Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer VCMap
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:I-kappaB kinase/NF-kappaB signaling
go back to main search page
Accession:GO:0007249 term browser browse the term
Definition:The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.
Synonyms:exact_synonym: I-kappaB kinase/NF-kappaB signal transduction;   NF-kappaB cascade;   canonical NF-kappaB signaling cascade
 related_synonym: I-kappaB kinase/NF-kappaB cascade;   activation of the inhibitor of kappa kinase;   p50-dependent NF-kappaB signaling


show annotations for term's descendants           Sort by:
 
I-kappaB kinase/NF-kappaB signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of
involved_in		 ISO
IEA		 MGI:87860 (MGI:4399009|PMID:18025176)
GO_REF:0000107		 RGD
Ensembl		 PMID:18025176 GO_REF:0000107 MGI:4399009 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of ISO MGI:87859 (MGI:4399009|PMID:18025176) RGD PMID:18025176 MGI:4399009 NCBI chr13:68,673,702...68,839,742
Ensembl chr13:68,673,722...68,839,742 		JBrowse link
G Ajuba ajuba LIM protein acts_upstream_of
involved_in		 ISO
IEA		 (MGI:3581322|PMID:15870274)
GO_REF:0000107		 RGD
Ensembl		 PMID:15870274 GO_REF:0000107 MGI:3581322 NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:26514923) RGD PMID:26514923 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ash1l ASH1 like histone lysine methyltransferase acts_upstream_of ISO (MGI:5562489|PMID:24012418) RGD PMID:24012418 MGI:5562489 NCBI chr 2:174,346,267...174,483,057
Ensembl chr 2:174,346,150...174,483,055 		JBrowse link
G Avpr2 arginine vasopressin receptor 2 acts_upstream_of_or_within ISO MGI:2384212 (MGI:1340165|PMID:10395695) RGD PMID:10395695 MGI:1340165 NCBI chr  X:151,633,501...151,636,000
Ensembl chr  X:151,633,522...151,635,989 		JBrowse link
G Azi2 5-azacytidine induced 2 involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 PMID:21873635
(MGI:1349559|PMID:10580148)
GO_REF:0000107		 RGD
Ensembl		 PMID:10580148 PMID:21873635 GO_REF:0000107 MGI:1349559, RGD:13792537 NCBI chr 8:117,773,248...117,797,844
Ensembl chr 8:117,773,279...117,797,847 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:2158304 (MGI:1930354|PMID:11163238)		 RGD PMID:11163238 PMID:21873635 MGI:1930354, RGD:13792537 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Bcl3 BCL3, transcription coactivator involved_in ISO (PMID:8196632) RGD PMID:8196632 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Btk Bruton tyrosine kinase acts_upstream_of_or_within ISO MGI:1857138 (MGI:2680750|PMID:14597404) RGD PMID:14597404 MGI:2680750 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Card11 caspase recruitment domain family, member 11 involved_in
acts_upstream_of		 ISO (PMID:28628108)
MGI:3039682 (MGI:3039643|PMID:12867038)		 RGD PMID:12867038 PMID:28628108 MGI:3039643 NCBI chr12:13,620,979...13,758,115
Ensembl chr12:13,621,087...13,758,112 		JBrowse link
G Card9 caspase recruitment domain family, member 9 IMP RGD PMID:11053425 RGD:1299399 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Cd74 CD74 molecule involved_in ISO (PMID:23736979) RGD PMID:23736979 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex involved_in
acts_upstream_of		 ISO (PMID:26514923)
MGI:1100089|MGI:3045616 (MGI:3045614|PMID:11747812)		 RGD PMID:11747812 PMID:26514923 MGI:3045614 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of ISO (MGI:4355652|PMID:19619491) RGD PMID:19619491 MGI:4355652 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Defb25 defensin beta 25 involved_in ISO
IBA		 (PMID:24955228)
PMID:21873635		 RGD PMID:24955228 PMID:21873635 RGD:13792537 NCBI chr 3:141,098,856...141,099,696
Ensembl chr 3:141,098,856...141,099,696 		JBrowse link
G Edn1 endothelin 1 involved_in ISO (MGI:6453700|PMID:24722437) RGD PMID:24722437 MGI:6453700 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A involved_in ISO MGI:102720 (MGI:6453700|PMID:24722437) RGD PMID:24722437 MGI:6453700 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Ednrb endothelin receptor type B involved_in ISO MGI:105923 (MGI:6453700|PMID:24722437) RGD PMID:24722437 MGI:6453700 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Faim Fas apoptotic inhibitory molecule involved_in IMP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:15520226 PMID:21873635 RGD:1357927, RGD:13792537 NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase acts_upstream_of ISO MGI:1927596 (MGI:5545939|PMID:23169819) RGD PMID:23169819 MGI:5545939 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B acts_upstream_of ISO MGI:95602 (MGI:5545939|PMID:23169819) RGD PMID:23169819 MGI:5545939 NCBI chr 1:173,316,398...173,340,951
Ensembl chr 1:173,316,907...173,340,932 		JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 acts_upstream_of_or_within ISO (MGI:1859506|PMID:10747961) RGD PMID:10747961 MGI:1859506 NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta involved_in ISO (PMID:15383541), (PMID:25816133) RGD PMID:15383541 PMID:25816133 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il1b interleukin 1 beta acts_upstream_of ISO MGI:1346877 (MGI:3607973|PMID:16260493) RGD PMID:16260493 MGI:3607973 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Irak1bp1 interleukin-1 receptor-associated kinase 1 binding protein 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:1931897|PMID:11096118)		 RGD PMID:11096118 PMID:21873635 MGI:1931897, RGD:13792537 NCBI chr 8:83,731,512...83,748,289
Ensembl chr 8:83,731,507...83,748,289 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602 		JBrowse link
G Irf1 interferon regulatory factor 1 IMP RGD PMID:15141302 RGD:5128786 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G LOC684466 similar to Fas apoptotic inhibitory molecule 1 (rFAIM) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:99,791,849...99,810,206
Ensembl chr 8:99,791,981...99,810,228 		JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 involved_in ISO
IBA		 (MGI:1931349|PMID:11239468)
PMID:21873635		 RGD PMID:11239468 PMID:21873635 MGI:1931349, RGD:13792537 NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of ISO MGI:104798|MGI:2156367|MGI:96536 (MGI:3607973|PMID:16260493) RGD PMID:16260493 MGI:3607973 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of
involved_in		 ISO
IEA		 MGI:2147032|MGI:2385681 (MGI:2669022|PMID:12855817)
GO_REF:0000107		 RGD
Ensembl		 PMID:12855817 GO_REF:0000107 MGI:2669022 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Myo18a myosin XVIIIa involved_in ISO (PMID:9918798) RGD PMID:9918798 NCBI chr10:62,654,218...62,755,464
Ensembl chr10:62,654,281...62,755,468 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:25038658) RGD PMID:25038658 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nfkbil1 NFKB inhibitor like 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:5305914|PMID:22024480)		 RGD PMID:22024480 PMID:21873635 MGI:5305914, RGD:13792537 NCBI chr20:3,589,974...3,608,348
Ensembl chr20:3,590,642...3,605,616 		JBrowse link
G Nkiras2 NFKB inhibitor interacting Ras-like 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:85,554,704...85,562,072
Ensembl chr10:85,557,944...85,562,072 		JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in
acts_upstream_of		 ISS
ISO		 GO_REF:0000024
MGI:108072 (MGI:5437524|PMID:22863753)
(PMID:15705585)		 UniProt
RGD		 PMID:15705585 PMID:22863753 GO_REF:0000024 MGI:5437524 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:3775161|PMID:18261938)
GO_REF:0000107		 RGD
Ensembl		 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:3775161|PMID:18261938)
GO_REF:0000107		 RGD
Ensembl		 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Rel REL proto-oncogene, NF-kB subunit involved_in IMP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:11912207 PMID:21873635 RGD:2300288, RGD:13792537 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 involved_in
