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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:G protein-coupled acetylcholine receptor signaling pathway
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Accession:GO:0007213 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway initiated by a ligand binding to an acetylcholine receptor on the surface of a target cell, and ends with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: acetylcholine receptor signalling, muscarinic pathway;   muscarinic acetylcholine receptor signaling pathway


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G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 involved_in ISO PMID:11276227 UniProt PMID:11276227 RGD:8554712 NCBI chr17:24,285,069...24,289,311
Ensembl chr17:24,577,537...24,579,232 		JBrowse link
G CHRM1 cholinergic receptor muscarinic 1 involved_in ISO (PMID:12196552) RGD
AgBase		 PMID:12196552 PMID:12534975 RGD:724727 NCBI chr11:58,261,476...58,274,685
Ensembl chr11:61,614,818...61,616,200 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9990086) RGD
MGI
Ensembl		 PMID:9990086 PMID:12534975 GO_REF:0000107 RGD:724727 NCBI chr 7:128,827,089...128,978,496
Ensembl chr 7:141,466,396...141,467,796 		JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 involved_in ISO PMID:1527051 RGD
UniProt		 PMID:1527051 PMID:12185001 PMID:15141107 RGD:10047264 RGD:2303392 RGD:724728 NCBI chr 1:214,931,514...215,452,739 JBrowse link
G GNAI2 G protein subunit alpha i2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11299198) Ensembl
MGI		 PMID:11299198 GO_REF:0000107 NCBI chr 3:50,154,731...50,187,948
Ensembl chr 3:51,398,981...51,421,988 		JBrowse link
G PLCB1 phospholipase C beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:8,106,665...8,858,572
Ensembl chr20:7,887,960...8,636,019 		JBrowse link
G RGS10 regulator of G protein signaling 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:116,070,326...116,113,422
Ensembl chr10:119,492,159...119,534,443 		JBrowse link
G RGS8 regulator of G protein signaling 8 involved_in ISO PMID:9394004 UniProt PMID:9394004 RGD:69963 NCBI chr 1:158,160,368...158,268,521
Ensembl chr 1:161,813,540...161,855,027 		JBrowse link
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM1 cholinergic receptor muscarinic 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:58,261,476...58,274,685
Ensembl chr11:61,614,818...61,616,200 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:128,827,089...128,978,496
Ensembl chr 7:141,466,396...141,467,796 		JBrowse link
G CHRM4 cholinergic receptor muscarinic 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7916637) Ensembl
MGI
TreeGrafter		 PMID:7916637 GO_REF:0000107 GO_REF:0000118 NCBI chr11:46,342,384...46,350,366
Ensembl chr11:46,894,615...46,896,054 		JBrowse link
G CHRM5 cholinergic receptor muscarinic 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:12,478,656...12,575,512
Ensembl chr15:31,406,198...31,407,796 		JBrowse link
G HRH3 histamine receptor H3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:58,581,228...58,586,585
Ensembl chr20:59,901,327...59,909,901 		JBrowse link
G HRH4 histamine receptor H4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:17,711,852...17,731,500
Ensembl chr18:21,332,651...21,351,930 		JBrowse link
G OPRM1 opioid receptor mu 1 involved_in ISO PMID:8051154 GO_Central PMID:8051154 RGD:8656009 NCBI chr 6:151,827,323...151,937,658
Ensembl chr 6:156,517,661...157,088,251 		JBrowse link
phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA7 annexin A7 acts_upstream_of_or_within_positive_effect ISO (PMID:10570150) MGI PMID:10570150 NCBI chr10:69,923,353...69,962,980
Ensembl chr10:72,381,447...72,420,749 		JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 involved_in ISO (PMID:20440069)
(PMID:16753580)		 MGI PMID:16753580 PMID:20440069 NCBI chr 1:214,931,514...215,452,739 JBrowse link
G GNA11 G protein subunit alpha 11 involved_in ISO (PMID:20440069) MGI PMID:20440069 NCBI chr19:2,120,398...2,149,161
Ensembl chr19:3,074,483...3,102,124 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:4,448,574...4,802,545
Ensembl chr 3:4,572,921...4,904,811 		JBrowse link
G LOC100986730 guanine nucleotide-binding protein G(q) subunit alpha involved_in ISO (PMID:20440069) MGI PMID:20440069 NCBI chr 9:46,816,409...47,129,116
Ensembl chr 9:76,575,815...76,773,849 		JBrowse link
G PLCB1 phospholipase C beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:8,106,665...8,858,572
Ensembl chr20:7,887,960...8,636,019 		JBrowse link
G PRKCB protein kinase C beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:13,888,936...14,268,759
Ensembl chr16:24,091,289...24,466,203 		JBrowse link
G STIM1 stromal interaction molecule 1 involved_in ISO (PMID:18452988) MGI PMID:18452988 NCBI chr11:3,726,501...3,954,951
Ensembl chr11:3,840,513...4,065,224 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    cellular process 15499
      signal transduction 5440
        G protein-coupled receptor signaling pathway 1064
          G protein-coupled acetylcholine receptor signaling pathway 19
            G protein-coupled acetylcholine receptor signaling pathway involved in heart process + 0
            G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission 0
            adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway 7
            phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway 8
Path 2
Term Annotations click to browse term
  biological_process 16440
    biological regulation 11453
      regulation of biological process 11104
        signaling 5935
          cell-cell signaling 1334
            synaptic signaling 867
              postsynaptic signal transduction 53
                acetylcholine receptor signaling pathway 35
                  G protein-coupled acetylcholine receptor signaling pathway 19
                    G protein-coupled acetylcholine receptor signaling pathway involved in heart process + 0
                    G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission 0
                    adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway 7
                    phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway 8
paths to the root