMID:12761501), (PMID:15383541)
(MGI:3773087|PMID:16585594)
GO_REF:0000107
RGD
Ensembl
PMID:12761501 PMID:15383541 PMID:16585594 GO_REF:0000107 MGI:3773087 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp8 caspase 8 involved_in ISO (PMID:12761501), (PMID:12884866) RGD PMID:12761501 PMID:12884866 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cc2d1a coiled-coil and C2 domain containing 1A involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr19:24,011,897...24,026,937
Ensembl chr19:24,011,938...24,026,936
JBrowse link
G Ccdc22 coiled-coil domain containing 22 involved_in ISO (PMID:23563313) RGD PMID:23563313 NCBI chr  X:14,898,296...14,910,244
Ensembl chr  X:14,898,296...14,910,244
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:15059845) RGD PMID:15059845 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
JBrowse link
G Ccl21 C-C motif chemokine ligand 21 involved_in ISO (PMID:15059845) RGD PMID:15059845 NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686
JBrowse link
G Cd36 CD36 molecule acts_upstream_of_or_within ISO MGI:2447190 (MGI:3587138|PMID:16061696) RGD PMID:16061696 MGI:3587138 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd4 Cd4 molecule involved_in ISO (PMID:24942581) RGD PMID:24942581 NCBI chr 4:157,668,878...157,695,366 JBrowse link
G Cd40 CD40 molecule involved_in ISO
IBA
(PMID:12761501)
PMID:21873635
RGD PMID:12761501 PMID:21873635 RGD:13792537 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd74 CD74 molecule involved_in ISO (PMID:24942581) RGD PMID:24942581 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex involved_in
acts_upstream_of_or_within
ISO (PMID:23487264)
MGI:1100089|MGI:3045616 (MGI:3045614|PMID:11747812)
RGD PMID:11747812 PMID:23487264 MGI:3045614 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Clec4a C-type lectin domain family 4, member A involved_in ISO (MGI:4887333|PMID:17050534) RGD PMID:17050534 MGI:4887333 NCBI chr 4:156,340,439...156,434,212
Ensembl chr 4:156,414,688...156,432,402
JBrowse link
G Clec4d C-type lectin domain family 4, member D involved_in IEA
ISO
GO_REF:0000107
(MGI:5562511|PMID:23911656)
Ensembl
RGD
PMID:23911656 GO_REF:0000107 MGI:5562511 NCBI chr 4:156,589,591...156,598,969
Ensembl chr 4:156,589,792...156,598,848
JBrowse link
G Clec4n C-type lectin domain family 4, member n involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr 4:156,539,408...156,558,605 JBrowse link
G Clec6a-ps1 C-type lectin domain family 6, member A, pseudogene 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:156,539,408...156,559,032 JBrowse link
G Cth cystathionine gamma-lyase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5304595|PMID:22244329)
UniProt
Ensembl
RGD
PMID:22244329 GO_REF:0000024 GO_REF:0000107 MGI:5304595 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO (MGI:4355652|PMID:19619491) RGD PMID:19619491 MGI:4355652 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in IGI PMID:12729461 ARUK-UCL PMID:12729461 RGD:13673777 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cxxc5 CXXC finger protein 5 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr18:27,427,591...27,458,579
Ensembl chr18:27,427,230...27,458,673
JBrowse link
G Ddx1 DEAD-box helicase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5050760|PMID:21703541)
UniProt
RGD
PMID:21703541 GO_REF:0000024 MGI:5050760 NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365
JBrowse link
G Ddx21 DExD-box helicase 21 involved_in ISS
ISO
GO_REF:0000024
(MGI:5050760|PMID:21703541)
UniProt
RGD
PMID:21703541 GO_REF:0000024 MGI:5050760 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543
JBrowse link
G Dhx15 DEAH-box helicase 15 involved_in ISO (PMID:24990078) RGD PMID:24990078 NCBI chr14:58,787,147...58,825,083
Ensembl chr14:58,787,127...58,825,088
JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISS
ISO
GO_REF:0000024
(MGI:5050760|PMID:21703541)
UniProt
RGD
PMID:21703541 GO_REF:0000024 MGI:5050760 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
JBrowse link
G Ecm1 extracellular matrix protein 1 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671
JBrowse link
G Ect2 epithelial cell transforming 2 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911
JBrowse link
G Eda ectodysplasin-A acts_upstream_of_or_within ISO MGI:1856197 (MGI:3813383|PMID:18689798) RGD PMID:18689798 MGI:3813383 NCBI chr  X:65,078,454...65,480,172
Ensembl chr  X:65,078,673...65,480,172
JBrowse link