acts_upstream_of		 ISO (MGI:5285496|PMID:21469090)
MGI:2446070|MGI:2660793 (MGI:2176422|PMID:11894098), (MGI:2176424|PMID:11894097), (MGI:3775161|PMID:18261938)		 RGD PMID:11894097 PMID:11894098 PMID:18261938 PMID:21469090 MGI:2176422 MGI:2176424 MGI:3775161 MGI:5285496 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 acts_upstream_of_or_within ISO (MGI:1345788|PMID:10490590) RGD PMID:10490590 MGI:1345788 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO
IEA		 (PMID:25816133)
GO_REF:0000107		 RGD
Ensembl		 PMID:25816133 GO_REF:0000107 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO
IEA		 (PMID:25816133)
GO_REF:0000107		 RGD
Ensembl		 PMID:25816133 GO_REF:0000107 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G Snip1 Smad nuclear interacting protein 1 acts_upstream_of_or_within ISO (MGI:2154675|PMID:11567019) RGD PMID:11567019 MGI:2154675 NCBI chr 5:137,328,371...137,335,846
Ensembl chr 5:137,328,371...137,335,845 		JBrowse link
G Tank TRAF family member-associated NFKB activator involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:82296|PMID:8710854)		 RGD PMID:8710854 PMID:21873635 MGI:82296, RGD:13792537 NCBI chr 3:46,114,253...46,190,270
Ensembl chr 3:46,114,274...46,190,264 		JBrowse link
G Tbkbp1 TBK1 binding protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:82,120,558...82,135,749
Ensembl chr10:82,120,564...82,134,352 		JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 acts_upstream_of ISO MGI:108005|MGI:3029019 (MGI:2669022|PMID:12855817) RGD PMID:12855817 MGI:2669022 NCBI chr 9:1,102,559...1,115,573
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tifa TRAF-interacting protein with forkhead-associated domain involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 PMID:21873635
(MGI:2159087|PMID:11798190)
GO_REF:0000002		 RGD
InterPro		 PMID:11798190 PMID:21873635 GO_REF:0000002 MGI:2159087, RGD:13792537 NCBI chr 2:216,257,926...216,267,635
Ensembl chr 2:216,234,774...216,267,841 		JBrowse link
G Tifab TIFA inhibitor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592 		JBrowse link
G Tirap TIR domain containing adaptor protein acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:2152194|PMID:11526399)
PMID:21873635		 RGD PMID:11526399 PMID:21873635 MGI:2152194, RGD:13792537 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of ISO MGI:1346877|MGI:3690535 (MGI:2669022|PMID:12855817), (MGI:3607973|PMID:16260493) RGD PMID:12855817 PMID:16260493 MGI:2669022 MGI:3607973 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of ISO (MGI:3607973|PMID:16260493), (MGI:3775161|PMID:18261938) RGD PMID:16260493 PMID:18261938 MGI:3607973 MGI:3775161 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr8 toll-like receptor 8 involved_in ISO
IBA		 (PMID:12032557)
PMID:21873635		 RGD PMID:12032557 PMID:21873635 RGD:13792537 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in IBA
ISO		 PMID:21873635
(MGI:3826712|PMID:18820679)		 RGD PMID:18820679 PMID:21873635 MGI:3826712, RGD:13792537 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of
involved_in		 ISO
IEA		 MGI:1346877 (MGI:3039643|PMID:12867038), (MGI:3607973|PMID:16260493)
GO_REF:0000107		 RGD
Ensembl		 PMID:12867038 PMID:16260493 GO_REF:0000107 MGI:3039643 MGI:3607973 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:3848090|PMID:19298785)
GO_REF:0000107		 RGD
Ensembl		 PMID:19298785 GO_REF:0000107 MGI:3848090 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 acts_upstream_of_or_within ISO (MGI:2179873|PMID:11390377) RGD PMID:11390377 MGI:2179873 NCBI chr14:76,228,283...76,246,609
Ensembl chr14:76,228,371...76,275,265 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in
acts_upstream_of		 ISO (MGI:4442152|PMID:17633018)
MGI:2444070 (MGI:5437524|PMID:22863753)		 RGD PMID:17633018 PMID:22863753 MGI:4442152 MGI:5437524 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
I-kappaB phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chuk component of inhibitor of nuclear factor kappa B kinase complex involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:4453088|PMID:19948740)		 UniProt
RGD		 PMID:19948740 GO_REF:0000024 MGI:4453088 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 IDA RGD PMID:12133632 RGD:1626124 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762 		JBrowse link
G Erc1 ELKS/RAB6-interacting/CAST family member 1 involved_in ISO
IEA		 (PMID:15218148)
GO_REF:0000107		 RGD
Ensembl		 PMID:15218148 GO_REF:0000107 NCBI chr 4:152,763,664...153,055,706
Ensembl chr 4:152,767,419...153,055,639 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000108
(MGI:3836513|PMID:18981174)		 GOC
RGD		 PMID:18981174 GO_REF:0000108 MGI:3836513 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000108
(MGI:1928258|PMID:10421793)		 GOC
RGD		 PMID:10421793 GO_REF:0000108 MGI:1928258 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:11460167)
MGI:104798|MGI:96536 (MGI:3607973|PMID:16260493)
GO_REF:0000024		 RGD
UniProt		 PMID:11460167 PMID:16260493 GO_REF:0000024 MGI:3607973 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Tlr2 toll-like receptor 2 involved_in ISO (PMID:19740627) RGD PMID:19740627 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr3 toll-like receptor 3 involved_in ISO (PMID:19740627) RGD PMID:19740627 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:19740627)
MGI:1860885 (MGI:3835701|PMID:18820689)
GO_REF:0000107		 RGD
Ensembl		 PMID:18820689 PMID:19740627 GO_REF:0000107 MGI:3835701 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr7 toll-like receptor 7 involved_in ISO (PMID:19740627) RGD PMID:19740627 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (PMID:19740627) RGD PMID:19740627 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Usp25 ubiquitin specific peptidase 25 involved_in ISO MGI:4332130 (MGI:5441108|PMID:23042150) RGD PMID:23042150 MGI:5441108 NCBI chr11:15,603,654...15,711,356
Ensembl chr11:15,603,881...15,711,348 		JBrowse link
negative regulation of I-kappaB kinase/NF-kappaB signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:108086 (MGI:4366111|PMID:19805123) RGD PMID:19805123 MGI:4366111 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO
ISS		 (PMID:10982546)
GO_REF:0000024		 RGD
UniProt		 PMID:10982546 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Ash1l ASH1 like histone lysine methyltransferase acts_upstream_of_or_within ISO (MGI:5562489|PMID:24012418) RGD PMID:24012418 MGI:5562489 NCBI chr 2:174,346,267...174,483,057
Ensembl chr 2:174,346,150...174,483,055 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:26363554) RGD PMID:26363554 NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829 		JBrowse link
G Casp8 caspase 8 involved_in ISO (PMID:17047155) RGD PMID:17047155 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Ccdc22 coiled-coil domain containing 22 involved_in ISO (PMID:23563313) RGD PMID:23563313 NCBI chr  X:14,898,296...14,910,244
Ensembl chr  X:14,898,296...14,910,244 		JBrowse link
G Coro1a coronin 1A involved_in ISO (PMID:25093672) RGD PMID:25093672 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO
ISS		 (PMID:15310755), (PMID:17389591)
GO_REF:0000024		 RGD
UniProt		 PMID:15310755 PMID:17389591 GO_REF:0000024 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 involved_in ISO (PMID:11927590) RGD PMID:11927590 NCBI chr10:10,855,510...10,880,175
Ensembl chr10:10,854,732...10,880,161 		JBrowse link
G Esr1 estrogen receptor 1 involved_in ISO
IEA
ISS		 (PMID:16043358), (PMID:7651415)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:7651415 PMID:16043358 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5009411|PMID:16023107)		 BHF-UCL
