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ONTOLOGY REPORT - ANNOTATIONS


Term:patched ligand maturation
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Accession:GO:0007225 term browser browse the term
Definition:The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups.
Synonyms:exact_synonym: hh protein processing
 narrow_synonym: Hedgehog protein processing
 related_synonym: patched ligand processing



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patched ligand maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Disp1 dispatched RND transporter family member 1 acts_upstream_of_or_within ISO MGI:2429759 (MGI:2389012|PMID:12421714) RGD PMID:12421714 MGI:2389012 NCBI chr13:94,720,928...94,866,702
Ensembl chr13:94,720,928...94,866,702
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19898
    metabolic process 12211
      hormone metabolic process 248
        peptide hormone processing 24
          patched ligand maturation 1
Path 2
Term Annotations click to browse term
  biological_process 19898
    metabolic process 12211
      nitrogen compound metabolic process 10349
        organonitrogen compound metabolic process 7049
          protein metabolic process 6117
            protein maturation 367
              protein processing 275
                signaling receptor ligand precursor processing 30
                  peptide hormone processing 24
                    patched ligand maturation 1
paths to the root