G Eda2r ectodysplasin A2 receptor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:62,224,763...62,269,344
Ensembl chr  X:62,228,229...62,269,268
JBrowse link
G Edar ectodysplasin-A receptor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:26,587,836...26,666,543
Ensembl chr20:26,587,839...26,666,494
JBrowse link
G Eef1d eukaryotic translation elongation factor 1 delta involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799
JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in ISO
IEA
ISS
(PMID:12761501)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12761501 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
ISS
(PMID:11413129)
GO_REF:0000024
RGD
UniProt
PMID:11413129 GO_REF:0000024 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G Fadd Fas associated via death domain involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Faslg Fas ligand involved_in IBA
ISO
PMID:21873635
(PMID:12761501)
RGD PMID:12761501 PMID:21873635 RGD:13792537 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Flna filamin A involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO MGI:1927596 (MGI:5545939|PMID:23169819) RGD PMID:23169819 MGI:5545939 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase involved_in ISS
ISO
GO_REF:0000024
(PMID:23332158)
UniProt
RGD
PMID:23332158 GO_REF:0000024 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gja1 gap junction protein, alpha 1 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Golt1b golgi transport 1B involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 4:175,333,056...175,346,156
Ensembl chr 4:175,333,092...175,346,153
JBrowse link
G Gpr89b G protein-coupled receptor 89B involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 2:184,408,136...184,445,560
Ensembl chr 2:184,401,438...184,445,584
JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B acts_upstream_of_or_within
involved_in
ISO MGI:95602 (MGI:5545939|PMID:23169819) RGD PMID:23169819 MGI:5545939 NCBI chr 1:173,316,398...173,340,951
Ensembl chr 1:173,316,907...173,340,932
JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in ISO
IEA
ISS
(PMID:12761501)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12761501 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:86,735,793...86,756,640
Ensembl chr 9:86,742,102...86,755,108
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta involved_in ISO
IEA
(PMID:30337470)
GO_REF:0000107
RGD
Ensembl
PMID:30337470 GO_REF:0000107 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in
acts_upstream_of_or_within
IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:17702576)
(PMID:18287044)
UniProt
RGD
PMID:17702576 PMID:18287044 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:15671867 RGD:1358666 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta acts_upstream_of_or_within IDA
ISO
MGI:1346877 (MGI:3607973|PMID:16260493) RGD PMID:16260493 PMID:15671867 MGI:3607973, RGD:1358666 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 acts_upstream_of_or_within ISO (PMID:22158417) RGD PMID:22158417 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521
JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:22158417)
RGD PMID:22158417 PMID:21873635 RGD:13792537 NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837
JBrowse link
G Irf3 interferon regulatory factor 3 IMP RGD PMID:20670634 RGD:5128809 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Jmjd8 jumonji domain containing 8 involved_in ISS
ISO
GO_REF:0000024
(PMID:27671354)
UniProt
RGD
PMID:27671354 GO_REF:0000024 NCBI chr10:14,848,965...14,851,881
Ensembl chr10:14,848,980...14,851,879
JBrowse link
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 involved_in ISO (PMID:21343296) RGD PMID:21343296 NCBI chr 2:194,900,038...194,905,394
Ensembl chr 2:194,900,038...194,905,395
JBrowse link
G Lgals1 galectin 1 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895
JBrowse link
G Ltbr lymphotoxin beta receptor involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539
JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:20345905) RGD PMID:20345905 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
JBrowse link
G Lurap1 leucine rich adaptor protein 1 involved_in ISO
IBA
(PMID:21048106)
PMID:21873635
RGD PMID:21048106 PMID:21873635 RGD:13792537 NCBI chr 5:129,618,926...129,628,651
Ensembl chr 5:129,614,137...129,628,766
JBrowse link
G Lurap1l leucine rich adaptor protein 1-like involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:95,362,005...95,409,439
