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ONTOLOGY REPORT - ANNOTATIONS

Term:Notch receptor processing
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Accession:GO:0007220 term browser browse the term
Definition:The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor.
Synonyms:exact_synonym: N receptor processing


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Notch receptor processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:9,478,080...9,545,363
Ensembl chr2A:9,641,201...9,708,054 		JBrowse link
G APH1A aph-1 homolog A, gamma-secretase subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20130175) Ensembl
MGI		 PMID:20130175 GO_REF:0000107 NCBI chr 1:125,610,649...125,614,261
Ensembl chr 1:129,262,002...129,265,810 		JBrowse link
G APH1B aph-1 homolog B, gamma-secretase subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:42,224,593...42,256,202
Ensembl chr15:60,520,031...60,551,599 		JBrowse link
G DNER delta/notch like EGF repeat containing involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15965470) Ensembl
MGI		 PMID:15965470 GO_REF:0000107 NCBI chr2B:116,604,193...116,963,026
Ensembl chr2B:235,409,108...235,642,161 		JBrowse link
G NCSTN nicastrin involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:135,697,592...135,713,293
Ensembl chr 1:139,618,229...139,633,911 		JBrowse link
G PSEN1 presenilin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12391611)
(PMID:10206645), (PMID:20130175)		 Ensembl
MGI		 PMID:10206645 PMID:12391611 PMID:20130175 GO_REF:0000107 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876 		JBrowse link
G PSENEN presenilin enhancer, gamma-secretase subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20130175) Ensembl
TreeGrafter
MGI		 PMID:20130175 GO_REF:0000107 GO_REF:0000118 NCBI chr19:32,675,331...32,677,285
Ensembl chr19:41,409,662...41,411,089 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16643
    cellular process 16206
      metabolic process 10770
        primary metabolic process 9466
          protein metabolic process 4592
            Notch receptor processing 7
              Notch receptor processing, ligand-dependent 0
              Notch receptor processing, ligand-independent 0
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