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ONTOLOGY REPORT - ANNOTATIONS

Term:gamma-aminobutyric acid signaling pathway
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Accession:GO:0007214 term browser browse the term
Definition:The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to its receptor on the surface of a target cell.
Synonyms:exact_synonym: 4-aminobutanoate signaling pathway;   4-aminobutanoate signalling pathway;   4-aminobutyrate signaling pathway;   4-aminobutyrate signalling pathway;   GABA signaling pathway;   GABA signalling pathway;   gamma-aminobutyric acid signalling pathway


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gamma-aminobutyric acid signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 ISO RGD PMID:10924501 RGD:631878 NCBI chr10:25,528,880...25,531,018
Ensembl chr10:25,528,874...25,530,993 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 acts_upstream_of_or_within ISO (PMID:27549929) MGI PMID:27549929 NCBI chr 1:112,325,988...112,346,056
Ensembl chr 1:112,325,289...112,346,916 		JBrowse link
G BDNF brain derived neurotrophic factor acts_upstream_of_or_within ISO (PMID:16754670) MGI PMID:16754670 NCBI chr21:48,191,580...48,243,699
Ensembl chr21:48,192,670...48,204,480 		JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A acts_upstream_of_or_within ISO (PMID:8565963) MGI PMID:8565963 NCBI chr20:48,747,087...49,036,627
Ensembl chr20:48,821,025...49,036,032 		JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:52,987,170...53,116,410
Ensembl chr19:52,993,618...53,116,140
Ensembl chr19:52,993,618...53,116,140 		JBrowse link
G CIT citron rho-interacting serine/threonine kinase ISO RGD PMID:9870942 RGD:70684 NCBI chr26:15,721,500...15,885,133
Ensembl chr26:15,723,690...15,884,343 		JBrowse link
G GABBR1 gamma-aminobutyric acid type B receptor subunit 1 involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr35:26,212,274...26,243,910
Ensembl chr35:26,213,076...26,237,572 		JBrowse link
G GABBR2 gamma-aminobutyric acid type B receptor subunit 2 involved_in ISO
IEA
IBA		 RGD
Ensembl
GO_Central		 PMID:11389174 GO_REF:0000033 GO_REF:0000107 RGD:632824 NCBI chr11:55,469,327...55,817,930
Ensembl chr11:55,470,197...55,817,945 		JBrowse link
G GABRA1 gamma-aminobutyric acid type A receptor subunit alpha1 involved_in IEA
IBA		 InterPro
Ensembl
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:49,006,981...49,065,205
Ensembl chr 4:49,009,495...49,062,581 		JBrowse link
G GABRA2 gamma-aminobutyric acid type A receptor subunit alpha2 involved_in IEA
IBA		 InterPro
Ensembl
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr13:42,367,988...42,488,069
Ensembl chr13:42,368,949...42,488,075 		JBrowse link
G GABRA3 gamma-aminobutyric acid type A receptor subunit alpha3 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr  X:120,152,650...120,460,604
Ensembl chr  X:120,153,261...120,460,119 		JBrowse link
G GABRA4 gamma-aminobutyric acid type A receptor subunit alpha4 involved_in IEA
IBA		 InterPro
Ensembl
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr13:42,889,100...42,958,604
Ensembl chr13:42,897,655...42,959,206 		JBrowse link
G GABRA5 gamma-aminobutyric acid type A receptor subunit alpha5 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 3:33,663,414...33,746,120
Ensembl chr 3:33,664,169...33,744,328 		JBrowse link
G GABRA6 gamma-aminobutyric acid type A receptor subunit alpha6 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:49,208,691...49,225,754
Ensembl chr 4:49,208,605...49,226,212 		JBrowse link
G GABRB1 gamma-aminobutyric acid type A receptor subunit beta1 involved_in ISO (PMID:26950270) UniProt PMID:26950270 NCBI chr13:43,011,491...43,349,876
Ensembl chr13:42,992,569...43,349,923 		JBrowse link
G GABRB2 gamma-aminobutyric acid type A receptor subunit beta2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:49,342,527...49,579,697
Ensembl chr 4:49,342,508...49,578,092 		JBrowse link
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:33,878,948...34,101,987