Ensembl chr 5:95,362,005...95,409,438
JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260
JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 involved_in ISO (PMID:10094049) RGD PMID:10094049 NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of_or_within
involved_in
IMP
ISO
IBA
MGI:104798|MGI:2156367|MGI:96536 (MGI:3607973|PMID:16260493)
PMID:21873635
(PMID:14982987)
RGD PMID:14982987 PMID:16260493 PMID:17947700 PMID:21873635 MGI:3607973, RGD:5508194, RGD:13792537 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
JBrowse link
G Mib2 MIB E3 ubiquitin protein ligase 2 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 5:166,243,776...166,259,944
Ensembl chr 5:166,243,776...166,259,650
JBrowse link
G Mid2 midline 2 involved_in ISO (PMID:23077300) RGD PMID:23077300 NCBI chr  X:104,354,692...104,456,757
Ensembl chr  X:104,355,316...104,453,473
JBrowse link
G Mier1 MIER1 transcriptional regulator involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 5:117,876,012...117,927,592
Ensembl chr 5:117,870,382...117,927,589
JBrowse link
G Mtdh metadherin involved_in ISO (PMID:16452207), (PMID:18316612) RGD PMID:16452207 PMID:18316612 NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413
JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within
involved_in
TAS
ISO
MGI:2147032|MGI:2385681 (MGI:2669022|PMID:12855817)
(PMID:12761501)
RGD PMID:12761501 PMID:12855817 PMID:14962484 MGI:2669022, RGD:1302746 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311
JBrowse link
G Ndfip2 Nedd4 family interacting protein 2 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr15:82,032,366...82,087,043
Ensembl chr15:82,032,366...82,086,317
JBrowse link
G Nek6 NIMA-related kinase 6 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 3:22,284,269...22,356,302
Ensembl chr 3:22,284,279...22,395,990
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (MGI:3775161|PMID:18261938)
(PMID:10329646)
RGD PMID:10329646 PMID:18261938 MGI:3775161 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:12527755)
(PMID:11087742)
(MGI:3775161|PMID:18261938)
RGD PMID:11087742 PMID:12527755 PMID:18261938 PMID:21873635 MGI:3775161, RGD:13792537 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Nup62 nucleoporin 62 involved_in ISO
ISS
(PMID:10356400)
GO_REF:0000024
RGD
UniProt
PMID:10356400 GO_REF:0000024 NCBI chr 1:95,298,995...95,314,902
Ensembl chr 1:95,295,526...95,315,174
JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO MGI:4361448 (MGI:4359971|PMID:19734906) RGD PMID:19734906 MGI:4359971 NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285
JBrowse link
G Pim2 Pim-2 proto-oncogene, serine/threonine kinase involved_in ISO (MGI:3510500|PMID:15548703) RGD PMID:15548703 MGI:3510500 NCBI chr  X:14,617,582...14,622,851
Ensembl chr  X:14,617,582...14,622,851
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:19880420) RGD PMID:19880420 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Plekhg5 pleckstrin homology and RhoGEF domain containing G5 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 5:162,577,999...162,621,518
Ensembl chr 5:162,578,071...162,621,513
JBrowse link
G Plin3 perilipin 3 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 9:1,111,178...1,123,117
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
G Plk2 polo-like kinase 2 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697
JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 1:77,690,203...77,714,507
Ensembl chr 1:77,690,208...77,714,456
JBrowse link
G Prkcb protein kinase C, beta involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:3626015|PMID:12118249)
UniProt
Ensembl
RGD
PMID:12118249 GO_REF:0000024 GO_REF:0000107 MGI:3626015 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prkce protein kinase C, epsilon acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:3609215 (MGI:3609210|PMID:11696589)
GO_REF:0000107
RGD
Ensembl
PMID:11696589 GO_REF:0000107 MGI:3609210 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prkd1 protein kinase D1 involved_in ISO
ISS
(PMID:12505989)
GO_REF:0000024
RGD
UniProt
PMID:12505989 GO_REF:0000024 NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS
ISO
GO_REF:0000024
(PMID:17314283), (PMID:19880420), (PMID:23453807)
ParkinsonsUK-UCL
RGD
PMID:17314283 PMID:19880420 PMID:23453807 GO_REF:0000024 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in IEA
ISO
IBA
ISS
GO_REF:0000107
(MGI:4437982|PMID:19136968)