RGD		 PMID:16023107 GO_REF:0000024 MGI:5009411 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hdac1 histone deacetylase 1 acts_upstream_of_or_within ISO MGI:87859 (MGI:4366111|PMID:19805123) RGD PMID:19805123 MGI:4366111 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 acts_upstream_of_or_within ISO (MGI:3723275|PMID:17623648) RGD PMID:17623648 MGI:3723275 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:19380766) RGD PMID:19380766 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Mapkbp1 mitogen activated protein kinase binding protein 1 involved_in ISO
IBA		 (PMID:22700971)
PMID:21873635		 RGD PMID:22700971 PMID:21873635 RGD:13792537 NCBI chr 3:106,947,342...106,998,368
Ensembl chr 3:106,947,827...106,996,199 		JBrowse link
G Mir15b microRNA 15b involved_in ISO (PMID:23487264) RGD PMID:23487264 NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297 		JBrowse link
G Mir16 microRNA 16 involved_in ISO (PMID:23487264) RGD PMID:23487264 NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443 		JBrowse link
G Mir195 microRNA 195 involved_in ISO (PMID:23487264) RGD PMID:23487264 NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924 		JBrowse link
G Mir497 microRNA 497 involved_in ISO (PMID:23487264) RGD PMID:23487264 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584 		JBrowse link
G Nfkbid NFKB inhibitor delta acts_upstream_of_or_within ISO (MGI:2177878|PMID:11931770) RGD PMID:11931770 MGI:2177878 NCBI chr 1:85,679,353...85,690,415
Ensembl chr 1:85,680,861...85,690,447 		JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:22863753)
MGI:108072 (MGI:5437524|PMID:22863753)		 RGD PMID:22863753 PMID:21873635 MGI:5437524, RGD:13792537 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398 		JBrowse link
G Nlrp12 NLR family, pyrin domain containing 12 involved_in IBA
ISO		 PMID:21873635
(PMID:16203735)		 RGD PMID:16203735 PMID:21873635 RGD:13792537 NCBI chr 1:65,932,610...65,969,873
Ensembl chr 1:65,932,595...65,960,934 		JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B involved_in ISO (PMID:11551959) RGD PMID:11551959 NCBI chr10:55,838,381...55,904,374
Ensembl chr10:55,843,001...55,912,774 		JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 acts_upstream_of_or_within ISO MGI:5085850 (MGI:5432950|PMID:22763455) RGD PMID:22763455 MGI:5432950 NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113 		JBrowse link
G Nlrx1 NLR family member X1 involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 PMID:21873635
MGI:5141085 (MGI:5050761|PMID:21703540)
GO_REF:0000107		 RGD
Ensembl		 PMID:21703540 PMID:21873635 GO_REF:0000107 MGI:5050761, RGD:13792537 NCBI chr 8:44,588,476...44,606,678
Ensembl chr 8:44,590,048...44,606,484 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:6283959|PMID:30792350)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:30792350 GO_REF:0000024 GO_REF:0000107 MGI:6283959 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO
IEA		 (PMID:21242261)
GO_REF:0000107
(MGI:5707586|PMID:18972444)		 RGD
Ensembl		 PMID:18972444 PMID:21242261 GO_REF:0000107 MGI:5707586 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Olfm4 olfactomedin 4 acts_upstream_of_or_within ISO (MGI:4457946|PMID:20534456) RGD PMID:20534456 MGI:4457946 NCBI chr15:55,385,100...55,429,687
Ensembl chr15:55,407,148...55,429,681 		JBrowse link
G Optn optineurin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3766891|PMID:17702576)		 Ensembl
RGD		 PMID:17702576 GO_REF:0000107 MGI:3766891 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251 		JBrowse link
G Otud7a OTU deubiquitinase 7A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:117,064,428...117,388,217
Ensembl chr 1:117,064,496...117,386,480 		JBrowse link
G Otud7b OTU deubiquitinase 7B involved_in ISO (PMID:11463333)
(MGI:5474156|PMID:23334419)		 RGD PMID:11463333 PMID:23334419 MGI:5474156 NCBI chr 2:183,661,955...183,722,584
Ensembl chr 2:183,662,163...183,718,674 		JBrowse link
G Per1 period circadian regulator 1 involved_in IMP PMID:24447840 UniProt PMID:24447840 RGD:8655527 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431 		JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A involved_in ISO
IEA
IBA
ISS		 (PMID:18930133)
GO_REF:0000107
PMID:21873635
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:18930133 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697 		JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(PMID:18930133)		 UniProt
RGD		 PMID:18930133 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974 		JBrowse link
G Ppm1n protein phosphatase, Mg2+/Mn2+ dependent 1N involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:78,929,350...78,934,435
Ensembl chr 1:78,929,351...78,932,685 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:12486103) RGD PMID:12486103 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rhoa ras homolog family member A IMP RGD PMID:17615156 RGD:1642824 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Rhoh ras homolog family member H involved_in ISO (PMID:11809807) RGD PMID:11809807 NCBI chr14:42,341,135...42,371,971
Ensembl chr14:42,337,751...42,386,369 		JBrowse link
G Riok3 RIO kinase 3 involved_in ISO (PMID:19557502) RGD PMID:19557502 NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (PMID:17047155) RGD PMID:17047155 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Rora RAR-related orphan receptor A involved_in ISO (PMID:11252722) RGD PMID:11252722 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:17680780) RGD PMID:17680780 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 involved_in ISO (PMID:10848577) RGD PMID:10848577 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Tank TRAF family member-associated NFKB activator involved_in ISO (PMID:25861989) RGD PMID:25861989 NCBI chr 3:46,114,253...46,190,270
Ensembl chr 3:46,114,274...46,190,264 		JBrowse link
G Tle1 TLE family member 1, transcriptional corepressor involved_in ISO (PMID:17680780) RGD PMID:17680780 NCBI chr 5:85,851,827...85,934,806
Ensembl chr 5:85,851,827...85,934,774 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:11463333), (PMID:15258597), (PMID:21127049)
(MGI:3777503|PMID:18342009), (MGI:4946158|PMID:21088135)		 RGD PMID:11463333 PMID:15258597 PMID:18342009 PMID:21088135 PMID:21127049 MGI:3777503 MGI:4946158 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 involved_in IBA
ISO		 PMID:21873635
(MGI:5319605|PMID:18212736)
(PMID:16684768)		 RGD PMID:16684768 PMID:18212736 PMID:21873635 MGI:5319605, RGD:13792537 NCBI chr10:39,037,048...39,084,328
Ensembl chr10:39,037,058...39,077,625 		JBrowse link
G Tnip3 TNFAIP3 interacting protein 3 involved_in ISO (PMID:17088249) RGD PMID:17088249 NCBI chr 4:94,867,258...94,908,780
Ensembl chr 4:94,811,097...94,907,605 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6695683|PMID:29663649) RGD PMID:29663649 MGI:6695683 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Trim39 tripartite motif-containing 39 involved_in ISO
IEA
ISS		 (PMID:26363554)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:26363554 GO_REF:0000024 GO_REF:0000107 NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117 		JBrowse link
G Trim59 tripartite motif-containing 59 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:22588174)
(MGI:5426715|PMID:22588174)		 RGD PMID:22588174 PMID:21873635 MGI:5426715, RGD:13792537 NCBI chr 2:153,269,210...153,281,185
Ensembl chr 2:153,268,584...153,281,031 		JBrowse link
G Usp10 ubiquitin specific peptidase 10 involved_in ISO
ISS		 (PMID:25861989)
GO_REF:0000024		 RGD
UniProt		 PMID:25861989 GO_REF:0000024 NCBI chr19:47,972,858...48,014,900
Ensembl chr19:47,972,611...48,014,897 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO		 GO_REF:0000024
(MGI:5142149|PMID:21616078)
(PMID:25861989)		 UniProt
RGD		 PMID:21616078 PMID:25861989 GO_REF:0000024 MGI:5142149 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
G Zmynd11 zinc finger, MYND-type containing 11 involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr17:60,542,669...60,631,913
Ensembl chr17:60,543,077...60,631,902 		JBrowse link