Ensembl chr 3:33,878,904...34,097,764 		JBrowse link
G GABRD gamma-aminobutyric acid type A receptor subunit delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:56,984,786...56,994,790
Ensembl chr 5:56,984,913...56,994,358 		JBrowse link
G GABRE gamma-aminobutyric acid type A receptor subunit epsilon involved_in ISO
IBA		 RGD
GO_Central		 PMID:11691872 GO_REF:0000033 RGD:727328 NCBI chr  X:119,913,867...119,937,867
Ensembl chr  X:119,913,867...119,937,909 		JBrowse link
G GABRG1 gamma-aminobutyric acid type A receptor subunit gamma1 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr13:42,194,929...42,276,379
Ensembl chr13:42,200,202...42,276,711 		JBrowse link
G GABRG2 gamma-aminobutyric acid type A receptor subunit gamma2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:12574411) InterPro
Ensembl
MGI
GO_Central		 PMID:12574411 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:48,794,770...48,901,859
Ensembl chr 4:48,796,852...48,901,548 		JBrowse link
G GABRG3 gamma-aminobutyric acid type A receptor subunit gamma3 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 3:32,956,061...33,641,971
Ensembl chr 3:32,964,122...33,642,686 		JBrowse link
G GABRR1 gamma-aminobutyric acid type A receptor subunit rho1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:48,431,273...48,465,426
Ensembl chr12:48,431,379...48,538,037 		JBrowse link
G GABRR2 gamma-aminobutyric acid type A receptor subunit rho2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:48,492,607...48,537,961
Ensembl chr12:48,431,379...48,538,037 		JBrowse link
G GNAI2 G protein subunit alpha i2 involved_in ISO
IBA		 RGD
GO_Central		 PMID:11923410 GO_REF:0000033 RGD:625670 NCBI chr20:39,075,085...39,094,697
Ensembl chr20:39,075,085...39,094,697 		JBrowse link
G GPR156 G protein-coupled receptor 156 involved_in IBA GO_Central GO_REF:0000033 NCBI chr33:23,720,883...23,804,289
Ensembl chr33:23,722,672...23,774,283 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A acts_upstream_of_or_within ISO (PMID:16925594) MGI PMID:16925594 NCBI chr 2:50,005,277...50,006,548
Ensembl chr 2:50,002,740...50,006,548 		JBrowse link
G HTR4 5-hydroxytryptamine receptor 4 ISO RGD PMID:11986365 RGD:727368 NCBI chr 4:60,224,534...60,359,244
Ensembl chr 4:60,185,056...60,353,439 		JBrowse link
G PHF24 PHD finger protein 24 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:51,552,345...51,580,762
Ensembl chr11:51,569,770...51,577,059 		JBrowse link
G PIANP PILR alpha associated neural protein acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr27:38,339,720...38,342,900
Ensembl chr27:38,341,011...38,343,572 		JBrowse link
G PLCL1 phospholipase C like 1 (inactive) involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr37:7,235,403...7,575,429
Ensembl chr37:7,235,424...7,562,708 		JBrowse link
G PLCL2 phospholipase C like 2 involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr23:25,814,392...25,999,666
Ensembl chr23:25,814,862...25,999,749 		JBrowse link
G SHISA7 shisa family member 7 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:102,260,917...102,270,388
Ensembl chr 1:102,261,484...102,268,179 		JBrowse link
G SLC12A2 solute carrier family 12 member 2 acts_upstream_of_or_within ISO PMID:16227993 RGD
ARUK-UCL		 PMID:15090604 PMID:16227993 RGD:1580436 RGD:1580584 NCBI chr11:17,143,943...17,256,248
Ensembl chr11:17,143,943...17,253,695 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22141
    cellular process 21672
      cell communication 6982
        cell-cell signaling 1470
          gamma-aminobutyric acid signaling pathway 34
            extrasynaptic signaling via GABA 0
Path 2
Term Annotations click to browse term
  biological_process 22141
    biological regulation 12559
      regulation of biological process 12176
        signaling 6948
          cell-cell signaling 1470
            gamma-aminobutyric acid signaling pathway 34
              extrasynaptic signaling via GABA 0
paths to the root