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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:dopamine receptor signaling pathway
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Accession:GO:0007212 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.
Synonyms:exact_synonym: dopamine receptor signalling pathway

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dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy6 adenylate cyclase 6 involved_in ISO (PMID:18403039) BHF-UCL PMID:18403039 NCBI chrNW_004955500:7,635,946...7,655,579
Ensembl chrNW_004955500:7,637,089...7,651,162 		JBrowse link
G Arpp19 cAMP regulated phosphoprotein 19 ISO RGD PMID:2158525 RGD:70802 NCBI chrNW_004955409:2,354,988...2,369,846
Ensembl chrNW_004955409:2,354,988...2,369,846 		JBrowse link
G Drd1 dopamine receptor D1 acts_upstream_of_or_within ISO (PMID:11089973)
(PMID:16908842)
(PMID:12097513)		 MGI PMID:11089973 PMID:12097513 PMID:16908842 NCBI chrNW_004955408:28,003,229...28,006,595
Ensembl chrNW_004955408:28,003,229...28,006,595 		JBrowse link
G Drd2 dopamine receptor D2 acts_upstream_of ISO (PMID:12097513) RGD
MGI		 PMID:12097513 PMID:12121979 RGD:1581445 NCBI chrNW_004955412:15,054,255...15,114,558
Ensembl chrNW_004955412:15,054,038...15,114,573 		JBrowse link
G Drd3 dopamine receptor D3 acts_upstream_of ISO (PMID:15016423)
(PMID:12097513)		 MGI PMID:12097513 PMID:15016423 NCBI chrNW_004955427:14,219,519...14,252,178
Ensembl chrNW_004955427:14,219,594...14,252,178 		JBrowse link
G Drd4 dopamine receptor D4 involved_in ISO (PMID:1840645) RGD
BHF-UCL		 PMID:1840645 PMID:12711714 RGD:1358607 NCBI chrNW_004955476:11,424,347...11,426,962
Ensembl chrNW_004955476:11,424,411...11,426,960 		JBrowse link
G Drd5 dopamine receptor D5 ISO RGD PMID:1831904 RGD:728422 NCBI chrNW_004955514:5,450,495...5,452,282 JBrowse link
G Gnai3 G protein subunit alpha i3 involved_in ISO (PMID:19478087) UniProt PMID:19478087 NCBI chrNW_004955435:12,965,006...13,005,614
Ensembl chrNW_004955435:12,965,006...13,005,614 		JBrowse link
G Gnao1 G protein subunit alpha o1 acts_upstream_of_or_within ISO (PMID:11248120) MGI PMID:11248120 NCBI chrNW_004955433:14,004,813...14,170,631
Ensembl chrNW_004955433:14,004,813...14,172,707 		JBrowse link
G Gnb5 G protein subunit beta 5 involved_in ISO (PMID:27677260) UniProt PMID:27677260 NCBI chrNW_004955409:2,621,144...2,642,298
Ensembl chrNW_004955409:2,619,718...2,641,308 		JBrowse link
G Htt huntingtin acts_upstream_of_or_within ISO (PMID:17715336) MGI PMID:17715336 NCBI chrNW_004955514:1,906,189...2,042,357
Ensembl chrNW_004955514:1,906,502...2,038,889 		JBrowse link
G Klf16 KLF transcription factor 16 acts_upstream_of_or_within ISO (PMID:11390978) MGI PMID:11390978 NCBI chrNW_004955495:6,178,565...6,189,469 JBrowse link
G Ncstn nicastrin acts_upstream_of_or_within ISO (PMID:27008863) MGI PMID:27008863 NCBI chrNW_004955468:12,111,078...12,126,404
Ensembl chrNW_004955468:12,111,078...12,127,033 		JBrowse link
G Rgs9 regulator of G protein signaling 9 ISO RGD PMID:15534226 RGD:1599997 NCBI chrNW_004955478:4,614,730...4,683,152
Ensembl chrNW_004955478:4,614,701...4,683,167 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO (PMID:28507136), (PMID:29229708) MGI PMID:28507136 PMID:29229708 NCBI chrNW_004955434:8,790,685...8,879,757
Ensembl chrNW_004955434:8,790,685...8,879,757 		JBrowse link
adenylate cyclase-activating dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd1 dopamine receptor D1 acts_upstream_of_or_within
involved_in		 ISO (PMID:17194762)
(PMID:12223546)
(PMID:9016340)
(PMID:11923452), (PMID:12665504), (PMID:8738226)
(PMID:33571431)
(MGI:6158770|PMID:23842570)
PMID:18424554
PMID:8702641
(PMID:1282671), (PMID:17760784), (PMID:18403039), (PMID:2144334), (PMID:2168520), (PMID:7838121)		 RGD
MGI
ARUK-UCL
UniProt
BHF-UCL		 PMID:1282671 PMID:2144334 PMID:2168520 PMID:7838121 PMID:8702641 More... MGI:6158770 RGD:1581394 RGD:7248551 RGD:8553617 RGD:8554146 NCBI chrNW_004955408:28,003,229...28,006,595
Ensembl chrNW_004955408:28,003,229...28,006,595 		JBrowse link
G Drd3 dopamine receptor D3 involved_in