negative regulation of I-kappaB phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir27b microRNA 27b acts_upstream_of_or_within ISO UniProtKB:P01375 (PMID:31124343) RGD PMID:31124343 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Sirpa signal-regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568) RGD PMID:17954568 MGI:3760575 NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098 		JBrowse link
positive regulation of I-kappaB kinase/NF-kappaB signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:87860 (MGI:4399009|PMID:18025176) RGD PMID:18025176 MGI:4399009 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:87859 (MGI:4399009|PMID:18025176) RGD PMID:18025176 MGI:4399009 NCBI chr13:68,673,702...68,839,742
Ensembl chr13:68,673,722...68,839,742 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(MGI:3055867|PMID:14522956), (MGI:3055868|PMID:12087086)		 UniProt
RGD		 PMID:12087086 PMID:14522956 GO_REF:0000024 MGI:3055867 MGI:3055868 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Ajuba ajuba LIM protein acts_upstream_of_or_within ISO (MGI:3581322|PMID:15870274) RGD PMID:15870274 MGI:3581322 NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021 		JBrowse link
G Akap13 A-kinase anchoring protein 13 involved_in ISO
IMP
IBA
ISS		 (PMID:23090968)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:23090968 PMID:23090968 PMID:21873635 GO_REF:0000024, RGD:11059571, RGD:13792537 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646 		JBrowse link
G Alpk1 alpha-kinase 1 involved_in ISO (PMID:28222186), (PMID:28877472), (PMID:30111836) RGD PMID:28222186 PMID:28877472 PMID:30111836 NCBI chr 2:216,126,939...216,247,180
Ensembl chr 2:216,128,825...216,247,157 		JBrowse link
G Ankrd17 ankyrin repeat domain 17 involved_in ISO (PMID:22328336) RGD PMID:22328336 NCBI chr14:17,723,239...17,862,625
Ensembl chr14:17,721,932...17,862,617 		JBrowse link
G Apol3 apolipoprotein L3 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 7:109,288,725...109,297,728
Ensembl chr 7:109,288,725...109,297,723 		JBrowse link
G Atp2c1 ATPase secretory pathway Ca2+ transporting 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 8:106,034,777...106,155,854
Ensembl chr 8:106,034,636...106,156,006 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in ISS
ISO		 GO_REF:0000024
(PMID:12761501), (PMID:18287044), (PMID:27777308)		 UniProt
RGD		 PMID:12761501 PMID:18287044 PMID:27777308 GO_REF:0000024 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Brd4 bromodomain containing 4 involved_in ISO (PMID:19103749) RGD PMID:19103749 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539 		JBrowse link
G Bst2 bone marrow stromal cell antigen 2 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr16:18,217,404...18,220,979
Ensembl chr16:18,217,407...18,220,979 		JBrowse link
G Cant1 calcium activated nucleotidase 1 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr10:103,637,079...103,650,240
Ensembl chr10:103,531,504...103,650,109 		JBrowse link
G Card11 caspase recruitment domain family, member 11 involved_in
acts_upstream_of_or_within		 ISO (PMID:12154360)
(MGI:6695669|PMID:12154356)
MGI:3039682 (MGI:3039643|PMID:12867038)		 RGD PMID:12154356 PMID:12154360 PMID:12867038 MGI:3039643 MGI:6695669 NCBI chr12:13,620,979...13,758,115
Ensembl chr12:13,621,087...13,758,112 		JBrowse link
G Card9 caspase recruitment domain family, member 9 involved_in ISO
IBA		 (PMID:11053425)
PMID:21873635		 RGD PMID:11053425 PMID:21873635 RGD:13792537 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Casp1 caspase 1 involved_in ISO
IEA		 (PMID:12761501), (PMID:15383541)
(MGI:3773087|PMID:16585594)
GO_REF:0000107		 RGD
Ensembl		 PMID:12761501 PMID:15383541 PMID:16585594 GO_REF:0000107 MGI:3773087 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp8 caspase 8 involved_in ISO (PMID:12761501), (PMID:12884866) RGD PMID:12761501 PMID:12884866 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cc2d1a coiled-coil and C2 domain containing 1A involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr19:24,011,897...24,026,937
Ensembl chr19:24,011,938...24,026,936 		JBrowse link
G Ccdc22 coiled-coil domain containing 22 involved_in ISO (PMID:23563313) RGD PMID:23563313 NCBI chr  X:14,898,296...14,910,244
Ensembl chr  X:14,898,296...14,910,244 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:15059845) RGD PMID:15059845 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl21 C-C motif chemokine ligand 21 involved_in ISO (PMID:15059845) RGD PMID:15059845 NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686 		JBrowse link
G Cd36 CD36 molecule acts_upstream_of_or_within ISO MGI:2447190 (MGI:3587138|PMID:16061696) RGD PMID:16061696 MGI:3587138 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd4 Cd4 molecule involved_in ISO (PMID:24942581) RGD PMID:24942581 NCBI chr 4:157,668,878...157,695,366 JBrowse link
G Cd40 CD40 molecule involved_in ISO
IBA		 (PMID:12761501)
PMID:21873635		 RGD PMID:12761501 PMID:21873635 RGD:13792537 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd74 CD74 molecule involved_in ISO (PMID:24942581) RGD PMID:24942581 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex involved_in
acts_upstream_of_or_within		 ISO (PMID:23487264)
MGI:1100089|MGI:3045616 (MGI:3045614|PMID:11747812)		 RGD PMID:11747812 PMID:23487264 MGI:3045614 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Clec4a C-type lectin domain family 4, member A involved_in ISO (MGI:4887333|PMID:17050534) RGD PMID:17050534 MGI:4887333 NCBI chr 4:156,340,439...156,434,212
Ensembl chr 4:156,414,688...156,432,402 		JBrowse link
G Clec4d C-type lectin domain family 4, member D involved_in IEA
ISO		 GO_REF:0000107
(MGI:5562511|PMID:23911656)		 Ensembl
RGD		 PMID:23911656 GO_REF:0000107 MGI:5562511 NCBI chr 4:156,589,591...156,598,969
Ensembl chr 4:156,589,792...156,598,848 		JBrowse link
G Clec4n C-type lectin domain family 4, member n involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr 4:156,539,408...156,558,605 JBrowse link
G Clec6a-ps1 C-type lectin domain family 6, member A, pseudogene 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:156,539,408...156,559,032 JBrowse link
G Cth cystathionine gamma-lyase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5304595|PMID:22244329)		 UniProt
Ensembl
RGD		 PMID:22244329 GO_REF:0000024 GO_REF:0000107 MGI:5304595 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO (MGI:4355652|PMID:19619491) RGD PMID:19619491 MGI:4355652 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in IGI PMID:12729461 ARUK-UCL PMID:12729461 RGD:13673777 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cxxc5 CXXC finger protein 5 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr18:27,427,591...27,458,579
Ensembl chr18:27,427,230...27,458,673 		JBrowse link
G Ddx1 DEAD-box helicase 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5050760|PMID:21703541)		 UniProt
RGD		 PMID:21703541 GO_REF:0000024 MGI:5050760 NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365 		JBrowse link
G Ddx21 DExD-box helicase 21 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5050760|PMID:21703541)		 UniProt
RGD		 PMID:21703541 GO_REF:0000024 MGI:5050760 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543 		JBrowse link
G Dhx15 DEAH-box helicase 15 involved_in ISO (PMID:24990078) RGD PMID:24990078 NCBI chr14:58,787,147...58,825,083
Ensembl chr14:58,787,127...58,825,088 		JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5050760|PMID:21703541)		 UniProt
RGD		 PMID:21703541 GO_REF:0000024 MGI:5050760 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Ecm1 extracellular matrix protein 1 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671 		JBrowse link
G Ect2 epithelial cell transforming 2 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911 		JBrowse link
G Eda ectodysplasin-A acts_upstream_of_or_within ISO MGI:1856197 (MGI:3813383|PMID:18689798) RGD PMID:18689798 MGI:3813383 NCBI chr  X:65,078,454...65,480,172