PMID:21873635
GO_REF:0000024
(PMID:19136968), (PMID:21455173)
Ensembl
RGD
UniProt
PMID:19136968 PMID:21455173 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:4437982, RGD:13792537 NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:12761501)
(MGI:5304595|PMID:22244329)
RGD PMID:12761501 PMID:22244329 MGI:5304595 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G RGD1562987 similar to cDNA sequence BC031181 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr18:68,586,278...68,594,851
Ensembl chr18:68,586,211...68,596,787
JBrowse link
G RGD1565355 similar to fatty acid translocase/CD36 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:17,424,749...17,465,808
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Rhoa ras homolog family member A involved_in ISS
ISO
GO_REF:0000024
(PMID:12761501)
UniProt
RGD
PMID:12761501 GO_REF:0000024 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rhoc ras homolog family member C involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:12761501), (PMID:17389591)
(MGI:5521568|PMID:22089168)
RGD PMID:12761501 PMID:17389591 PMID:22089168 MGI:5521568 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:2446070|MGI:2660793 (MGI:2176422|PMID:11894098), (MGI:2176424|PMID:11894097), (MGI:3775161|PMID:18261938)
PMID:21873635
(PMID:10329646)
RGD PMID:10329646 PMID:11894097 PMID:11894098 PMID:18261938 PMID:21873635 MGI:2176422 MGI:2176424 MGI:3775161, RGD:13792537 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
JBrowse link
G Rnf31 ring finger protein 31 involved_in ISO (MGI:4462284|PMID:20614026)
(PMID:19136968), (PMID:21455173), (PMID:28481331)
RGD PMID:19136968 PMID:20614026 PMID:21455173 PMID:28481331 MGI:4462284 NCBI chr15:29,083,047...29,095,328
Ensembl chr15:29,083,631...29,101,915
JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 involved_in ISO
IBA
(PMID:27162350)
PMID:21873635
RGD PMID:27162350 PMID:21873635 RGD:13792537 NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:24942581) RGD PMID:24942581 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G S100a13 S100 calcium binding protein A13 involved_in ISO (PMID:15033494) RGD PMID:15033494 NCBI chr 2:175,999,439...176,005,933 JBrowse link
G S100a4 S100 calcium-binding protein A4 involved_in IBA
ISO
PMID:21873635
(PMID:15033494)
RGD PMID:15033494 PMID:21873635 RGD:13792537 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
JBrowse link
G S100b S100 calcium binding protein B involved_in IBA
ISO
PMID:21873635
(PMID:15033494)
RGD PMID:15033494 PMID:21873635 RGD:13792537 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
JBrowse link
G Sectm1b secreted and transmembrane 1B involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr10:106,325,202...106,333,769
Ensembl chr10:106,325,203...106,333,769
JBrowse link
G Sharpin SHANK-associated RH domain interactor involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:4947438|PMID:21455180), (MGI:4947439|PMID:21455173)
PMID:21873635
(PMID:21455173)
UniProt
RGD
PMID:21455173 PMID:21455180 PMID:21873635 GO_REF:0000024 MGI:4947438 MGI:4947439, RGD:13792537 NCBI chr 7:108,070,681...108,075,012
Ensembl chr 7:108,070,687...108,074,955
JBrowse link
G Shisa5 shisa family member 5 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 8:109,691,476...109,706,409
Ensembl chr 8:109,691,522...109,706,408
JBrowse link
G Slc20a1 solute carrier family 20 member 1 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051
JBrowse link
G Slc35b2 solute carrier family 35 member B2 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 9:15,438,594...15,442,227
Ensembl chr 9:15,438,594...15,442,234
JBrowse link
G Slc44a2 solute carrier family 44 member 2 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 8:19,870,867...19,905,345
Ensembl chr 8:19,870,888...19,905,342
JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 involved_in IBA
ISO
ISS
PMID:21873635
(PMID:12761501), (PMID:15327770), (PMID:22158122)
GO_REF:0000024
RGD
UniProt
PMID:12761501 PMID:15327770 PMID:22158122 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:2,375,026...2,424,759
Ensembl chr 1:2,375,490...2,424,756
JBrowse link
G Tab3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 involved_in IBA
ISO
PMID:21873635
(PMID:15327770), (PMID:22158122), (PMID:23487264)
RGD PMID:15327770 PMID:22158122 PMID:23487264 PMID:21873635 RGD:13792537 NCBI chr  X:49,972,414...50,044,658
Ensembl chr  X:49,972,330...50,042,056
JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