acts_upstream_of_or_within		 ISO (PMID:18424554)
(PMID:16386234)		 BHF-UCL
MGI		 PMID:16386234 PMID:18424554 NCBI chrNW_004955427:14,219,519...14,252,178
Ensembl chrNW_004955427:14,219,594...14,252,178 		JBrowse link
G Drd5 dopamine receptor D5 involved_in ISO (PMID:1826762), (PMID:18403039) RGD
UniProt		 PMID:1826762 PMID:12688394 PMID:15328036 PMID:18403039 RGD:1581394 RGD:1600979 NCBI chrNW_004955514:5,450,495...5,452,282 JBrowse link
G Gnal G protein subunit alpha L acts_upstream_of_or_within ISO (PMID:17194762) MGI PMID:17194762 NCBI chrNW_004955402:1,182,515...1,249,301
Ensembl chrNW_004955402:1,181,133...1,248,616 		JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 acts_upstream_of_or_within ISO (PMID:20200151) MGI PMID:20200151 NCBI chrNW_004955553:1,639,267...1,656,850
Ensembl chrNW_004955553:1,639,267...1,656,850 		JBrowse link
G Oprd1 opioid receptor delta 1 NOT|acts_upstream_of_or_within ISO (PMID:8738226) MGI PMID:8738226 NCBI chrNW_004955452:7,866,790...7,913,399
Ensembl chrNW_004955452:7,866,758...7,913,399 		JBrowse link
G Oprm1 opioid receptor mu 1 acts_upstream_of_or_within ISO (PMID:8738226) MGI PMID:8738226 NCBI chrNW_004955439:7,870,563...7,923,817
Ensembl chrNW_004955439:7,757,569...7,923,817 		JBrowse link
G Ptger1 prostaglandin E receptor 1 involved_in ISO (MGI:6158770|PMID:23842570) UniProt PMID:23842570 MGI:6158770 NCBI chrNW_004955415:33,063,052...33,067,580
Ensembl chrNW_004955415:33,063,052...33,067,580 		JBrowse link
adenylate cyclase-inhibiting dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 involved_in
acts_upstream_of_or_within		 ISO (PMID:1331329), (PMID:2531656), (PMID:26554819), (PMID:8666994)
(PMID:12223546)
(PMID:12665504)
PMID:2410769		 BHF-UCL
MGI		 PMID:1331329 PMID:2410769 PMID:2531656 PMID:8666994 PMID:12223546 More... RGD:8553953 NCBI chrNW_004955412:15,054,255...15,114,558
Ensembl chrNW_004955412:15,054,038...15,114,573 		JBrowse link
G Drd3 dopamine receptor D3 involved_in ISO (PMID:18424554), (PMID:7907363), (PMID:8666994)
PMID:8302280		 BHF-UCL PMID:7907363 PMID:8302280 PMID:8666994 PMID:18424554 RGD:8554810 NCBI chrNW_004955427:14,219,519...14,252,178
Ensembl chrNW_004955427:14,219,594...14,252,178 		JBrowse link
G Drd4 dopamine receptor D4 involved_in
acts_upstream_of_or_within		 ISO (PMID:7512953), (PMID:9003072), (PMID:9843378)
(PMID:14684868)
(PMID:27659709)		 UniProt
MGI		 PMID:7512953 PMID:9003072 PMID:9843378 PMID:14684868 PMID:27659709 NCBI chrNW_004955476:11,424,347...11,426,962
Ensembl chrNW_004955476:11,424,411...11,426,960 		JBrowse link
G Flna filamin A involved_in ISO (PMID:10692483) BHF-UCL PMID:10692483 NCBI chrNW_004955580:874,233...895,172
Ensembl chrNW_004955580:874,233...895,232 		JBrowse link
negative regulation of dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO (PMID:12097513) MGI PMID:12097513 NCBI chrNW_004955412:15,054,255...15,114,558
Ensembl chrNW_004955412:15,054,038...15,114,573 		JBrowse link
G Drd3 dopamine receptor D3 acts_upstream_of_or_within ISO (PMID:12097513) MGI PMID:12097513 NCBI chrNW_004955427:14,219,519...14,252,178
Ensembl chrNW_004955427:14,219,594...14,252,178 		JBrowse link
G Palm paralemmin involved_in ISO (PMID:16386234) UniProt PMID:16386234 NCBI chrNW_004955495:7,044,942...7,060,022
Ensembl chrNW_004955495:7,046,261...7,055,548 		JBrowse link
G Rgs4 regulator of G protein signaling 4 ISO RGD PMID:21896332 RGD:13524519 NCBI chrNW_004955462:13,340,812...13,347,598
Ensembl chrNW_004955462:13,338,960...13,347,610 		JBrowse link
phospholipase C-activating dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd1 dopamine receptor D1 involved_in
acts_upstream_of_or_within		 ISO (PMID:1282671)
(PMID:15016423)
(PMID:17194762)		 BHF-UCL
MGI		 PMID:1282671 PMID:15016423 PMID:17194762 NCBI chrNW_004955408:28,003,229...28,006,595
Ensembl chrNW_004955408:28,003,229...28,006,595 		JBrowse link
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO (PMID:17194762)
(PMID:15016423)		 MGI PMID:15016423 PMID:17194762 NCBI chrNW_004955412:15,054,255...15,114,558
Ensembl chrNW_004955412:15,054,038...15,114,573 		JBrowse link
