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ONTOLOGY REPORT - ANNOTATIONS

Term:Notch receptor processing
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Accession:GO:0007220 term browser browse the term
Definition:The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor.
Synonyms:exact_synonym: N receptor processing


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Notch receptor processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:126,795,513...126,853,995
Ensembl chr 3:126,795,426...126,853,995 		JBrowse link
G APH1A aph-1 homolog A, gamma-secretase subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20130175) Ensembl
MGI		 PMID:20130175 GO_REF:0000107 NCBI chr 4:98,817,574...98,821,255
Ensembl chr 4:98,817,586...98,821,254 		JBrowse link
G APH1B aph-1 homolog B, gamma-secretase subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:108,549,297...108,763,279
Ensembl chr 1:108,730,298...108,763,401 		JBrowse link
G DNER delta/notch like EGF repeat containing involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15965470) Ensembl
MGI		 PMID:15965470 GO_REF:0000107 NCBI chr15:130,414,159...130,754,043
Ensembl chr15:130,415,061...130,754,048 		JBrowse link
G NCSTN nicastrin involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:90,121,209...90,142,934
Ensembl chr 4:90,119,002...90,142,890 		JBrowse link
G PSEN1 presenilin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10206645), (PMID:20130175)
(PMID:12391611)		 Ensembl
MGI		 PMID:10206645 PMID:12391611 PMID:20130175 GO_REF:0000107 NCBI chr 7:96,478,179...96,567,884
Ensembl chr 7:96,478,190...96,569,130 		JBrowse link
G PSENEN presenilin enhancer, gamma-secretase subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20130175) Ensembl
MGI		 PMID:20130175 GO_REF:0000107 NCBI chr 6:45,171,825...45,174,112
Ensembl chr 6:45,171,825...45,174,102 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17668
    cellular process 17206
      metabolic process 10557
        primary metabolic process 9295
          protein metabolic process 4587
            Notch receptor processing 7
              Notch receptor processing, ligand-dependent 0
              Notch receptor processing, ligand-independent 0
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