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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:G protein-coupled acetylcholine receptor signaling pathway
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Accession:GO:0007213 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway initiated by a ligand binding to an acetylcholine receptor on the surface of a target cell, and ends with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: acetylcholine receptor signalling, muscarinic pathway;   muscarinic acetylcholine receptor signaling pathway


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G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5r1 cyclin dependent kinase 5, regulatory subunit 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr11:80,367,849...80,372,010
Ensembl chr11:80,367,849...80,372,010 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS involved_in ISO RGD
MGI		 PMID:12534975 GO_REF:0000096 MGI:4417868 RGD:724727 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2, cardiac involved_in
acts_upstream_of_or_within		 ISO
IMP		 (PMID:9990086) RGD
MGI		 PMID:9990086 PMID:12534975 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:724727 NCBI chr 6:36,364,928...36,505,573
Ensembl chr 6:36,365,019...36,505,349 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3, cardiac involved_in ISO RGD
MGI		 PMID:12185001 PMID:15141107 GO_REF:0000096 MGI:4417868 RGD:2303392 RGD:724728 NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883 		JBrowse link
G Gnai2 G protein subunit alpha i2 acts_upstream_of_or_within IMP (PMID:11299198) MGI PMID:11299198 NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566 		JBrowse link
G Plcb1 phospholipase C, beta 1 involved_in IMP (MGI:1097045|PMID:9305844) BHF-UCL PMID:9305844 MGI:1097045 NCBI chr 2:134,628,084...135,317,178
Ensembl chr 2:134,627,987...135,317,178 		JBrowse link
G Rgs10 regulator of G-protein signalling 10 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:127,975,345...128,020,993
Ensembl chr 7:127,975,345...128,020,482 		JBrowse link
G Rgs8 regulator of G-protein signaling 8 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 1:153,528,612...153,573,415
Ensembl chr 1:153,528,771...153,576,069 		JBrowse link
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm1 cholinergic receptor, muscarinic 1, CNS involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2, cardiac involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:36,364,928...36,505,573
Ensembl chr 6:36,365,019...36,505,349 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3, cardiac involved_in IBA GO_Central GO_REF:0000033 NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 involved_in
acts_upstream_of_or_within		 IBA
IDA		 (PMID:7916637) GO_Central
MGI		 PMID:7916637 GO_REF:0000033 NCBI chr 2:91,752,531...91,760,180
Ensembl chr 2:91,757,594...91,759,033 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:112,306,055...112,365,487
Ensembl chr 2:112,309,516...112,311,114 		JBrowse link
G Hrh3 histamine receptor H3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:179,741,258...179,746,264
Ensembl chr 2:179,741,258...179,746,281 		JBrowse link
G Hrh4 histamine receptor H4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr18:13,140,039...13,156,758
Ensembl chr18:13,140,047...13,155,939 		JBrowse link
G Oprm1 opioid receptor, mu 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr10:6,708,593...6,988,209
Ensembl chr10:6,708,506...6,988,198 		JBrowse link
phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa7 annexin A7 acts_upstream_of_or_within_positive_effect IMP (PMID:10570150) MGI PMID:10570150 NCBI chr14:20,505,344...20,530,009
Ensembl chr14:20,505,328...20,530,201 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3, cardiac involved_in IMP
IDA		 (PMID:16753580)
(PMID:20440069)		 MGI PMID:16753580 PMID:20440069 NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883 		JBrowse link
G Gna11 guanine nucleotide binding protein, alpha 11 involved_in IGI (PMID:20440069) MGI PMID:20440069 NCBI chr10:81,364,558...81,380,996
Ensembl chr10:81,364,558...81,381,024 		JBrowse link
G Gnaq guanine nucleotide binding protein, alpha q polypeptide involved_in IGI (PMID:20440069) MGI PMID:20440069 NCBI chr19:16,110,048...16,365,884
Ensembl chr19:16,110,195...16,364,827 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor 1 involved_in IGI (PMID:10570150) MGI PMID:10570150 NCBI chr 6:108,190,044...108,528,077
Ensembl chr 6:108,190,057...108,528,070 		JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 involved_in ISO (PMID:26494622) MGI PMID:26494622 NCBI chr 5:123,153,078...123,168,515
Ensembl chr 5:123,153,137...123,168,519 		JBrowse link
G Plcb1 phospholipase C, beta 1 involved_in IGI
IMP		 (PMID:10570150)
(PMID:31268747)		 MGI PMID:10570150 PMID:31268747 NCBI chr 2:134,628,084...135,317,178
Ensembl chr 2:134,627,987...135,317,178 		JBrowse link
G Prkcb protein kinase C, beta involved_in IDA (PMID:27226533) MGI PMID:27226533 NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625 		JBrowse link
G Stim1 stromal interaction molecule 1 involved_in IDA (PMID:18452988) MGI PMID:18452988 NCBI chr 7:101,909,279...102,086,525
Ensembl chr 7:101,917,013...102,086,526 		JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 involved_in ISO (PMID:26494622) MGI PMID:26494622 NCBI chr 9:95,587,125...95,632,438
Ensembl chr 9:95,587,135...95,632,428 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    cellular process 17545
      signal transduction 6675
        G protein-coupled receptor signaling pathway 2029
          G protein-coupled acetylcholine receptor signaling pathway 21
            G protein-coupled acetylcholine receptor signaling pathway involved in heart process + 0
            G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission 0
            adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway 8
            phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway 10
Path 2
Term Annotations click to browse term
  biological_process 28573
    biological regulation 13118
      regulation of biological process 12727
        signaling 7288
          cell-cell signaling 1508
            synaptic signaling 1025
              postsynaptic signal transduction 71
                acetylcholine receptor signaling pathway 53
                  G protein-coupled acetylcholine receptor signaling pathway 21
                    G protein-coupled acetylcholine receptor signaling pathway involved in heart process + 0
                    G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission 0
                    adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway 8
                    phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway 10
paths to the root