JBrowse link
G Terf2ip TERF2 interacting protein involved_in ISS
ISO
GO_REF:0000024
(MGI:4821187|PMID:20622870)
UniProt
RGD
PMID:20622870 GO_REF:0000024 MGI:4821187 NCBI chr19:39,976,965...39,984,055
Ensembl chr19:39,976,906...39,984,064
JBrowse link
G Tfg trafficking from ER to golgi regulator involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr11:43,885,542...43,911,976
Ensembl chr11:43,885,661...43,911,976
JBrowse link
G Tfrc transferrin receptor involved_in ISO (PMID:23016877) RGD PMID:23016877 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgm2 transglutaminase 2 IMP RGD PMID:15471861 RGD:1579987 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 involved_in
acts_upstream_of_or_within
ISO (PMID:14982987)
(MGI:5050760|PMID:21703541)
MGI:108005|MGI:3029019 (MGI:2669022|PMID:12855817)
RGD PMID:12855817 PMID:14982987 PMID:21703541 MGI:2669022 MGI:5050760 NCBI chr 9:1,102,559...1,115,573
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
G Ticam2 toll-like receptor adaptor molecule 2 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462
JBrowse link
G Tifa TRAF-interacting protein with forkhead-associated domain involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:26068852), (PMID:28222186), (PMID:28877472), (PMID:30111836)
PMID:21873635
UniProt
RGD
PMID:26068852 PMID:28222186 PMID:28877472 PMID:30111836 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:216,257,926...216,267,635
Ensembl chr 2:216,234,774...216,267,841
JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO
IBA
(PMID:19509286)
PMID:21873635
RGD PMID:19509286 PMID:21873635 RGD:13792537 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432
JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of_or_within ISO MGI:1346877|MGI:3690535 (MGI:2669022|PMID:12855817), (MGI:3607973|PMID:16260493), (MGI:4359971|PMID:19734906) RGD PMID:12855817 PMID:16260493 PMID:19734906 MGI:2669022 MGI:3607973 MGI:4359971 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3607973|PMID:16260493), (MGI:3775161|PMID:18261938), (MGI:4359971|PMID:19734906)
Ensembl
RGD
PMID:16260493 PMID:18261938 PMID:19734906 GO_REF:0000107 MGI:3607973 MGI:3775161 MGI:4359971 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr6 toll-like receptor 6 acts_upstream_of_or_within ISO (PMID:10231569) RGD PMID:10231569 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685
JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (PMID:17128265) RGD PMID:17128265 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Tmed4 transmembrane p24 trafficking protein 4 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr14:81,125,049...81,129,665
Ensembl chr14:81,125,053...81,129,631
JBrowse link
G Tmem101 transmembrane protein 101 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr10:87,105,115...87,108,868
Ensembl chr10:87,105,117...87,108,832
JBrowse link
G Tmem106a transmembrane protein 106A involved_in ISS
ISO
GO_REF:0000024
(MGI:6216178|PMID:26215746)
UniProt
RGD
PMID:26215746 GO_REF:0000024 MGI:6216178 NCBI chr10:86,506,908...86,515,915
Ensembl chr10:86,506,936...86,515,892
JBrowse link
G Tmem9b TMEM9 domain family, member B involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 1:163,755,307...163,783,880
Ensembl chr 1:163,764,433...163,783,278
JBrowse link
G Tnf tumor necrosis factor involved_in
acts_upstream_of_or_within
IGI
IDA
ISO
IBA
PMID:12729461
MGI:1346877 (MGI:3039643|PMID:12867038), (MGI:3607973|PMID:16260493), (MGI:5521568|PMID:22089168)
PMID:21873635
(PMID:15310755), (PMID:17922812)
RGD PMID:12867038 PMID:15310755 PMID:16260493 PMID:17922812 PMID:22089168 More... MGI:3039643 MGI:3607973 MGI:5521568, RGD:1580306, RGD:13673777, RGD:13792537 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf19 TNF receptor superfamily member 19 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1860663|PMID:10764796)
RGD PMID:10764796 PMID:21873635 MGI:1860663, RGD:13792537 NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnfsf10 TNF superfamily member 10 involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3848090|PMID:19298785)
GO_REF:0000107
RGD
Ensembl
PMID:19298785 GO_REF:0000107 MGI:3848090 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO
IBA
(PMID:21784860)
PMID:21873635
RGD PMID:21784860 PMID:21873635 RGD:13792537 NCBI chr14:76,228,283...76,246,609
Ensembl chr14:76,228,371...76,275,265
JBrowse link
G Tradd TNFRSF1A-associated via death domain involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638
JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in IBA
ISO
PMID:21873635
(MGI:5616328|PMID:11374864)
RGD PMID:11374864 PMID:21873635 MGI:5616328, RGD:13792537 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
G Traf3ip2 Traf3 interacting protein 2 involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667
JBrowse link
G Traf5 TNF receptor-associated factor 5 involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr13:103,569,944...103,618,756
Ensembl chr13:103,572,314...103,618,709
JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2444070 (MGI:5437524|PMID:22863753)
(MGI:3054342|PMID:15322147), (MGI:5499721|PMID:20345905)
(PMID:17135271)
UniProt
RGD
PMID:15322147 PMID:17135271 PMID:20345905 PMID:22863753 GO_REF:0000024 MGI:3054342 MGI:5437524 MGI:5499721 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Trim13 tripartite motif-containing 13 involved_in ISO
IBA
(PMID:23077300)
PMID:21873635
RGD PMID:23077300 PMID:21873635 RGD:13792537 NCBI chr15:35,733,548...35,772,676
Ensembl chr15:35,734,107...35,772,677
JBrowse link
G Trim14 tripartite motif-containing 14 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:60,800,032...60,825,481
Ensembl chr 5:60,800,032...60,824,858
JBrowse link
G Trim21 tripartite motif-containing 21 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:156,964,896...156,987,504
Ensembl chr 1:156,964,913...156,987,440
JBrowse link
G Trim25 tripartite motif-containing 25 involved_in ISO (PMID:23077300) RGD PMID:23077300 NCBI chr10:73,812,818...73,831,271
Ensembl chr10:73,812,818...73,831,257
JBrowse link
G Trim27 tripartite motif-containing 27 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:43,538,282...43,550,633
Ensembl chr17:43,538,285...43,550,643
JBrowse link
G Trim30 tripartite motif-containing 30 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:158,795,288...158,813,913
Ensembl chr 1:158,720,410...158,814,012
JBrowse link
G Trim30c tripartite motif-containing 30C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:158,766,401...158,787,915
Ensembl chr 1:158,765,969...158,787,183
JBrowse link
G Trim32 tripartite motif-containing 32 involved_in ISO (PMID:23077300) RGD PMID:23077300 NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018
JBrowse link
G Trim34 tripartite motif-containing 34 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:158,707,172...158,720,214
Ensembl chr 1:158,707,172...158,718,674
JBrowse link
G Trim38 tripartite motif containing 38 involved_in ISO (PMID:23077300) RGD PMID:23077300 NCBI chr17:41,351,857...41,365,021 JBrowse link
G Trim5 tripartite motif-containing 5 involved_in IBA
ISO
PMID:21873635
(PMID:21512573), (PMID:23077300)
RGD PMID:21512573 PMID:23077300 PMID:21873635 RGD:13792537 NCBI chr 1:158,720,407...158,737,393
Ensembl chr 1:158,720,410...158,814,012
JBrowse link
G Trim52 tripartite motif-containing 52 involved_in ISO (PMID:27667714), (PMID:28073078) RGD PMID:27667714 PMID:28073078 NCBI chr15:82,886,237...82,924,611
Ensembl chr15:82,886,237...82,909,759
JBrowse link
G Trim6 tripartite motif containing 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914
JBrowse link
G Trim62 tripartite motif-containing 62 involved_in IBA
ISO
PMID:21873635
(PMID:23077300)
RGD PMID:23077300 PMID:21873635 RGD:13792537 NCBI chr 5:141,230,830...141,260,629
Ensembl chr 5:141,231,523...141,259,915
JBrowse link
G Trim68 tripartite motif containing 68 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:157,114,044...157,127,494
Ensembl chr 1:157,114,044...157,127,477
JBrowse link
G Trim8 tripartite motif-containing 8 involved_in ISO (PMID:23077300) RGD PMID:23077300 NCBI chr 1:245,369,632...245,384,513
Ensembl chr 1:245,369,632...245,384,513
JBrowse link
G Triml1 tripartite motif family-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:48,994,968...49,005,343
Ensembl chr16:48,997,252...49,005,417
JBrowse link
G Triml2 tripartite motif family-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:48,944,838...48,955,453
Ensembl chr16:48,944,838...48,955,453
JBrowse link
G Tspan6 tetraspanin 6 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr  X:97,092,394...97,099,659
Ensembl chr  X:97,092,388...97,099,309
JBrowse link
G Ubd ubiquitin D involved_in IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
(MGI:4821931|PMID:19959714)
GO_REF:0000024
(PMID:19959714)
Ensembl
RGD
UniProt
PMID:19959714 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:4821931, RGD:13792537 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639
JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I acts_upstream_of_or_within ISO (MGI:894913|PMID:9223278) RGD PMID:9223278 MGI:894913 NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N involved_in ISO (PMID:16129784) RGD PMID:16129784 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
JBrowse link
G Ube2v1 ubiquitin conjugating enzyme E2 V1 involved_in ISO (PMID:16129784) RGD PMID:16129784 NCBI chr 3:156,317,339...156,340,198
Ensembl chr 3:156,316,781...156,340,273
JBrowse link
G Unc5cl unc-5 family C-terminal like involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:22158417)
(MGI:5525073|PMID:22158417)
RGD PMID:22158417 PMID:21873635 MGI:5525073, RGD:13792537 NCBI chr 9:12,528,109...12,543,382
Ensembl chr 9:12,528,246...12,542,233
JBrowse link
G Vapa VAMP associated protein A involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 9:105,177,904...105,208,400
Ensembl chr 9:105,177,907...105,207,847
JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 involved_in ISO (PMID:21102435) RGD PMID:21102435 NCBI chr 4:67,012,151...67,062,406
Ensembl chr 4:67,012,185...67,062,428
JBrowse link
G Zdhhc13 zinc finger DHHC-type palmitoyltransferase 13 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 1:98,487,309...98,525,906
Ensembl chr 1:98,487,358...98,525,905
JBrowse link
G Zdhhc17 zinc finger DHHC-type palmitoyltransferase 17 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 7:46,369,963...46,433,691
Ensembl chr 7:46,369,988...46,433,764
JBrowse link
positive regulation of I-kappaB phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:26514923) RGD PMID:26514923 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in ISO
IEA
UniProtKB:P35411 (PMID:10869418)
GO_REF:0000107
RGD
Ensembl
PMID:10869418 GO_REF:0000107 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in IGI PMID:10869418 ARUK-UCL PMID:10869418 RGD:4892026 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:23675531) RGD PMID:23675531 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680
JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in ISO
IEA
(MGI:5300086|PMID:22041900)
GO_REF:0000107
RGD
Ensembl
PMID:22041900 GO_REF:0000107 MGI:5300086 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:31124343) RGD PMID:31124343 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (MGI:5616328|PMID:11374864) RGD PMID:11374864 MGI:5616328 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
regulation of I-kappaB kinase/NF-kappaB signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:98664 (MGI:4437182|PMID:20060382)
Ensembl
RGD
PMID:20060382 GO_REF:0000107 MGI:4437182 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:2669949 (MGI:2668774|PMID:12843402) RGD PMID:12843402 MGI:2668774 NCBI chr 1:244,210,299...244,380,126
Ensembl chr 1:244,210,314...244,376,721
JBrowse link
G Capn3 calpain 3 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5306294|PMID:18073330)
GO_REF:0000107
(PMID:18073330)
UniProt
RGD
Ensembl
PMID:18073330 GO_REF:0000024 GO_REF:0000107 MGI:5306294 NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858
JBrowse link
G Cpne1 copine 1 involved_in ISO
IBA
(PMID:14674885)
PMID:21873635
RGD PMID:14674885 PMID:21873635 RGD:13792537 NCBI chr 3:144,587,548...144,629,603
Ensembl chr 3:144,588,995...144,598,636
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
ISO
GO_REF:0000024
(MGI:4453088|PMID:19948740)
UniProt
RGD
PMID:19948740 GO_REF:0000024 MGI:4453088 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:18453611)
UniProt
RGD
PMID:18453611 GO_REF:0000024 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5050077|PMID:12385642)
Ensembl
RGD
PMID:12385642 GO_REF:0000107 MGI:5050077 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:10748004) RGD PMID:10748004 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Lime1 Lck interacting transmembrane adaptor 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:3769059|PMID:16249387)
PMID:21873635
RGD PMID:16249387 PMID:21873635 MGI:3769059, RGD:13792537 NCBI chr 3:168,490,535...168,496,627
Ensembl chr 3:168,490,074...168,493,127
JBrowse link
G LOC120095693 small ubiquitin-related modifier 2-like involved_in ISO (PMID:15247916), (PMID:18708028) RGD PMID:15247916 PMID:18708028 NCBI chr11:79,163,457...79,164,088
Ensembl chr11:79,163,634...79,163,960
JBrowse link
