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ONTOLOGY REPORT - ANNOTATIONS


Term:Notch receptor processing
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Accession:GO:0007220 term browser browse the term
Definition:The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor.
Synonyms:exact_synonym: N receptor processing



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Notch receptor processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:24226769)
UniProt
Ensembl
RGD
PMID:24226769 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Aph1a aph-1 homolog A, gamma secretase subunit involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:12297508), (PMID:27608597)
PMID:21873635
(MGI:4437371|PMID:20130175)
RGD PMID:12297508 PMID:20130175 PMID:27608597 PMID:21873635 MGI:4437371, RGD:13792537 NCBI chr 2:183,437,676...183,443,113
Ensembl chr 2:183,438,434...183,441,955
JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit involved_in IBA
ISO
PMID:21873635
(PMID:27608597)
RGD PMID:27608597 PMID:21873635 RGD:13792537 NCBI chr 8:67,429,198...67,454,735
Ensembl chr 8:67,429,198...67,450,243
JBrowse link
G Dner delta/notch-like EGF repeat containing acts_upstream_of_or_within ISO (MGI:3583881|PMID:15965470) RGD PMID:15965470 MGI:3583881 NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:85,586,987...85,902,637
JBrowse link
G Galnt11 polypeptide N-acetylgalactosaminyltransferase 11 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:9,837,629...9,871,141
Ensembl chr 4:9,837,629...9,871,140
JBrowse link
G Ncstn nicastrin involved_in ISO
IBA
(PMID:12297508), (PMID:27608597)
PMID:21873635
RGD PMID:12297508 PMID:27608597 PMID:21873635 RGD:13792537 NCBI chr13:84,530,442...84,546,454
Ensembl chr13:84,530,440...84,546,454
JBrowse link
G Psen1 presenilin 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2149116|MGI:3051523 (MGI:1334955|PMID:10206645), (MGI:3051409|PMID:12391611), (MGI:4437371|PMID:20130175)
(PMID:27608597)
RGD PMID:10206645 PMID:12391611 PMID:20130175 PMID:27608597 PMID:21873635 MGI:1334955 MGI:3051409 MGI:4437371, RGD:13792537 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Psen2 presenilin 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Psenen presenilin enhancer gamma secretase subunit acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:4437371|PMID:20130175)
PMID:21873635
RGD PMID:20130175 PMID:21873635 MGI:4437371, RGD:13792537 NCBI chr 1:85,814,905...85,816,654
Ensembl chr 1:85,814,905...85,816,192
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19574
    metabolic process 11556
      primary metabolic process 9996
        protein metabolic process 4654
          Notch receptor processing 9
            Notch receptor processing, ligand-dependent 0
            Notch receptor processing, ligand-independent 0
Path 2
Term Annotations click to browse term
  biological_process 19574
    metabolic process 11556
      organic substance metabolic process 10908
        macromolecule metabolic process 9179
          protein metabolic process 4654
            Notch receptor processing 9
              Notch receptor processing, ligand-dependent 0
              Notch receptor processing, ligand-independent 0
paths to the root