G Gna11 G protein subunit alpha 11 acts_upstream_of_or_within ISO (PMID:17194762) MGI PMID:17194762 NCBI chrNW_004955495:5,286,891...5,302,631
Ensembl chrNW_004955495:5,285,380...5,302,631 		JBrowse link
G Gnaq G protein subunit alpha q acts_upstream_of_or_within ISO (PMID:17194762) MGI PMID:17194762 NCBI chrNW_004955512:1,381,159...1,658,409 JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 acts_upstream_of_or_within ISO (PMID:20200151) MGI PMID:20200151 NCBI chrNW_004955553:1,639,267...1,656,850
Ensembl chrNW_004955553:1,639,267...1,656,850 		JBrowse link
positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prmt5 protein arginine methyltransferase 5 involved_in ISO (PMID:26554819) WB PMID:26554819 NCBI chrNW_004955409:37,369,507...37,378,034
Ensembl chrNW_004955409:37,369,234...37,378,093 		JBrowse link
positive regulation of dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav2 caveolin 2 involved_in ISO (PMID:15569306) BHF-UCL PMID:15569306 NCBI chrNW_004955432:22,240,041...22,242,200 JBrowse link
G Drd3 dopamine receptor D3 acts_upstream_of_or_within ISO (PMID:15016423) MGI PMID:15016423 NCBI chrNW_004955427:14,219,519...14,252,178
Ensembl chrNW_004955427:14,219,594...14,252,178 		JBrowse link
G Lrrk2 leucine rich repeat kinase 2 involved_in ISO (PMID:20659558) BHF-UCL PMID:20659558 NCBI chrNW_004955505:84,324...216,923
Ensembl chrNW_004955505:81,796...216,923 		JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (PMID:27460146) ParkinsonsUK-UCL PMID:27460146 NCBI chrNW_004955448:207,582...240,264
Ensembl chrNW_004955448:204,991...240,160 		JBrowse link
regulation of dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alk ALK receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:17487225) MGI PMID:17487225 NCBI chrNW_004955469:11,049,373...11,751,235
Ensembl chrNW_004955469:11,047,048...11,548,233 		JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 involved_in ISO PMID:17989303 UniProt PMID:17989303 RGD:8553895 NCBI chrNW_004955590:276,143...382,812
Ensembl chrNW_004955590:281,704...386,189 		JBrowse link
G Lrrk2 leucine rich repeat kinase 2 involved_in ISO (MGI:5553024|PMID:24464040) ParkinsonsUK-UCL PMID:24464040 MGI:5553024 NCBI chrNW_004955505:84,324...216,923
Ensembl chrNW_004955505:81,796...216,923 		JBrowse link
G Rgs8 regulator of G protein signaling 8 involved_in ISO PMID:9394004 UniProt PMID:9394004 RGD:69963 NCBI chrNW_004955406:21,482,810...21,523,518
Ensembl chrNW_004955406:21,482,810...21,523,674 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    cellular process 11480
      signal transduction 3950
        dopamine receptor signaling pathway 32
          adenylate cyclase-activating dopamine receptor signaling pathway 8
          adenylate cyclase-inhibiting dopamine receptor signaling pathway + 5
          negative regulation of dopamine receptor signaling pathway + 4
          phospholipase C-activating dopamine receptor signaling pathway + 5
          positive regulation of dopamine receptor signaling pathway + 5
          regulation of dopamine receptor signaling pathway + 11
Path 2
Term Annotations click to browse term
  biological_process 12346
    response to stimulus 6681
      cellular response to stimulus 5381
        cellular response to chemical stimulus 2540
          cellular response to organic substance 1942
            cellular response to organonitrogen compound 662
              cellular response to monoamine stimulus 54
                cellular response to catecholamine stimulus 52
                  cellular response to dopamine 44
                    dopamine receptor signaling pathway 32
                      adenylate cyclase-activating dopamine receptor signaling pathway 8
                      adenylate cyclase-inhibiting dopamine receptor signaling pathway + 5
                      negative regulation of dopamine receptor signaling pathway + 4
                      phospholipase C-activating dopamine receptor signaling pathway + 5
                      positive regulation of dopamine receptor signaling pathway + 5
                      regulation of dopamine receptor signaling pathway + 11
paths to the root