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ONTOLOGY REPORT - ANNOTATIONS

Term:gamma-aminobutyric acid signaling pathway
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Accession:GO:0007214 term browser browse the term
Definition:The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to its receptor on the surface of a target cell.
Synonyms:exact_synonym: 4-aminobutanoate signaling pathway;   4-aminobutanoate signalling pathway;   4-aminobutyrate signaling pathway;   4-aminobutyrate signalling pathway;   GABA signaling pathway;   GABA signalling pathway;   gamma-aminobutyric acid signalling pathway


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gamma-aminobutyric acid signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 IDA RGD PMID:10924501 RGD:631878 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Bdnf brain-derived neurotrophic factor acts_upstream_of_or_within ISO (MGI:3694324|PMID:16754670) RGD PMID:16754670 MGI:3694324 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A acts_upstream_of_or_within ISO MGI:1856209 (MGI:79685|PMID:8565963) RGD PMID:8565963 MGI:79685 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 acts_upstream_of_or_within ISO MGI:1856936 (MGI:52881|PMID:8388308), (MGI:77305|PMID:7472490), (MGI:77739|PMID:7562514) RGD PMID:7472490 PMID:7562514 PMID:8388308 MGI:52881 MGI:77305 MGI:77739 NCBI chr 3:36,906,771...37,169,191
Ensembl chr 3:36,910,427...37,168,944 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 involved_in
acts_upstream_of_or_within		 ISS
IBA
IDA
ISO		 GO_REF:0000024
PMID:21873635
PMID:15147298
(PMID:987231), (PMID:9872316)
(MGI:4462115|PMID:20400944)		 UniProt
RGD		 PMID:987231 PMID:9872316 PMID:20400944 PMID:21873635 PMID:15147298 GO_REF:0000024 MGI:4462115, RGD:13792537, RGD:2315493 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 involved_in IDA
IBA
ISO
IEA		 PMID:21873635
PMID:15147298
(PMID:987231), (PMID:9872316)
GO_REF:0000107		 RGD
Ensembl		 PMID:987231 PMID:9872316 PMID:11389174 PMID:21873635 PMID:15147298 GO_REF:0000107, RGD:632824, RGD:13792537, RGD:2315493 NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104 		JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 involved_in ISO
IBA		 (PMID:29950725), (PMID:30602789)
PMID:21873635		 RGD PMID:29950725 PMID:30602789 PMID:21873635 RGD:13792537 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864 		JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 involved_in IEA
IBA
ISO		 GO_REF:0000002
PMID:21873635
GO_REF:0000107
(PMID:8391122)		 InterPro
Ensembl
RGD		 PMID:8391122 PMID:21873635 GO_REF:0000002 GO_REF:0000107, RGD:13792537 NCBI chr14:37,096,995...37,230,030
Ensembl chr14:37,097,279...37,228,944 		JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:150,244,745...150,501,566
Ensembl chr  X:150,261,607...150,501,559 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844 		JBrowse link
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:108,268,728...108,381,670
Ensembl chr 1:108,268,776...108,380,917 		JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 involved_in IEA
IBA		 GO_REF:0000002
PMID:21873635		 InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr10:26,810,411...26,825,768
Ensembl chr10:26,810,423...26,825,769 		JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 involved_in TAS
ISO
ISS		 (PMID:26950270)
GO_REF:0000024		 RGD
UniProt		 PMID:26950270 PMID:11986365 GO_REF:0000024, RGD:727368 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948 		JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 involved_in TAS
ISO		 (PMID:27789573), (PMID:29950725) RGD PMID:27789573 PMID:29950725 PMID:11877425 RGD:727351 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:26950270), (PMID:30602789)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:26950270 PMID:30602789 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961 		JBrowse link
