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ONTOLOGY REPORT - ANNOTATIONS

Term:Notch receptor processing
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Accession:GO:0007220 term browser browse the term
Definition:The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor.
Synonyms:exact_synonym: N receptor processing


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Notch receptor processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in IDA (PMID:24226769) UniProt PMID:24226769 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732 		JBrowse link
G APH1A aph-1 homolog A, gamma-secretase subunit involved_in
acts_upstream_of_or_within		 IDA
ISO
IBA
NAS
IMP
IEA
TAS		 (PMID:27608597)
(PMID:20130175)
(PMID:10206645)
(PMID:12297508)
(PMID:15274632)		 ARUK-UCL
MGI
GO_Central
ComplexPortal
UniProt
Ensembl
HGNC-UCL		 PMID:10206645 PMID:12297508 PMID:15274632 PMID:20130175 PMID:27608597 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:150,265,404...150,269,016
Ensembl chr 1:150,265,399...150,269,580 		JBrowse link
G APH1B aph-1 homolog B, gamma-secretase subunit involved_in IDA
IBA
NAS		 (PMID:27608597)
(PMID:10206645)		 ARUK-UCL
GO_Central
ComplexPortal		 PMID:10206645 PMID:27608597 GO_REF:0000033 NCBI chr15:63,277,605...63,309,126
Ensembl chr15:63,276,018...63,309,126 		JBrowse link
G DNER delta/notch like EGF repeat containing involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15965470) Ensembl
MGI		 PMID:15965470 GO_REF:0000107 NCBI chr 2:229,357,629...229,714,555
Ensembl chr 2:229,357,629...229,714,555 		JBrowse link
G GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:152,025,674...152,122,340
Ensembl chr 7:152,025,674...152,122,340 		JBrowse link
G NCSTN nicastrin involved_in IMP
IBA
NAS
TAS
IDA		 (PMID:12297508)
(PMID:10206645)
(PMID:15274632)
(PMID:27608597)		 ARUK-UCL
GO_Central
ComplexPortal
HGNC-UCL		 PMID:10206645 PMID:12297508 PMID:15274632 PMID:27608597 GO_REF:0000033 NCBI chr 1:160,343,383...160,358,949
Ensembl chr 1:160,343,294...160,358,952 		JBrowse link
G PSEN1 presenilin 1 involved_in
acts_upstream_of_or_within		 TAS
ISO
IEA
IDA		 (PMID:15274632)
(PMID:10206645), (PMID:20130175)
(PMID:12391611)
(PMID:27608597)		 HGNC-UCL
MGI
Ensembl
ARUK-UCL		 PMID:10206645 PMID:12391611 PMID:15274632 PMID:20130175 PMID:27608597 GO_REF:0000107 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691 		JBrowse link
G PSEN2 presenilin 2 involved_in TAS (PMID:15274632) HGNC-UCL PMID:15274632 NCBI chr 1:226,870,616...226,903,668
Ensembl chr 1:226,870,184...226,927,726 		JBrowse link
G PSENEN presenilin enhancer, gamma-secretase subunit involved_in
acts_upstream_of_or_within		 TAS
ISO
IBA
NAS
IEA		 (PMID:15274632)
(PMID:20130175)
(PMID:10206645)		 HGNC-UCL
MGI
GO_Central
ComplexPortal
Ensembl		 PMID:10206645 PMID:15274632 PMID:20130175 GO_REF:0000033 GO_REF:0000107 NCBI chr19:35,745,651...35,747,519
Ensembl chr19:35,745,600...35,747,519 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19711
    cellular process 18963
      metabolic process 12918
        primary metabolic process 11235
          protein metabolic process 5134
            Notch receptor processing 9
              Notch receptor processing, ligand-dependent 0
              Notch receptor processing, ligand-independent 0
paths to the root