Ensembl chr  X:65,078,673...65,480,172 		JBrowse link
G Eda2r ectodysplasin A2 receptor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:62,224,763...62,269,344
Ensembl chr  X:62,228,229...62,269,268 		JBrowse link
G Edar ectodysplasin-A receptor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:26,587,836...26,666,543
Ensembl chr20:26,587,839...26,666,494 		JBrowse link
G Eef1d eukaryotic translation elongation factor 1 delta involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799 		JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in ISO
IEA
ISS		 (PMID:12761501)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:12761501 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
ISS		 (PMID:11413129)
GO_REF:0000024		 RGD
UniProt		 PMID:11413129 GO_REF:0000024 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fadd Fas associated via death domain involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Faslg Fas ligand involved_in IBA
ISO		 PMID:21873635
(PMID:12761501)		 RGD PMID:12761501 PMID:21873635 RGD:13792537 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743 		JBrowse link
G Flna filamin A involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO MGI:1927596 (MGI:5545939|PMID:23169819) RGD PMID:23169819 MGI:5545939 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase involved_in ISS
ISO		 GO_REF:0000024
(PMID:23332158)		 UniProt
RGD		 PMID:23332158 GO_REF:0000024 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gja1 gap junction protein, alpha 1 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Golt1b golgi transport 1B involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 4:175,333,056...175,346,156
Ensembl chr 4:175,333,092...175,346,153 		JBrowse link
G Gpr89b G protein-coupled receptor 89B involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 2:184,408,136...184,445,560
Ensembl chr 2:184,401,438...184,445,584 		JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B acts_upstream_of_or_within
involved_in		 ISO MGI:95602 (MGI:5545939|PMID:23169819) RGD PMID:23169819 MGI:5545939 NCBI chr 1:173,316,398...173,340,951
Ensembl chr 1:173,316,907...173,340,932 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in ISO
IEA
ISS		 (PMID:12761501)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:12761501 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:86,735,793...86,756,640
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta involved_in ISO
IEA		 (PMID:30337470)
GO_REF:0000107		 RGD
Ensembl		 PMID:30337470 GO_REF:0000107 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in
acts_upstream_of_or_within		 IBA
ISS
ISO		 PMID:21873635
GO_REF:0000024
(PMID:17702576)
(PMID:18287044)		 UniProt
RGD		 PMID:17702576 PMID:18287044 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499 		JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:15671867 RGD:1358666 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta acts_upstream_of_or_within IDA
ISO		 MGI:1346877 (MGI:3607973|PMID:16260493) RGD PMID:16260493 PMID:15671867 MGI:3607973, RGD:1358666 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 acts_upstream_of_or_within ISO (PMID:22158417) RGD PMID:22158417 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:22158417)		 RGD PMID:22158417 PMID:21873635 RGD:13792537 NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837 		JBrowse link
G Irf3 interferon regulatory factor 3 IMP RGD PMID:20670634 RGD:5128809 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Jmjd8 jumonji domain containing 8 involved_in ISS
ISO		 GO_REF:0000024
(PMID:27671354)		 UniProt
RGD		 PMID:27671354 GO_REF:0000024 NCBI chr10:14,848,965...14,851,881
Ensembl chr10:14,848,980...14,851,879 		JBrowse link
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 involved_in ISO (PMID:21343296) RGD PMID:21343296 NCBI chr 2:194,900,038...194,905,394
Ensembl chr 2:194,900,038...194,905,395 		JBrowse link
G Lgals1 galectin 1 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Litaf lipopolysaccharide-induced TNF factor involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895 		JBrowse link
G Ltbr lymphotoxin beta receptor involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539 		JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:20345905) RGD PMID:20345905 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Lurap1 leucine rich adaptor protein 1 involved_in ISO
IBA		 (PMID:21048106)
PMID:21873635		 RGD PMID:21048106 PMID:21873635 RGD:13792537 NCBI chr 5:129,618,926...129,628,651
Ensembl chr 5:129,614,137...129,628,766 		JBrowse link
G Lurap1l leucine rich adaptor protein 1-like involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:95,362,005...95,409,439
Ensembl chr 5:95,362,005...95,409,438 		JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260 		JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 involved_in ISO (PMID:10094049) RGD PMID:10094049 NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523 		JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of_or_within
involved_in		 IMP
ISO
IBA		 MGI:104798|MGI:2156367|MGI:96536 (MGI:3607973|PMID:16260493)
PMID:21873635
(PMID:14982987)		 RGD PMID:14982987 PMID:16260493 PMID:17947700 PMID:21873635 MGI:3607973, RGD:5508194, RGD:13792537 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Mib2 MIB E3 ubiquitin protein ligase 2 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 5:166,243,776...166,259,944
Ensembl chr 5:166,243,776...166,259,650 		JBrowse link
G Mid2 midline 2 involved_in ISO (PMID:23077300) RGD PMID:23077300 NCBI chr  X:104,354,692...104,456,757
Ensembl chr  X:104,355,316...104,453,473 		JBrowse link
G Mier1 MIER1 transcriptional regulator involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 5:117,876,012...117,927,592
Ensembl chr 5:117,870,382...117,927,589 		JBrowse link
G Mtdh metadherin involved_in ISO (PMID:16452207), (PMID:18316612) RGD PMID:16452207 PMID:18316612 NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within
involved_in		 TAS
ISO		 MGI:2147032|MGI:2385681 (MGI:2669022|PMID:12855817)
(PMID:12761501)		 RGD PMID:12761501 PMID:12855817 PMID:14962484 MGI:2669022, RGD:1302746 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311 		JBrowse link
G Ndfip2 Nedd4 family interacting protein 2 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr15:82,032,366...82,087,043
Ensembl chr15:82,032,366...82,086,317 		JBrowse link
G Nek6 NIMA-related kinase 6 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 3:22,284,269...22,356,302
Ensembl chr 3:22,284,279...22,395,990 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (MGI:3775161|PMID:18261938)
(PMID:10329646)		 RGD PMID:10329646 PMID:18261938 MGI:3775161 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:12527755)
(PMID:11087742)
(MGI:3775161|PMID:18261938)		 RGD PMID:11087742 PMID:12527755 PMID:18261938 PMID:21873635 MGI:3775161, RGD:13792537 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Nup62 nucleoporin 62 involved_in ISO
ISS		 (PMID:10356400)
GO_REF:0000024		 RGD
UniProt		 PMID:10356400 GO_REF:0000024 NCBI chr 1:95,298,995...95,314,902
Ensembl chr 1:95,295,526...95,315,174 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO MGI:4361448 (MGI:4359971|PMID:19734906) RGD PMID:19734906 MGI:4359971 NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285 		JBrowse link
G Pim2 Pim-2 proto-oncogene, serine/threonine kinase involved_in ISO (MGI:3510500|PMID:15548703) RGD PMID:15548703 MGI:3510500 NCBI chr  X:14,617,582...14,622,851
Ensembl chr  X:14,617,582...14,622,851 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:19880420) RGD PMID:19880420 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Plekhg5 pleckstrin homology and RhoGEF domain containing G5 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 5:162,577,999...162,621,518
Ensembl chr 5:162,578,071...162,621,513 		JBrowse link