G Gabre gamma-aminobutyric acid type A receptor subunit epsilon involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:11691872 PMID:21873635 RGD:727328, RGD:13792537 NCBI chr  X:150,060,035...150,078,773
Ensembl chr  X:150,060,040...150,078,693 		JBrowse link
G Gabrg1 gamma-aminobutyric acid type A receptor subunit gamma 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:37,396,217...37,469,606
Ensembl chr14:37,396,294...37,635,956 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 involved_in
acts_upstream_of_or_within		 TAS
IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(PMID:29950725), (PMID:30602789)
(MGI:2450227|PMID:12574411)		 Ensembl
RGD		 PMID:12574411 PMID:29950725 PMID:30602789 PMID:1702644 PMID:21873635 GO_REF:0000107 MGI:2450227, RGD:728419, RGD:13792537 NCBI chr10:26,376,805...26,463,680
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Gabrg3 gamma-aminobutyric acid type A receptor subunit gamma 3 involved_in TAS
IBA
IEA		 PMID:21873635
GO_REF:0000002		 InterPro
RGD		 PMID:1311098 PMID:21873635 GO_REF:0000002, RGD:727524, RGD:13792537 NCBI chr 1:107,627,450...108,247,483
Ensembl chr 1:107,627,390...108,246,763 		JBrowse link
G Gabrr2 gamma-aminobutyric acid type A receptor subunit rho 2 acts_upstream_of_or_within ISO MGI:2446461 (MGI:2179933|PMID:12019334) RGD PMID:12019334 MGI:2179933 NCBI chr 5:47,445,280...47,489,929
Ensembl chr 5:47,452,150...47,489,809 		JBrowse link
G Gnai2 G protein subunit alpha i2 involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:11923410 PMID:21873635 RGD:625670, RGD:13792537 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gpr156 G protein-coupled receptor 156 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:62,723,464...62,815,444
Ensembl chr11:62,723,872...62,815,435 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A acts_upstream_of_or_within ISO MGI:2387408 (MGI:3830611|PMID:16925594) RGD PMID:16925594 MGI:3830611 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 IMP RGD PMID:11986365 RGD:727368 NCBI chr18:55,765,981...55,949,921
Ensembl chr18:55,766,725...55,949,321 		JBrowse link
G Phf24 PHD finger protein 24 acts_upstream_of_or_within ISO MGI:5706936 (MGI:5616490|PMID:25242222) RGD PMID:25242222 MGI:5616490 NCBI chr 5:57,143,428...57,171,054
Ensembl chr 5:57,142,632...57,168,497 		JBrowse link
G Plcl1 phospholipase C-like 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1352756 (MGI:3694324|PMID:16754670)		 Ensembl
RGD		 PMID:16754670 GO_REF:0000107 MGI:3694324 NCBI chr 9:56,901,573...57,238,782
Ensembl chr 9:56,901,534...57,238,782 		JBrowse link
G Plcl2 phospholipase C-like 2 acts_upstream_of_or_within ISO MGI:3036262 (MGI:3694324|PMID:16754670) RGD PMID:16754670 MGI:3694324 NCBI chr 9:3,292,564...3,477,009
Ensembl chr 9:3,292,695...3,477,009 		JBrowse link
G Shisa7 shisa family member 7 involved_in ISO (MGI:6377643|PMID:31601770) RGD PMID:31601770 MGI:6377643 NCBI chr 1:68,993,900...69,012,943
Ensembl chr 1:68,994,025...69,012,943 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 acts_upstream_of_or_within IEP
IMP		 PMID:16227993 RGD
ARUK-UCL		 PMID:15090604 PMID:16227993 RGD:1580436, RGD:1580584 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    signaling 7370
      cell-cell signaling 1766
        gamma-aminobutyric acid signaling pathway 29
          extrasynaptic signaling via GABA 0
Path 2
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      cell communication 7465
        cell-cell signaling 1766
          gamma-aminobutyric acid signaling pathway 29
            extrasynaptic signaling via GABA 0
paths to the root