G Nfkbib NFKB inhibitor beta acts_upstream_of_or_within ISO MGI:1919216 (MGI:6274062|PMID:25220458) RGD PMID:25220458 MGI:6274062 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
G Nkiras2 NFKB inhibitor interacting Ras-like 2 acts_upstream_of_or_within ISO MGI:104752|MGI:6342810 (MGI:6274062|PMID:25220458) RGD PMID:25220458 MGI:6274062 NCBI chr10:85,554,704...85,562,072
Ensembl chr10:85,557,944...85,562,072
JBrowse link
G Nlrp12 NLR family, pyrin domain containing 12 acts_upstream_of_or_within ISO (PMID:12019269) RGD PMID:12019269 NCBI chr 1:65,932,610...65,969,873
Ensembl chr 1:65,932,595...65,960,934
JBrowse link
G Optn optineurin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO (PMID:16207722) RGD PMID:16207722 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Pidd1 p53-induced death domain protein 1 involved_in ISO (PMID:17159900) RGD PMID:17159900 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699
JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 NOT|involved_in ISO (MGI:5305504|PMID:22187458) RGD PMID:22187458 MGI:5305504 NCBI chr 1:240,090,859...240,245,007
Ensembl chr 1:240,093,065...240,204,828
JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in ISO
IEA
(MGI:3844414|PMID:19136564), (MGI:5300086|PMID:22041900)
GO_REF:0000107
RGD
Ensembl
PMID:19136564 PMID:22041900 GO_REF:0000107 MGI:3844414 MGI:5300086 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Rbm12 RNA binding motif protein 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:144,587,548...144,629,950
Ensembl chr 3:144,611,623...144,629,915
JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (MGI:3703830|PMID:17346996) RGD PMID:17346996 MGI:3703830 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391
JBrowse link
G Sqstm1 sequestosome 1 involved_in ISO
ISS
(PMID:12857745)
GO_REF:0000024
RGD
UniProt
PMID:12857745 GO_REF:0000024 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Sumo4 small ubiquitin-like modifier 4 involved_in ISO (PMID:15247916), (PMID:18708028) RGD PMID:15247916 PMID:18708028 NCBI chr 5:15,099,322...15,099,913
Ensembl chr 5:15,099,419...15,099,706
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10748004) RGD PMID:10748004 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
G Traf3 Tnf receptor-associated factor 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:130,199,696...130,307,168
Ensembl chr 6:130,206,484...130,305,481
JBrowse link
G Traf4 Tnf receptor associated factor 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284
JBrowse link
G Traf5 TNF receptor-associated factor 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:103,569,944...103,618,756
Ensembl chr13:103,572,314...103,618,709
JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 5:38,962,721...38,995,134
Ensembl chr 5:38,962,171...38,995,199
JBrowse link
G Wdr83 WD repeat domain 83 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4367006 (MGI:6282238|PMID:29402223)
Ensembl
RGD
PMID:29402223 GO_REF:0000107 MGI:6282238 NCBI chr19:23,076,948...23,082,569
Ensembl chr19:23,077,010...23,082,563
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (MGI:5291547|PMID:21857966) RGD PMID:21857966 MGI:5291547 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
G Zfand6 zinc finger AN1-type containing 6 involved_in ISO
ISS
(PMID:21810480)
GO_REF:0000024
RGD
UniProt
PMID:21810480 GO_REF:0000024 NCBI chr 1:138,581,002...138,652,052
Ensembl chr 1:138,581,002...138,651,939
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    signaling 7370
      signal transduction 6808
        intracellular signal transduction 2667
          I-kappaB kinase/NF-kappaB signaling 292
            I-kappaB phosphorylation + 22
            negative regulation of I-kappaB kinase/NF-kappaB signaling + 54
            positive regulation of I-kappaB kinase/NF-kappaB signaling + 187
            regulation of I-kappaB kinase/NF-kappaB signaling + 257
Path 2
Term Annotations click to browse term
  biological_process 18734
    biological regulation 13314
      regulation of biological process 12594
        regulation of cellular process 11909
          signal transduction 6808
            intracellular signal transduction 2667
              I-kappaB kinase/NF-kappaB signaling 292
                I-kappaB phosphorylation + 22
                negative regulation of I-kappaB kinase/NF-kappaB signaling + 54
                positive regulation of I-kappaB kinase/NF-kappaB signaling + 187
                regulation of I-kappaB kinase/NF-kappaB signaling + 257
paths to the root