G Plin3 perilipin 3 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 9:1,111,178...1,123,117
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Plk2 polo-like kinase 2 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697 		JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 1:77,690,203...77,714,507
Ensembl chr 1:77,690,208...77,714,456 		JBrowse link
G Prkcb protein kinase C, beta involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:3626015|PMID:12118249)		 UniProt
Ensembl
RGD		 PMID:12118249 GO_REF:0000024 GO_REF:0000107 MGI:3626015 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Prkce protein kinase C, epsilon acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3609215 (MGI:3609210|PMID:11696589)
GO_REF:0000107		 RGD
Ensembl		 PMID:11696589 GO_REF:0000107 MGI:3609210 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
G Prkd1 protein kinase D1 involved_in ISO
ISS		 (PMID:12505989)
GO_REF:0000024		 RGD
UniProt		 PMID:12505989 GO_REF:0000024 NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS
ISO		 GO_REF:0000024
(PMID:17314283), (PMID:19880420), (PMID:23453807)		 ParkinsonsUK-UCL
RGD		 PMID:17314283 PMID:19880420 PMID:23453807 GO_REF:0000024 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in IEA
ISO
IBA
ISS		 GO_REF:0000107
(MGI:4437982|PMID:19136968)
PMID:21873635
GO_REF:0000024
(PMID:19136968), (PMID:21455173)		 Ensembl
RGD
UniProt		 PMID:19136968 PMID:21455173 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:4437982, RGD:13792537 NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005 		JBrowse link
G Rel REL proto-oncogene, NF-kB subunit involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:12761501)
(MGI:5304595|PMID:22244329)		 RGD PMID:12761501 PMID:22244329 MGI:5304595 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G RGD1562987 similar to cDNA sequence BC031181 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr18:68,586,278...68,594,851
Ensembl chr18:68,586,211...68,596,787 		JBrowse link
G RGD1565355 similar to fatty acid translocase/CD36 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:17,424,749...17,465,808
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Rhoa ras homolog family member A involved_in ISS
ISO		 GO_REF:0000024
(PMID:12761501)		 UniProt
RGD		 PMID:12761501 GO_REF:0000024 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Rhoc ras homolog family member C involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:12761501), (PMID:17389591)
(MGI:5521568|PMID:22089168)		 RGD PMID:12761501 PMID:17389591 PMID:22089168 MGI:5521568 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2446070|MGI:2660793 (MGI:2176422|PMID:11894098), (MGI:2176424|PMID:11894097), (MGI:3775161|PMID:18261938)
PMID:21873635
(PMID:10329646)		 RGD PMID:10329646 PMID:11894097 PMID:11894098 PMID:18261938 PMID:21873635 MGI:2176422 MGI:2176424 MGI:3775161, RGD:13792537 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Rnf31 ring finger protein 31 involved_in ISO (MGI:4462284|PMID:20614026)
(PMID:19136968), (PMID:21455173), (PMID:28481331)		 RGD PMID:19136968 PMID:20614026 PMID:21455173 PMID:28481331 MGI:4462284 NCBI chr15:29,083,047...29,095,328
Ensembl chr15:29,083,631...29,101,915 		JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 involved_in ISO
IBA		 (PMID:27162350)
PMID:21873635		 RGD PMID:27162350 PMID:21873635 RGD:13792537 NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:24942581) RGD PMID:24942581 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G S100a13 S100 calcium binding protein A13 involved_in ISO (PMID:15033494) RGD PMID:15033494 NCBI chr 2:175,999,439...176,005,933 JBrowse link
G S100a4 S100 calcium-binding protein A4 involved_in IBA
ISO		 PMID:21873635
(PMID:15033494)		 RGD PMID:15033494 PMID:21873635 RGD:13792537 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254 		JBrowse link
G S100b S100 calcium binding protein B involved_in IBA
ISO		 PMID:21873635
(PMID:15033494)		 RGD PMID:15033494 PMID:21873635 RGD:13792537 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Sectm1b secreted and transmembrane 1B involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr10:106,325,202...106,333,769
Ensembl chr10:106,325,203...106,333,769 		JBrowse link
G Sharpin SHANK-associated RH domain interactor involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:4947438|PMID:21455180), (MGI:4947439|PMID:21455173)
PMID:21873635
(PMID:21455173)		 UniProt
RGD		 PMID:21455173 PMID:21455180 PMID:21873635 GO_REF:0000024 MGI:4947438 MGI:4947439, RGD:13792537 NCBI chr 7:108,070,681...108,075,012
Ensembl chr 7:108,070,687...108,074,955 		JBrowse link
G Shisa5 shisa family member 5 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 8:109,691,476...109,706,409
Ensembl chr 8:109,691,522...109,706,408 		JBrowse link
G Slc20a1 solute carrier family 20 member 1 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051 		JBrowse link
G Slc35b2 solute carrier family 35 member B2 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 9:15,438,594...15,442,227
Ensembl chr 9:15,438,594...15,442,234 		JBrowse link
G Slc44a2 solute carrier family 44 member 2 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 8:19,870,867...19,905,345
Ensembl chr 8:19,870,888...19,905,342 		JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 involved_in IBA
ISO
ISS		 PMID:21873635
(PMID:12761501), (PMID:15327770), (PMID:22158122)
GO_REF:0000024		 RGD
UniProt		 PMID:12761501 PMID:15327770 PMID:22158122 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:2,375,026...2,424,759
Ensembl chr 1:2,375,490...2,424,756 		JBrowse link
G Tab3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 involved_in IBA
ISO		 PMID:21873635
(PMID:15327770), (PMID:22158122), (PMID:23487264)		 RGD PMID:15327770 PMID:22158122 PMID:23487264 PMID:21873635 RGD:13792537 NCBI chr  X:49,972,414...50,044,658
Ensembl chr  X:49,972,330...50,042,056 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892 		JBrowse link
G Terf2ip TERF2 interacting protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:4821187|PMID:20622870)		 UniProt
RGD		 PMID:20622870 GO_REF:0000024 MGI:4821187 NCBI chr19:39,976,965...39,984,055
Ensembl chr19:39,976,906...39,984,064 		JBrowse link
G Tfg trafficking from ER to golgi regulator involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr11:43,885,542...43,911,976
Ensembl chr11:43,885,661...43,911,976 		JBrowse link
G Tfrc transferrin receptor involved_in ISO (PMID:23016877) RGD PMID:23016877 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tgm2 transglutaminase 2 IMP RGD PMID:15471861 RGD:1579987 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:14982987)
(MGI:5050760|PMID:21703541)
MGI:108005|MGI:3029019 (MGI:2669022|PMID:12855817)		 RGD PMID:12855817 PMID:14982987 PMID:21703541 MGI:2669022 MGI:5050760 NCBI chr 9:1,102,559...1,115,573
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Ticam2 toll-like receptor adaptor molecule 2 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
G Tifa TRAF-interacting protein with forkhead-associated domain involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:26068852), (PMID:28222186), (PMID:28877472), (PMID:30111836)
PMID:21873635		 UniProt
RGD		 PMID:26068852 PMID:28222186 PMID:28877472 PMID:30111836 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:216,257,926...216,267,635
Ensembl chr 2:216,234,774...216,267,841 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO
IBA		 (PMID:19509286)
PMID:21873635		 RGD PMID:19509286 PMID:21873635 RGD:13792537 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of_or_within ISO MGI:1346877|MGI:3690535 (MGI:2669022|PMID:12855817), (MGI:3607973|PMID:16260493), (MGI:4359971|PMID:19734906) RGD PMID:12855817 PMID:16260493 PMID:19734906 MGI:2669022 MGI:3607973 MGI:4359971 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3607973|PMID:16260493), (MGI:3775161|PMID:18261938), (MGI:4359971|PMID:19734906)		 Ensembl
RGD		 PMID:16260493 PMID:18261938 PMID:19734906 GO_REF:0000107 MGI:3607973 MGI:3775161 MGI:4359971 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr6 toll-like receptor 6 acts_upstream_of_or_within ISO (PMID:10231569) RGD PMID:10231569 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (PMID:17128265) RGD PMID:17128265 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tmed4 transmembrane p24 trafficking protein 4 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr14:81,125,049...81,129,665
Ensembl chr14:81,125,053...81,129,631 		JBrowse link
G Tmem101 transmembrane protein 101 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr10:87,105,115...87,108,868
Ensembl chr10:87,105,117...87,108,832 		JBrowse link
G Tmem106a transmembrane protein 106A involved_in ISS
ISO		 GO_REF:0000024
(MGI:6216178|PMID:26215746)		 UniProt
RGD		 PMID:26215746 GO_REF:0000024 MGI:6216178 NCBI chr10:86,506,908...86,515,915
Ensembl chr10:86,506,936...86,515,892 		JBrowse link
G Tmem9b TMEM9 domain family, member B involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 1:163,755,307...163,783,880
Ensembl chr 1:163,764,433...163,783,278 		JBrowse link
G Tnf tumor necrosis factor involved_in
acts_upstream_of_or_within		 IGI
IDA
ISO
IBA		 PMID:12729461
MGI:1346877 (MGI:3039643|PMID:12867038), (MGI:3607973|PMID:16260493), (MGI:5521568|PMID:22089168)
PMID:21873635
(PMID:15310755), (PMID:17922812)		 RGD PMID:12867038 PMID:15310755 PMID:16260493 PMID:17922812 PMID:22089168 More... MGI:3039643 MGI:3607973 MGI:5521568, RGD:1580306, RGD:13673777, RGD:13792537 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf19 TNF receptor superfamily member 19 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:1860663|PMID:10764796)		 RGD PMID:10764796 PMID:21873635 MGI:1860663, RGD:13792537 NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfsf10 TNF superfamily member 10 involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3848090|PMID:19298785)
GO_REF:0000107		 RGD
Ensembl		 PMID:19298785 GO_REF:0000107 MGI:3848090 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO
IBA		 (PMID:21784860)
PMID:21873635		 RGD PMID:21784860 PMID:21873635 RGD:13792537 NCBI chr14:76,228,283...76,246,609
Ensembl chr14:76,228,371...76,275,265 		JBrowse link
G Tradd TNFRSF1A-associated via death domain involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in IBA
ISO		 PMID:21873635
(MGI:5616328|PMID:11374864)		 RGD PMID:11374864 PMID:21873635 MGI:5616328, RGD:13792537 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Traf3ip2 Traf3 interacting protein 2 involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667 		JBrowse link
G Traf5 TNF receptor-associated factor 5 involved_in ISO (PMID:12761501) RGD PMID:12761501 NCBI chr13:103,569,944...103,618,756
Ensembl chr13:103,572,314...103,618,709 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:2444070 (MGI:5437524|PMID:22863753)
(MGI:3054342|PMID:15322147), (MGI:5499721|PMID:20345905)
(PMID:17135271)		 UniProt
RGD		 PMID:15322147 PMID:17135271 PMID:20345905 PMID:22863753 GO_REF:0000024 MGI:3054342 MGI:5437524 MGI:5499721 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trim13 tripartite motif-containing 13 involved_in ISO
IBA		 (PMID:23077300)
PMID:21873635		 RGD PMID:23077300 PMID:21873635 RGD:13792537 NCBI chr15:35,733,548...35,772,676
Ensembl chr15:35,734,107...35,772,677 		JBrowse link
G Trim14 tripartite motif-containing 14 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:60,800,032...60,825,481
Ensembl chr 5:60,800,032...60,824,858 		JBrowse link
G Trim21 tripartite motif-containing 21 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:156,964,896...156,987,504
Ensembl chr 1:156,964,913...156,987,440 		JBrowse link
G Trim25 tripartite motif-containing 25 involved_in ISO (PMID:23077300) RGD PMID:23077300 NCBI chr10:73,812,818...73,831,271
Ensembl chr10:73,812,818...73,831,257 		JBrowse link
G Trim27 tripartite motif-containing 27 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:43,538,282...43,550,633
Ensembl chr17:43,538,285...43,550,643 		JBrowse link
G Trim30 tripartite motif-containing 30 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:158,795,288...158,813,913
Ensembl chr 1:158,720,410...158,814,012 		JBrowse link
G Trim30c tripartite motif-containing 30C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:158,766,401...158,787,915
Ensembl chr 1:158,765,969...158,787,183 		JBrowse link
G Trim32 tripartite motif-containing 32 involved_in ISO (PMID:23077300) RGD PMID:23077300 NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018 		JBrowse link
G Trim34 tripartite motif-containing 34 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:158,707,172...158,720,214
Ensembl chr 1:158,707,172...158,718,674 		JBrowse link
G Trim38 tripartite motif containing 38 involved_in ISO (PMID:23077300) RGD PMID:23077300 NCBI chr17:41,351,857...41,365,021 JBrowse link
G Trim5 tripartite motif-containing 5 involved_in IBA
ISO		 PMID:21873635
(PMID:21512573), (PMID:23077300)		 RGD PMID:21512573 PMID:23077300 PMID:21873635 RGD:13792537 NCBI chr 1:158,720,407...158,737,393
Ensembl chr 1:158,720,410...158,814,012 		JBrowse link
G Trim52 tripartite motif-containing 52 involved_in ISO (PMID:27667714), (PMID:28073078) RGD PMID:27667714 PMID:28073078 NCBI chr15:82,886,237...82,924,611
Ensembl chr15:82,886,237...82,909,759 		JBrowse link
G Trim6 tripartite motif containing 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914 		JBrowse link
G Trim62 tripartite motif-containing 62 involved_in IBA
ISO		 PMID:21873635
(PMID:23077300)		 RGD PMID:23077300 PMID:21873635 RGD:13792537 NCBI chr 5:141,230,830...141,260,629
Ensembl chr 5:141,231,523...141,259,915 		JBrowse link
G Trim68 tripartite motif containing 68 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:157,114,044...157,127,494
Ensembl chr 1:157,114,044...157,127,477 		JBrowse link
G Trim8 tripartite motif-containing 8 involved_in ISO (PMID:23077300) RGD PMID:23077300 NCBI chr 1:245,369,632...245,384,513
Ensembl chr 1:245,369,632...245,384,513 		JBrowse link
G Triml1 tripartite motif family-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:48,994,968...49,005,343
Ensembl chr16:48,997,252...49,005,417 		JBrowse link
G Triml2 tripartite motif family-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:48,944,838...48,955,453
Ensembl chr16:48,944,838...48,955,453 		JBrowse link
G Tspan6 tetraspanin 6 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr  X:97,092,394...97,099,659
Ensembl chr  X:97,092,388...97,099,309 		JBrowse link
G Ubd ubiquitin D involved_in IEA
IBA
ISO
ISS		 GO_REF:0000107
PMID:21873635
(MGI:4821931|PMID:19959714)
GO_REF:0000024
(PMID:19959714)		 Ensembl
RGD
UniProt		 PMID:19959714 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:4821931, RGD:13792537 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639 		JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I acts_upstream_of_or_within ISO (MGI:894913|PMID:9223278) RGD PMID:9223278 MGI:894913 NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443 		JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N involved_in ISO (PMID:16129784) RGD PMID:16129784 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355 		JBrowse link
G Ube2v1 ubiquitin conjugating enzyme E2 V1 involved_in ISO (PMID:16129784) RGD PMID:16129784 NCBI chr 3:156,317,339...156,340,198
Ensembl chr 3:156,316,781...156,340,273 		JBrowse link
G Unc5cl unc-5 family C-terminal like involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:22158417)
(MGI:5525073|PMID:22158417)		 RGD PMID:22158417 PMID:21873635 MGI:5525073, RGD:13792537 NCBI chr 9:12,528,109...12,543,382
Ensembl chr 9:12,528,246...12,542,233 		JBrowse link
G Vapa VAMP associated protein A involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 9:105,177,904...105,208,400
Ensembl chr 9:105,177,907...105,207,847 		JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 involved_in ISO (PMID:21102435) RGD PMID:21102435 NCBI chr 4:67,012,151...67,062,406
Ensembl chr 4:67,012,185...67,062,428 		JBrowse link
G Zdhhc13 zinc finger DHHC-type palmitoyltransferase 13 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 1:98,487,309...98,525,906
Ensembl chr 1:98,487,358...98,525,905 		JBrowse link
G Zdhhc17 zinc finger DHHC-type palmitoyltransferase 17 involved_in ISO (PMID:12761501) UniProt PMID:12761501 NCBI chr 7:46,369,963...46,433,691
Ensembl chr 7:46,369,988...46,433,764 		JBrowse link
positive regulation of I-kappaB phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:26514923) RGD PMID:26514923 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in ISO
IEA		 UniProtKB:P35411 (PMID:10869418)
GO_REF:0000107		 RGD
Ensembl		 PMID:10869418 GO_REF:0000107 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in IGI PMID:10869418 ARUK-UCL PMID:10869418 RGD:4892026 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:23675531) RGD PMID:23675531 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in ISO
IEA		 (MGI:5300086|PMID:22041900)
GO_REF:0000107		 RGD
Ensembl		 PMID:22041900 GO_REF:0000107 MGI:5300086 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:31124343) RGD PMID:31124343 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (MGI:5616328|PMID:11374864) RGD PMID:11374864 MGI:5616328 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
regulation of I-kappaB kinase/NF-kappaB signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:98664 (MGI:4437182|PMID:20060382)		 Ensembl
RGD		 PMID:20060382 GO_REF:0000107 MGI:4437182 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:2669949 (MGI:2668774|PMID:12843402) RGD PMID:12843402 MGI:2668774 NCBI chr 1:244,210,299...244,380,126
Ensembl chr 1:244,210,314...244,376,721 		JBrowse link
G Capn3 calpain 3 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5306294|PMID:18073330)
GO_REF:0000107
(PMID:18073330)		 UniProt
RGD
Ensembl		 PMID:18073330 GO_REF:0000024 GO_REF:0000107 MGI:5306294 NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858 		JBrowse link
G Cpne1 copine 1 involved_in ISO
IBA		 (PMID:14674885)
PMID:21873635		 RGD PMID:14674885 PMID:21873635 RGD:13792537 NCBI chr 3:144,587,548...144,629,603
Ensembl chr 3:144,588,995...144,598,636 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:4453088|PMID:19948740)		 UniProt
RGD		 PMID:19948740 GO_REF:0000024 MGI:4453088 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18453611)		 UniProt
RGD		 PMID:18453611 GO_REF:0000024 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5050077|PMID:12385642)		 Ensembl
RGD		 PMID:12385642 GO_REF:0000107 MGI:5050077 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:10748004) RGD PMID:10748004 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Lime1 Lck interacting transmembrane adaptor 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:3769059|PMID:16249387)
PMID:21873635		 RGD PMID:16249387 PMID:21873635 MGI:3769059, RGD:13792537 NCBI chr 3:168,490,535...168,496,627
Ensembl chr 3:168,490,074...168,493,127 		JBrowse link
G LOC120095693 small ubiquitin-related modifier 2-like involved_in ISO (PMID:15247916), (PMID:18708028) RGD PMID:15247916 PMID:18708028 NCBI chr11:79,163,457...79,164,088
Ensembl chr11:79,163,634...79,163,960 		JBrowse link
G Nfkbib NFKB inhibitor beta acts_upstream_of_or_within ISO MGI:1919216 (MGI:6274062|PMID:25220458) RGD PMID:25220458 MGI:6274062 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862 		JBrowse link
G Nkiras2 NFKB inhibitor interacting Ras-like 2 acts_upstream_of_or_within ISO MGI:104752|MGI:6342810 (MGI:6274062|PMID:25220458) RGD PMID:25220458 MGI:6274062 NCBI chr10:85,554,704...85,562,072
Ensembl chr10:85,557,944...85,562,072 		JBrowse link
G Nlrp12 NLR family, pyrin domain containing 12 acts_upstream_of_or_within ISO (PMID:12019269) RGD PMID:12019269 NCBI chr 1:65,932,610...65,969,873
Ensembl chr 1:65,932,595...65,960,934 		JBrowse link
G Optn optineurin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO (PMID:16207722) RGD PMID:16207722 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Pidd1 p53-induced death domain protein 1 involved_in ISO (PMID:17159900) RGD PMID:17159900 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 NOT|involved_in ISO (MGI:5305504|PMID:22187458) RGD PMID:22187458 MGI:5305504 NCBI chr 1:240,090,859...240,245,007
Ensembl chr 1:240,093,065...240,204,828 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in ISO
IEA		 (MGI:3844414|PMID:19136564), (MGI:5300086|PMID:22041900)
GO_REF:0000107		 RGD
Ensembl		 PMID:19136564 PMID:22041900 GO_REF:0000107 MGI:3844414 MGI:5300086 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Rbm12 RNA binding motif protein 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:144,587,548...144,629,950
Ensembl chr 3:144,611,623...144,629,915 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (MGI:3703830|PMID:17346996) RGD PMID:17346996 MGI:3703830 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
G Sqstm1 sequestosome 1 involved_in ISO
ISS		 (PMID:12857745)
GO_REF:0000024		 RGD
UniProt		 PMID:12857745 GO_REF:0000024 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Sumo4 small ubiquitin-like modifier 4 involved_in ISO (PMID:15247916), (PMID:18708028) RGD PMID:15247916 PMID:18708028 NCBI chr 5:15,099,322...15,099,913
Ensembl chr 5:15,099,419...15,099,706 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10748004) RGD PMID:10748004 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Traf3 Tnf receptor-associated factor 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:130,199,696...130,307,168
Ensembl chr 6:130,206,484...130,305,481 		JBrowse link
G Traf4 Tnf receptor associated factor 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284 		JBrowse link
G Traf5 TNF receptor-associated factor 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:103,569,944...103,618,756
Ensembl chr13:103,572,314...103,618,709 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 5:38,962,721...38,995,134
Ensembl chr 5:38,962,171...38,995,199 		JBrowse link
G Wdr83 WD repeat domain 83 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4367006 (MGI:6282238|PMID:29402223)		 Ensembl
RGD		 PMID:29402223 GO_REF:0000107 MGI:6282238 NCBI chr19:23,076,948...23,082,569
Ensembl chr19:23,077,010...23,082,563 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (MGI:5291547|PMID:21857966) RGD PMID:21857966 MGI:5291547 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Zfand6 zinc finger AN1-type containing 6 involved_in ISO
ISS		 (PMID:21810480)
GO_REF:0000024		 RGD
UniProt		 PMID:21810480 GO_REF:0000024 NCBI chr 1:138,581,002...138,652,052
Ensembl chr 1:138,581,002...138,651,939 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    signaling 7370
      signal transduction 6808
        intracellular signal transduction 2667
          I-kappaB kinase/NF-kappaB signaling 292
            I-kappaB phosphorylation + 22
            negative regulation of I-kappaB kinase/NF-kappaB signaling + 54
            positive regulation of I-kappaB kinase/NF-kappaB signaling + 187
            regulation of I-kappaB kinase/NF-kappaB signaling + 257
Path 2
Term Annotations click to browse term
  biological_process 18734
    biological regulation 13314
      regulation of biological process 12594
        regulation of cellular process 11909
          signal transduction 6808
            intracellular signal transduction 2667
              I-kappaB kinase/NF-kappaB signaling 292
                I-kappaB phosphorylation + 22
                negative regulation of I-kappaB kinase/NF-kappaB signaling + 54
                positive regulation of I-kappaB kinase/NF-kappaB signaling + 187
                regulation of I-kappaB kinase/NF-kappaB signaling + 257
paths to the root